Cynthia Delgado, MD

Associate Professor

VA Medicine Home, Nephrology

My emerging research program is at a crossroads of chronic kidney disease, quality of life and outcomes related research. CKD is a major public health issue and its prevalence is expected to grow at an alarming rate in the United States. Frailty has been shown to be more common among individuals with CKD than among those with normal kidney function. There are no current therapies that adequately address frailty in CKD, resulting in a major burden of morbidity, mortality and cost. I hope to create a body of work that will lay the foundation for addressing these major outcomes.

Education
Clinical Fellowship, - , University of California, San Francisco
Honors and Awards
  • Innovators Network Accelerator, Department of Veterans Affairs, 2016-2017
  • Career Development Award, Department of Veterans Affairs, 2012-2017
Publications
  1. Delgado C, Chiang JM, Kittiskulnam P, Sheshadri A, Grimes B, Segal M, Kaysen GA, Johansen KL. Longitudinal Assessment of Body Composition and Its Association With Survival Among Participants of the ACTIVE/ADIPOSE Study. 2021. PMID: 34930665


  2. Delgado C, Baweja M, Crews D, Eneanya N, Gadegbeku C, Inker L, Mendu M, Miller WG, Moxey-Mims M, Roberts G, St Peter W, Warfield C, Powe N. A Unifying Approach for GFR Estimation: Recommendations of the NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Disease. Journal of the American Society of Nephrology : JASN 2021. PMID: 34556489


  3. Delgado C, Baweja M, Crews DC, Eneanya ND, Gadegbeku CA, Inker LA, Mendu ML, Miller WG, Moxey-Mims MM, Roberts GV, St Peter WL, Warfield C, Powe NR. A Unifying Approach for GFR Estimation: Recommendations of the NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Disease. 2021. PMID: 34563581


  4. Sheshadri A, Kittiskulnam P, Delgado C, Sudore RL, Lai JC, Johansen KL. Association of Cognitive Function Screening Results with Adherence and Performance in a Pedometer-Based Intervention. American journal of nephrology 2021. PMID: 33979802


  5. Delgado C, Baweja M, Burrows NR, Crews DC, Eneanya ND, Gadegbeku CA, Inker LA, Mendu ML, Miller WG, Moxey-Mims MM, Roberts GV, St Peter WL, Warfield C, Powe NR. Reassessing the Inclusion of Race in Diagnosing Kidney Diseases: An Interim Report From the NKF-ASN Task Force. American journal of kidney diseases : the official journal of the National Kidney Foundation 2021. PMID: 33845065


  6. Delgado C, Baweja M, Burrows NR, Crews DC, Eneanya ND, Gadegbeku CA, Inker LA, Mendu ML, Miller WG, Moxey-Mims MM, Roberts GV, St Peter WL, Warfield C, Powe NR. Reassessing the Inclusion of Race in Diagnosing Kidney Diseases: An Interim Report from the NKF-ASN Task Force. Journal of the American Society of Nephrology : JASN 2021. PMID: 33837122


  7. Delgado C, Johansen KL. Revisiting serum creatinine as an indicator of muscle mass and a predictor of mortality among patients on hemodialysis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2020. PMID: 33275759


  8. Chiang JM, Delgado C, Kaysen GA, Segal MR, Chertow GM, Johansen KL. Correlates and Consequences of High Serum Irisin Concentration in Patients on Hemodialysis: A Longitudinal Analysis. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 2020. PMID: 33262071


  9. Matsuzawa R, Suzuki Y, Yamamoto S, Harada M, Watanabe T, Shimoda T, Yoshida A, Delgado C, Tamaki A, Matsunaga A, Roshanravan B. Determinants of Health-Related Quality of Life and Physical Performance-Based Components of Frailty in Patients Undergoing Hemodialysis. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 2020. PMID: 32981832


  10. Sheshadri A, Kittiskulnam P, Delgado C, Sudore R, Lai JC, Johansen KL. Association of motivations and barriers with participation and performance in a pedometer-based intervention. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2020. PMID: 32437568


  11. Delgado C. Frailty and CKD: Chicken or the Egg? Clinical journal of the American Society of Nephrology : CJASN 2019. PMID: 31628119


  12. Chiang JM, Kaysen GA, Segal M, Chertow GM, Delgado C, Johansen KL. Low testosterone is associated with frailty, muscle wasting and physical dysfunction among men receiving hemodialysis: a longitudinal analysis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2018. PMID: 30085235


  13. Johansen KL, Delgado C, Kaysen GA, Chertow GM, Chiang J, Dalrymple LS, Segal MR, Grimes BA. Frailty among patients receiving hemodialysis: evolution of components and associations with mortality. The journals of gerontology. Series A, Biological sciences and medical sciences 2018. PMID: 30192916


  14. Chiang JM, Kaysen GA, Schafer AL, Delgado C, Johansen KL. Fibroblast Growth Factor 23 is Associated With Adiposity in Patients Receiving Hemodialysis: Possible Cross Talk Between Bone and Adipose Tissue. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 2018. PMID: 29606304


  15. Kaysen GA, Grimes B, Dalrymple LS, Chertow GM, Ishida JH, Delgado C, Segal M, Chiang J, Dwyer T, Johansen KL. Associations of lipoproteins with cardiovascular and infection-related outcomes in patients receiving hemodialysis. Journal of clinical lipidology 2017. PMID: 29361496


  16. Delgado C, Chertow GM, Kaysen GA, Dalrymple LS, Kornak J, Grimes B, Johansen KL. Associations of Body Mass Index and Body Fat With Markers of Inflammation and Nutrition Among Patients Receiving Hemodialysis. American journal of kidney diseases : the official journal of the National Kidney Foundation 2017. PMID: 28870376


