Lisa Rotenstein, MD, MBA

Assistant Clinical Professor

Medicine Home, General Internal Medicine, General Internal Medicine UCSF Health

Dr. Rotenstein is a primary care physician, researcher and healthcare leader whose work focuses on ambulatory care delivery, physician wellbeing, gender issues in medicine, and the intersection of the electronic health record with these issues.

She is an Assistant Professor and Medical Director of Ambulatory Quality and Safety at UCSF Health. She additionally serves as the Director of the Center for Physician Experience and Practice Excellence at Brigham and Women's Hospital. She was named a 2022 Modern Healthcare Top 25 Emerging Leader, the 2022 New England Region SGIM Investigator of the Year, and a 2021 STAT Wunderkind.

Dr. Rotenstein's research on physician and trainee mental health, published in JAMA, JAMA Health Forum, and the Journal of General Internal Medicine has fostered increased awareness of the epidemic of depression and burnout in medical students and physicians and catalyzed action to address this public health burden. Her research on the electronic health record (EHR), published in JAMA Internal Medicine, JAMA Network Open, and JAMIA, have deepened our understanding of the role of the EHR in physician experience. She is a nationally recognized expert on gender issues in medicine, with her research and writing on this topic featured in the New England Journal of Medicine, the Harvard Business Review, and JAMA Internal Medicine.

Dr. Rotenstein currently is establishing and leading ambulatory quality efforts across the UCSF Health system in her role as Medical Director of Ambulatory Quality and Safety. She additionally leads quality and electronic inbox optimization efforts for the UCSF Department of Medicine. Previously, as Medical Director of Population Health at Brigham and Women's Hospital, she led population health and collaborative care initiatives across Brigham Health's primary care practices, which care for 150,000 patients. Prior to that, she led faculty development and wellbeing, population health, and job doability efforts for the Brigham and Women's Physicians Organization.

Publications
  1. Rowe KA, Carbo A, Katz JT, Rotenstein L. Customised knowledge-sharing platform to foster resident quality improvement activities, tracking and scholarship. BMJ open quality 2024. PMID: 38307702


  2. Rotenstein LS, Landman A, Bates DW. The Electronic Inbox-Benefits, Questions, and Solutions for the Road Ahead. Volume 330 of Issue 18. JAMA 2023. PMID: 37812413


  3. Rotenstein LS, Mafi JN, Landon BE. Proportion Of Preventive Primary Care Visits Nearly Doubled, Especially Among Medicare Beneficiaries, 2001-19. Volume 42 of Issue 11. Health affairs (Project Hope) 2023. PMID: 37931202


  4. Rotenstein LS, Holmgren AJ, Horn DM, Lipsitz S, Phillips R, Gitomer R, Bates DW. System-Level Factors and Time Spent on Electronic Health Records by Primary Care Physicians. JAMA network open 2023. PMID: 37991757


  5. Li H, Rotenstein L, Jeffery MM, Paek H, Nath B, Williams BL, McLean RM, Goldstein R, Nuckols TK, Hoq L, Melnick ER. Quantifying EHR and Policy Factors Associated with the Gender Productivity Gap in Ambulatory, General Internal Medicine. Journal of general internal medicine 2023. PMID: 37843702


  6. Levy DR, Moy A, Apathy N, Adler-Milstein J, Rotenstein L, Nath B, Rosenbloom T, Kannampallil T, Mishuris RG, Alexanian A, Sieja A, Hribar MR, Patel JS, Sinsky C, Melnick ER. Identifying and Addressing Barriers to Implementing Core EHR Use Metrics for Ambulatory Care: Virtual Consensus Conference Proceedings. Applied clinical informatics 2023. PMID: 37802122


  7. Zimerman A, Rotenstein LS, Jena AB. Trends in Scientific Collaboration Between Men and Women Following the #MeToo Movement. Journal of general internal medicine 2023. PMID: 37783977


  8. Rotenstein LS, Figueroa JF. Uncovering Hidden Racial and Ethnic Bias Through Electronic Health Record Logs. Volume 6 of Issue 10. JAMA network open 2023. PMID: 37812423


