Michela Faggioni, MD
Assistant Professor
Clinical Interests
Dr. Michela Faggioni is an interventional cardiologist, a specialist in minimally invasive procedures to address heart conditions. She treats acute and chronic coronary syndromes (conditions in which blood flow to the heart is suddenly reduced) and heart valve diseases. In addition, she performs left atrial appendage occlusions (closing a small pouch in the heart’s upper left chamber to prevent clots), patent foramen ovale occlusions (closing a hole between the heart's upper chambers to prevent clots) and renal denervations (destroying nerves in arteries supplying the kidneys as a treatment for high blood pressure).
Research Interests
Dr Faggioni’s research focuses on ways to improve clinical outcomes for patients having interventional cardiology procedures.
Education
Publications
Fanaroff AC, Faggioni M. Managing Myocardial Infarction in the Age of Multimorbidity. Volume 82 of Issue 10. Journal of the American College of Cardiology 2023. PMID: 37648356
Reddy KP, Faggioni M, Eberly LA, Halaby R, Sanghavi M, Lewey J, Mehran R, Coylewright M, Herrmann HC, Giri J, Fanaroff AC, Nathan AS. Enrollment of Older Patients, Women, and Racial and Ethnic Minority Individuals in Valvular Heart Disease Clinical Trials: A Systematic Review. Volume 8 of Issue 9. JAMA cardiology 2023. PMID: 37494015
Hirshfeld JW, Faggioni M. Optimizing Coronary Interventional Procedure Outcomes: Experience Matters, Intravascular Ultrasound Helps. Volume 16 of Issue 14. JACC. Cardiovascular interventions 2023. PMID: 37495351
Zaid S, Attizzani GF, Krishnamoorthy P, Yoon SH, Palma Dallan LA, Chetcuti S, Fukuhara S, Grossman PM, Goel SS, Atkins MD, Kleiman NS, Puri R, Bakhtadze B, Byrne T, Ibrahim AW, Grubb KJ, Tully A, Herrmann HC, Faggioni M, Ramlawi B, Khera S, Lerakis S, Dangas GD, Kini AS, Sharma SK, Reardon MJ, Tang GHL. First-in-Human Multicenter Experience of the Newest Generation Supra-Annular Self-Expanding Evolut FX TAVR System. Volume 16 of Issue 13. JACC. Cardiovascular interventions 2023. PMID: 37438029
Blackwell DJ, Faggioni M, Wleklinski MJ, Gomez-Hurtado N, Venkataraman R, Gibbs CE, Baudenbacher FJ, Gong S, Fishman GI, Boyle PM, Pfeifer K, Knollmann BC. The Purkinje-myocardial junction is the anatomic origin of ventricular arrhythmia in CPVT. Volume 7 of Issue 3. JCI insight 2022. PMID: 34990403
Faggioni M, Fanaroff AC. Seeking patient-centered trial outcomes: The case for days alive out of hospital. Volume 248. American heart journal 2021. PMID: 34019888
Tarantino N, Della Rocca DG, Faggioni M, Zhang XD, Mohanty S, Anannab A, Canpolat U, Ayhan H, Bassiouny M, Sahore A, Aytemir K, Sarcon A, Forleo GB, Lavalle C, Horton RP, Trivedi C, Al-Ahmad A, Romero J, Burkhardt DJ, Gallinghouse JG, Di Biase L, Natale A. Epicardial Ablation Complications. Volume 12 of Issue 3. Cardiac electrophysiology clinics 2020. PMID: 32771194
Faggioni M, Della Rocca DG, Mohanty S, Trivedi C, Canpolat U, Gianni C, Al-Ahmad A, Horton R, Gallinghouse GJ, Burkhardt JD, Natale A. Long-term Outcome of Pulmonary Vein Isolation Versus Amiodarone Therapy in Patients with Coexistent Persistent AF and Congestive Heart Failure. Volume 6. Cardiac failure review 2020. PMID: 32377383
