Uma Mahadevan, MD

Professor

Uma Mahadevan, MD
Lynne and Marc Benioff Professor of Gastroenterology
University of California, San Francisco
Director, UCSF Center for Colitis and Crohn's Disease
Website: IBD.UCSF.EDU
Twitter: @UmaMahadevanIBD

Dr. Uma Mahadevan is the Lynne and Marc Benioff Professor of Gastroenterology, Director of the Colitis and Crohn's Disease Center and Director of the Advanced IBD Fellowship at the University of California, San Francisco. She specializes in inflammatory bowel disease (IBD), particularly pregnancy and drug safety. She completed a medical degree at the State University of New York in Brooklyn, residency in internal medicine at Mount Sinai Medical Center in New York, Fellowship in gastroenterology at UCSF, and Advanced fellowship in IBD at the Mayo Clinic, Rochester, Minnesota. For her exceptional work in pregnancy and drug safety and her mentoring of GI fellows and junior faculty she received the AGA 2022 Immunology, Microbiology & Inflammatory Bowel Diseases (IMIBD) Section Research Mentor Award and the 2022 Sherman Prize.
Dr. Mahadevan is a fellow of the American Gastroenterological Association, for whom she was Chair for the IMIBD Section, Chair of the AGA National IBD Parenthood initiative and Director (2023) and co-Director (2022, 2017) of the AGA Postgraduate Course. She is a Fellow of the American College of Gastroenterology and served on the Educational Affairs Committee and as a member of the Advanced IBD Fellow Curriculum Committee. She was Chair of the Crohns Colitis Foundation Clinical Research Grants committee, a member of the National Scientific Advisory Committee and Taskforce on Women in IBD, and co-chair of the annual Crohn’s Colitis Congress (2020). Dr. Mahadevan is a member of the International Organization of IBD (IOIBD) for which she serves on the nominating committee.
Dr. Mahadevan has served on many prestigious journals, including special section editor for Gastroenterology. Dr. Mahadevan has published over 100 original articles, abstracts, editorials, and invited reviews in such peer-reviewed journals as Gastroenterology, Gut, Nature Reviews, American Journal of Gastroenterology, Inflammatory Bowel Diseases, and Lancet Gastroenterology Hepatology as well as several book chapters. She authored the joint AGA, Society of Maternal Fetal Medicine Clinical Care Pathway on the Management of IBD in Pregnancy.
Dr. Mahadevan is a global expert on the management of pregnancy and drug safety in the patient with IBD. She is also interested in the role of diet and IBD and has an ongoing original study in this area. Her current projects include a national prospective registry of pregnancy outcomes and drug safety in women with IBD on immunosuppressive and biologic medications (PIANO) and a clinical trial on the impact of nutritional interventions in the management of IBD (SEAMUS). She has an interest in digital health and lead the transition of the GI Division to telemedicine at the start of the pandemic in March 2020 and has developed an IBD Chatbot with the Center for Digital Health and Innovation at UCSF. Dr. Mahadevan is proud to have mentored several Advanced IBD Fellows who know hold key roles in IBD Centers around the United States.

Education
Inflammatory Bowel Disease, 2001 - , Mayo Clinic, Rochester, MN
Gastroenterology, 2001 - , University of California, San Francisco
Internal Medicine, 1998 - , Mount Sinai School of Medicine
M.D., 1995 - , SUNY Brooklyn
Honors and Awards
  • IMIBD Research Mentor Award, American Gastroenterology Association, 2022
  • Sherman Prize: Innovator for Life, Bruce and Cynthia Sherman Foundation, 2022
  • Catalyst for Mission Advancement, Crohn's Colitis Foundation, Bay Area, 2021
  • Innovator Award, Crohn's Colitis Foundation, 2020
  • Best Doctors in America/ San Francisco, Castle Connelly, 2008-2023
Websites
Publications

  1. Ear S, Cordero J, McConnell R, Velayos F, Mahadevan U, Lewin S. Extended Monitoring for Transition to Oral Corticosteroids in Acute Severe Ulcerative Colitis May Be Unnecessarily Prolonging Length of Stay. Digestive diseases and sciences 2024. PMID: 39495414


  2. Mahadevan U, Long M. Low Placental Transfer Rates of Risankizumab Among Pregnant Women With Inflammatory Bowel Disease. Inflammatory bowel diseases 2024. PMID: 39216079


  3. Memel Z, Thiemann A, Dort C, Mahadevan U, Beck KR. Prevalence of Malnutrition and Micronutrient Deficiencies in Older Adults with Ulcerative Colitis. Digestive diseases and sciences 2024. PMID: 39438412