  9. Rotenstein L, Holmgren AJ. COVID Exacerbated the Gender Disparity in Physician Electronic Health Record Inbox Burden. Journal of the American Medical Informatics Association : JAMIA 2023. PMID: 37436709


  10. Rotenstein LS, Melnick ER, Jeffery M, Zhang J, Sinsky CA, Gitomer R, Bates DW. Association of Primary Care Physicians' Electronic Inbox Activity Patterns with Patients' Likelihood to Recommend the Physician. Journal of general internal medicine 2023. PMID: 37731135


  11. Sinha S, Holmgren AJ, Hong JC, Rotenstein LS. Ctrl-C: A Cross-Sectional Study of the EHR Usage Patterns of US Oncology Clinicians. JNCI cancer spectrum 2023. PMID: 37688578


  12. Rotenstein LS, Del Carmen MG, Dudley J. Enhancing Lactation Accommodations for Physicians-An Opportunity for Tangible Investments in Our Workforce. Volume 6 of Issue 8. JAMA network open 2023. PMID: 37552483


  13. Rotenstein L, Gitomer R, Landon B. Pursuing Gender Equity by Paying for What Matters in Primary Care. Volume 389 of Issue 3. The New England journal of medicine 2023. PMID: 37458223


  14. Rotenstein LS, Apathy N, Edgman-Levitan S, Landon B. Comparison of Work Patterns Between Physicians and Advanced Practice Practitioners in Primary Care and Specialty Practice Settings. Volume 6 of Issue 6. JAMA network open 2023. PMID: 37310739


  15. Rotenstein LS, Brown R, Sinsky C, Linzer M. The Association of Work Overload with Burnout and Intent to Leave the Job Across the Healthcare Workforce During COVID-19. Volume 38 of Issue 8. Journal of general internal medicine 2023. PMID: 36959522


  16. Hendrix N, Bazemore A, Holmgren AJ, Rotenstein LS, Eden AR, Krist AH, Phillips RL. Variation in Family Physicians' Experiences Across Different Electronic Health Record Platforms: a Descriptive Study. Journal of general internal medicine 2023. PMID: 36952084


  17. Rotenstein LS, Cohen DJ, Marino M, Bates DW, Edwards ST. Association of Clinician Practice Ownership With Ability of Primary Care Practices to Improve Quality Without Increasing Burnout. Volume 4 of Issue 3. JAMA health forum 2023. PMID: 37000432


  18. Rotenstein LS, Edwards ST, Landon BE. Adult Primary Care Physician Visits Increasingly Address Mental Health Concerns. Volume 42 of Issue 2. Health affairs (Project Hope) 2023. PMID: 36745830


  19. Mata DA, Rotenstein LS, Ramos MA, Jena AB. Disparities According to Genetic Ancestry in the Use of Precision Oncology Assays. Volume 388 of Issue 3. The New England journal of medicine 2023. PMID: 36652362


  20. Rotenstein LS, Apathy N, Holmgren AJ, Bates DW. Physician Note Composition Patterns and Time on the EHR Across Specialty Types: a National, Cross-sectional Study. Journal of general internal medicine 2022. PMID: 36418647


  21. Apathy NC, Rotenstein L, Bates DW, Holmgren AJ. Documentation dynamics: note composition, burden, and physician efficiency. Health services research 2022. PMID: 36342001


  22. Rotenstein LS, Holmgren AJ, Healey MJ, Horn DM, Ting DY, Lipsitz S, Salmasian H, Gitomer R, Bates DW. Association Between Electronic Health Record Time and Quality of Care Metrics in Primary Care. JAMA network open 2022. PMID: 36255725


  23. Rotenstein LS, Apathy NC, Bates DW, Landon B. Variation in Support for Documentation Among Primary Care Physicians by Gender. Journal of the American Board of Family Medicine : JABFM 2022. PMID: 36096659


