Jonathan Terdiman, MD

Professor of Clinical Medicine

Dr. Jonathan P. Terdiman is a Professor of Clinical Medicine and Surgery and the Chief of the Gastroenterology Division at UCSF Health. He earned his undergraduate degree from Princeton University in 1985 and his medical degree from the Columbia University College of Physicians and Surgeons in 1989. Dr. Terdiman then completed his residency in internal medicine and fellowships in critical care medicine and gastroenterology at UCSF before joining the faculty in 1996.

Dr. Terdiman has a busy clinical practice in gastroenterology, with a focus on the management of patients with inflammatory bowel disease and those at high risk for gastrointestinal cancer. In 2012 the California Chapter of the Crohn's and Colitis Foundation of America named Dr. Terdiman as a Champion of Hope for his leadership in the care of patients with IBD. In 2013 Dr Terdiman was elected to the UCSF Department of Medicine’s Master Clinician Council, and he has been named a Bay area Top Doctor by San Francisco Magazine for the past ten years and counting. In 2022 Dr. Terdiman was honored to receive the White Helmet Award from the San Francisco Firefighters Foundation in recognition of his work in cancer prevention among firefighters. Dr. Terdiman also is a leading teacher of clinical medicine at UCSF. He has received numerous campus-wide teaching awards, and he is a past member of the Haile T Debas Academy of Medical Educators. Dr. Terdiman’s primary research activities focus on the assessment and mitigation of cancer risk among patients at high risk because of a genetic predisposition to the disease. He also is actively engaged in projects assessing the safety and efficacy of new therapies for inflammatory bowel disease.

In addition to his work at UCSF, Dr. Terdiman served on the board of trustees of the northern California chapter of the Crohn’s and Colitis Foundation of America (CCFA) for many years, and he was board president from 2010-2012. Dr. Terdiman currently is the chair of the board of trustees of the Brandeis School of San Francisco.

Education
2020 - Diversity, Equity, and Inclusion Champion Training, University of California
Fellowship, 1996 - Gastroenterology, University of California
Fellowship, 1993 - Critical Care Medicine, University of California
Residency, 1992 - Internal Medicine, University of California
MD, 1989 - Medicine, College of Physicians and Surgeons, Columbia University
Websites
Publications

  1. Ness RM, Llor X, Abbass MA, Bishu S, Chen CT, Cooper G, Early DS, Friedman M, Fudman D, Giardiello FM, Glaser K, Gurudu S, Hall M, Huang LC, Issaka R, Katona B, Kidambi T, Lazenby AJ, Maratt J, Markowitz AJ, Marsano J, May FP, Mayer RJ, Olortegui K, Patel S, Peter S, Porter LD, Shafi M, Stanich PP, Terdiman J, Vu P, Weiss JM, Wood E, Cassara CJ, Sambandam V. NCCN Guidelines® Insights: Colorectal Cancer Screening, Version 1.2024. Journal of the National Comprehensive Cancer Network : JNCCN 2024. PMID: 39236750


  2. Kidambi TD, Qadri R, Varughese J, Seto T, Idos G, Lin J, Hirsch P, Trieu H, Ma H, Hein M, Ahn A, Hy-Hincy C, Lew MW, Kessler J, Perumpail RB, Terdiman JP, Lee JK, Day L, Manesh RS, Taplitz R, Banciu-Odell C. Validation of Quality Assessment Measures for Inpatient Gastroenterology Consults on Oncologic Patients in Non-teaching Services at a Cancer Center: A Cross-Sectional Study. Digestive diseases and sciences 2024. PMID: 39068381


  3. Mennillo E, Kim YJ, Lee G, Rusu I, Patel RK, Dorman LC, Flynn E, Li S, Bain JL, Andersen C, Rao A, Tamaki S, Tsui J, Shen A, Lotstein ML, Rahim M, Naser M, Bernard-Vazquez F, Eckalbar W, Cho SJ, Beck K, El-Nachef N, Lewin S, Selvig DR, Terdiman JP, Mahadevan U, Oh DY, Fragiadakis GK, Pisco A, Combes AJ, Kattah MG. Single-cell and spatial multi-omics highlight effects of anti-integrin therapy across cellular compartments in ulcerative colitis. Nature communications 2024. PMID: 38374043


  4. Mennillo E, Kim YJ, Rusu I, Lee G, Dorman LC, Bernard-Vazquez F, Bain JL, Patel R, Andersen C, Rao A, Tamaki S, Tsui J, Shen A, Naser M, Eckalbar W, Cho SJ, Beck K, El-Nachef N, Lewin S, Selvig DR, Terdiman JP, Mahadevan U, Oh DY, Fragiadakis GK, Pisco A, Combes AJ, Kattah MG. Single-cell and spatial multi-omics identify innate and stromal modules targeted by anti-integrin therapy in ulcerative colitis. bioRxiv : the preprint server for biology 2023. PMID: 36711576


