Publications

Department of Medicine faculty members published more than 3,600 peer-reviewed articles in 2024.

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The New England journal of medicine

New insights into the dementia epidemic.

2013

Authors: Larson EB, Yaffe K, Langa KM

Volume 1841 of Issue 3 | Biochimica et biophysica acta

Role of cholesterol sulfate in epidermal structure and function: lessons from X-linked ichthyosis.

2013

Authors: Elias PM, Williams ML, Choi EH, Feingold KR

View Abstract

X-linked ichthyosis is a relatively common syndromic form of ichthyosis most often due to deletions in the gene encoding the microsomal enzyme, steroid sulfatase, located on the short area of the X chromosome. Syndromic features are mild or unapparent unless contiguous genes are affected. In normal epidermis, cholesterol sulfate is generated by cholesterol sulfotransferase (SULT2B1b), but desulfated in the outer epidermis, together forming a 'cholesterol sulfate cycle' that potently regulates epidermal differentiation, barrier function and desquamation. In XLI, cholesterol sulfate levels my exceed 10% of total lipid mass (≈1% of total weight). Multiple cellular and biochemical processes contribute to the pathogenesis of the barrier abnormality and scaling phenotype in XLI. This article is part of a Special Issue entitled The Important Role of Lipids in the Epidermis and their Role in the Formation and Maintenance of the Cutaneous Barrier. Guest Editors: Kenneth R. Feingold and Peter Elias.

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Circulation

Abstract 19014: Significant Major Complication Occurrence in Extracting Riata Compared to Sprint Fidelis Leads.

2013

Authors: Harshal Sheth, Michael Broman, Amit Mehrotra, Dina Sparano, John Shin, Joshua Moss, Hemal Nayak, Martin Burke

Circulation

Abstract 18926: Pre-Implant Surface EKG Screening Predicts the Arrhythmia Detection Vector Utilized by an Entirely Subcutaneous Implantable Defibrillator System.

2013

Authors: Joshua D Moss, Lizbeth Mino, Bradley Knight, John F Beshai, Hemal M Nayak, Martin C Burke

Circulation

Abstract 18511: Early Re-Implantation After Infected Device Extraction is Safe, Reduces Length of Stay and is Not Associated With a Higher Rate of Reinfection.

2013

Authors: Dina M Sparano, Kyle J Ericson, Michael T Broman, Amit K Mehrotra, Harshal Sheth, John H Shin, Martin C Burke, Joshua D Moss, Hemal M Nayak

Circulation

Abstract 18575: Quantitative Assessment of Aortic Valve Calcification by Cardiac CT in the Penn Diabetes Heart Study: Association With Cardiovascular Risk Factors and Coronary Artery Calcium.

2013

Authors: Hashmi Rafeek, Tim Churchill, Suraj Rasania, Karen Terembula, Victor Ferrari, Claire Mulvey, Atif Qasim, Muredach Reilly

Circulation

The echo score revisited: Impact of incorporating commissural morphology and leaflet displacement to the prediction of outcome for patients undergoing percutaneous mitral valvuloplasty.

2013

Authors: Nunes MC, Tan TC, Elmariah S, do Lago R, Margey R, Cruz-Gonzalez I, Zheng H, Handschumacher MD, Inglessis I, Palacios IF, Weyman AE, Hung J

PLoS medicine

Interactions between non-physician clinicians and industry: a systematic review.

2013

Authors: Grundy Q, Bero L, Malone R

Circulation. Heart failure

Renal function trajectories and clinical outcomes in acute heart failure.

2013

Authors: Givertz MM, Postmus D, Hillege HL, Mansoor GA, Massie BM, Davison BA, Ponikowski P, Metra M, Teerlink JR, Cleland JG, Dittrich HC, O'Connor CM, Cotter G, Voors AA

Circulation. Heart failure

Predictors of postdischarge outcomes from information acquired shortly after admission for acute heart failure: a report from the Placebo-Controlled Randomized Study of the Selective A1 Adenosine Receptor Antagonist Rolofylline for Patients Hospitalized W

2013

Authors: Cleland JG, Chiswell K, Teerlink JR, Stevens S, Fiuzat M, Givertz MM, Davison BA, Mansoor GA, Ponikowski P, Voors AA, Cotter G, Metra M, Massie BM, O'Connor CM