  24. Roubinov D, Haack LM, Folk JB, Rotenstein L, Accurso EC, Dahiya P, Ponce AN, Nava V, Maldonado Y, Linos E, Mangurian C. Gender Differences in National Institutes of Health Grant Submissions Before and During the COVID-19 Pandemic. Journal of women's health (2002) 2022. PMID: 36112424


  25. Rotenstein LS, Berwick DM, Cassel CK. Addressing Well-being Throughout the Health Care Workforce: The Next Imperative. Volume 328 of Issue 6. JAMA 2022. PMID: 35849383


  26. Rotenstein LS, Melnick ER, Sinsky CA. A Learning Health System Agenda for Organizational Approaches to Enhancing Occupational Well-being Among Clinicians. Volume 327 of Issue 21. JAMA 2022. PMID: 35551325


  27. Rotenstein LS, Dadlani A, Cleary J, Sen S, Jena AB, Mata DA. Patterns in Actions Against Physician Licenses Related to Substance Use and Psychological or Physical Impairment in the US From 2004 to 2020. Volume 3 of Issue 6. JAMA health forum 2022. PMID: 35977239


  28. Holmgren AJ, Rotenstein L, Downing NL, Bates DW, Schulman K. Association between state-level malpractice environment and clinician electronic health record (EHR) time. Journal of the American Medical Informatics Association : JAMIA 2022. PMID: 35271723


  29. Rotenstein LS, Apathy N, Landon B, Bates DW. Assessment of Satisfaction With the Electronic Health Record Among Physicians in Physician-Owned vs Non-Physician-Owned Practices. Volume 5 of Issue 4. JAMA network open 2022. PMID: 35446397


  30. Rotenstein LS, Fong AS, Jeffery MM, Sinsky CA, Goldstein R, Williams B, Melnick ER. Gender Differences in Time Spent on Documentation and the Electronic Health Record in a Large Ambulatory Network. Volume 5 of Issue 3. JAMA network open 2022. PMID: 35323954


  31. Rotenstein LS, Sinsky C, Cassel CK. How to Measure Progress in Addressing Physician Well-being: Beyond Burnout. Volume 326 of Issue 21. JAMA 2021. PMID: 34757427


  32. Schmidt S, Gupta R, Bracey J, Volerman A, Henry T, Jackson C, Levine D, Jones D, Richter JM, Schmidt J, Rotenstein L, Berger Z, Peairs K, Singh H, Schwartz M, Bailey J, Goodson J. Primary Care Practice Transformation in the Era of COVID-19 and Beyond: Key Principles for General Internal Medicine Practitioners. TO REMOVE 2021. PMID: 34845581


  33. Frank E, Zhao Z, Fang Y, Rotenstein LS, Sen S, Guille C. Experiences of Work-Family Conflict and Mental Health Symptoms by Gender Among Physician Parents During the COVID-19 Pandemic. Volume 4 of Issue 11. JAMA network open 2021. PMID: 34767022


  34. Mete M, Dickman J, Rowe S, Trockel MT, Rotenstein L, Khludenev G, Marchalik D. Beyond burnout: Understanding the well-being gender gap in general surgery by examining professional fulfillment and control over schedule. Volume 223 of Issue 4. American journal of surgery 2021. PMID: 34517966


  35. Rotenstein L, Harry E, Wickner P, Gupte A, Neville BA, Lipsitz S, Cullen E, Rozenblum R, Sequist TD, Dudley J. Contributors to Gender Differences in Burnout and Professional Fulfillment: A Survey of Physician Faculty. Volume 47 of Issue 11. Joint Commission journal on quality and patient safety 2021. PMID: 34507905


  36. Rotenstein L, Melia C, Samal L, Pollack S, Yu N, Cunningham R, Price C. Development of a Primary Care Transitions Clinic in an Academic Medical Center. Volume 37 of Issue 3. Journal of general internal medicine 2021. PMID: 34327654


