Vasanth Vedantham, MD, PhD

Professor In Residence

CLINICAL INTERESTS: Dr. Vedantham is cardiologist and clinical cardiac electrophysiologist, specializing in treatment of heart rhythm disorders using catheter ablation, pacemaker and defibrillator implantation, and antiarrhythmic medications. In addition to treating patients with supraventricular tachycardia, ventricular tachycardia, atrial fibrillation, conduction system disease, cardiac arrest, and syncope, he is particularly interested in inherited arrhythmia syndromes (including long QT syndrome, Brugada syndrome, CPVT, and others) as well as inherited and acquired arrhythmogenic cardiomyopathies, especially cardiac sarcoidosis.

RESEARCH INTERESTS: Dr. Vedantham's research explores the biogenesis of heart rhythm in normal and diseased hearts, with particular interests in sinus node dysfunction, cardiac conduction system disease, and atrial fibrillation. His current focus is on the development and function of pacemaker cells in the sinoatrial node. He has characterized the transcriptome of this rare but critical cell type and identified specific gene regulatory networks active in these cells. His lab is currently focused on building a comprehensive model for development, normal and diseased physiology, and regenerative potential of specialized cells responsible for heart rhythm.

Education
Fellowship, 2010 - Cardiac Electrophysiology, University of California, San Francisco
Fellowship, 2008 - Cardiology, University of California, San Francisco
Residency, 2004 - Internal Medicine, Brigham and Women's Hospital
M.D., 2002 - School of Medicine, Harvard Medical School/M.I.T.
PhD, 2002 - Neuroscience, Harvard University
BS/MS, 1993 - Physics and Biochemistry, Yale University
Websites
Publications

  1. Satoshi Higuchi, Edward P. Gerstenfeld, Adam C. Lee, Byron Lee, Gregory M. Marcus, Henry H. Hsia, Joshua D. Moss, Randall J. Lee, Thomas A. Dewland, Vasanth Vedantham, Zian H. Tseng, Melvin M. Scheinman. MP-470554-001 THE VALUE OF FUNCTIONAL FACSICULAR BLOCK IN PATIENTS WITH ATRIOVENTRICULAR REENTRANT TACHYCARDIA. Heart rhythm 2024. PMID:


  2. Dhuha Manhil, Thomas C. Crawford, Frank M. Bogun, Xiaokui Gu, Alexandru B. Chicos, Henri Roukoz, Peter J. Zimetbaum, Francis D. Murgatroyd, Lynda E. Rosenfeld, Kyoko Soejima, Adarsh K. Bhan, Vasanth Vedantham, Timm-Michael L. Dickfeld, David B. De Lurgio, Pyotr G. Platonov, Calambur Narasimhan, Kristen K. Patton, David Rosenthal, SIDDHARTH S. MUKERJI, Christopher Madias, Steven Jack Kalbfl eisch, Mikhail Torosoff, Kenneth A. Ellenbogen, Jordana Kron. SEX DIFFERENCES IN CARDIAC SARCOIDOSIS TREATMENT AND OUTCOMES: FINDINGS FROM THE CARDIAC SARCOIDOSIS CONSORTIUM. Journal of the American College of Cardiology 2024. PMID:


  3. Garbutt TA, Wang Z, Wang H, Ma H, Ruan H, Dong Y, Xie Y, Tan L, Phookan R, Stouffer J, Vedantham V, Yang Y, Qian L, Liu J. Epigenetic Regulation of Cardiomyocyte Maturation by Arginine Methyltransferase CARM1. Circulation 2024. PMID: 38223978


  4. Ciuffo L, Tung M, Dukes JW, Vittinghoff E, Moss JD, Lee RJ, Lee BK, Tseng ZH, Vedantham V, Olgin JE, Scheinman MM, Hsia H, Ramchandani VA, Gerstenfeld EP, Marcus GM. Acute alcohol exposure and electrocardiographic changes: Finding from the HOLIDAY trial. Journal of electrocardiology 2024. PMID: 38295539


  5. Ruan H, Mandla R, Ravi N, Galang G, Soe AW, Olgin JE, Lang D, Vedantham V. Cholecystokinin-A signaling regulates automaticity of pacemaker cardiomyocytes. Frontiers in physiology 2023. PMID: 38179138


  6. Myadam R, Crawford TC, Bogun FM, Gu X, Ellenbogen KA, Jasti S, Chicos AB, Roukoz H, Zimetbaum PJ, Kalbfleisch SJ, Murgatroyd FD, Steckman DA, Rosenfeld LE, Garlitski AC, Soejima K, Bhan AK, Vedantham V, Dickfeld TL, De Lurgio DB, Platonov PG, Zipse MM, Nishiuchi S, Ortman ML, Narasimhan C, Patton KK, Rosenthal DG, Mukerji SS, Hoogendoorn JC, Zeppenfeld K, Sauer WH, Kron J, Cardiac Sarcoidosis Consortium. Reply: Association of Adverse Events With the Different Diagnostic Schemes of Cardiac Sarcoidosis. JACC. Clinical electrophysiology 2023. PMID: 38151306