Canpolat U, Faggioni M, Della Rocca DG, Chen Q, Ayhan H, Vu AA, Mohanty S, Trivedi C, Gianni C, Bassiouny M, Al-Ahmad A, Burkhardt JD, Sanchez JE, Gallinghouse GJ, Natale A, Horton RP. State of Fluoroless Procedures in Cardiac Electrophysiology Practice. Volume 11 of Issue 3. The Journal of Innovations in Cardiac Rhythm Management 2020. PMID: 32368376
Chandrasekhar J, Dangas G, Baber U, Sartori S, Qadeer A, Aquino M, Vogel B, Faggioni M, Vijay P, Claessen BE, Goel R, Moreno P, Krishnan P, Kovacic JC, Kini A, Mehran R, Sharma S. Impact of insulin treated and non-insulin-treated diabetes compared to patients without diabetes on 1-year outcomes following contemporary PCI. Volume 96 of Issue 2. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2020. PMID: 32162781
Faggioni M, Redfors B, Crowley A, Claessen BE, Farhan S, Mastoris I, Witzenbichler B, Maehara A, Weisz G, Généreux P, Ben-Yehuda O, Mehran R, Kirtane AJ, Stone GW. Comparison of Age (<75 Years Vs ≥75 Years) and Platelet Reactivity to the Risk of Thrombotic and Bleeding Events After Successful Percutaneous Coronary Intervention With Drug-Eluting Stents (from the ADAPT-DES Study). Volume 125 of Issue 5. The American journal of cardiology 2019. PMID: 31926634
Giannini C, Petronio AS, Mehilli J, Sartori S, Chandrasekhar J, Faggioni M, Lefèvre T, Presbitero P, Capranzano P, Tchetche D, Iadanza A, Sardella G, Van Mieghem NM, Meliga E, Dumonteil N, Fraccaro C, Trabattoni D, Mikhail GW, Ferrer MC, Naber C, Kievit P, Sorrentino S, Morice MC, Chieffo A, Mehran R, WIN-TAVI Investigators. Edwards SAPIEN Versus Medtronic Aortic Bioprosthesis in Women Undergoing Transcatheter Aortic Valve Implantation (from the Win-TAVI Registry). Volume 125 of Issue 3. The American journal of cardiology 2019. PMID: 31813530
Hwang HS, Baldo MP, Rodriguez JP, Faggioni M, Knollmann BC. Efficacy of Flecainide in Catecholaminergic Polymorphic Ventricular Tachycardia Is Mutation-Independent but Reduced by Calcium Overload. Volume 10. Frontiers in physiology 2019. PMID: 31456692
Vogel B, Chandrasekhar J, Baber U, Mastoris I, Sartori S, Aquino M, Krucoff MW, Moliterno DJ, Henry TD, Weisz G, Gibson CM, Iakovou I, Kini AS, Farhan S, Sorrentino S, Faggioni M, Colombo A, Steg PG, Witzenbichler B, Chieffo A, Cohen DJ, Stuckey T, Ariti C, Dangas GD, Pocock S, Mehran R. Geographical Variations in Patterns of DAPT Cessation and Two-Year PCI Outcomes: Insights from the PARIS Registry. Volume 119 of Issue 10. Thrombosis and haemostasis 2019. PMID: 31365942
Joyce LC, Baber U, Claessen BE, Sartori S, Chandrasekhar J, Cohen DJ, Henry TD, Ariti C, Dangas G, Faggioni M, Aoi S, Gibson CM, Aquino M, Krucoff MW, Vogel B, Moliterno DJ, Sorrentino S, Colombo A, Chieffo A, Kini A, Guedeney P, Witzenbichler B, Weisz G, Steg PG, Pocock S, Mehran R. Dual-Antiplatelet Therapy Cessation and Cardiovascular Risk in Relation to Age: Analysis From the PARIS Registry. Volume 12 of Issue 10. JACC. Cardiovascular interventions 2019. PMID: 31122354
Faggioni M, Baber U, Sartori S, Chandrasekhar J, Cohen DJ, Henry TD, Claessen BE, Dangas GD, Gibson CM, Krucoff MW, Vogel B, Moliterno DJ, Sorrentino S, Colombo A, Chieffo A, Kini A, Farhan S, Ariti C, Witzenbichler B, Weisz G, Steg PG, Pocock S, Mehran R. Influence of Baseline Anemia on Dual Antiplatelet Therapy Cessation and Risk of Adverse Events After Percutaneous Coronary Intervention. Volume 12 of Issue 4. Circulation. Cardiovascular interventions 2019. PMID: 30998384