  5. Chugh R, Braga-Neto MB, Fredrick TW, Ramos GP, Terdiman J, El-Nachef N, Loftus EV, Mahadevan U, Kane SV. Multicenter Real-world Experience of Upadacitinib in the Treatment of Crohn's Disease. Journal of Crohn's & colitis 2022. PMID: 36272109


  6. Wang CW, Mclean I R, Cheng YW, Kim S, Terdiman J, Kathpalia P, Beck KR. Racial Disparities in Endoscopy Cancellations During the COVID-19 Pandemic. Digestive diseases and sciences 2022. PMID: 35732970


  7. Smith BJ, Piceno Y, Zydek M, Zhang B, Syriani LA, Terdiman JP, Kassam Z, Ma A, Lynch SV, Pollard KS, El-Nachef N. Strain-resolved analysis in a randomized trial of antibiotic pretreatment and maintenance dose delivery mode with fecal microbiota transplant for ulcerative colitis. 2022. PMID: 35365713


  8. Feuerstein JD, Ho EY, Shmidt E, Singh H, Falck-Ytter Y, Sultan S, Terdiman JP, American Gastroenterological Association Institute Clinical Guidelines Committee. AGA Clinical Practice Guidelines on the Medical Management of Moderate to Severe Luminal and Perianal Fistulizing Crohn's Disease. 2021. PMID: 34051983


  9. Ho EY, Singh S, Terdiman JP. Providing the Best Care for Patients With Crohn's Disease: An Examination of the New AGA Clinical Practice Guidelines on the Medical Management of Moderate to Severe Luminal and Perianal Fistulizing Crohn's Disease. 2021. PMID: 34051986


  10. Shmidt E, Ho EY, Feuerstein JD, Singh S, Terdiman JP. Spotlight: Medical Management of Moderate to Severe Luminal and Perianal Fistulizing Crohn's Disease. 2021. PMID: 34057068


  11. Provenzale D, Ness RM, Llor X, Weiss JM, Abbadessa B, Cooper G, Early DS, Friedman M, Giardiello FM, Glaser K, Gurudu S, Halverson AL, Issaka R, Jain R, Kanth P, Kidambi T, Lazenby AJ, Maguire L, Markowitz AJ, May FP, Mayer RJ, Mehta S, Patel S, Peter S, Stanich PP, Terdiman J, Keller J, Dwyer MA, Ogba N. NCCN Guidelines Insights: Colorectal Cancer Screening, Version 2.2020. Journal of the National Comprehensive Cancer Network : JNCCN 2020. PMID: 33022639


  12. Kotwani P, Terdiman J, Lewin S. Tofacitinib for rescue therapy in acute severe ulcerative colitis: a real-world experience. Journal of Crohn's & colitis 2020. PMID: 32020189


  13. Lee JK, Kidambi TD, Kaltenbach T, Bhat YM, Shergill A, McQuaid KR, Terdiman JP, Soetikno RM. Impact of observational training on endoscopic mucosal resection outcomes and competency for large colorectal polyps: single endoscopist experience. Endoscopy international open 2020. PMID: 32140557


  14. Singh S, Allegretti JR, Siddique SM, Terdiman JP. AGA Technical Review on the Management of Moderate to Severe Ulcerative Colitis. Gastroenterology 2020. PMID: 31945351


  15. Selvig D, Piceno Y, Terdiman J, Zydek M, Umetsu SE, Balitzer D, Fadrosh D, Lynch K, Lamere B, Leith T, Kassam Z, Beck K, Lewin S, Ma A, Somsouk M, Lynch SV, El-Nachef N. Fecal Microbiota Transplantation in Pouchitis: Clinical, Endoscopic, Histologic, and Microbiota Results from a Pilot Study. Digestive diseases and sciences 2019. PMID: 31302808


  16. Gutin L, Piceno Y, Fadrosh D, Lynch K, Zydek M, Kassam Z, LaMere B, Terdiman J, Ma A, Somsouk M, Lynch S, El-Nachef N. Fecal microbiota transplant for Crohn disease: A study evaluating safety, efficacy, and microbiome profile. United European gastroenterology journal 2019. PMID: 31316785


  17. Adler E, Tabaa A, Kassam Z, Zydek M, Terdiman J, El-Nachef N. Capsule-Delivered Fecal Microbiota Transplant Is Safe and Well Tolerated in Patients with Ulcerative Colitis. Digestive diseases and sciences 2019. PMID: 30919208


