The Journal of urology
Authors: Markland AD, Vaughan C, Huang AJ, Kim E, Bubes VY, Tangpricha V, Buring J, Lee IM, Cook N, Manson JE, Grodstein F
Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine
Authors: McKelvey MC, Bradbury I, McDowell C, Calfee CS, Weldon S, O'Kane CM, McAuley DF, Taggart CC
Volume 14 of Issue 17 | Cancers
Authors: Wagner MJ, Hennessy C, Beeghly A, French B, Shah DP, Croessmann S, Vilar-Compte D, Ruiz-Garcia E, Ingham M, Schwartz GK, Painter CA, Chugh R, Fecher L, Park C, Zamulko O, Trent JC, Subbiah V, Khaki AR, Tachiki L, Nakasone ES, Loggers ET, Labaki C, Saliby RM, McKay RR, Ajmera A, Griffiths EA, Puzanov I, Tap WD, Hwang C, Tejwani S, Jhawar SR, Hayes-Lattin B, Wulff-Burchfield E, Kasi A, Reuben DY, Nagaraj G, Joshi M, Polimera H, Kulkarni AA, Esfahani K, Kwon DH, Paoluzzi L, Bilen MA, Durbin EB, Grivas P, Warner JL, Davis EJ, COVID-19 and Cancer Consortium
BACKGROUND
Patients with sarcoma often require individualized treatment strategies and are likely to receive aggressive immunosuppressive therapies, which may place them at higher risk for severe COVID-19. We aimed to describe demographics, risk factors, and outcomes for patients with sarcoma and COVID-19.
METHODS
We performed a retrospective cohort study of patients with sarcoma and COVID-19 reported to the COVID-19 and Cancer Consortium (CCC19) registry (NCT04354701) from 17 March 2020 to 30 September 2021. Demographics, sarcoma histologic type, treatments, and COVID-19 outcomes were analyzed.
RESULTS
of 281 patients, 49% ( = 139) were hospitalized, 33% ( = 93) received supplemental oxygen, 11% ( = 31) were admitted to the ICU, and 6% ( = 16) received mechanical ventilation. A total of 23 (8%) died within 30 days of COVID-19 diagnosis and 44 (16%) died overall at the time of analysis. When evaluated by sarcoma subtype, patients with bone sarcoma and COVID-19 had a higher mortality rate than patients from a matched SEER cohort (13.5% vs 4.4%). Older age, poor performance status, recent systemic anti-cancer therapy, and lung metastases all contributed to higher COVID-19 severity.
CONCLUSIONS
Patients with sarcoma have high rates of severe COVID-19 and those with bone sarcoma may have the greatest risk of death.
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EClinicalMedicine
Authors: Fieldhouse JK, Randhawa N, Fair E, Bird B, Smith W, Mazet JAK
European heart journal. Digital health
Authors: Zheng C, Sun BC, Wu YL, Ferencik M, Lee MS, Redberg RF, Kawatkar AA, Musigdilok VV, Sharp AL
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
Authors: Anstey J, Jensen T, Lalani F, Conner SM
Frontiers in oncology
Authors: Galactionova K, Loibl S, Salari P, Marm? F, Martin M, Untch M, Bonnefoi HR, Kim SB, Bear HD, McCarthy N, Gelmon KA, Garc?a-S?enz JA, Kelly CM, Reimer T, Toi M, Rugo HS, Gnant M, Makris A, Burchardi N, Schwenkglenks M
The Lancet. Respiratory medicine
Authors: Conrad C, Looney MR
The Lancet. Respiratory medicine
Authors: Solomon JJ, Danoff SK, Woodhead FA, Hurwitz S, Maurer R, Glaspole I, Dellaripa PF, Gooptu B, Vassallo R, Cox PG, Flaherty KR, Adamali HI, Gibbons MA, Troy L, Forrest IA, Lasky JA, Spencer LG, Golden J, Scholand MB, Chaudhuri N, Perrella MA, Lynch DA, Chambers DC, Kolb M, Spino C, Raghu G, Goldberg HJ, Rosas IO, TRAIL1 Network Investigators
The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception
Authors: Krans EE, Chen BA, Rothenberger SD, Bogen DL, Jones K, Turocy MJ, Klocke LC, Schwarz EB