  7. Engel JL, Zhang X, Lu DR, Vila OF, Arias V, Lee J, Hale C, Hsu YH, Li CM, Vedantham V, Ang YS. Single Cell Multi-Omics of an iPSC Model of Human Sinoatrial Node Development Reveals Genetic Determinants of Heart Rate and Arrhythmia Susceptibility. bioRxiv : the preprint server for biology 2023. PMID: 37425707


  8. Ruan H, Mandla R, Ravi N, Galang G, Soe AW, Olgin JE, Lang D, Vedantham V. Cholecystokinin-A Signaling Regulates Automaticity of Pacemaker Cardiomyocytes and Shortens Sinus Node Recovery Time. bioRxiv : the preprint server for biology 2023. PMID: 36747643


  9. Kheiri B, Vedantham V, Scheinman M. A very wide complex tachycardia. Heart rhythm 2023. PMID: 37245898


  10. Myadam R, Crawford TC, Bogun FM, Gu X, Ellenbogen KA, Jasti S, Chicos AB, Roukoz H, Zimetbaum PJ, Kalbfleisch SJ, Murgatroyd FD, Steckman DA, Rosenfeld LE, Garlitski AC, Soejima K, Bhan AK, Vedantham V, Dickfeld TL, De Lurgio DB, Platonov PG, Zipse MM, Nishiuchi S, Ortman ML, Narasimhan C, Patton KK, Rosenthal DG, Mukerji SS, Hoogendoorn JC, Zeppenfeld K, Sauer WH, Kron J, Cardiac Sarcoidosis Consortium. Risk of Adverse Outcomes Associated With Cardiac Sarcoidosis Diagnostic Schemes. JACC. Clinical electrophysiology 2023. PMID: 37227359


  11. Luisa Ciuffo, Monica Tung, Jonathan W. Dukes, Eric Vittinghoff, Joshua D. Moss, Randall J. Lee, Byron K. Lee, Zian H. Tseng, Vasanth Vedantham, Jeffrey E. Olgin, Melvin M. Scheinman, Henry H. Hsia, Edward P. Gerstenfeld, Gregory M. Marcus. ACUTE ALCOHOL EXPOSURE AND ELECTROCARDIOGRAPHIC CHANGES: FINDING FROM THE HOLIDAY (HOW ALCOHOL INDUCES ATRIAL TACHYARRHYTHMIAS) TRIAL. Journal of the American College of Cardiology 2023. PMID:


  12. Lee AC, Voskoboinik A, Cheung CC, Yogi S, Tseng ZH, Moss JD, Dewland TA, Lee BK, Lee RJ, Hsia HH, Marcus GM, Vedantham V, Chieng D, Kistler PM, Dillon W, Vittinghoff E, Gerstenfeld EP. A Randomized Trial of High vs Standard Power Radiofrequency Ablation for Pulmonary Vein Isolation: SHORT-AF. JACC. Clinical electrophysiology 2023. PMID: 37495318


  13. Howell SJ, Dukes JW, Vittinghoff E, Tang J, Moss JD, Lee RJ, Lee BK, Tseng ZH, Vedantham V, Olgin JE, Scheinman MM, Hsia H, Gerstenfeld EP, Marcus GM. Premature Atrial Contraction Location and Atrial Fibrillation Inducibility. Circulation. Arrhythmia and electrophysiology 2023. PMID: 36688298


  14. Dewland TA, Gerstenfeld EP, Moss JD, Lee AC, Vedantham V, Lee RJ, Tseng ZH, Hsia HH, Lee BK, Wall GC, Chang KR, Yang MH, Marcus GM. Randomized Comparison of a�Radiofrequency Wire Versus a�Radiofrequency Needle System for�Transseptal Puncture. JACC. Clinical electrophysiology 2022. PMID: 36752451


  15. Thomas A Dewland, Edward GERSTENFELD, Joshua Moss, Adam C Lee, Vasanth Vedantham, Randall J Lee, Zian Tseng, Henry H Hsia, byron K lee, Grace Wall, Kathleen Chang, Michelle Yang, Gregory M Marcus. Abstract 9803: Randomized Comparison of a Radiofrequency Wire versus a Radiofrequency Needle System for Transseptal Puncture. Circulation 2022. PMID:


  16. Higuchi S, Ito H, Gerstenfeld EP, Lee AC, Lee BK, Marcus GM, Hsia HH, Moss JD, Lee RJ, Dewland TA, Vedantham V, Tseng ZH, Patel AR, Tanel RE, Badhwar N, Pellegrini CN, Kawamura M, Shoda M, Hwang C, Refaat MM, Scheinman MM. The Value of Programmed Ventricular Extrastimuli From the Right Ventricular�Basal Septum During Supraventricular Tachycardia. JACC. Clinical electrophysiology 2022. PMID: 36858688


  17. Zhu L, Choudhary K, Gonzalez-Teran B, Ang YS, Thomas R, Stone NR, Liu L, Zhou P, Zhu C, Ruan H, Huang Y, Jin S, Pelonero A, Koback F, Padmanabhan A, Sadagopan N, Hsu A, Costa MW, Gifford CA, van Bemmel JG, Hüttenhain R, Vedantham V, Conklin BR, Black BL, Bruneau BG, Steinmetz L, Krogan NJ, Pollard KS, Srivastava D. Transcription Factor GATA4 Regulates Cell Type-Specific Splicing Through Direct Interaction With RNA in Human Induced Pluripotent Stem Cell-Derived Cardiac Progenitors. Circulation 2022. PMID: 35938400


  18. Bressi E, Crawford TC, Bogun FM, Gu X, Ellenbogen KA, Chicos AB, Roukoz H, Zimetbaum PJ, Kalbfleisch SJ, Murgatroyd FD, Steckman DA, Rosenfeld LE, Garlitski AC, Soejima K, Bhan AK, Vedantham V, Dickfeld TM, De Lurgio DB, Platonov PG, Zipse MM, Nishiuchi S, Ortman ML, Narasimhan C, Patton KK, Rosenthal DG, Mukerji SS, Hoogendoorn JC, Zeppenfeld K, Sauer WH, Kron J, Cardiac Sarcoidosis Consortium *. Arrhythmia Monitoring and Outcomes in Patients With Cardiac Sarcoidosis: Insights From the Cardiac Sarcoidosis Consortium. Journal of the American Heart Association 2022. PMID: 35730638


  19. Thomas C. Crawford, Jordana Kron, Xiaokui Gu, M. Rizwan Afzal, Alexandru B. Chicos, Henri Roukoz, Peter J. Zimetbaum, Francis D. Murgatroyd, Kathryn Martin, Mikhail Torosoff, David A. Steckman, Pyotr G. Platonov, Adarsh K. Bhan, Lynda E. Rosenfeld, David B. De Lurgio, Ann C. Garlitski, Vasanth Vedantham, Kyoko Soejima, Jason Appelbaum, Timm-Michael Dickfeld, Matthew L. Ortman, Kazuaki Kaitani, Suguru Nishiuchi, Calambur Narasimhan, Kristen K. Patton, David Rosenthal, Khaled Nour, Siddharth S. Mukerji, Katja Zeppenfeld, Matthew M. Zipse, Marc Judson, Marc Judson, William H. Sauer, Kenneth A. Ellenbogen, James Froehlich, Kim A. Eagle, Frank M. Bogun. CE-522-04 MORTALITY AND MORBIDITY OF CARDIAC SARCOIDOSIS: AN INTERNATIONAL REGISTRY. Heart rhythm 2022. PMID:


  20. Satoshi Higuchi, Hiroyuki Ito, Edward P. Gerstenfeld, Adam C. Lee, Byron K. Lee, Gregory M. Marcus, Henry H. Hsia, Joshua D. Moss, Randall J. Lee, Thomas A. Dewland, Vasanth Vedantham, Zian H. Tseng, Akash R. Patel, Ronn E. Tanel, Nitish Badhwar, Cara N. Pellegrini, Mitsuharu Kawamura, Morio Shoda, Chun Hwang, Marwan M. Refaat, Melvin M. Scheinman. EN-571-01 THE VALUE OF PROGRAMMED VENTRICULAR EXTRASTIMULI FROM THE RIGHT VENTRICULAR BASAL SEPTUM DURING SUPRAVENTRICULAR TACHYCARDIA. Heart rhythm 2022. PMID:


  21. Stacey Howell, Jonathan Walter Dukes, Eric Vittinghoff, Janet Tang, Joshua D. Moss, Randall J. Lee, Byron Lee, Zian H. Tseng, Vasanth Vedantham, Jeffrey E. Olgin, Melvin M. Scheinman, Henry H. Hsia, Edward P. Gerstenfeld, Gregory M. Marcus. PO-683-03 PREMATURE ATRIAL CONTRACTION LOCATION AND ATRIAL FIBRILLATION INDUCIBILITY. Heart rhythm 2022. PMID:


  22. Shilpa Jasti, Muhammad Afzal, Steven Jack Kalbfleisch, Kenneth A. Ellenbogen, Frank M. Bogun, Alexandru B. Chicos, Henri Roukoz, Peter J. Zimetbaum, Francis Murgatroyd, Mikhail Torosoff, Marc Judson, Pyotr G. Platonov, Adarsh K. Bhan, Lynda E. Rosenfeld, David B. De Lurgio, Ann C. Garlitski, Melody H. Hermel, Vasanth Vedantham, Kyoko Soejima, Timm-Michael L. Dickfeld, Xiaokui Gu, Eric Puroll, Thomas C. Crawford, Jordana Kron. CARDIAC SARCOIDOSIS PATIENTS WHO MEET THE 1993 AND 2006 JAPANESE DIAGNOSTIC CRITERIA ARE MORE LIKELY TO HAVE ADVERSE OUTCOMES. Journal of the American College of Cardiology 2022. PMID:


  23. Shilpa Jasti, Muhammad Afzal, Steven Jack Kalbfleisch, Kenneth A. Ellenbogen, Frank M. Bogun, Alexandru B. Chicos, Henri Roukoz, Peter J. Zimetbaum, Francis Murgatroyd, Mikhail Torosoff, Marc Judson, Pyotr G. Platonov, Adarsh K. Bhan, Lynda E. Rosenfeld, David B. De Lurgio, Ann C. Garlitski, Melody H. Hermel, Vasanth Vedantham, Kyoko Soejima, Timm-Michael L. Dickfeld, Xiaokui Gu, Eric Puroll, Thomas C. Crawford, Jordana Kron. TRADITIONAL RISK FACTORS INCREASE THE RISK OF POOR OUTCOMES IN PATIENTS WITH CARDIAC SARCOIDOSIS. Journal of the American College of Cardiology 2022. PMID:


  24. Siontis KC, Santangeli P, Muser D, Marchlinski FE, Zeppenfeld K, Hoogendoorn JC, Narasimhan C, Sauer WH, Zipse MM, Kapa S, Vedantham V, Rosenthal DG, Robinson MR, Patton KK, Murgatroyd F, Chicos AB, Soejima K, Roukoz H, Sacher F, Bhan A, Appelbaum J, Dickfeld T, Mankad P, Ellenbogen KA, Kron J, Kim HM, Froehlich J, Eagle KA, Bogun FM, Crawford TC. Outcomes Associated With Catheter Ablation of Ventricular Tachycardia in Patients With Cardiac Sarcoidosis. 2021. PMID: 34787643


  25. Marcus GM, Vittinghoff E, Whitman IR, Joyce S, Yang V, Nah G, Gerstenfeld EP, Moss JD, Lee RJ, Lee BK, Tseng ZH, Vedantham V, Olgin JE, Scheinman MM, Hsia H, Gladstone R, Fan S, Lee E, Fang C, Ogomori K, Fatch R, Hahn JA. Acute Consumption of Alcohol and Discrete Atrial Fibrillation Events. Annals of internal medicine 2021. PMID: 34461028


  26. Monica Tung, Eric Vittinghoff, Gregory Nah, David G. Rosenthal, Nitish Badhwar, Jonathan W. Dukes, Joshua D. Moss, Randall J. Lee, Byron Lee, Zian H. Tseng, Tomos E. Walters, Vasanth Vedantham, Rachel A. Gladstone, Shannon Mei-ling Fan, Christina D. Fang, Kelsey Ogomori, Emily Lee, Trisha F. Hue, Jeffrey E. Olgin, Melvin M. Scheinman, Vijay Ramchandani, Henry H. Hsia, Edward P. Gerstenfeld, Gregory M. Marcus. B-PO02-152 ELECTROCARDIOGRAPHIC CHANGES IN A DOUBLE-BLIND, PLACEBO-CONTROLLED RANDOMIZED TRIAL OF ETHANOL VERSUS PLACEBO. Heart rhythm 2021. PMID:


  27. Satoshi Higuchi, Jose M. Sanchez, Tomos E. Walters, Vasanth Vedantham, Henry H. Hsia, Edward P. Gerstenfeld, Nitish Badhwar, Mariana Albona, Mario Njeim, Melvin M. Scheinman. B-PO04-172 THE ROLE OF THE LEFT SEPTAL FASCICLE IN FASCICULAR ARRHYTHMIAS: CLINICAL PRESENTATION AND LABORATORY EVALUATION. Heart rhythm 2021. PMID:


  28. Mandla R, Jung C, Vedantham V. Transcriptional and Epigenetic Landscape of Cardiac Pacemaker Cells: Insights Into Cellular Specialization in the Sinoatrial Node. Frontiers in physiology 2021. PMID: 34335313


  29. Im SI, Voskoboinik A, Lee A, Higuchi S, Moss JD, Hsia H, Tseng ZH, Lee R, Marcus GM, Vedantham V, Scheinman M, Lee B, Park KM, Gerstenfeld EP. Predictors of long-term success after catheter ablation of premature ventricular complexes. Journal of cardiovascular electrophysiology 2021. PMID: 34041816