Faggioni M, Baber U, Chandrasekhar J, Sartori S, Weintraub W, Rao SV, Vogel B, Claessen B, Kini A, Effron M, Ge Z, Keller S, Strauss C, Snyder C, Toma C, Weiss S, Aquino M, Baker B, Defranco A, Bansilal S, Muhlestein B, Kapadia S, Pocock S, Poddar KL, Henry TD, Mehran R. Use of prasugrel and clinical outcomes in African-American patients treated with percutaneous coronary intervention for acute coronary syndromes. Volume 94 of Issue 1. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2019. PMID: 30656812
Faggioni M, Baber U, Chandrasekhar J, Sartori S, Claessen BE, Rao SV, Vogel B, Effron MB, Poddar K, Farhan S, Kini A, Weintraub W, Toma C, Sorrentino S, Weiss S, Snyder C, Muhlestein JB, Kapadia S, Keller S, Strauss C, Aquino M, Baker B, Defranco A, Pocock S, Henry T, Mehran R. Use of prasugrel vs clopidogrel and outcomes in patients with and without diabetes mellitus presenting with acute coronary syndrome undergoing percutaneous coronary intervention. Volume 275. International journal of cardiology 2018. PMID: 30391067
Ge Z, Baber U, Claessen BE, Farhan S, Chandrasekhar J, Li SX, Sartori S, Kini AS, Rao SV, Weiss S, Henry TD, Vogel B, Sorrentino S, Faggioni M, Kapadia S, Muhlestein B, Strauss C, Toma C, DeFranco A, Effron MB, Keller S, Baker BA, Pocock S, Dangas G, Mehran R. The prevalence, predictors and outcomes of guideline-directed medical therapy in patients with acute myocardial infarction undergoing PCI, an analysis from the PROMETHEUS registry. Volume 93 of Issue 3. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2018. PMID: 30351514
Guedeney P, Baber U, Claessen B, Aquino M, Camaj A, Sorrentino S, Vogel B, Farhan S, Faggioni M, Chandrasekhar J, Kalkman DN, Kovacic JC, Sweeny J, Barman N, Moreno P, Vijay P, Shah S, Dangas G, Kini A, Sharma S, Mehran R. Temporal trends, determinants, and impact of high-intensity statin prescriptions after percutaneous coronary intervention: Results from a large single-center prospective registry. Volume 207. American heart journal 2018. PMID: 30404046
Mehran R, Faggioni M, Chandrasekhar J, Angiolillo DJ, Bertolet B, Jobe RL, Al-Joundi B, Brar S, Dangas G, Batchelor W, Prasad A, Gurm HS, Tumlin J, Stone GW. Effect of a Contrast Modulation System on Contrast Media Use and the Rate of Acute Kidney Injury After Coronary Angiography. Volume 11 of Issue 16. JACC. Cardiovascular interventions 2018. PMID: 30139467
Sorrentino S, Giustino G, Baber U, Sartori S, Cohen DJ, Henry TD, Farhan S, Sharma M, Ariti C, Dangas G, Gibson M, Faggioni M, Krucoff MW, Aquino M, Chandrasekhar J, Moliterno DJ, Colombo A, Vogel B, Chieffo A, Kini AS, Witzenbichler B, Weisz G, Steg PG, Pocock S, Mehran R. Dual Antiplatelet Therapy Cessation and Adverse Events After Drug-Eluting Stent Implantation in Patients at High Risk for Atherothrombosis (from the PARIS Registry). Volume 122 of Issue 10. The American journal of cardiology 2018. PMID: 30270177
Ge Z, Faggioni M, Baber U, Sartori S, Sorrentino S, Farhan S, Chandrasekhar J, Vogel B, Qadeer A, Halperin J, Reddy V, Dukkipati S, Dangas G, Mehran R. Safety and efficacy of nonvitamin K antagonist oral anticoagulants during catheter ablation of atrial fibrillation: A systematic review and meta-analysis. Volume 36 of Issue 5. Cardiovascular therapeutics 2018. PMID: 29971964
