Jackie DesJardin, MD, MAS

HS Asst Clinical Professor

Dr. DesJardin is a cardiologist who specializes in heart failure, mechanical circulatory support, heart transplantation, and pulmonary hypertension. She is clinically skilled in evaluating and treating patients with varying degrees of heart failure and pulmonary hypertension.

As a clinician-researcher, Dr. DesJardin focuses her area of study on pulmonary hypertension and heart failure, with a specific focus on improving diagnosis and treatment of these conditions.

Education
Fellowship, 2024 - Advanced Heart Failure, University of California
MAS, 2024 - Clinical Research, University of California
Fellowship, 2023 - Cardiology, University of California
Residency, 2020 - Internal Medicine, University of California
MD, 2017 - , University of California
Publications

  1. DesJardin JT, Broerman M, Saul M, Haskett D, Nouraie SM, Simon MA. Pulmonary artery compliance is associated with mortality but lacks predictive utility. JHLT open 2026. PMID: 42027719


  2. Matusov Y, Kolaitis NA, Geft D, DesJardin J, Barnett C, Hage A, De Marco T, Lewis MI. Response. Chest 2026. PMID: 41813311


  3. Geft D, Matusov Y, Kolaitis N, DesJardin J, Barnett C, Hage A, De Marco T, Lewis MI. Response. Chest 2026. PMID: 41672669


  4. Wu Y, Baudart S, Cheng R, Kallianos K, Ruaysungnoen R, DesJardin J, Aras M, Soni K, Fiedler A, Smith J, Klein L. Percutaneous management and outcomes of outflow graft obstruction in patients with left ventricular assist device: A single-center experience. JHLT open 2025. PMID: 41541418


  5. Prabhakar A, De Bie EM, DesJardin JT, Ghatpande P, Gräf S, Howard LS, Wort SJ, Church C, Kiely DG, Sumpena E, Aung T, Carter S, Kukreja J, Hays S, Greenland JR, Singer JP, Wax M, Wolters PJ, Simon MA, Toshner M, Lagna G, Hata A. GDF15 is a putative biomarker for distinguishing pulmonary veno-occlusive disease and pulmonary arterial hypertension. The Journal of clinical investigation 2025. PMID: 41264364


  6. Jacqueline DesJardin, Jasleen Minhas, Navneet Singh, Teresa De Marco. Getting Started Early in Your Pulmonary Hypertension Career Advanced in Pulmonary Hypertension 2025. PMID:


  7. Matusov Y, Kolaitis NA, Geft D, DesJardin J, Barnett C, Hage A, De Marco T, Lewis MI. How I do it: Best practices for right heart catheterization in the diagnosis of pulmonary hypertension. Chest 2025. PMID: 40383185


  8. Haghighat L, Kalantarian S, DesJardin JT, Pellegrini CN. Evaluating Pregnancy Safety During Cardiology Training. JAMA cardiology 2024. PMID: 39110472


  9. Jheng JR, DesJardin JT, Chen YY, Huot JR, Bai Y, Cook T, Hibbard LM, Rupp JM, Fisher A, Zhang Y, Duarte JD, Desai AA, Machado RF, Simon MA, Lai YC. Plasma Proteomics Identifies B2M as a Regulator of Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction. Arteriosclerosis, thrombosis, and vascular biology 2024. PMID: 38813697


  10. DesJardin JT, Kime N, Kolaitis NA, Kronmal RA, Lammi MR, Mathai SC, Ventetuolo CE, De Marco T, PHAR Investigators. Investigating the "sex paradox" in pulmonary arterial hypertension: results from the Pulmonary Hypertension Association Registry (PHAR). The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2024. PMID: 38360160


  11. Krishnan M, Desjardin JT, Vaidya A, DE Marco T. Reproductive Care in Pulmonary Arterial Hypertension. Volume 29 of Issue 9. Journal of cardiac failure 2023. PMID: 37709384


  12. Chang LL, DesJardin JT, Albert MA, Ezekowitz J, Yusuf S. Dietary Sodium Restriction in Patients with Heart Failure. The New England journal of medicine 2023. PMID: 37099346


  13. Olson EM, Sanborn DM, Dyster TG, Kelm DJ, Murray SG, Santhosh L, DesJardin JT. Gender Disparities in Critical Care Procedure Training of Internal Medicine Residents. ATS Scholar 2023. PMID: 37538076


  14. DesJardin JT, Svetlichnaya Y, Kolaitis NA, Hays SR, Kukreja J, Schiller NB, Zier LS, Singer JP, De Marco T. Echocardiographic estimation of pulmonary vascular resistance in advanced lung disease. Pulmonary circulation 2023. PMID: 36618711