  30. Sanchez JM, Higuchi S, Walters TE, Vedantham V, Hsia H, Gerstenfeld EP, Badhwar N, Albona M, Njeim M, Scheinman MM. The Role of the Left Septal Fascicle in Fascicular Arrhythmias: Clinical Presentation and Laboratory Evaluation. JACC. Clinical electrophysiology 2021. PMID: 33640350


  31. Rosenthal DG, Fang CD, Groh CA, Nah G, Vittinghoff E, Dewland TA, Vedantham V, Marcus GM. Heart Failure, Atrioventricular Block, and Ventricular Tachycardia in Sarcoidosis. Journal of the American Heart Association 2021. PMID: 33599141


  32. Marcus GM, Dukes JW, Vittinghoff E, Nah G, Badhwar N, Moss JD, Lee RJ, Lee BK, Tseng ZH, Walters TE, Vedantham V, Gladstone R, Fan S, Lee E, Fang C, Ogomori K, Hue T, Olgin JE, Scheinman MM, Hsia H, Ramchandani VA, Gerstenfeld EP. A Randomized, Double-Blind, Placebo-Controlled Trial of Intravenous Alcohol to Assess Changes in Atrial Electrophysiology. JACC. Clinical electrophysiology 2021. PMID: 33516710


  33. Sung Il Im, Aleksandr Voskoboinik, Adam C Lee, satoshi higuchi, byron lee, Henry H Hsia, Joshua Moss, Vasanth Vedantham, Gregory M Marcus, zian Tseng, Randall J Lee, melvin scheinman, Edward GERSTENFELD. Abstract 12935: Predictors of Long-term Success After Catheter Ablation of Premature Ventricular Complexes. Circulation 2020. PMID:


  34. Oesterle A, Lee AC, Voskoboinik A, Moss JD, Vedantham V, Walters TE, Lee BK, Tseng ZH, Gerstenfeld EP, Scheinman MM. Electrophysiologic approach to diagnosis and ablation of patients with permanent junctional reciprocating tachycardia associated with complex anatomy and/or physiology. Journal of cardiovascular electrophysiology 2020. PMID: 33107135


  35. Galang G, Mandla R, Ruan H, Jung C, Sinha T, Stone NR, Wu RS, Mannion BJ, Allu PK, Chang K, Rammohan A, Shi MB, Pennacchio LA, Black BL, Vedantham V. ATAC-seq Reveals an Isl1 Enhancer that Regulates Sinoatrial Node Development and Function. Circulation research 2020. PMID: 33044128


  36. Matthew Bocchese, David Rosenthal, Abdullah Haddad, Benjamin Rosenfeld, Crystal Chen, Anuj Basil, Chethan Gangireddy, Joshua Cooper, Edmond Cronin, Vasanth Vedantham, Isaac Whitman, Rohit Gupta. ASSESSING RACIAL DIFFERENCE IN PULMONARY PRESSURES IN CARDIAC SARCOIDOSIS. CHEST Journal 2020. PMID:


  37. Matthew Bocchese, David Rosenthal, Abdullah Haddad, Benjamin Rosenfeld, Crystal Chen, Anuj Basil, Chethan Gangireddy, Joshua Cooper, Edmond Cronin, Vasanth Vedantham, Rohit Gupta, Isaac Whitman. PATIENT CHARACTERISTICS ASSOCIATED WITH VENTRICULAR ARRHYTHMIAS, HEART BLOCK, AND HEART FAILURE IN CARDIAC SARCOIDOSIS PATIENTS. CHEST Journal 2020. PMID:


  38. Voskoboinik A, Hadjis A, Alhede C, Im SI, Park H, Moss J, Marcus GM, Hsia H, Lee B, Tseng Z, Lee R, Scheinman M, Vedantham V, Vittinghoff E, Park KM, Gerstenfeld EP. Predictors of Adverse Outcome in Patients with Frequent Premature Ventricular Complexes: the ABC-VT Risk Score. Heart rhythm 2020. PMID: 32109563


  39. Zhang H, Ruan H, Rahmutula D, Wilson E, Marcus GM, Vedantham V, Olgin J. Effect of acute and chronic ethanol on atrial fibrillation vulnerability in rats. Heart rhythm 2019. PMID: 31756527


  40. Voskoboinik A, Hsia H, Moss J, Vedantham V, Tanel RE, Patel A, Wojciak J, Downs N, Scheinman MM. The Many Faces of Early Repolarization Syndrome:A Single Center Case-Series. Heart rhythm 2019. PMID: 31521808


  41. Rosenthal DG, Parwani P, Murray TO, Petek BJ, Benn BS, De Marco T, Gerstenfeld EP, Janmohamed M, Klein L, Lee BK, Moss JD, Scheinman MM, Hsia HH, Selby V, Koth LL, Pampaloni MH, Zikherman J, Vedantham V. Long-Term Corticosteroid-Sparing Immunosuppression for Cardiac Sarcoidosis. Journal of the American Heart Association 2019. PMID: 31538835