Faggioni M, Baber U, Afshar AE, Giustino G, Sartori S, Sorrentino S, Steg PG, Stefanini GG, Windecker S, Leon MB, Stone GW, Wijns W, Serruys PW, Valgimigli M, Camenzind E, Weisz G, Smits PC, Kandzari DE, Galatius S, Von Birgelen C, Jeger RV, Mikhail GW, Itchhaporia D, Mehta L, Ortega R, Kim HS, Kastrati A, Chieffo A, Dangas GD, Morice MC, Mehran R. Effects of Body Mass Index on Clinical Outcomes in Female Patients Undergoing Percutaneous Coronary Intervention With Drug-Eluting Stents: Results From a Patient-Level Pooled Analysis of Randomized Controlled Trials. Volume 11 of Issue 1. JACC. Cardiovascular interventions 2017. PMID: 29248412
Baber U, Chandrasekhar J, Sartori S, Aquino M, Kini AS, Kapadia S, Weintraub W, Muhlestein JB, Vogel B, Faggioni M, Farhan S, Weiss S, Strauss C, Toma C, DeFranco A, Baker BA, Keller S, Effron MB, Henry TD, Rao S, Pocock S, Dangas G, Mehran R. Associations Between Chronic Kidney Disease and Outcomes With Use of Prasugrel Versus Clopidogrel in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: A Report From the PROMETHEUS Study. Volume 10 of Issue 20. JACC. Cardiovascular interventions 2017. PMID: 28780028
Giustino G, Harari R, Baber U, Sartori S, Stone GW, Leon MB, Windecker S, Serruys PW, Kastrati A, Von Birgelen C, Kimura T, Stefanini GG, Dangas GD, Wijns W, Steg PG, Morice MC, Camenzind E, Weisz G, Smits PC, Sorrentino S, Sharma M, Farhan S, Faggioni M, Kandzari D, Galatius S, Jeger RV, Valgimigli M, Itchhaporia D, Mehta L, Kim HS, Chieffo A, Mehran R. Long-term Safety and Efficacy of New-Generation Drug-Eluting Stents in Women With Acute Myocardial Infarction: From the Women in Innovation and Drug-Eluting Stents (WIN-DES) Collaboration. Volume 2 of Issue 8. JAMA cardiology 2017. PMID: 28658478
Chandrasekhar J, Baber U, Sartori S, Aquino M, Tomey M, Kruckoff M, Moliterno D, Henry TD, Weisz G, Gibson CM, Iakovou I, Kini A, Faggioni M, Vogel B, Farhan S, Colombo A, Steg PG, Witzenbichler B, Chieffo A, Cohen D, Stuckey T, Ariti C, Pocock S, Dangas G, Mehran R. Patterns and associations between DAPT cessation and 2-year clinical outcomes in left main/proximal LAD versus other PCI: Results from the Patterns of Non-Adherence to Dual Antiplatelet Therapy in Stented Patients (PARIS) registry. Volume 243. International journal of cardiology 2017. PMID: 28554669
Sorrentino S, Giustino G, Mehran R, Kini AS, Sharma SK, Faggioni M, Farhan S, Vogel B, Indolfi C, Dangas GD. Everolimus-Eluting Bioresorbable Scaffolds Versus Everolimus-Eluting Metallic Stents. Volume 69 of Issue 25. Journal of the American College of Cardiology 2017. PMID: 28412389
Faggioni M, Baber U, Sartori S, Giustino G, Cohen DJ, Henry TD, Farhan S, Ariti C, Dangas G, Gibson M, Giacoppo D, Krucoff MW, Aquino M, Chandrasekhar J, Moliterno DJ, Colombo A, Vogel B, Chieffo A, Kini AS, Witzenbichler B, Weisz G, Steg PG, Pocock S, Mehran R. Incidence, Patterns, and Associations Between Dual-Antiplatelet Therapy Cessation and Risk for Adverse Events Among Patients With and Without Diabetes Mellitus Receiving Drug-Eluting Stents: Results From the PARIS Registry. Volume 10 of Issue 7. JACC. Cardiovascular interventions 2017. PMID: 28330641
Giustino G, Sorrentino S, Mehran R, Faggioni M, Dangas G. Cerebral Embolic Protection During TAVR: A Clinical Event Meta-Analysis. Volume 69 of Issue 4. Journal of the American College of Cardiology 2017. PMID: 28126163