  4. ASGE IBD Endoscopy Consensus Panel, Shen B, Abreu MT, Cohen ER, Farraye FA, Fischer M, Feuerstadt P, Kapur S, Ko HM, Kochhar GS, Liu X, Mahadevan U, McBride DL, Navaneethan U, Regueiro M, Ritter T, Sharma P, Lichtenstein GR. Endoscopic diagnosis and management of adult inflammatory bowel disease: a consensus document from the American Society for Gastrointestinal Endoscopy IBD Endoscopy Consensus Panel. Gastrointestinal endoscopy 2024. PMID: 39425706


  5. Field J, Fenton C, Zhang L, Brickman C, Mahadevan U. Inflammatory Bowel Disease and the Risk of Anal Squamous Intraepithelial Lesions and Anal Cancer in Men Who Have Sex With Men. Inflammatory bowel diseases 2023. PMID: 37951596


  6. Karlovich N, McConnell R, Velayos F, Mahadevan U, Lewin S. Opioid Use and Outcomes in Patients Hospitalized With Acute Severe Ulcerative Colitis. Inflammatory bowel diseases 2024. PMID: 39295282


  7. Mahadevan U, Levy G, Gensler L, Ali M, Lacerda AP, Wegrzyn L, Palac H, Bhutani-Jacques T, Long M, Clowse MEB, Kimball AB, Chambers C, Scialli AR. Pregnancy Outcomes in Patients Treated with Upadacitinib: Analysis of Data from Clinical Trials and Postmarketing Reports. Drug safety 2024. PMID: 39008024


  8. Torres J, Mahadevan U. Editorial: Ustekinumab and Vedolizumab Safety and Clearance in Pregnancy with Inflammatory Bowel Disease: Stop the Disease, not the Drug! Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2024. PMID: 38878846


  9. Field J, Shah ND, Memel Z, Mahadevan U, Beck K. Exclusive Yet Effective: The Crohn's Disease Exclusion Diet as Treatment for Medication-Refractory Disease. Digestive diseases and sciences 2024. PMID: 38555328


  10. Mahadevan U, Dubinsky M, Dotan I. Our New President-Maria T. Abreu, MD, AGAF. Gastroenterology 2024. PMID: 38456870


  11. Mennillo E, Kim YJ, Lee G, Rusu I, Patel RK, Dorman LC, Flynn E, Li S, Bain JL, Andersen C, Rao A, Tamaki S, Tsui J, Shen A, Lotstein ML, Rahim M, Naser M, Bernard-Vazquez F, Eckalbar W, Cho SJ, Beck K, El-Nachef N, Lewin S, Selvig DR, Terdiman JP, Mahadevan U, Oh DY, Fragiadakis GK, Pisco A, Combes AJ, Kattah MG. Single-cell and spatial multi-omics highlight effects of anti-integrin therapy across cellular compartments in ulcerative colitis. Nature communications 2024. PMID: 38374043


  12. Mitrova K, Julsgaard M, Augustijns P, Cerna K, Mahadevan U, Duricova D, Pregnancy study group. Tofacitinib in pregnancy: Assessing Pregnancy and Infant Outcomes, Cord Blood and Breast Milk Concentrations. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2024. PMID: 38309493


  13. Dubinsky MC, Charles L, Selmaj KW, Comi G, Krakovich A, Rosen M, van der Woude CJ, Mahadevan U. Pregnancy Outcomes in the Ozanimod Clinical Development Program in Patients With Ulcerative Colitis, Crohn's Disease, and Relapsing Multiple Sclerosis. Inflammatory bowel diseases 2024. PMID: 38267826


  14. Odufalu FD, Sewell JL, Rudrapatna V, Somsouk M, Mahadevan U. Assessing the Impact of COVID-19 on IBD Outcomes Among Vulnerable Patient Populations in a Large Metropolitan Center. Inflammatory bowel diseases 2023. PMID: 36943305


  15. Mennillo E, Kim YJ, Rusu I, Lee G, Dorman LC, Bernard-Vazquez F, Bain JL, Patel R, Andersen C, Rao A, Tamaki S, Tsui J, Shen A, Naser M, Eckalbar W, Cho SJ, Beck K, El-Nachef N, Lewin S, Selvig DR, Terdiman JP, Mahadevan U, Oh DY, Fragiadakis GK, Pisco A, Combes AJ, Kattah MG. Single-cell and spatial multi-omics identify innate and stromal modules targeted by anti-integrin therapy in ulcerative colitis. bioRxiv : the preprint server for biology 2023. PMID: 36711576


