Hypotheses about sub-optimal hydration in the weeks before coronavirus disease (COVID-19) as a risk factor for dying from COVID-19.

ALK Testing Trends and Patterns Among Community Practices in the United States.

Viral latency in HIV disease.

Emerging Precision Medicine Approaches for Lung Neuroendocrine Tumors.

Mark Anderson, MD, PhD

Vancomycin for Staphylococcus aureus endocarditis in intravenous drug users.

Long-term outcomes of patients with chronic kidney disease.

Sphingosine kinase activation mediates ischemic preconditioning in murine heart.

Isolation of subpopulations of high density lipoproteins: three particle species containing apoE and two species devoid of apoE that have affinity for heparin.

At what flow rate does the aortic valve gradient become severely elevated? Implications for guideline recommendations on aortic valve area cutoffs

Carboplatin in BRCA1/2-mutated and triple-negative breast cancer BRCAness subgroups: the TNT Trial.

Ashwin Kotwal and research team published article in JAGS

Ashwin A. Kotwal MD, MS, Irena Cenzer PhD, Lauren J. Hunt RN, PhD, FNP-BC, Claire Ankuda MD, MPH, MSc, Jacqueline M. Torres PhD, Alexander K. Smith MD, MS, MPH, Melissa Aldridge PhD, MBA, and Krista L. Harrison PhD published "Psychosocial distress among spouses of persons with dementia before and after their partner's death" in JAGS.

Key Points:

• This study compares the psychosocial needs of spouses of persons living with dementia with spouses of persons with no cognitive impairment 2 years before and after their partner's death using a nationally representative survey.
• Before their partner's death, spouses of persons living with dementia had increased loneliness and depressive symptoms and lower life satisfaction compared with spouses of persons with no cognitive impairment.
• After their partner's death, spouses had strikingly high levels of loneliness and depression persisting for 2 years that were similar across their partner's cognitive status.

Reflecting on these findings, the editor notes: "As clinicians, we should be mindful that serious illness in a spouse is itself a cause of suffering that begins in the period before death and can be greatly magnified in its aftermath. We need better ways to support all spouses as they move through their loved ones' final illness and death, especially those who may be most vulnerable to sustained distress and prolonged grief." -Soo Borson, MD

Public health and international drug policy.

Estimated GFR and Subsequent Higher Left Ventricular Mass in Young and Middle-Aged Adults With Normal Kidney Function: The Coronary Artery Risk Development in Young Adults (CARDIA) Study.

Association of markers of hemostasis with death in HIV-infected women.