  18. Mao EJ, Lewin S, Terdiman JP, Beck K. Safety of dual biological therapy in Crohn's disease: a case series of vedolizumab in combination with other biologics. BMJ open gastroenterology 2018. PMID: 30538822


  19. Kidambi TD, Terdiman JP, Lee JK. Negative withdrawal time: simple and efficient. Gastrointestinal endoscopy 2018. PMID: 30217248


  20. Kidambi TD, Terdiman JP, El-Nachef N, Singh A, Kattah MG, Lee JK. Effect of I-scan Electronic Chromoendoscopy on Detection of Adenomas During Colonoscopy. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2018. PMID: 29935326


  21. Kidambi TD, Goldberg D, Nussbaum R, Blanco A, Umetsu SE, Terdiman JP, Lee JK. Novel variant of unknown significance in MUTYH in a patient with MUTYH-associated polyposis: a case to reclassify. Clinical journal of gastroenterology 2018. PMID: 29766397


  22. Gray PN, Tsai P, Chen D, Wu S, Hoo J, Mu W, Li B, Vuong H, Lu HM, Batth N, Willett S, Uyeda L, Shah S, Gau CL, Umali M, Espenschied C, Janicek M, Brown S, Margileth D, Dobrea L, Wagman L, Rana H, Hall MJ, Ross T, Terdiman J, Cullinane C, Ries S, Totten E, Elliott AM. TumorNext-Lynch-MMR: a comprehensive next generation sequencing assay for the detection of germline and somatic mutations in genes associated with mismatch repair deficiency and Lynch syndrome. Oncotarget 2018. PMID: 29755653


  23. Kidambi TD, Pedley C, Blanco A, Bergsland EK, Terdiman JP. Lower gastrointestinal neuroendocrine neoplasms associated with hereditary cancer syndromes: a case series. Familial cancer 2017. PMID: 28283864


  24. Kidambi TD, Schmajuk G, Gross AJ, Ostroff JW, Terdiman JP, Lee JK. Endoscopy is of low yield in the identification of gastrointestinal neoplasia in patients with dermatomyositis: A cross-sectional study. World journal of gastroenterology 2017. PMID: 28765700


  25. Azofra AS, Kidambi TD, Jeremy RJ, Conrad P, Blanco A, Myers M, Barkovich J, Terdiman JP. Differences in neuropsychological and behavioral parameters and brain structure in patients with familial adenomatous polyposis: a sibling-paired study. Hereditary cancer in clinical practice 2016. PMID: 27777639


  26. Kidambi TD, Lee R, Terdiman JP, Day L. Successful implementation of Lynch syndrome screening in a safety net institution. Journal of community genetics 2016. PMID: 27372833


  27. Kidambi TD, Blanco A, Van Ziffle J, Terdiman JP. Constitutional MLH1 methylation presenting with colonic polyposis syndrome and not Lynch syndrome. Familial cancer 2016. PMID: 26781822


  28. Guindalini RS, Win AK, Gulden C, Lindor NM, Newcomb PA, Haile RW, Raymond V, Stoffel E, Hall M, Llor X, Ukaegbu CI, Solomon I, Weitzel J, Kalady M, Blanco A, Terdiman J, Shuttlesworth GA, Lynch PM, Hampel H, Lynch HT, Jenkins MA, Olopade OI, Kupfer SS. Mutation spectrum and risk of colorectal cancer in African American families with Lynch syndrome. Gastroenterology 2015. PMID: 26248088


  29. Ho CK, Boscardin CK, Gleason N, Collado D, Terdiman J, Terrault NA, Gonzales R. Optimizing the pre-referral workup for gastroenterology and hepatology specialty care: consensus using the Delphi method. Journal of evaluation in clinical practice 2015. PMID: 26223584


  30. Goodenberger ML, Thomas BC, Riegert-Johnson D, Boland CR, Plon SE, Clendenning M, Win AK, Senter L, Lipkin SM, Stadler ZK, Macrae FA, Lynch HT, Weitzel JN, de la Chapelle A, Syngal S, Lynch P, Parry S, Jenkins MA, Gallinger S, Holter S, Aronson M, Newcomb PA, Burnett T, Le Marchand L, Pichurin P, Hampel H, Terdiman JP, Lu KH, Thibodeau S, Lindor NM. PMS2 monoallelic mutation carriers: the known unknown. Genetics in medicine : official journal of the American College of Medical Genetics 2015. PMID: 25856668


  31. Kidambi TD, Terdiman JP. Screening for Lynch syndrome: it is time to shift the focus. Digestive diseases and sciences 2015. PMID: 25563721


  32. Lee JK, Terdiman JP, Corley DA. Multitarget stool DNA testing for colorectal-cancer screening. The New England journal of medicine 2014. PMID: 25006739