  16. Chugh R, Long MD, Jiang Y, Weaver KN, Beaulieu DB, Scherl EJ, Mahadevan U. Maternal and Neonatal Outcomes in Vedolizumab and Ustekinumab Exposed Pregnancies: Results from the PIANO registry. The American journal of gastroenterology 2023. PMID: 37796648


  17. Chugh R, Liu AW, Idomsky Y, Bigazzi O, Maiorano A, Medina E, Pierce L, Odisho A, Mahadevan U. A Digital Health Intervention to Improve the Clinical Care of Inflammatory Bowel Disease Patients. Applied clinical informatics 2023. PMID: 37586416


  18. Julsgaard M, Mahadevan U, Vestergaard T, Mols R, Ferrante M, Augustijns P. Tofacitinib concentrations in plasma and breastmilk of a lactating woman with ulcerative colitis. The lancet. Gastroenterology & hepatology 2023. PMID: 37269871


  19. Yu A, Ha NB, Shi B, Cheng YW, Mahadevan U, Beck KR. Real-World Experience with Tofacitinib Dose De-escalation in Patients with Moderate and Severe Ulcerative Colitis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2023. PMID: 37187323


  20. Chugh R, Braga-Neto MB, Fredrick TW, Ramos GP, Terdiman J, El-Nachef N, Loftus EV, Mahadevan U, Kane SV. Multicenter Real-world Experience of Upadacitinib in the Treatment of Crohn's Disease. Journal of Crohn's & colitis 2022. PMID: 36272109


  21. Brondfield MN, Mahadevan U. Inflammatory bowel disease in pregnancy and breastfeeding. Nature reviews. Gastroenterology & hepatology 2023. PMID: 37002407


  22. Rudrapatna VA, Cheng YW, Feuille C, Mosenia A, Shih J, Shi Y, Roberson O, Rubin B, Butte AJ, Mahadevan U, Skomrock N, Erondu N, Chehoud C, Rahim S, Apfel D, Curran M, Khan NS, O'Brien C, Terry N, Martini BD. Creation of an ustekinumab external control arm for Crohn's disease using electronic health records data: A pilot study. PloS one 2023. PMID: 36862717


  23. Hansel S, Muthusamy VR, Mahadevan U. 1TIPS AND TRICKS: STARTING YOUR OWN CONTINUING MEDICAL EDUCATION COURSE. Gastroenterology 2023. PMID: 36736705


  24. Singh S, Kim J, Luo J, Paul P, Rudrapatna V, Park S, Zheng K, Syal G, Ha C, Fleshner P, McGovern D, Sauk JS, Limketkai B, Dulai PS, Boland BS, Eisenstein S, Ramamoorthy S, Melmed G, Mahadevan U, Sandborn WJ, Ohno-Machado L. Comparative Safety and Effectiveness of Biologic Therapy for Crohn's Disease: A CA-IBD Cohort Study. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2022. PMID: 36343846


  25. Blaisdell A, Zhou Y, Kattah MG, Fisher SJ, Mahadevan U. Vedolizumab Antagonizes MAdCAM-1-Dependent Human Placental Cytotrophoblast Adhesion and Invasion In Vitro. 2022. PMID: 35349682


  26. Chugh R, Mahadevan U. Advanced Fellowship Training in IBD: A Worthwhile Fourth Year. Digestive diseases and sciences 2022. PMID: 35879514


  27. Gu P, Luo J, Kim J, Paul P, Limketkai B, Sauk JS, Park S, Parekh N, Zheng K, Rudrapatna V, Syal G, Ha C, McGovern DP, Melmed GY, Fleshner P, Eisenstein S, Ramamoorthy S, Dulai PS, Boland BS, Grunvald E, Mahadevan U, Ohno-Machado L, Sandborn WJ, Singh S. Effect of Obesity on Risk of Hospitalization, Surgery, and Serious Infection in Biologic-Treated Patients With Inflammatory Bowel Diseases: A CA-IBD Cohort Study. The American journal of gastroenterology 2022. PMID: 35973139


  28. Mahadevan U, Abraham NS, Lennon AM, Charabaty A, Vermeire S. Closing the gender gap: building a successful career and leadership in research as a female gastroenterologist. 2022. PMID: 35550046


  29. Nguyen NH, Luo J, Paul P, Kim J, Syal G, Ha C, Rudrapatna V, Park S, Parekh N, Zheng K, Sauk J, Limketkai B, Fleshner P, Eisenstein S, Ramamoorthy S, Melmed G, Dulai P, Boland B, Mahadevan U, Sandborn WJ, Ohno-Machado L, McGovern D, Singh S. Unplanned healthcare utilization and safety of biologic therapy in Hispanic vs. non-Hispanic patients with IBD: A CA-IBD Cohort Study. 2022. PMID: 35644340


