AIDS and behavior
Authors: Neduzhko O, Postnov O, Sereda Y, Kulchynska R, Bingham T, Myers JJ, Flanigan T, Kiriazova T
The New England journal of medicine
Authors: Gandhi M, Yokoe DS, Havlir DV
Journal of medical Internet research
Authors: Elnaggar A, Ta Park V, Lee SJ, Bender M, Siegmund LA, Park LG
Genetics in medicine : official journal of the American College of Medical Genetics
Authors: Li MM, Chao E, Esplin ED, Miller DT, Nathanson KL, Plon SE, Scheuner MT, Stewart DR, ACMG Professional Practice and Guidelines Committee
Authors: Onopiuk M, Eby B, Nesin V, Ngo P, Lerner M, Gorvin CM, Stokes VJ, Thakker RV, Brandi ML, Chang W, Humphrey MB, Tsiokas L, Lau K
Medical Science Educator
Authors: Altneu E, Grieco CA, Verbeck N, Davis JA, Clinchot DM
Genetics
Authors: Mak ACY, Sajuthi S, Joo J, Xiao S, Sleiman PM, White MJ, Lee EY, Saef B, Hu D, Gui H, Keys KL, Lurmann F, Jain D, Abecasis G, Kang HM, Nickerson DA, Germer S, Zody MC, Winterkorn L, Reeves C, Huntsman S, Eng C, Salazar S, Oh SS, Gilliland FD, Chen Z, Kumar R, Martínez FD, Wu AC, Ziv E, Hakonarson H, Himes BE, Williams LK, Seibold MA, Burchard EG
Kardiologia polska
Authors: Lee CW, Sung SH, Huang WM, Tsai YL, Hsu CP, Yu WC
Volume 84 of Issue 6 | Circulation journal : official journal of the Japanese Circulation Society
Authors: Warisawa T, Cook CM, Seligman H, Howard JP, Ahmad Y, Rajkumar C, Doi S, Nakayama M, Tanigaki T, Omori H, Nakajima A, Yamanaka F, Goto S, Yakuta Y, Karube K, Uetani T, Kikuta Y, Shiono Y, Kawase Y, Nishina H, Nakamura S, Escaned J, Akashi YJ, Matsuo H, Davies JE
BACKGROUND
The per-vessel level impact of physiological pattern of disease on the discordance between fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) has not been clarified.Methods and Results:Using the AJIP registry, vessels with FFR/iFR discordance (133/671 [19.8%]) were analyzed. In the left anterior descending artery (LAD), physiologically diffuse disease, as assessed by pressure-wire pullback, was associated with FFR-/iFR+ (83.3% [40/48]), while physiologically focal disease was associated with FFR+/iFR- (57.4% [31/54]), significantly (P<0.0001). These differences were not significant in non-LAD (P=0.17).
CONCLUSIONS
The impact of physiological pattern of disease on FFR/iFR discordance is more pronounced in the LAD.
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