  33. Kidambi TD, Blanco A, Myers M, Conrad P, Loranger K, Terdiman JP. Selective Versus Universal Screening for Lynch Syndrome: A Six-Year Clinical Experience. Digestive diseases and sciences 2014. PMID: 24903654


  34. Walsh JM, Potter MB, Arora M, Gildegorin G, Terdiman J. A workplace colorectal cancer screening program in firefighters: lessons learned. Occupational medicine (Oxford, England) 2014. PMID: 24744344


  35. Shah S, Terdiman J, Gundling K, Mahadevan U. Immunoglobulin therapy for refractory Crohn's disease. Therapeutic advances in gastroenterology 2014. PMID: 24587823


  36. Terdiman JP, Gruss CB, Heidelbaugh JJ, Sultan S, Falck-Ytter YT. American Gastroenterological Association Institute guideline on the use of thiopurines, methotrexate, and anti-TNF-a biologic drugs for the induction and maintenance of remission in inflammatory Crohn's disease. Gastroenterology 2013. PMID: 24267474


  37. Burt RW, Cannon JA, David DS, Early DS, Ford JM, Giardiello FM, Halverson AL, Hamilton SR, Hampel H, Ismail MK, Jasperson K, Klapman JB, Lazenby AJ, Lynch PM, Mayer RJ, Ness RM, Provenzale D, Rao MS, Shike M, Steinbach G, Terdiman JP, Weinberg D, Dwyer M, Freedman-Cass D, National comprehensive cancer network. Colorectal cancer screening. 2013. PMID: 24335688


  38. Truta B, Li DX, Mahadevan U, Fisher ER, Chen YY, Grace K, Velayos F, Terdiman JP. Serologic markers associated with development of Crohn's disease after ileal pouch anal anastomosis for ulcerative colitis. Digestive diseases and sciences 2013. PMID: 24091907


  39. Yurgelun MB, Mercado R, Rosenblatt M, Dandapani M, Kohlmann W, Conrad P, Blanco A, Shannon KM, Chung DC, Terdiman J, Gruber SB, Garber JE, Syngal S, Stoffel EM. Impact of genetic testing on endometrial cancer risk-reducing practices in women at risk for Lynch syndrome. Gynecologic oncology 2012. PMID: 22940489


  40. Kuppermann M, Wang G, Wong S, Blanco A, Conrad P, Nakagawa S, Terdiman J, Ladabaum U. Preferences for outcomes associated with decisions to undergo or forgo genetic testing for Lynch syndrome. Cancer 2012. PMID: 22786716


  41. Katz L, Gisbert JP, Manoogian B, Lin K, Steenholdt C, Mantzaris GJ, Atreja A, Ron Y, Swaminath A, Shah S, Hart A, Lakatos PL, Ellul P, Israeli E, Svendsen MN, van der Woude CJ, Katsanos KH, Yun L, Tsianos EV, Nathan T, Abreu M, Dotan I, Lashner B, Brynskov J, Terdiman JP, Higgins PD, Chaparro M, Ben-Horin S. Doubling the infliximab dose versus halving the infusion intervals in Crohn's disease patients with loss of response. Inflammatory bowel diseases 2012. PMID: 22294554


  42. Larsen M, Hills N, Terdiman J. The impact of the quality of colon preparation on follow-up colonoscopy recommendations. The American journal of gastroenterology 2011. PMID: 22138933


  43. Lin KK, Velayos F, Fisher E, Terdiman JP. Durability of infliximab dose intensification in Crohn's disease. Digestive diseases and sciences 2011. PMID: 22089254


  44. Ladabaum U, Wang G, Terdiman J, Blanco A, Kuppermann M, Boland CR, Ford J, Elkin E, Phillips KA. Strategies to identify the Lynch syndrome among patients with colorectal cancer: a cost-effectiveness analysis. Volume 155 of Issue 2. Annals of internal medicine 2011. PMID: 21768580


  45. Khan O, Blanco A, Conrad P, Gulden C, Moss TZ, Olopade OI, Kupfer SS, Terdiman J. Performance of Lynch syndrome predictive models in a multi-center US referral population. The American journal of gastroenterology 2011. PMID: 21747416


  46. Terdiman JP. The prevention of colitis-related cancer by 5-aminosalicylates: an appealing hypothesis that remains unproven. The American journal of gastroenterology 2011. PMID: 21468069


  47. Day LW, Espey DK, Madden E, Segal M, Terdiman JP. Screening prevalence and incidence of colorectal cancer among American Indian/Alaskan natives in the Indian Health Service. Digestive diseases and sciences 2011. PMID: 21234688