  30. Mahadevan U, Naureckas S, Tikhonov I, Wang Y, Lin CB, Geldhof A, van der Woude CJ. Pregnancy outcomes following periconceptional or gestational exposure to ustekinumab: Review of cases reported to the manufacturer's global safety database. 2022. PMID: 35560249


  31. Caplan A, McConnell R, Velayos F, Mahadevan U, Lewin S. Delayed Initiation of Rescue Therapy Associated with Increased Length of Stay in Acute Severe Ulcerative Colitis. 2022. PMID: 35389167


  32. Mahadevan U. Performing Surveillance Endoscopy for Patients with Inflammatory Bowel Disease. 2022. PMID: 35032482


  33. Kushner T, Fairchild A, Johnson FR, Sands BE, Mahadevan U, Subramanian S, Ananthakrishnan A, Ha C, Bewtra M. Women's Willingness to Accept Risks of Medication for Inflammatory Bowel Disease During Pregnancy. 2021. PMID: 34750784


  34. Odufalu FD, Long M, Lin K, Mahadevan U, PIANO Investigators from the Crohn’s and Colitis Foundation (CCF) Clinical Research Alliance recruit. Exposure to corticosteroids in pregnancy is associated with adverse perinatal outcomes among infants of mothers with inflammatory bowel disease: results from the PIANO registry. 2021. PMID: 34686575


  35. Cronin M, Berger TG, Cohen SH, Mahadevan U, North JP, Asch S. Cutaneous Chaetomium globosum Infection in a Vedolizumab-Treated Patient. 2021. PMID: 34735323


  36. Holubar SD, Lightner AL, Poylin V, Vogel JD, Gaertner W, Davis B, Davis KG, Mahadevan U, Shah SA, Kane SV, Steele SR, Paquette IM, Feingold DL, Prepared on behalf of the Clinical Practice Guidelines Committee of the American Society of Colon an. The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Surgical Management of Ulcerative Colitis. Diseases of the colon and rectum 2021. PMID: 33853087


  37. Roy Paladhi U, Harb AH, Daniel SG, Dawwas GK, Schnellinger EM, Wollack C, Aberra FN, Bewtra M, Green JA, Klaproth JA, Lichtenstein GR, Saxena A, Berera S, Buchner A, Mehta SJ, Osterman MT, Rashid F, Tomov V, Caldera F, Sumona S, Mahadevan U, Roy A, Nessel L, Wu GD, Bittinger K, Lewis JD. The Impact of Introducing Patient-Reported Inflammatory Bowel Disease Symptoms via Electronic Survey on Clinic Visit Length, Patient and Provider Satisfaction, and the Environment Microbiome. Inflammatory bowel diseases 2021. PMID: 33452800


  38. Meserve J, Luo J, Zhu W, Veeravalli N, Bandoli G, Chambers CD, Singh AG, Boland BS, Sandborn WJ, Mahadevan U, Singh S. Paternal Exposure to Immunosuppressive and/or Biologic Agents and Birth Outcomes in Patients With Immune-Mediated Inflammatory Diseases. Gastroenterology 2021. PMID: 33744307


  39. Long MD, Siegel CA, Abraham BP, Chiorean M, Mahadevan U. Day Care Attendance and Infectious Complications in Children Born to Mothers With Inflammatory Bowel Disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2021. PMID: 33549864


  40. Mahadevan U. Overview of Pregnancy in Patients With Inflammatory Bowel Disease. Gastroenterology & hepatology 2021. PMID: 34035766


  41. Mahadevan U, Long MD, Kane SV, Roy A, Dubinsky MC, Sands BE, Cohen RD, Chambers CD, Sandborn WJ, Crohn’s Colitis Foundation Clinical Research Alliance. Pregnancy and Neonatal Outcomes After Fetal Exposure to Biologics and Thiopurines Among Women With Inflammatory Bowel Disease. Gastroenterology 2020. PMID: 33227283


  42. Lewin S, Lees C, Regueiro M, Hart A, Mahadevan U. International Organization for the Study of Inflammatory Bowel Disease: Global Strategies for Telemedicine and Inflammatory Bowel Diseases. Journal of Crohn's & colitis 2020. PMID: 33085971


  43. Nuñez F P, Mahadevan U, Quera R, Bay C, Ibañez P. Treat-to-target approach in the management of inflammatory Bowel disease. Gastroenterologia y hepatologia 2020. PMID: 33070988


  44. Regner EH, Green AJ, Bain JL, Kattah MG, Mahadevan U. Importance of Not MSing Cerebral White Matter Disease in Patients with Inflammatory Bowel Disease. Digestive diseases and sciences 2020. PMID: 32651742