  17. Lee BJ, McCulloch CE, Grimes BA, Chandran S, Allen IE, Delgado C, Hsu CY. Refining the Policy for Timing of Kidney Transplant Waitlist Qualification. Transplantation direct 2017. PMID: 28795146


  18. Johansen KL, Dalrymple LS, Delgado C, Chertow GM, Segal MR, Chiang J, Grimes B, Kaysen GA. Factors Associated with Frailty and Its Trajectory among Patients on Hemodialysis. Volume 12 of Issue 7. Clinical journal of the American Society of Nephrology : CJASN 2017. PMID: 28576906


  19. Kittiskulnam P, Chertow GM, Carrero JJ, Delgado C, Kaysen GA, Johansen KL. Sarcopenia and its individual criteria are associated, in part, with mortality among patients on hemodialysis. Kidney international 2017. PMID: 28318630


  20. Kittiskulnam P, Carrero JJ, Chertow GM, Kaysen GA, Delgado C, Johansen KL. Sarcopenia among patients receiving hemodialysis: weighing the evidence. Journal of cachexia, sarcopenia and muscle 2016. PMID: 27897415


  21. Johansen KL, Dalrymple LS, Glidden D, Delgado C, Kaysen GA, Grimes B, Chertow GM. Association of Performance-Based and Self-Reported Function-Based Definitions of Frailty with Mortality among Patients Receiving Hemodialysis. Clinical journal of the American Society of Nephrology : CJASN 2016. PMID: 26792529


  22. Delgado C, Grimes BA, Glidden DV, Shlipak M, Sarnak MJ, Johansen KL. Association of Frailty based on self-reported physical function with directly measured kidney function and mortality. BMC nephrology 2015. PMID: 26645070


  23. Kittiskulnam P, Chertow GM, Kaysen GA, Delgado C, Dalrymple LS, Johansen KL. Misclassification of Obesity by Body Mass Index Among Patients Receiving Hemodialysis. American journal of kidney diseases : the official journal of the National Kidney Foundation 2015. PMID: 26612278


  24. Molfino A, Kaysen GA, Chertow GM, Doyle J, Delgado C, Dwyer T, Laviano A, Rossi Fanelli F, Johansen KL. Validating Appetite Assessment Tools Among Patients Receiving Hemodialysis. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 2015. PMID: 26522141


  25. Delgado C, Shieh S, Grimes B, Chertow GM, Dalrymple LS, Kaysen GA, Kornak J, Johansen KL. Association of Self-Reported Frailty with Falls and Fractures among Patients New to Dialysis. American journal of nephrology 2015. PMID: 26381744


  26. Wanga S, Ceron CS, Delgado C, Joshi SK, Spaulding K, Walker JP, Song S, Olson JL, Lovett DH. Two Distinct Isoforms of Matrix Metalloproteinase-2 Are Associated with Human Delayed Kidney Graft Function. Volume 10 of Issue 9. PloS one 2015. PMID: 26379248


  27. Joshi SK, Lee L, Lovett DH, Kang H, Kim HT, Delgado C, Liu X. Novel intracellular N-terminal truncated matrix metalloproteinase-2 isoform in skeletal muscle ischemia-reperfusion injury. Volume 34 of Issue 3. Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2015. PMID: 26213293


  28. Dalrymple LS, Mu Y, Romano PS, Nguyen DV, Chertow GM, Delgado C, Grimes B, Kaysen GA, Johansen KL. Outcomes of infection-related hospitalization in Medicare beneficiaries receiving in-center hemodialysis. American journal of kidney diseases : the official journal of the National Kidney Foundation 2015. PMID: 25641061


  29. Johansen KL, Painter P, Delgado C, Doyle J. Characterization of physical activity and sitting time among patients on hemodialysis using a new physical activity instrument. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 2014. PMID: 25213326


  30. Johansen KL, Dalrymple LS, Delgado C, Kaysen GA, Kornak J, Grimes B, Chertow GM. Comparison of self-report-based and physical performance-based frailty definitions among patients receiving maintenance hemodialysis. American journal of kidney diseases : the official journal of the National Kidney Foundation 2014. PMID: 24793033


  31. Delgado C, Ward P, Chertow GM, Storer L, Dalrymple L, Block T, Kaysen GA, Kornak J, Grimes B, Kutner NG, Johansen KL. Calibration of the brief food frequency questionnaire among patients on dialysis. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 2014. PMID: 24613023


  32. Johansen KL, Dalrymple LS, Delgado C, Kaysen GA, Kornak J, Grimes B, Chertow GM. Association between body composition and frailty among prevalent hemodialysis patients: a US Renal Data System special study. Journal of the American Society of Nephrology : JASN 2013. PMID: 24158987


  33. Delgado C, Frassetto L. Hip fractures in hemodialysis patients. American journal of kidney diseases : the official journal of the National Kidney Foundation 2013. PMID: 24054940


  34. Johansen KL, Delgado C, Bao Y, Kurella Tamura M. Frailty and dialysis initiation. Seminars in dialysis 2013. PMID: 24004376


  35. Delgado C, Doyle JW, Johansen KL. Association of frailty with body composition among patients on hemodialysis. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 2013. PMID: 23648049


  36. Delgado C, Johansen KL. Barriers to exercise participation among dialysis patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2011. PMID: 21795245


  37. Delgado C, Johansen KL. Deficient counseling on physical activity among nephrologists. Nephron. Clinical practice 2010. PMID: 20664289