  48. Terdiman JP, McQuaid KR. Surveillance guidelines should be updated to recognize the importance of serrated polyps. Volume 139 of Issue 5. Gastroenterology 2010. PMID: 20875785


  49. El-Nachef N, Terdiman J, Mahadevan U. Anti-tumor necrosis factor therapy for inflammatory bowel disease in the setting of immunosuppression for solid organ transplantation. The American journal of gastroenterology 2010. PMID: 20445523


  50. Stoffel EM, Mercado RC, Kohlmann W, Ford B, Grover S, Conrad P, Blanco A, Shannon KM, Powell M, Chung DC, Terdiman J, Gruber SB, Syngal S. Prevalence and predictors of appropriate colorectal cancer surveillance in Lynch syndrome. The American journal of gastroenterology 2010. PMID: 20354509


  51. Burt RW, Barthel JS, Dunn KB, David DS, Drelichman E, Ford JM, Giardiello FM, Gruber SB, Halverson AL, Hamilton SR, Ismail MK, Jasperson K, Lazenby AJ, Lynch PM, Martin EW, Mayer RJ, Ness RM, Provenzale D, Rao MS, Shike M, Steinbach G, Terdiman JP, Weinberg D. NCCN clinical practice guidelines in oncology. Colorectal cancer screening. Journal of the National Comprehensive Cancer Network : JNCCN 2010. PMID: 20064289


  52. Terdiman JP, Johnson LK, Kim YS, Sleisenger MH, Gum JR, Hayes A, Weinberg VK, McQuaid KR. Chemoprevention of colonic polyps with balsalazide: an exploratory, double-blind, placebo-controlled study. Volume 54 of Issue 11. Digestive diseases and sciences 2009. PMID: 19757048


  53. Terdiman JP. MYH-associated disease: attenuated adenomatous polyposis of the colon is only part of the story. Gastroenterology 2009. PMID: 19879216


  54. Grover S, Stoffel EM, Mercado RC, Ford BM, Kohlman WK, Shannon KM, Conrad PG, Blanco AM, Terdiman JP, Gruber SB, Chung DC, Syngal S. Colorectal cancer risk perception on the basis of genetic test results in individuals at risk for Lynch syndrome. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009. PMID: 19620492


  55. Nguyen SP, Bent S, Chen YH, Terdiman JP. Gender as a risk factor for advanced neoplasia and colorectal cancer: a systematic review and meta-analysis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2009. PMID: 19514116


  56. Wang JY, Terdiman JP, Vittinghoff E, Minichiello T, Varma MG. Hospitalized ulcerative colitis patients have an elevated risk of thromboembolic events. Volume 15 of Issue 8. World journal of gastroenterology 2009. PMID: 19248191


  57. Li D, Jin C, McCulloch C, Kakar S, Berger BM, Imperiale TF, Terdiman JP. Association of large serrated polyps with synchronous advanced colorectal neoplasia. The American journal of gastroenterology 2009. PMID: 19223889


  58. Terdiman JP. Oncology training for the gastroenterologist: a test-case for subspecialization in gastroenterology? Gastroenterology 2008. PMID: 18775428


  59. Shergill AK, Terdiman JP. The early use of immunosuppression reduces morbidity in patients with moderately severe or severe Crohn's disease. Volume 135 of Issue 4. Gastroenterology 2008. PMID: 18773903


  60. Li D, Terdiman JP. "Did you check my colon for flat polyps?" Should patients and colonoscopists really be concerned? Gastroenterology 2008. PMID: 18541152


  61. Shergill AK, Terdiman JP. Controversies in the treatment of Crohn's disease: the case for an accelerated step-up treatment approach. Volume 14 of Issue 17. World journal of gastroenterology 2008. PMID: 18461652


  62. Truta B, Chen YY, Blanco AM, Deng G, Conrad PG, Kim YH, Park ET, Kakar S, Kim YS, Velayos F, Sleisenger MH, Terdiman JP. Tumor histology helps to identify Lynch syndrome among colorectal cancer patients. Familial cancer 2008. PMID: 18283560


  63. Stoffel EM, Ford B, Mercado RC, Punglia D, Kohlmann W, Conrad P, Blanco A, Shannon KM, Powell M, Gruber SB, Terdiman J, Chung DC, Syngal S. Sharing genetic test results in Lynch syndrome: communication with close and distant relatives. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2008. PMID: 18258490


  64. Terdiman JP. Hereditary diffuse gastric cancer: surveillance endoscopy is not enough to save lives. Gastroenterology 2007. PMID: 17983818


  65. Terdiman JP. Prevention of postoperative recurrence in Crohn's disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2007. PMID: 17967564