  42. Cardona-Guarache R, Vedantham V, Scheinman MM. Ischemia with marked ST elevation or J-wave syndrome? Journal of electrocardiology 2019. PMID: 31078103


  43. Samal E, Evangelista M, Galang G, Srivastava D, Zhao Y, Vedantham V. Premature MicroRNA-1 Expression Causes Hypoplasia of the Cardiac Ventricular Conduction System. Frontiers in physiology 2019. PMID: 30936836


  44. Szilágyi J, Walters TE, Marcus GM, Vedantham V, Moss JD, Badhwar N, Lee B, Lee R, Tseng ZH, Gerstenfeld EP. Surface ECG and intracardiac spectral measures predict atrial fibrillation recurrence after catheter ablation. Journal of cardiovascular electrophysiology 2018. PMID: 30016007


  45. Ito H, Badhwar N, Patel AR, Hoffmayer KS, Moss JD, Pellegrini CN, Vedantham V, Tseng ZH, Tanel RE, Hsia HH, Lee RJ, Marcus GM, Gerstenfeld EP, Scheinman MM. Use of Programmed Ventricular Extrastimulus During Supraventricular Tachycardia to Differentiate Atrioventricular Nodal Re-Entrant Tachycardia From Atrioventricular Re-Entrant Tachycardia. JACC. Clinical electrophysiology 2018. PMID: 30025686


  46. Guo X, Vittinghoff E, Vedantham V, Pletcher MJ, Lee BK. Trends in Hospitalizations for Cardiac Sarcoidosis in the United States, 2005-2011. Circulation journal : official journal of the Japanese Circulation Society 2017. PMID: 28904267


  47. Judit Szilágyi, Gregory M. Marcus, Nitish Badhwar, Byron K. Lee, Randall J. Lee, Vasanth Vedantham, Zian H. Tseng, Tomos Walters, Melvin Scheinman, Jeffrey Olgin, Edward P. Gerstenfeld. Cover Image, Volume 28, Issue 7. Journal of cardiovascular electrophysiology 2017. PMID:


  48. Szilágyi J, Marcus GM, Badhwar N, Lee BK, Lee RJ, Vedantham V, Tseng ZH, Walters T, Scheinman M, Olgin J, Gerstenfeld EP. Atrial fibrillation patients with isolated pulmonary veins: Is sinus rhythm achievable? Volume 28 of Issue 7. Journal of cardiovascular electrophysiology 2017. PMID: 28429499


  49. Vedantham V, Scheinman MM. Familial inappropriate sinus tachycardia: a new chapter in the story of HCN4 channelopathies. European heart journal 2017. PMID: 28182236


  50. Roberts JD, Gollob MH, Young C, Connors SP, Gray C, Wilton SB, Green MS, Zhu DW, Hodgkinson KA, Poon A, Li Q, Orr N, Tang AS, Klein GJ, Wojciak J, Campagna J, Olgin JE, Badhwar N, Vedantham V, Marcus GM, Kwok PY, Deo RC, Scheinman MM. Bundle Branch Re-Entrant Ventricular Tachycardia: Novel Genetic Mechanisms in a Life-Threatening Arrhythmia. Volume 3 of Issue 3. JACC. Clinical electrophysiology 2016. PMID: 29759522


  51. Jason D Roberts, Michael H Gollob, Charlie Young, Sean P Connors, Chris Gray, Stephen B Wilton, Martin S Green, Dennis W Zhu, Kathleen A Hodgkinson, Annie Poon, Qiuju Li, Nathan Orr, Anthony S Tang, George J Klein, Julianne Wojciak, Joan Campagna, Jeffrey E Olgin, Nitish Badhwar, Vasanth Vedantham, Gregory Marcus, Pui-Yan Kwok, Rahul C Deo, Melvin M Scheinman. Abstract 12229: Bundle Branch Reentrant Ventricular Tachycardia: Novel Genetic Mechanisms in a Life-Threatening Arrhythmia. Circulation 2016. PMID:


  52. Hiroyuki Ito, Nitish Badhwar, Akash R Patel, Ronn E Tanel, Kurt S Hoffmayer, Cara N Pellegrini, Henry H Hsia, Vasanth Vedantham, Randall J Lee, Gregory M Marcus, Edward P Gerstenfeld, Melvin M Scheinman. Abstract 12996: Use of Premature Ventricular Extrastimuli During Supraventricular Tachycardia to Differentiate Atrioventricular Nodal Reentrant Tachycardia From Atrioventricular Reentrant Tachycardia. Circulation 2016. PMID:


  53. Nguyen KT, Gladstone RA, Dukes JW, Nazer B, Vittinghoff E, Badhwar N, Vedantham V, Gerstenfeld EP, Lee BK, Lee RJ, Tseng ZH, Olgin JE, Scheinman MM, Marcus GM. The QT Interval as a Noninvasive Marker of Atrial Refractoriness. Volume 39 of Issue 12. Pacing and clinical electrophysiology : PACE 2016. PMID: 27753113


  54. Kawamura M, Scheinman MM, Vedantham V, Marcus GM, Tseng ZH, Badhwar N. Clinical and Electrophysiological Characteristics of Incessant Atrioventricular Nodal Re-Entrant Tachycardia. Volume 2 of Issue 5. JACC. Clinical electrophysiology 2016. PMID: 29759579


  55. Hiroyuki Ito, Nitish Badhwar, Mitsuharu Kawamura, Vasanth Vedantham, Zian Tseng, Byron Lee, Randall Lee, Gregory Marcus, Edward Gerstenfeld, Melvin Scheinman. POST-SHOCK ELECTROMECHANICAL DISSOCIATION DURING DEFIBRILLATION THRESHOLD TESTING. Journal of the American College of Cardiology 2016. PMID:


  56. Vedantham V. New Approaches to Biological Pacemakers: Links to Sinoatrial Node Development. Trends in molecular medicine 2015. PMID: 26611337


  57. Hoffmayer KS, Lee BK, Vedantham V, Bhimani AA, Cakulev IT, Mackall JA, Sahadevan J, Rho RW, Scheinman MM. Response to letter regarding article, "variable clinical features and ablation of manifest nodofascicular/ventricular pathways". Circulation. Arrhythmia and electrophysiology 2015. PMID: 26286312


  58. Ito H, Kawamura M, Badhwar N, Vedantham V, Tseng ZH, Lee BK, Lee RJ, Marcus GM, Gerstenfeld EP, Scheinman MM. The Effect of Direct Current Stimulation versus T-Wave Shock on Defibrillation Threshold Testing. Volume 38 of Issue 10. Pacing and clinical electrophysiology : PACE 2015. PMID: 26137999


  59. Kawamura M, Hsu JC, Vedantham V, Marcus GM, Hsia HH, Gerstenfeld EP, Scheinman MM, Badhwar N. Clinical and electrocardiographic characteristics of idiopathic ventricular arrhythmias with right bundle branch block and superior axis: Comparison of apical crux area and posterior septal left ventricle. Heart rhythm 2015. PMID: 25728755


  60. Vedantham V, Galang G, Evangelista M, Deo RC, Srivastava D. RNA sequencing of mouse sinoatrial node reveals an upstream regulatory role for Islet-1 in cardiac pacemaker cells. Circulation research 2015. PMID: 25623957


  61. Vasanth Vedantham,Jeffrey Olgin. Atrial Fibrillation. 2015. PMID:


  62. Hoffmayer KS, Lee BK, Vedantham V, Bhimani AA, Cakulev IT, Mackall JA, Sahadevan J, Rho RW, Scheinman MM. Variable clinical features and ablation of manifest nodofascicular/ventricular pathways. Circulation. Arrhythmia and electrophysiology 2014. PMID: 25472957


  63. Kawamura M, Gerstenfeld EP, Vedantham V, Rodrigues DM, Burkhardt JD, Kobayashi Y, Hsia HH, Marcus GM, Marchlinski FE, Scheinman MM, Badhwar N. Idiopathic ventricular arrhythmia originating from the cardiac crux or inferior septum: epicardial idiopathic ventricular arrhythmia. Circulation. Arrhythmia and electrophysiology 2014. PMID: 25225238


  64. Hua LL, Vedantham V, Barnes RM, Hu J, Robinson AS, Bressan M, Srivastava D, Black BL. Specification of the mouse cardiac conduction system in the absence of Endothelin signaling. Developmental biology 2014. PMID: 25050930


  65. Singh DK, Viswanathan MN, Tanel RE, Lee RJ, Lee BK, Marcus GM, Olgin JE, Han F, Vedantham V, Tseng ZH, Pellegrini C, Kawamura M, Gerstenfeld EP, Badhwar N, Scheinman M. His overdrive pacing during supraventricular tachycardia: a novel maneuver for distinguishing atrioventricular nodal reentrant tachycardia from atrioventricular reciprocating tachycardia. Volume 11 of Issue 8. Heart rhythm 2014. PMID: 24793458


  66. Kawamura M, Badhwar N, Vedantham V, Tseng ZH, Lee BK, Lee RJ, Marcus GM, Olgin JE, Gerstenfeld EP, Scheinman MM. Coupling interval dispersion and body mass index are independent predictors of idiopathic premature ventricular complex-induced cardiomyopathy. Volume 25 of Issue 7. Journal of cardiovascular electrophysiology 2014. PMID: 24612052