  45. Cohen BL, Gallinger ZR, Ha C, Holubar SD, Hou JK, Kinnucan J, Mahadevan U, Moss AC, Raffals LE, Regueiro M, Szigethy E, Wolf D, Dubinsky MC, Patel A, Shah BJ, Ehrlich OG, Hanauer SB. Development of Entrustable Professional Activities for Advanced Inflammatory Bowel Disease Fellowship Training in the United States. Inflammatory bowel diseases 2020. PMID: 32820340


  46. Lightner AL, Vogel JD, Carmichael JC, Keller DS, Shah SA, Mahadevan U, Kane SV, Paquette IM, Steele SR, Feingold DL. The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Surgical Management of Crohn's Disease. Diseases of the colon and rectum 2020. PMID: 32692069


  47. Lees CW, Regueiro M, Mahadevan U. Innovation in IBD Care During the COVID-19 Pandemic: Results of a Global Telemedicine Survey by the International Organization for the Study of Inflammatory Bowel Disease. Gastroenterology 2020. PMID: 32474119


  48. LaHue SC, Anderson A, Krysko KM, Rutatangwa A, Dorsey MJ, Hale T, Mahadevan U, Rogers EE, Rosenstein MG, Bove R. Transfer of monoclonal antibodies into breastmilk in neurologic and non-neurologic diseases. Neurology(R) neuroimmunology & neuroinflammation 2020. PMID: 32461351


  49. Hammami MB, Mahadevan U. Men With Inflammatory Bowel Disease: Sexual Function, Fertility, Medication Safety, and Prostate Cancer. The American journal of gastroenterology 2020. PMID: 32022719


  50. Levine A, Rhodes JM, Lindsay JO, Abreu MT, Kamm MA, Gibson PR, Gasche C, Silverberg MS, Mahadevan U, Sigall Boneh R, Wine E, Damas OM, Syme G, Trakman GL, Yao CK, Stockhamer SI, Hammami MB, Garces LC, Rogler G, Koutroubakis IE, Ananthakrishnan A, Liam M, Lewis JD. Dietary Guidance for Patients with Inflammatory Bowel Disease from the International Organization for the Study of Inflammatory Bowel Disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2020. PMID: 32068150


  51. Ko MS, Rudrapatna VA, Avila P, Mahadevan U. Safety of Flexible Sigmoidoscopy in Pregnant Patients with Known or Suspected Inflammatory Bowel Disease. Digestive diseases and sciences 2020. PMID: 32034603


  52. Lim J, Hammami MB, Mahadevan U. Infliximab Use in a Child with Ulcerative Colitis and Prior in utero Exposure to Infliximab. Gastroenterology 2020. PMID: 31926172


  53. Mahadevan U, Robinson C, Bernasko N, Boland B, Chambers C, Dubinsky M, Friedman S, Kane S, Manthey J, Sauberan J, Stone J, Jain R. Erratum: Inflammatory Bowel Disease in Pregnancy Clinical Care Pathway: A Report From the American Gastroenterological Association IBD Parenthood Project Working Group. Inflammatory bowel diseases 2019. PMID: 30947328


  54. Lewin SM, McConnell RA, Patel R, Sharpton SR, Velayos F, Mahadevan U. Improving the Quality of Inpatient Ulcerative Colitis Management: Promoting Evidence-Based Practice and Reducing Care Variation With an Inpatient Protocol. Inflammatory bowel diseases 2019. PMID: 30980712


  55. Mahadevan U, Fisher S, Riley L, Chambers C, Jain R, Robinson C. Reply to GASTRO-D-19-00915. Gastroenterology 2019. PMID: 31513796


  56. Scott FI, Rubin DT, Kugathasan S, Bousvaros A, Elson CO, Newberry RD, Melmed GY, Pekow J, Fleshman JW, Boyle BM, Mahadevan U, Cannon LM, Long MD, Cross RK, Ha CY, Lasch KL, Robinson AM, Rafferty JF, Lee JJ, Dahl KDC, Weaver A, Shtraizent N, Honig G, Hurtado-Lorenzo A, Heller CA. Challenges in IBD Research: Pragmatic Clinical Research. Inflammatory bowel diseases 2019. PMID: 31095704


  57. Mahadevan U, Robinson C, Bernasko N, Boland B, Chambers C, Dubinsky M, Friedman S, Kane S, Manthey J, Sauberan J, Stone J, Jain R. Inflammatory Bowel Disease in Pregnancy Clinical Care Pathway: A Report From the American Gastroenterological Association IBD Parenthood Project Working Group. American journal of obstetrics and gynecology 2019. PMID: 30948039