  66. Shergill AK, Terdiman JP. Refining colorectal cancer screening recommendations based on gender. Volume 132 of Issue 7. Gastroenterology 2007. PMID: 17570233


  67. Terdiman JP, Steinbuch M, Blumentals WA, Ullman TA, Rubin DT. 5-Aminosalicylic acid therapy and the risk of colorectal cancer among patients with inflammatory bowel disease. Inflammatory bowel diseases 2007. PMID: 17206695


  68. Shergill AK, Terdiman JP. Screening colonoscopy: the benefits are durable, but are they as great as we thought? Volume 131 of Issue 6. Gastroenterology 2006. PMID: 17188965


  69. Trautmann K, Terdiman JP, French AJ, Roydasgupta R, Sein N, Kakar S, Fridlyand J, Snijders AM, Albertson DG, Thibodeau SN, Waldman FM. Chromosomal instability in microsatellite-unstable and stable colon cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 2006. PMID: 17085649


  70. Terdiman JP. Ulcerative colitis patients with dysplastic polyps should be advised to undergo colectomy. Inflammatory bowel diseases 2006. PMID: 16954810


  71. Yang K, Allen B, Conrad P, Powell CB, Terdiman J, Chen LM. Awareness of gynecologic surveillance in women from hereditary non-polyposis colorectal cancer families. Familial cancer 2006. PMID: 16937235


  72. Inadomi JM, Terdiman J. Exploring utilities and outcomes with infliximab therapy. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2006. PMID: 16880119


  73. Deng G, Nguyen A, Tanaka H, Matsuzaki K, Bell I, Mehta KR, Terdiman JP, Waldman FM, Kakar S, Gum J, Crawley S, Sleisenger MH, Kim YS. Regional hypermethylation and global hypomethylation are associated with altered chromatin conformation and histone acetylation in colorectal cancer. International journal of cancer 2006. PMID: 16425274


  74. Levin B, Barthel JS, Burt RW, David DS, Ford JM, Giardiello FM, Gruber SB, Halverson AL, Hamilton S, Kohlmann W, Ludwig KA, Lynch PM, Marino C, Martin EW, Mayer RJ, Pasche B, Pirruccello SJ, Rajput A, Rao MS, Shike M, Steinbach G, Terdiman JP, Weinberg D, Winawer SJ. Colorectal Cancer Screening Clinical Practice Guidelines. Journal of the National Comprehensive Cancer Network : JNCCN 2006. PMID: 16569391


  75. Terdiman JP. Embarrassment is a major barrier to colon cancer prevention, especially among women: a call to action. Gastroenterology 2006. PMID: 16618431


  76. Walsh JM, Salazar R, Terdiman JP, Gildengorin G, Pérez-Stable EJ. Promoting use of colorectal cancer screening tests. Can we change physician behavior? Journal of general internal medicine 2005. PMID: 16423097


  77. Terdiman JP. Colonoscopy is superior to flexible sigmoidoscopy for colorectal cancer screening: now beyond a reasonable doubt? Gastroenterology 2005. PMID: 16285977


  78. Terdiman JP. It is time to get serious about diagnosing Lynch syndrome (hereditary nonpolyposis colorectal cancer with defective DNA mismatch repair) in the general population. Gastroenterology 2005. PMID: 16083727


  79. Young Y, Terdiman JP. Endoscopic management of familial colonic neoplasia. Gastrointestinal endoscopy clinics of North America 2005. PMID: 15990057


  80. Vesga L, Terdiman JP, Mahadevan U. Adalimumab use in pregnancy. Gut 2005. PMID: 15888806


  81. Velayos FS, Terdiman JP, Walsh JM. Effect of 5-aminosalicylate use on colorectal cancer and dysplasia risk: a systematic review and metaanalysis of observational studies. The American journal of gastroenterology 2005. PMID: 15929768


  82. Velayos FS, Allen BA, Conrad PG, Gum J, Kakar S, Chung DC, Truta B, Sleisenger MH, Kim YS, Terdiman JP. Low rate of microsatellite instability in young patients with adenomas: reassessing the Bethesda guidelines. The American journal of gastroenterology 2005. PMID: 15842591


  83. Lindor NM, Rabe K, Petersen GM, Haile R, Casey G, Baron J, Gallinger S, Bapat B, Aronson M, Hopper J, Jass J, LeMarchand L, Grove J, Potter J, Newcomb P, Terdiman JP, Conrad P, Moslein G, Goldberg R, Ziogas A, Anton-Culver H, de Andrade M, Siegmund K, Thibodeau SN, Boardman LA, Seminara D. Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency: familial colorectal cancer type X. JAMA 2005. PMID: 15855431