  37. Rotenstein LS, Holmgren AJ, Downing NL, Longhurst CA, Bates DW. Differences in Clinician Electronic Health Record Use Across Adult and Pediatric Primary Care Specialties. JAMA network open 2021. PMID: 34241631


  38. Foote MB, Jain N, Wang P, Rotenstein L, Yialamas MA, Katz JT. The Think Tank: An Organizational Framework to Enable Resident-Led Quality Improvement and Wellness Project Innovation. Volume 13 of Issue 3. Journal of graduate medical education 2021. PMID: 34178276


  39. Rotenstein LS, Holmgren AJ, Downing NL, Bates DW. Differences in Total and After-hours Electronic Health Record Time Across Ambulatory Specialties. JAMA internal medicine 2021. PMID: 33749732


  40. Rotenstein LS, Torre M, Cleary JL, Sen S, Guille C, Mata DA. Differences in Gender Representation in the Altmetric Top 100. Volume 37 of Issue 3. Journal of general internal medicine 2021. PMID: 33945112


  41. Rotenstein LS, Huckman RS, Cassel CK. Making Doctors Effective Managers and Leaders: A Matter of Health and Well-Being. Volume 96 of Issue 5. Academic medicine : journal of the Association of American Medical Colleges 2021. PMID: 33332911


  42. Rotenstein LS, Reede JY, Jena AB. Addressing Workforce Diversity - A Quality-Improvement Framework. Volume 384 of Issue 12. The New England journal of medicine 2021. PMID: 33764706


  43. Mensah M, Beeler W, Rotenstein L, Jagsi R, Spetz J, Linos E, Mangurian C. Sex Differences in Salaries of Department Chairs at Public Medical Schools. JAMA internal medicine 2020. PMID: 32119059


  44. Rotenstein LS, Zhao Z, Mata DA, Guille C, Sen S. Substantial Overlap Between Factors Predicting Symptoms of Depression and Burnout Among Medical Interns. Volume 36 of Issue 1. Journal of general internal medicine 2020. PMID: 32026254


  45. Eberly LA, Richterman A, Beckett AG, Wispelwey B, Marsh RH, Cleveland Manchanda EC, Chang CY, Glynn RJ, Brooks KC, Boxer R, Kakoza R, Goldsmith J, Loscalzo J, Morse M, Lewis EF, Abel S, Adams A, Anaya J, Andrews EH, Atkinson B, Avutu V, Bachorik A, Badri O, Bailey M, Baird K, Bakshi S, Balaban D, Barshop K, Baumrin E, Bayomy O, Beamesderfer J, Becker N, Berg DD, Berman AN, Blum SM, Boardman AP, Boden K, Bonacci RA, Brown S, Campbell K, Case S, Cetrone E, Charrow A, Chiang D, Clark D, Cohen AJ, Cooper A, Cordova T, Cuneo CN, de Feria AA, Deffenbacher K, DeFilippis EM, DeGregorio G, Deutsch AJ, Diephuis B, Divakaran S, Dorschner P, Downing N, Drescher C, D'Silva KM, Dunbar P, Duong D, Earp S, Eckhardt C, Elman SA, England R, Everett K, Fedotova N, Feingold-Link T, Ferreira M, Fisher H, Foo P, Foote M, Franco I, Gilliland T, Greb J, Greco K, Grewal S, Grin B, Growdon ME, Guercio B, Hahn CK, Hasselfeld B, Haydu EJ, Hermes Z, Hildick-Smith G, Holcomb Z, Holroyd K, Horton L, Huang G, Jablonski S, Jacobs D, Jain N, Japa S, Joseph R, Kalashnikova M, Kalwani N, Kang D, Karan A, Katz JT, Kellner D, Kidia K, Kim JH, Knowles SM, Kolbe L, Kore I, Koullias Y, Kuye I, Lang J, Lawlor M, Lechner MG, Lee K, Lee S, Lee Z, Limaye N, Lin-Beckford S, Lipsyc M, Little J, Loewenthal J, Logaraj R, Lopez DM, Loriaux D, Lu Y, Ma K, Marukian N, Matias W, Mayers JR, McConnell I, McLaughlin M, Meade C, Meador C, Mehta A, Messenger E, Michaelidis C, Mirsky J, Mitten E, Mueller A, Mullur J, Munir A, Murphy E, Nagami E, Natarajan A, Nsahlai M, Nze C, Okwara N, Olds P, Paez R, Pardo M, Patel S, Petersen A, Phelan L, Pimenta E, Pipilas D, Plovanich M, Pong D, Powers BW, Rao A, Ramirez Batlle H, Ramsis M, Reichardt A, Reiger S, Rengarajan M, Rico S, Rome BN, Rosales R, Rotenstein L, Roy A, Royston S, Rozansky H, Rudder M, Ryan CE, Salgado S, Sanchez P, Schulte J, Sekar A, Semenkovich N, Shannon E, Shaw N, Shorten AB, Shrauner W, Sinnenberg L, Smithy JW, Snyder G, Sreekrishnan A, Stabenau H, Stavrou E, Stergachis A, Stern R, Stone A, Tabrizi S, Tanyos S, Thomas C, Thun H, Torres-Lockhart K, Tran A, Treasure C, Tsai FD, Tsaur S, Tschirhart E, Tuwatananurak J, Venkateswaran RV, Vishnevetsky A, Wahl L, Wall A, Wallace F, Walsh E, Wang P, Ward HB, Warner LN, Weeks LD, Weiskopf K, Wengrod J, Williams JN, Winkler M, Wong JL, Worster D, Wright A, Wunsch C, Wynter JS, Yarbrough C, Yau WY, Yazdi D, Yeh J, Yialamas MA, Yozamp N, Zambrotta M, Zon R. Identification of Racial Inequities in Access to Specialized Inpatient Heart Failure Care at an Academic Medical Center. Circulation. Heart failure 2019. PMID: 31658831