  58. Mahadevan U, Robinson C, Bernasko N, Boland B, Chambers C, Dubinsky M, Friedman S, Kane S, Manthey J, Sauberan J, Stone J, Jain R. Inflammatory Bowel Disease in Pregnancy Clinical Care Pathway: A Report From the American Gastroenterological Association IBD Parenthood Project Working Group. Inflammatory bowel diseases 2019. PMID: 30821832


  59. Mao EJ, Sheibani S, Martin C, Bloomfeld RS, Isaacs K, Saha S, Mahadevan U. Preventive Health Care Among Postpartum Women With Inflammatory Bowel Disease: Results From the PIANO Registry. Inflammatory bowel diseases 2019. PMID: 30256951


  60. Hammami MB, Gill R, Thiruvengadam N, Oh DY, Beck K, Mahadevan U, Kattah MG. Balancing the Checkpoint: Managing Colitis Associated with Dual Checkpoint Inhibitors and High-Dose Aspirin. Digestive diseases and sciences 2019. PMID: 30778872


  61. Mahadevan U, Robinson C, Bernasko N, Boland B, Chambers C, Dubinsky M, Friedman S, Kane S, Manthey J, Sauberan J, Stone J, Jain R. Inflammatory Bowel Disease in Pregnancy Clinical Care Pathway: A Report From the American Gastroenterological Association IBD Parenthood Project Working Group. Gastroenterology 2019. PMID: 30658060


  62. Lewin SM, Wen KW, Velayos FS, Mahadevan U, Beck KR. How Dye May Prevent Dying from Cancer: Perceiving Imperceptible Dysplasia in Inflammatory Bowel Disease. Digestive diseases and sciences 2019. PMID: 30523483


  63. Mahadevan U, Dubinsky MC, Su C, Lawendy N, Jones TV, Marren A, Zhang H, Graham D, Clowse MEB, Feldman SR, Baumgart DC. Outcomes of Pregnancies With Maternal/Paternal Exposure in the Tofacitinib Safety Databases for Ulcerative Colitis. Inflammatory bowel diseases 2018. PMID: 29982686


  64. Mao EJ, Mahadevan U. The Debate is Over: Continue Anti-Tumor Necrosis Factor Therapy Throughout Pregnancy. The American journal of gastroenterology 2018. PMID: 30337704


  65. Mahadevan U, Vermeire S, Lasch K, Abhyankar B, Bhayat F, Blake A, Dubinsky M. Letter: vedolizumab drug levels in cord and maternal blood in women with inflammatory bowel disease-authors' reply. Alimentary pharmacology & therapeutics 2018. PMID: 29998501


  66. Kattah MG, Milush JM, Burt T, McCabe RP, Whang MI, Ma A, Mahadevan U. Correction: Anti-TNF and thiopurine therapy in pregnant IBD patients does not significantly alter a panel of B-cell and T-cell subsets in 1-year-old infants. Clinical and translational gastroenterology 2018. PMID: 30065242


  67. Lichtenstein GR, Feagan BG, Mahadevan U, Salzberg BA, Langholff W, Morgan JG, Safdi M, Nissinen R, Taillard F, Sandborn WJ, Cohen RD. Pregnancy Outcomes Reported During the 13-Year TREAT Registry: A Descriptive Report. The American journal of gastroenterology 2018. PMID: 30022113


  68. Matro R, Martin CF, Wolf D, Shah SA, Mahadevan U. Exposure Concentrations of Infants Breastfed by Women Receiving Biologic Therapies for Inflammatory Bowel Diseases and Effects of Breastfeeding on Infections and Development. Gastroenterology 2018. PMID: 29857090


  69. Kattah MG, Milush JM, Burt T, McCabe RP, Whang MI, Ma A, Mahadevan U. Anti-TNF and thiopurine therapy in pregnant IBD patients does not significantly alter a panel of B-cell and T-cell subsets in 1-year-old infants. Clinical and translational gastroenterology 2018. PMID: 29618720


  70. Mahadevan U, Silverberg MS. Inflammatory Bowel Disease-Gastroenterology Diamond Jubilee Review. Gastroenterology 2018. PMID: 29550591


  71. Beaulieu DB, Ananthakrishnan AN, Martin C, Cohen RD, Kane SV, Mahadevan U. Use of Biologic Therapy by Pregnant Women With Inflammatory Bowel Disease Does Not Affect Infant Response to Vaccines. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2017. PMID: 28870657