  84. Terdiman JP. Colorectal cancer at a young age. Gastroenterology 2005. PMID: 15825087


  85. Mahadevan U, Terdiman JP, Aron J, Jacobsohn S, Turek P. Infliximab and semen quality in men with inflammatory bowel disease. Inflammatory bowel diseases 2005. PMID: 15803031


  86. Mahadevan U, Kane S, Sandborn WJ, Cohen RD, Hanson K, Terdiman JP, Binion DG. Intentional infliximab use during pregnancy for induction or maintenance of remission in Crohn's disease. Alimentary pharmacology & therapeutics 2005. PMID: 15771759


  87. Mehta KR, Nakao K, Zuraek MB, Ruan DT, Bergsland EK, Venook AP, Moore DH, Tokuyasu TA, Jain AN, Warren RS, Terdiman JP, Waldman FM. Fractional genomic alteration detected by array-based comparative genomic hybridization independently predicts survival after hepatic resection for metastatic colorectal cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 2005. PMID: 15756001


  88. Lu KH, Dinh M, Kohlmann W, Watson P, Green J, Syngal S, Bandipalliam P, Chen LM, Allen B, Conrad P, Terdiman J, Sun C, Daniels M, Burke T, Gershenson DM, Lynch H, Lynch P, Broaddus RR. Gynecologic cancer as a "sentinel cancer" for women with hereditary nonpolyposis colorectal cancer syndrome. Obstetrics and gynecology 2005. PMID: 15738026


  89. Velayos FS, Lee SH, Qiu H, Dykes S, Yiu R, Terdiman JP, Garcia-Aguilar J. The mechanism of microsatellite instability is different in synchronous and metachronous colorectal cancer. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2005. PMID: 15749592


  90. Truta B, Allen BA, Conrad PG, Weinberg V, Miller GA, Pomponio R, Lipton LR, Guerra G, Tomlinson IP, Sleisenger MH, Kim YS, Terdiman JP. A comparison of the phenotype and genotype in adenomatous polyposis patients with and without a family history. Familial cancer 2005. PMID: 15951963


  91. Velayos FS, Williamson A, Sousa KH, Lung E, Bostrom A, Weber EJ, Ostroff JW, Terdiman JP. Early predictors of severe lower gastrointestinal bleeding and adverse outcomes: a prospective study. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2004. PMID: 15181617


  92. Nakao K, Mehta KR, Fridlyand J, Moore DH, Jain AN, Lafuente A, Wiencke JW, Terdiman JP, Waldman FM. High-resolution analysis of DNA copy number alterations in colorectal cancer by array-based comparative genomic hybridization. Carcinogenesis 2004. PMID: 15001537


  93. Umar A, Boland CR, Terdiman JP, Syngal S, de la Chapelle A, Rüschoff J, Fishel R, Lindor NM, Burgart LJ, Hamelin R, Hamilton SR, Hiatt RA, Jass J, Lindblom A, Lynch HT, Peltomaki P, Ramsey SD, Rodriguez-Bigas MA, Vasen HF, Hawk ET, Barrett JC, Freedman AN, Srivastava S. Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. Journal of the National Cancer Institute 2004. PMID: 14970275


  94. Deng G, Bell I, Crawley S, Gum J, Terdiman JP, Allen BA, Truta B, Sleisenger MH, Kim YS. BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 2004. PMID: 14734469


  95. Mathy C, Schneider K, Chen YY, Varma M, Terdiman JP, Mahadevan U. Gross versus microscopic pancolitis and the occurrence of neoplasia in ulcerative colitis. Inflammatory bowel diseases 2003. PMID: 14671483


  96. Hiramoto JS, Terdiman JP, Norton JA. Evidence-based analysis: postoperative gastric bleeding: etiology and prevention. Surgical oncology 2003. PMID: 12689666


  97. Terdiman JP. Aspirin curbs colon polyps. But for many, bleeding risks may offset benefits. Health news (Waltham, Mass.) 2003. PMID: 12739451


  98. Allen BA, Terdiman JP. Hereditary polyposis syndromes and hereditary non-polyposis colorectal cancer. Best practice & research. Clinical gastroenterology 2003. PMID: 12676117


  99. Walsh JM, Terdiman JP. Colorectal cancer screening: clinical applications. JAMA 2003. PMID: 12633192


  100. Walsh JM, Terdiman JP. Colorectal cancer screening: scientific review. JAMA 2003. PMID: 12633191


  101. Truta B, Allen BA, Conrad PG, Kim YS, Berk T, Gallinger S, Bapat B, Terdiman JP, Sleisenger MH. Genotype and phenotype of patients with both familial adenomatous polyposis and thyroid carcinoma. Familial cancer 2003. PMID: 14574158