Farhan S, Baber U, Vogel B, Aquino M, Chandrasekhar J, Faggioni M, Giustino G, Kautzky-Willer A, Sweeny J, Shah S, Vijay P, Barman N, Moreno P, Kovacic J, Dangas G, Kini A, Mehran R, Sharma S. Impact of Diabetes Mellitus on Ischemic Events in Men and Women After Percutaneous Coronary Intervention. Volume 119 of Issue 8. The American journal of cardiology 2017. PMID: 28236457
Mehran R, Faggioni M. CABG Beats Vintage PCI: Does Contemporary PCI Stand a Chance to EXCEL? Volume 9 of Issue 24. JACC. Cardiovascular interventions 2016. PMID: 28007202
Cortigiani L, Gherardi S, Faggioni M, Bovenzi F, Picano E, Petersen C, Molinaro S, Sicari R. Dual-Imaging Stress Echocardiography for Prognostic Assessment of High-Risk Asymptomatic Patients with Diabetes Mellitus. Volume 30 of Issue 2. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2016. PMID: 27843105
Giustino G, Mehran R, Veltkamp R, Faggioni M, Baber U, Dangas GD. Neurological Outcomes With Embolic Protection Devices in Patients Undergoing Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Volume 9 of Issue 20. JACC. Cardiovascular interventions 2016. PMID: 27765306
Faggioni M, Mehran R. Preventing Contrast-induced Renal Failure: A Guide. Volume 11 of Issue 2. Interventional cardiology (London, England) 2016. PMID: 29588714
Chandrasekhar J, Bansilal S, Baber U, Sartori S, Aquino M, Farhan S, Vogel B, Faggioni M, Giustino G, Ariti C, Colombo A, Chieffo A, Kini A, Saporito R, Michael Gibson C, Witzenbichler B, Cohen D, Moliterno D, Stuckey T, Henry T, Pocock S, Dangas G, Gabriel Steg P, Mehran R. Impact of proton pump inhibitors and dual antiplatelet therapy cessation on outcomes following percutaneous coronary intervention: Results From the PARIS Registry. Volume 89 of Issue 7. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2016. PMID: 27650638
Chieffo A, Petronio AS, Mehilli J, Chandrasekhar J, Sartori S, Lefèvre T, Presbitero P, Capranzano P, Tchetche D, Iadanza A, Sardella G, Van Mieghem NM, Meliga E, Dumonteil N, Fraccaro C, Trabattoni D, Mikhail GW, Sharma S, Ferrer MC, Naber C, Kievit P, Faggioni M, Snyder C, Morice MC, Mehran R, WIN-TAVI Investigators. Acute and 30-Day Outcomes in Women After TAVR: Results From the WIN-TAVI (Women's INternational Transcatheter Aortic Valve Implantation) Real-World Registry. Volume 9 of Issue 15. JACC. Cardiovascular interventions 2016. PMID: 27491609
Villablanca PA, Briceno DF, Massera D, Hlinomaz O, Lombardo M, Bortnick AE, Menegus MA, Pyo RT, Garcia MJ, Mookadam F, Ramakrishna H, Wiley J, Faggioni M, Dangas GD. Culprit-lesion only versus complete multivessel percutaneous intervention in ST-elevation myocardial infarction: A systematic review and meta-analysis of randomized trials. Volume 220. International journal of cardiology 2016. PMID: 27390938
Chandrasekhar J, Baber U, Sartori S, Faggioni M, Aquino M, Kini A, Weintraub W, Rao S, Kapadia S, Weiss S, Strauss C, Toma C, Muhlestein B, DeFranco A, Effron M, Keller S, Baker B, Pocock S, Henry T, Mehran R. Sex-related differences in outcomes among men and women under 55 years of age with acute coronary syndrome undergoing percutaneous coronary intervention: Results from the PROMETHEUS study. Volume 89 of Issue 4. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2016. PMID: 27152497
