Reactivation of Fetal Hemoglobin for Therapy: Status and Current Challenges
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The Rudi Schmid Lecture
Reactivation of Fetal Hemoglobin for Therapy: Status and Current Challenges
Session moderated by Lekshmi Santhosh
Exciting new advances are underway for the treatment of patients with blood disorders such as sickle cell anemia and thalassemia. Understanding the basic science behind the mechanisms regulating fetal hemoglobin (HbF) is critical to exploring these novel therapeutics. Innovative research conducted at the Orkin lab has led to advancements in techniques for re-expressing HbF in adult red blood cells. In our annual Rudi Schmid Lecture, Stuart Orkin, MD, a Howard Hughes Medical Institute Investigator, will discuss the challenges and recent progress in using HbF reactivation as a therapeutic approach for hematologic diseases.
Speaker: Stuart Orkin, MD, is the David G. Nathan Distinguished Professor of Pediatrics at Harvard Medical School, a member of the National Academy of Sciences and the Institute of Medicine, and a Howard Hughes Medical Institute Investigator. The Orkin lab uses multidisciplinary approaches to study the genetic basis of blood disorders, including the development and function of the blood system, the relationship between cancer and stem cells, the mechanisms responsible for self-renewal of stem cells, and the switch from fetal to adult hemoglobin.
The Rudi Schmid Lecture is held in honor of Rudi Schmid, MD, PhD. Born in Switzerland, Schmid received his MD degree from the University of Zurich in 1947. After an internship at UCSF and residency at the University of Minnesota, he became a faculty member at the NIH, Harvard, and the University of Chicago before joining our UCSF faculty in 1966 as professor and chief of gastroenterology. Under his leadership, our GI division became one of the country’s leading research, educational, and clinical gastroenterology and hepatology units. As dean of the UCSF School of Medicine from 1983-1989, Schmid fostered the continued growth of both basic and clinical sciences. He served as president of several professional organizations, including the American Association for the Study of Liver Diseases, and received many national and international awards in recognition of outstanding achievements throughout his career.
How to Attend
In Person:
S-214 (Medical Sciences Building)
Lunch will be provided
By Phone (for higher quality, dial a number based on your current location):
US: +1 669 900 6833 or +1 213 338 8477 or +1 669 219 2599
International numbers available: https://ucsf.zoom.us/u/abt1xcyvsc
Add to Calendar2024-12-10 20:00:002024-12-10 21:00:00Reactivation of Fetal Hemoglobin for Therapy: Status and Current Challenges
The Rudi Schmid Lecture
Reactivation of Fetal Hemoglobin for Therapy: Status and Current Challenges
Session moderated by Lekshmi Santhosh
Exciting new advances are underway for the treatment of patients with blood disorders such as sickle cell anemia and thalassemia. Understanding the basic science behind the mechanisms regulating fetal hemoglobin (HbF) is critical to exploring these novel therapeutics. Innovative research conducted at the Orkin lab has led to advancements in techniques for re-expressing HbF in adult red blood cells. In our annual Rudi Schmid Lecture, Stuart Orkin, MD, a Howard Hughes Medical Institute Investigator, will discuss the challenges and recent progress in using HbF reactivation as a therapeutic approach for hematologic diseases.
Speaker:
Stuart Orkin, MD, is the David G. Nathan Distinguished Professor of Pediatrics at Harvard Medical School, a member of the National Academy of Sciences and the Institute of Medicine, and a Howard Hughes Medical Institute Investigator. The Orkin lab uses multidisciplinary approaches to study the genetic basis of blood disorders, including the development and function of the blood system, the relationship between cancer and stem cells, the mechanisms responsible for self-renewal of stem cells, and the switch from fetal to adult hemoglobin.
The Rudi Schmid Lecture is held in honor of Rudi Schmid, MD, PhD. Born in Switzerland, Schmid received his MD degree from the University of Zurich in 1947. After an internship at UCSF and residency at the University of Minnesota, he became a faculty member at the NIH, Harvard, and the University of Chicago before joining our UCSF faculty in 1966 as professor and chief of gastroenterology. Under his leadership, our GI division became one of the country’s leading research, educational, and clinical gastroenterology and hepatology units. As dean of the UCSF School of Medicine from 1983-1989, Schmid fostered the continued growth of both basic and clinical sciences. He served as president of several professional organizations, including the American Association for the Study of Liver Diseases, and received many national and international awards in recognition of outstanding achievements throughout his career.
How to Attend
In Person:
S-214 (Medical Sciences Building)
Lunch will be provided
On Zoom:
Join from a PC, Mac, iPad, iPhone or Android device:
https://ucsf.zoom.us/j/97645766587?pwd=OpxbkAwpMENJgLN8xpPHofjwzHD8JH.1
Webinar ID: 976 4576 6587
Passcode: 364678
By Phone (for higher quality, dial a number based on your current location):
US: +1 669 900 6833 or +1 213 338 8477 or +1 669 219 2599
International numbers available: https://ucsf.zoom.us/u/abt1xcyvsc
The session will be recorded for later play. See all past recordings.
Department of MedicineAmerica/Los_Angelespublic