  102. Reyes CM, Allen BA, Terdiman JP, Wilson LS. Comparison of selection strategies for genetic testing of patients with hereditary nonpolyposis colorectal carcinoma: effectiveness and cost-effectiveness. Cancer 2002. PMID: 12404277


  103. Terdiman JP, Aust DE, Chang CG, Willenbucher RF, Baretton GB, Waldman FM. High resolution analysis of chromosome 18 alterations in ulcerative colitis-related colorectal cancer. Cancer genetics and cytogenetics 2002. PMID: 12237237


  104. Terdiman JP, Levin TR, Allen BA, Gum JR, Fishbach A, Conrad PG, Miller GA, Weinberg V, Bachman R, Bergoffen J, Stembridge A, Toribara NW, Sleisenger MH, Kim YS. Hereditary nonpolyposis colorectal cancer in young colorectal cancer patients: high-risk clinic versus population-based registry. Gastroenterology 2002. PMID: 11910346


  105. Aust DE, Terdiman JP, Willenbucher RF, Chang CG, Molinaro-Clark A, Baretton GB, Loehrs U, Waldman FM. The APC/beta-catenin pathway in ulcerative colitis-related colorectal carcinomas: a mutational analysis. Cancer 2002. PMID: 11920497


  106. Deng G, Peng E, Gum J, Terdiman J, Sleisenger M, Kim YS. Methylation of hMLH1 promoter correlates with the gene silencing with a region-specific manner in colorectal cancer. British journal of cancer 2002. PMID: 11870540


  107. Terdiman JP. Colonoscopic management of lower gastrointestinal hemorrhage. Current gastroenterology reports 2001. PMID: 11560802


  108. Terdiman JP. HNPCC: an uncommon but important diagnosis. Gastroenterology 2001. PMID: 11606514


  109. Terdiman J, Gum Jr J, Conrad P, Miller G, Weinberg V, Crawley S, Levin T, Reeves C, Schmitt A, Hepburn M, Sleisenger M, Kim Y. [Search for microsatellite instability in colorectal cancer: an effective way to detect HNPCC?]. Gastroenterologie clinique et biologique 2001. PMID: 11852407


  110. Aust DE, Terdiman JP, Willenbucher RF, Chew K, Ferrell L, Florendo C, Molinaro-Clark A, Baretton GB, Löhrs U, Waldman FM. Altered distribution of beta-catenin, and its binding proteins E-cadherin and APC, in ulcerative colitis-related colorectal cancers. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2001. PMID: 11211307


  111. Terdiman JP, Gum JR, Conrad PG, Miller GA, Weinberg V, Crawley SC, Levin TR, Reeves C, Schmitt A, Hepburn M, Sleisenger MH, Kim YS. Efficient detection of hereditary nonpolyposis colorectal cancer gene carriers by screening for tumor microsatellite instability before germline genetic testing. Gastroenterology 2001. PMID: 11208710


  112. Terdiman JP. Genomic events in the adenoma to carcinoma sequence. Seminars in gastrointestinal disease 2000. PMID: 11057947


  113. Aust DE, Willenbucher RF, Terdiman JP, Ferrell LD, Chang CG, Moore DH, Molinaro-Clark A, Baretton GB, Loehrs U, Waldman FM. Chromosomal alterations in ulcerative colitis-related and sporadic colorectal cancers by comparative genomic hybridization. Human pathology 2000. PMID: 10665921


  114. Terdiman JP, Conrad PG, Sleisenger MH. Genetic testing in hereditary colorectal cancer: indications and procedures. The American journal of gastroenterology 1999. PMID: 10483990


  115. Terdiman JP. Update on upper gastrointestinal bleeding. Basing treatment decisions on patients' risk level. Postgraduate medicine 1998. PMID: 9633542


  116. Terdiman JP, Ostroff JW. Gastrointestinal bleeding in the hospitalized patient: a case-control study to assess risk factors, causes, and outcome. The American journal of medicine 1998. PMID: 9576408


  117. Terdiman JP, Ostroff JW. Risk of persistent or recurrent and intractable upper gastrointestinal bleeding in the era of therapeutic endoscopy. The American journal of gastroenterology 1997. PMID: 9382041


  118. Terdiman JP. The importance of accurate diagnosis and vigorous care of the patient with liver disease and gastrointestinal hemorrhage. Seminars in gastrointestinal disease 1997. PMID: 9360281


  119. Terdiman JP, Linker CA, Ries CA, Damon LE, Rugo HS, Ostroff JW. The role of endoscopic evaluation in patients with suspected intestinal graft-versus-host disease after allogeneic bone-marrow transplantation. Endoscopy 1996. PMID: 8934085