  46. Rotenstein LS, Zhang Y, Jacobson JO. Chronic Comorbidity Among Patients With Cancer: An Impetus for Oncology and Primary Care Collaboration. Volume 5 of Issue 8. JAMA oncology 2019. PMID: 31268490


  47. Rotenstein LS, Wickner P, Hauser L, Littlefield M, Abbett S, Desrosiers J, Bates DW, Dudley J, Laskowski KR. An Academic Medical Center-Based Incubator to Promote Clinical Innovation and Financial Value. Volume 45 of Issue 4. Joint Commission journal on quality and patient safety 2019. PMID: 30665836


  48. Rotenstein L, Perez K, Wohler D, Sanders S, Im D, Kazberouk A, Phillips RS. Preparing health professions students to lead change. Volume 32 of Issue 2. Leadership in health services (Bradford, England) 2018. PMID: 30945594


  49. Rotenstein LS, Torre M, Ramos MA, Rosales RC, Guille C, Sen S, Mata DA. Prevalence of Burnout Among Physicians: A Systematic Review. Volume 320 of Issue 11. JAMA 2018. PMID: 30326495


  50. Rotenstein LS, Berman RA, Katz JT, Yialamas MA. Making the Voices of Female Trainees Heard. Annals of internal medicine 2018. PMID: 30014140


  51. Rotenstein LS, Jena AB. Lost Taussigs - The Consequences of Gender Discrimination in Medicine. Volume 378 of Issue 24. The New England journal of medicine 2018. PMID: 29897850


  52. Rotenstein LS, Dusetzina SB, Keating NL. Out-of-Pocket Spending Not Associated with Oral Oncolytic Survival Benefit. Volume 24 of Issue 6. Journal of managed care & specialty pharmacy 2018. PMID: 29799324


  53. Ganeshan S, Gheihman G, Palmor M, Choi S, Wohler D, Rotenstein LS. Shared care planning: Realizing the promise of team-based person-centered care. Volume 6 of Issue 2. Healthcare (Amsterdam, Netherlands) 2018. PMID: 29602743