  67. Stepanyan G, Badhwar N, Lee RJ, Marcus GM, Lee BK, Tseng ZH, Vedantham V, Olgin J, Scheinman M, Gerstenfeld EP. Safety of new oral anticoagulants for patients undergoing atrial fibrillation ablation. Volume 40 of Issue 1. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 2014. PMID: 24643666


  68. Kawamura M, Vedantham V, Dewland TA, Scheinman MM. Incessant long RP tachycardia: what is the mechanism? Heart rhythm 2014. PMID: 24561158


  69. Hsu JC, Badhwar N, Gerstenfeld EP, Lee RJ, Mandyam MC, Dewland TA, Imburgia KE, Hoffmayer KS, Vedantham V, Lee BK, Tseng ZH, Scheinman MM, Olgin JE, Marcus GM. Randomized trial of conventional transseptal needle versus radiofrequency energy needle puncture for left atrial access (the TRAVERSE-LA study). Volume 2 of Issue 5. Journal of the American Heart Association 2013. PMID: 24045120


  70. Vedantham V, Jackman WM, Scheinman MM. Unexpected potential following ablation of a right atriofascicular accessory pathway. Journal of cardiovascular electrophysiology 2013. PMID: 23601047


  71. Frederick T. Han,Vasanth Vedantham. Narrow QRS Tachycardia with Ventriculoatrial Block. Cardiac electrophysiology clinics 2012. PMID:


  72. Vedantham V, Evangelista M, Huang Y, Srivastava D. Spatiotemporal regulation of an Hcn4 enhancer defines a role for Mef2c and HDACs in cardiac electrical patterning. Developmental biology 2012. PMID: 23085412


  73. Scheinman MM, Vedantham V. Ivabradine: a ray of hope for inappropriate sinus tachycardia. Journal of the American College of Cardiology 2012. PMID: 22981552


  74. Qian L, Huang Y, Spencer CI, Foley A, Vedantham V, Liu L, Conway SJ, Fu JD, Srivastava D. In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes. Nature 2012. PMID: 22522929


  75. Mandyam MC, Vedantham V, Scheinman MM, Tseng ZH, Badhwar N, Lee BK, Lee RJ, Gerstenfeld EP, Olgin JE, Marcus GM. Alcohol and vagal tone as triggers for paroxysmal atrial fibrillation. Volume 110 of Issue 3. The American journal of cardiology 2012. PMID: 22521307


  76. Hsu JC, Badhwar N, Lee BK, Vedantham V, Tseng ZH, Marcus GM. Predictors of fluoroscopy time and procedural failure during biventricular device implantation. Volume 110 of Issue 2. The American journal of cardiology 2012. PMID: 22483384


  77. Jonathan Hsu, Nitish Badhwar, Zian Tseng, Vasanth Vedantham, Byron Lee, Gregory Marcus. PREDICTORS OF PROCEDURAL DIFFICULTY DURING BIVENTRICULAR DEVICE IMPLANTATION: A UNIVERSITY HOSPITAL EXPERIENCE. Journal of the American College of Cardiology 2012. PMID:


  78. Vasanth Vedantham,Nitish Badhwar. Chapter 33 Current Indications for Temporary and Permanent Cardiac Pacing. 2012. PMID:


  79. Li Qian, Yu Huang, Amy Foley, Vasanth Vedantham, Ian Spencer, Simon J Conway, Jidong Fu, Deepak Srivastava. Abstract 10466: In Vivo Reprogramming of Murine Cardiac Fibroblasts into Induced Cardiomyocytes. Circulation 2011. PMID:


  80. Ieda M, Fu JD, Delgado-Olguin P, Vedantham V, Hayashi Y, Bruneau BG, Srivastava D. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell 2010. PMID: 20691899


  81. Vedantham V, Tseng ZH. Changing QRS Morphology in a Patient with Wolff-Parkinson-White Syndrome. Volume 2 of Issue 2. Cardiac electrophysiology clinics 2010. PMID: 28770758


  82. Zhao Y, Ransom JF, Li A, Vedantham V, von Drehle M, Muth AN, Tsuchihashi T, McManus MT, Schwartz RJ, Srivastava D. Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell 2007. PMID: 17397913


  83. Vedantham V, Cannon SC. Rapid and slow voltage-dependent conformational changes in segment IVS6 of voltage-gated Na(+) channels. Biophysical journal 2000. PMID: 10827974


  84. Vedantham V, Cannon SC. The position of the fast-inactivation gate during lidocaine block of voltage-gated Na+ channels. The Journal of general physiology 1999. PMID: 9874684


  85. Vedantham V, Cannon SC. Slow inactivation does not affect movement of the fast inactivation gate in voltage-gated Na+ channels. The Journal of general physiology 1998. PMID: 9417137