  72. Bengtson MB, Aamodt G, Mahadevan U, Vatn MH. Inadequate Gestational Weight Gain, the Hidden Link Between Maternal IBD and Adverse Pregnancy Outcomes: Results from the Norwegian Mother and Child Cohort Study. Inflammatory bowel diseases 2017. PMID: 28452861


  73. Mahadevan U, Vermeire S, Lasch K, Abhyankar B, Bhayat F, Blake A, Dubinsky M. Editorial: vedolizumab in pregnancy - is gut selectivity as good for baby as it is for mum? Authors' reply. Alimentary pharmacology & therapeutics 2017. PMID: 28370036


  74. Mahadevan U. How to Get an Education in Inflammatory Bowel Disease During Fellowship: Expectations and Realities. Gastroenterology 2017. PMID: 28461195


  75. Bengtson MB, Martin CF, Aamodt G, Vatn MH, Mahadevan U. Inadequate Gestational Weight Gain Predicts Adverse Pregnancy Outcomes in Mothers with Inflammatory Bowel Disease: Results from a Prospective US Pregnancy Cohort. Digestive diseases and sciences 2017. PMID: 28332106


  76. Mahadevan U, Vermeire S, Lasch K, Abhyankar B, Bhayat F, Blake A, Dubinsky M. Vedolizumab exposure in pregnancy: outcomes from clinical studies in inflammatory bowel disease. Alimentary pharmacology & therapeutics 2017. PMID: 28169436


  77. Colombel JF, Mahadevan U. Inflammatory Bowel Disease 2017: Innovations and Changing Paradigms. Gastroenterology 2016. PMID: 27960091


  78. Mahadevan U, McConnell RA, Chambers CD. Drug Safety and Risk of Adverse Outcomes for Pregnant Patients With Inflammatory Bowel Disease. Gastroenterology 2016. PMID: 27769809


  79. Mar JS, LaMere BJ, Lin DL, Levan S, Nazareth M, Mahadevan U, Lynch SV. Disease Severity and Immune Activity Relate to Distinct Interkingdom Gut Microbiome States in Ethnically Distinct Ulcerative Colitis Patients. Volume 7 of Issue 4. mBio 2016. PMID: 27531910


  80. McConnell RA, Mahadevan U. The Birds, the Bees, and Inflammatory Bowel Disease: Preconception Care in Inflammatory Bowel Disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2016. PMID: 27264392


  81. Cohan JN, Ozanne EM, Sewell JL, Hofer RK, Mahadevan U, Varma MG, Finlayson E. A Novel Decision Aid for Surgical Patients with Ulcerative Colitis: Results of a Pilot Study. Volume 59 of Issue 6. Diseases of the colon and rectum 2016. PMID: 27145309


  82. McConnell RA, Mahadevan U. Pregnancy and the Patient with Inflammatory Bowel Disease: Fertility, Treatment, Delivery, and Complications. Gastroenterology clinics of North America 2016. PMID: 27261899


  83. Kathpalia P, Kane S, Mahadevan U. Detectable Drug Levels in Infants Exposed to Biologics: So What? Gastroenterology 2016. PMID: 27215654


  84. Carlucci JG, Halasa N, Creech CB, Dulek DE, Gómez-Duarte OG, Nelson GE, Talbot HK, Scalise ML, Scott PL, Mahadevan U, Beaulieu DB. Vertical Transmission of Histoplasmosis Associated With Anti-Tumor Necrosis Factor Therapy. Journal of the Pediatric Infectious Diseases Society 2016. PMID: 27012275


  85. Sheibani S, Cohen R, Kane S, Dubinsky M, Church JA, Mahadevan U. The Effect of Maternal Peripartum Anti-TNFa Use on Infant Immune Response. Digestive diseases and sciences 2016. PMID: 26725061


  86. McConnell RA, Mahadevan U. Use of Immunomodulators and Biologics Before, During, and After Pregnancy. Inflammatory bowel diseases 2016. PMID: 26444103


  87. Nguyen GC, Seow CH, Maxwell C, Huang V, Leung Y, Jones J, Leontiadis GI, Tse F, Mahadevan U, van der Woude CJ. The Toronto Consensus Statements for the Management of Inflammatory Bowel Disease in Pregnancy. Gastroenterology 2015. PMID: 26688268


  88. Mahadevan U, Matro R. In Reply. Obstetrics and gynecology 2015. PMID: 26488508


  89. Clowse ME, Wolf DC, Förger F, Cush JJ, Golembesky A, Shaughnessy L, De Cuyper D, Mahadevan U. Pregnancy Outcomes in Subjects Exposed to Certolizumab Pegol. The Journal of rheumatology 2015. PMID: 26523031