  54. Rotenstein LS, Kerman AO, Killoran J, Balboni TA, Krishnan MS, Taylor A, Martin NE. Impact of a clinical pathway tool on appropriate palliative radiation therapy for bone metastases. Volume 8 of Issue 4. Practical radiation oncology 2017. PMID: 29429920


  55. Rotenstein LS, Huckman RS, Wagle NW. Making Patients and Doctors Happier - The Potential of Patient-Reported Outcomes. Volume 377 of Issue 14. The New England journal of medicine 2017. PMID: 28976860


  56. Rotenstein LS, Agarwal A, O'Neil K, Kelly A, Keaty M, Whitehouse C, Kalinowski B, Orio PF, Wagle N, Martin NE. Implementing patient-reported outcome surveys as part of routine care: lessons from an academic radiation oncology department. Volume 24 of Issue 5. Journal of the American Medical Informatics Association : JAMIA 2017. PMID: 28339771


  57. Rotenstein LS, Ramos MA, Torre M, Segal JB, Peluso MJ, Guille C, Sen S, Mata DA. Prevalence of Depression, Depressive Symptoms, and Suicidal Ideation Among Medical Students: A Systematic Review and Meta-Analysis. Volume 316 of Issue 21. TO REMOVE 2016. PMID: 27923088


  58. Rotenstein L, Tucker S, Kakoza R, Tishler L, Zai A, Wu C. The critical components of an electronic care plan tool for primary care: an exploratory qualitative study. Volume 23 of Issue 2. Journal of innovation in health informatics 2016. PMID: 27869585


  59. Rotenstein L, Nathan A, Ghobrial I, Antin J, Parnes A. Management of refractory autoimmune hemolytic anemia via allogeneic stem cell transplantation. Volume 51 of Issue 11. Bone marrow transplantation 2016. PMID: 27272445


  60. Jacobson JO, Rotenstein LS, Berry LL. New Diagnosis Bundle: Improving Care Delivery for Patients With Newly Diagnosed Cancer. Volume 12 of Issue 5. Journal of oncology practice 2016. PMID: 27048612


  61. Ramos MA, Rotenstein LS, Mata DA. Student-run free clinics: the USA's psychiatry recruitment solution? Volume 3 of Issue 4. The lancet. Psychiatry 2016. PMID: 27063382


  62. Rotenstein LS, Sheridan M, Garg R, Adler GK. Effect of mineralocorticoid receptor blockade on hippocampal-dependent memory in adults with obesity. Volume 23 of Issue 6. Obesity (Silver Spring, Md.) 2015. PMID: 25959271


  63. Juarez M, Reyes M, Coleman T, Rotenstein L, Sao S, Martinez D, Jones M, Mackelprang R, De Bellard ME. Characterization of the trunk neural crest in the bamboo shark, Chiloscyllium punctatum. Volume 521 of Issue 14. The Journal of comparative neurology 2013. PMID: 23640803


  64. Rafat M, Rotenstein LS, Hu JL, Auguste DT. Engineered endothelial cell adhesion via VCAM1 and E-selectin antibody-presenting alginate hydrogels. Volume 8 of Issue 7. Acta biomaterialia 2012. PMID: 22504076


  65. Rafat M, Rotenstein LS, You JO, Auguste DT. Dual functionalized PVA hydrogels that adhere endothelial cells synergistically. Volume 33 of Issue 15. Biomaterials 2012. PMID: 22364701


  66. Rotenstein L, Close KL. Advances in diabetes thinking: a critical summary and analysis of keystone 2009. Volume 12 of Issue 2. Diabetes technology & therapeutics 2010. PMID: 20105048


  67. Rotenstein L, Milanes A, Juarez M, Reyes M, de Bellard ME. Embryonic development of glial cells and myelin in the shark, Chiloscyllium punctatum. Volume 9 of Issue 8. Gene expression patterns : GEP 2009. PMID: 19733690


  68. Rotenstein L, Herath K, Gould RM, de Bellard ME. Characterization of the shark myelin Po protein. Volume 72 of Issue 1. Brain, behavior and evolution 2008. PMID: 18635929