Faggioni M, Mehran R. Target lesion failure with BRS? good old DES to the rescue. Volume 87 of Issue 5. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2016. PMID: 27085024
Giustino G, Faggioni M, Mehran R. Advances in dual therapy stenting. Volume 64 of Issue 2. Minerva cardioangiologica 2016. PMID: 26934661
Giannini C, Fiorelli F, De Carlo M, Guarracino F, Faggioni M, Giordano P, Spontoni P, Pieroni A, Petronio AS. Comparison of Percutaneous Mitral Valve Repair Versus Conservative Treatment in Severe Functional Mitral Regurgitation. Volume 117 of Issue 2. The American journal of cardiology 2015. PMID: 26651454
Faggioni M, Knollmann BC. Arrhythmia Protection in Hypokalemia: A Novel Role of Ca2+-Activated K+ Currents in the Ventricle. Volume 132 of Issue 15. Circulation 2015. PMID: 26362635
Faggioni M, van der Werf C, Knollmann BC. Sinus node dysfunction in catecholaminergic polymorphic ventricular tachycardia: risk factor and potential therapeutic target? Volume 24 of Issue 7. Trends in cardiovascular medicine 2014. PMID: 25112803
Hwang HS, Nitu FR, Yang Y, Walweel K, Pereira L, Johnson CN, Faggioni M, Chazin WJ, Laver D, George AL, Cornea RL, Bers DM, Knollmann BC. Divergent regulation of ryanodine receptor 2 calcium release channels by arrhythmogenic human calmodulin missense mutants. Volume 114 of Issue 7. Circulation research 2014. PMID: 24563457
Faggioni M, Savio-Galimberti E, Venkataraman R, Hwang HS, Kannankeril PJ, Darbar D, Knollmann BC. Suppression of spontaneous ca elevations prevents atrial fibrillation in calsequestrin 2-null hearts. Volume 7 of Issue 2. Circulation. Arrhythmia and electrophysiology 2014. PMID: 24493699
Huke S, Venkataraman R, Faggioni M, Bennuri S, Hwang HS, Baudenbacher F, Knollmann BC. Focal energy deprivation underlies arrhythmia susceptibility in mice with calcium-sensitized myofilaments. Volume 112 of Issue 10. Circulation research 2013. PMID: 23532597
Faggioni M, Hwang HS, van der Werf C, Nederend I, Kannankeril PJ, Wilde AA, Knollmann BC. Accelerated sinus rhythm prevents catecholaminergic polymorphic ventricular tachycardia in mice and in patients. Volume 112 of Issue 4. Circulation research 2013. PMID: 23295832
Faggioni M, Kryshtal DO, Knollmann BC. Calsequestrin mutations and catecholaminergic polymorphic ventricular tachycardia. Volume 33 of Issue 6. Pediatric cardiology 2012. PMID: 22421959
Faggioni M, Knollmann BC. Calsequestrin 2 and arrhythmias. Volume 302 of Issue 6. American journal of physiology. Heart and circulatory physiology 2011. PMID: 22198169
Campan M, Lionetti V, Aquaro GD, Forini F, Matteucci M, Vannucci L, Chiuppesi F, Di Cristofano C, Faggioni M, Maioli M, Barile L, Messina E, Lombardi M, Pucci A, Pistello M, Recchia FA. Ferritin as a reporter gene for in vivo tracking of stem cells by 1.5-T cardiac MRI in a rat model of myocardial infarction. Volume 300 of Issue 6. American journal of physiology. Heart and circulatory physiology 2011. PMID: 21335465
Hwang HS, Hasdemir C, Laver D, Mehra D, Turhan K, Faggioni M, Yin H, Knollmann BC. Inhibition of cardiac Ca2+ release channels (RyR2) determines efficacy of class I antiarrhythmic drugs in catecholaminergic polymorphic ventricular tachycardia. Volume 4 of Issue 2. Circulation. Arrhythmia and electrophysiology 2011. PMID: 21270101