Clinical cancer research : an official journal of the American Association for Cancer Research
Authors: Kelley RK, Meyer T, Rimassa L, Merle P, Park JW, Yau T, Chan SL, Blanc JF, Tam VC, Tran A, Dadduzio V, Markby DW, Kaldate R, Cheng AL, El-Khoueiry AB, Abou-Alfa GK
PloS one
Authors: Bahrainwala L, Knoblauch AM, Andriamiadanarivo A, Diab MM, McKinney J, Small PM, Kahn JG, Fair E, Rakotosamimanana N, Grandjean Lapierre S
International journal of environmental research and public health
Authors: Almoznino G, Abramovitz I, Kessler Baruch O, Kedem R, Protter NE, Levine J, Bader T, Yavnai N, Zur D, Mijiritsky E, Shay B
Volume 117 of Issue 29 | Proceedings of the National Academy of Sciences of the United States of America
Authors: Müller NF, Stolz U, Dudas G, Stadler T, Vaughan TG
Reassortment is an important source of genetic diversity in segmented viruses and is the main source of novel pathogenic influenza viruses. Despite this, studying the reassortment process has been constrained by the lack of a coherent, model-based inference framework. Here, we introduce a coalescent-based model that allows us to explicitly model the joint coalescent and reassortment process. In order to perform inference under this model, we present an efficient Markov chain Monte Carlo algorithm to sample rooted networks and the embedding of phylogenetic trees within networks. This algorithm provides the means to jointly infer coalescent and reassortment rates with the reassortment network and the embedding of segments in that network from full-genome sequence data. Studying reassortment patterns of different human influenza datasets, we find large differences in reassortment rates across different human influenza viruses. Additionally, we find that reassortment events predominantly occur on selectively fitter parts of reassortment networks showing that on a population level, reassortment positively contributes to the fitness of human influenza viruses.
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Journal of Clinical and Translational Science
Authors: Towfighi A, Orechwa AZ, Aragón TJ, Atkins M, Brown AF, Brown J, Carrasquillo O, Carson S, Fleisher P, Gustafson E, Herman DK, Inkelas M, Liu W, Meeker D, Mehta T, Miller DC, Paul-Brutus R, Potter MB, Rittner SS, Rodriguez B, Rusch D, Skinner A, Yee HF
JAMA neurology
Authors: Leary EB, Watson KT, Ancoli-Israel S, Redline S, Yaffe K, Ravelo LA, Peppard PE, Zou J, Goodman SN, Mignot E, Stone KL
Cancer
Authors: Borno HT, Lin TK, Batniji RS
International journal for equity in health
Authors: Rice WS, Fletcher FE, Akingbade B, Kan M, Whitfield S, Ross S, Gakumo CA, Ofotokun I, Konkle-Parker DJ, Cohen MH, Wingood GM, Pence BW, Adimora AA, Taylor TN, Wilson TE, Weiser SD, Kempf MC, Turan B, Turan JM
Current HIV/AIDS reports
Authors: Drain PK, Bardon AR, Simoni JM, Cressey TR, Anderson P, Sevenler D, Olanrewaju AO, Gandhi M, Celum C
