Warren Gold, MD

Professor Emeritus

Dr. Gold received is M.D. degree from Harvard Medical School in 1959. After internal medicine and chief medical residency at the Beth Israel Hospital in Boston (1959-62), he received his research training at the Cardiovascular Research Institute, UCSF with Jay A. Nadel and Julius H. Comroe, Jr., (1962-65) and then joined the faculty of Harvard Medical School at Children’s Hospital in 1965 where he set up a new pulmonary laboratory for Dr. Alexander Nadas to study the pulmonary problems of children with congenital heart disease. He joined the faculty in the Pulmonary Division at UCSF in 1969 and became the Director of the Adult Pulmonary Laboratories, CVRI, UCSF in 1980. His major academic activities include clinical research programs, training pre and post-doctoral fellows in all four schools in systems physiology, supervision of the Adult Pulmonary Laboratories, and consulting with industry on systems physiology.

Research Interests

Study of the function of the respiratory system under resting conditions may provide first clues about the presence of significant respiratory disease. Study of the respiratory system during the stress of exercise, may under cover evidence of such diseases at a much earlier stage. Repeated studies can define the natural history of those diseases and the effects of therapeutic interventions. Current research, as a member of the FAMRI (Flight Attendants Medical Research Institute) Center of Excellence, PI Neal Benowitz) is designed to examine the long-term effects of second hand cigarette smoke on flight attendants. Pilot studies have demonstrated that 40% of nonsmoking flight attendants who worked on commercial airlines prior to the ban on cigarette smoking developed diffusion defects associated with airway obstruction and air trapping. During exercise, all pre-ban flight attendants show an abnormally limited increase in diffusing capacity with increased pulmonary blood flow. Current studies are designed to compare lung function at rest and during exercise in pre-ban fight attendants with post-ban flight attendants, and nonsmokers who live and work at sea level stratified by second-hand smoke exposure.

Publications
  1. Chen J, Weldemichael L, Zeng S, Giang B, Geerts J, Ching WC, Nishihama M, Gold WM, Arjomandi M. Actigraphy informs distinct patient-centered outcomes in Pre-COPD. Respiratory medicine 2021. PMID: 34496341


  2. Arjomandi M, Zeng S, Geerts J, Stiner RK, Bos B, van Koeverden I, Keene J, Elicker B, Blanc PD, Gold WM. Lung volumes identify an at-risk group in persons with prolonged secondhand tobacco smoke exposure but without overt airflow obstruction. Volume 5 of Issue 1. BMJ open respiratory research 2018. PMID: 29755755


  3. Arjomandi M, Haight T, Sadeghi N, Redberg R, Gold WM. Reduced exercise tolerance and pulmonary capillary recruitment with remote secondhand smoke exposure. Volume 7 of Issue 4. PloS one 2012. PMID: 22493689


  4. Hardie GE, Brown JK, Gold WM. Bronchial hyperresponsiveness, word descriptors, and ethnicity: women with mild asthma. The Journal of asthma : official journal of the Association for the Care of Asthma 2011. PMID: 22176690


  5. Hardie GE, Liu R, Darden J, Gold WM. Recruitment of asthmatic ethnic minorities into a methacholine research study: factors influencing participation. Journal of the National Medical Association 2011. PMID: 21443066


  6. Hardie G, Liu R, Darden J, Gold WM. Ethnic differences in methacholine responsiveness and word descriptors in African Americans, Hispanic-Mexican Americans, Asian-Pacific Islanders, and Whites with mild asthma. The Journal of asthma : official journal of the Association for the Care of Asthma 2010. PMID: 20528591


  7. Arjomandi M, Haight T, Redberg R, Gold WM. Pulmonary function abnormalities in never-smoking flight attendants exposed to secondhand tobacco smoke in the aircraft cabin. Volume 51 of Issue 6. Journal of occupational and environmental medicine 2009. PMID: 19448573


  8. Ren X, Hsu PY, Dulbecco FL, Fleischmann KE, Gold WM, Redberg RF, Schiller NB. Remote second-hand tobacco exposure in flight attendants is associated with systemic but not pulmonary hypertension. Volume 15 of Issue 4. Cardiology journal 2008. PMID: 18698542


  9. Hardie GE, Brown JK, Gold WM. Adrenergic responsiveness: FEV1 and symptom differences in Whites and African Americans with mild asthma. The Journal of asthma : official journal of the Association for the Care of Asthma 2007. PMID: 17943572


  10. Davis AH, Carrieri-Kohlman V, Janson SL, Gold WM, Stulbarg MS. Effects of treatment on two types of self-efficacy in people with chronic obstructive pulmonary disease. Journal of pain and symptom management 2006. PMID: 16824986


  11. Janson SL, Fahy JV, Covington JK, Paul SM, Gold WM, Boushey HA. Effects of individual self-management education on clinical, biological, and adherence outcomes in asthma. Volume 115 of Issue 8. The American journal of medicine 2003. PMID: 14656614


  12. Hardie GE, Gold WM, Janson S, Carrieri-Kohlman V, Boushey HA. Understanding how asthmatics perceive symptom distress during a methacholine challenge. The Journal of asthma : official journal of the Association for the Care of Asthma 2002. PMID: 12442950


  13. Stulbarg MS, Carrieri-Kohlman V, Demir-Deviren S, Nguyen HQ, Adams L, Tsang AH, Duda J, Gold WM, Paul S. Exercise training improves outcomes of a dyspnea self-management program. Journal of cardiopulmonary rehabilitation 2002. PMID: 11984209