  15. DesJardin JT, Chikwe J, Hahn RT, Hung JW, Delling FN. Sex Differences and Similarities in Valvular Heart Disease. 2022. PMID: 35175844


  16. DesJardin JT, Teerlink JR. Inotropic therapies in heart failure and cardiogenic shock: an educational review. European heart journal. Acute cardiovascular care 2021. PMID: 34219157


  17. DesJardin J, Leyde S, Davis J. Weathering the perfect storm: management of heart failure in patients with substance use disorders. Volume 107 of Issue 16. Heart (British Cardiac Society) 2021. PMID: 34031158


  18. Wang TY, DesJardin JT. Time to End "Manels" in Clinical Trial Leadership. Volume 180 of Issue 10. JAMA internal medicine 2020. PMID: 32865542


  19. DesJardin JT, Healy MJ, Nah G, Vittinghoff E, Agarwal A, Marcus GM, Velez JMG, Tseng ZH, Parikh NI. Placental Abruption as a Risk Factor for Heart Failure. The American journal of cardiology 2020. PMID: 32718545


  20. DesJardin JT, Kolaitis NA, Kime N, Kronmal RA, Benza RL, Elwing JM, Lammi MR, McConnell JW, Presberg KW, Sager JS, Shlobin OA, De Marco T. Age-related differences in hemodynamics and functional status in pulmonary arterial hypertension: Baseline results from the Pulmonary Hypertension Association Registry. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2020. PMID: 32507341


  21. DesJardin JT, Manicardi M, Svetlichnaya Y, Kolaitis NA, Papolos AI, Selby VN, Zier LS, Klein L, Aras MA, Yao FY, Roberts JP, De Marco T. Non-Invasive Estimation of Pulmonary Vascular Resistance Improves Portopulmonary Hypertension Screening in Liver Transplant Candidates. Clinical transplantation 2019. PMID: 31074522


  22. DesJardin JT, Zier LS. Successful Use of Pulmonary Vasodilators in Acute Chest Syndrome Complicated by Persistent Right Ventricular Failure. Case reports in cardiology 2019. PMID: 31149361


  23. DesJardin JT, Ricceri SK, Brown SD, Webb EM, Naeger DM, Teismann NA.. A Near-Peer Point-of-Care Ultrasound Elective for Medical Students: Impact on Anatomy Knowledge, Perceptions about Ultrasound, and Self-Reported Skill Level Academic radiology 2017. PMID:


  24. Forcelli PA, DesJardin JT, West EA, Holmes AL, Elorette C, Wellman LL, Malkova L. Amygdala selectively modulates defensive responses evoked from the superior colliculus in non-human primates. Volume 11 of Issue 12. Social cognitive and affective neuroscience 2016. PMID: 27510499


  25. Forcelli PA, Palchik G, Leath T, DesJardin JT, Gale K, Malkova L. Memory loss in a nonnavigational spatial task after hippocampal inactivation in monkeys. Volume 111 of Issue 11. Proceedings of the National Academy of Sciences of the United States of America 2014. PMID: 24591610


  26. Desjardin JT, Becerra SP, Subramanian P. Searching for Alternatively Spliced Variants of Phospholipase Domain-Containing 2 (Pnpla2), a Novel Gene in the Retina. Volume 4 of Issue 5. Journal of clinical & experimental ophthalmology 2013. PMID: 24482734


  27. Subramanian P, Locatelli-Hoops S, Kenealey J, DesJardin J, Notari L, Becerra SP. Pigment epithelium-derived factor (PEDF) prevents retinal cell death via PEDF Receptor (PEDF-R): identification of a functional ligand binding site. Volume 288 of Issue 33. The Journal of biological chemistry 2013. PMID: 23818523


  28. DesJardin JT, Holmes AL, Forcelli PA, Cole CE, Gale JT, Wellman LL, Gale K, Malkova L. Defense-like behaviors evoked by pharmacological disinhibition of the superior colliculus in the primate. Volume 33 of Issue 1. The Journal of neuroscience : the official journal of the Society for Neuroscience 2013. PMID: 23283329


  29. Holmes AL, Forcelli PA, DesJardin JT, Decker AL, Teferra M, West EA, Malkova L, Gale K. Superior colliculus mediates cervical dystonia evoked by inhibition of the substantia nigra pars reticulata. Volume 32 of Issue 38. The Journal of neuroscience : the official journal of the Society for Neuroscience 2012. PMID: 22993447


  30. West EA, DesJardin JT, Gale K, Malkova L. Transient inactivation of orbitofrontal cortex blocks reinforcer devaluation in macaques. Volume 31 of Issue 42. The Journal of neuroscience : the official journal of the Society for Neuroscience 2011. PMID: 22016546