  90. Mahadevan U, Matro R. Care of the Pregnant Patient With Inflammatory Bowel Disease. Obstetrics and gynecology 2015. PMID: 26241432


  91. Kattah MG, Mahadevan U. Confocal laser endomicroscopy for membrane-bound tumor necrosis factor predicts response to therapy in Crohn's disease. Gastroenterology 2015. PMID: 25824357


  92. Kavanaugh A, Cush JJ, Ahmed MS, Bermas BL, Chakravarty E, Chambers C, Clowse M, Curtis JR, Dao K, Hankins GD, Koren G, Kim SC, Lapteva L, Mahadevan U, Moore T, Nolan M, Ren Z, Sammaritano LR, Seymour S, Weisman MH. Proceedings from the American College of Rheumatology Reproductive Health Summit: the management of fertility, pregnancy, and lactation in women with autoimmune and systemic inflammatory diseases. Arthritis care & research 2015. PMID: 25385050


  93. Matro R, Mahadevan U. Editorial: the management of IBD during pregnancy and lactation. Alimentary pharmacology & therapeutics 2014. PMID: 25303380


  94. Huang VW, Mahadevan U. A measured approach to Crohn's therapy: check levels and save. Gastroenterology 2014. PMID: 25240163


  95. Lin K, Mahadevan U. Pharmacokinetics of biologics and the role of therapeutic monitoring. Gastroenterology clinics of North America 2014. PMID: 25110259


  96. Kattah MG, Mahadevan U. Insights into the molecular pathophysiology of inflammatory bowel disease: ATG16L1 suppresses nod-driven inflammation. Gastroenterology 2014. PMID: 24953625


  97. Hassid B, Mahadevan U. The use of biologic therapy in pregnancy: a gastroenterologist's perspective. Current opinion in rheumatology 2014. PMID: 24625373


  98. Hwang C, Ross V, Mahadevan U. Popular exclusionary diets for inflammatory bowel disease: the search for a dietary culprit. Inflammatory bowel diseases 2014. PMID: 24562173


  99. Shah S, Terdiman J, Gundling K, Mahadevan U. Immunoglobulin therapy for refractory Crohn's disease. Therapeutic advances in gastroenterology 2014. PMID: 24587823


  100. Ng SW, Mahadevan U. My treatment approach to management of the pregnant patient with inflammatory bowel disease. Mayo Clinic proceedings 2014. PMID: 24582194


  101. Lin KK, Mahadevan U. Etrolizumab: anti-ß7-a novel therapy for ulcerative colitis. Gastroenterology 2013. PMID: 24269566


  102. Truta B, Li DX, Mahadevan U, Fisher ER, Chen YY, Grace K, Velayos F, Terdiman JP. Serologic markers associated with development of Crohn's disease after ileal pouch anal anastomosis for ulcerative colitis. Digestive diseases and sciences 2013. PMID: 24091907


  103. Sheibani S, Mahadevan U. Editorial: Are thiopurines and anti-TNFa agents safe to use in pregnant patients with inflammatory bowel disease? The American journal of gastroenterology 2013. PMID: 23459048


  104. Ng SW, Mahadevan U. Management of inflammatory bowel disease in pregnancy. Expert review of clinical immunology 2013. PMID: 23390947


  105. Akbari M, Shah S, Velayos FS, Mahadevan U, Cheifetz AS. Systematic review and meta-analysis on the effects of thiopurines on birth outcomes from female and male patients with inflammatory bowel disease. Inflammatory bowel diseases 2013. PMID: 22434610


  106. Mahadevan U, Wolf DC, Dubinsky M, Cortot A, Lee SD, Siegel CA, Ullman T, Glover S, Valentine JF, Rubin DT, Miller J, Abreu MT. Placental transfer of anti-tumor necrosis factor agents in pregnant patients with inflammatory bowel disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2012. PMID: 23200982


  107. Pak S, Holland N, Garnett EA, Mileti E, Mahadevan U, Beckert R, Kanwar B, Heyman MB. Cytokine profiles in peripheral blood of children and adults with Crohn disease. Volume 54 of Issue 6. Journal of pediatric gastroenterology and nutrition 2012. PMID: 22167015


  108. Hwang C, Ross V, Mahadevan U. Micronutrient deficiencies in inflammatory bowel disease: from A to zinc. Inflammatory bowel diseases 2012. PMID: 22488830


  109. Esteve M, Mahadevan U, Sainz E, Rodriguez E, Salas A, Fernández-Bañares F. Efficacy of anti-TNF therapies in refractory severe microscopic colitis. Journal of Crohn's & colitis 2011. PMID: 22115383


  110. Leung Y, Heyman MB, Mahadevan U. Transitioning the adolescent inflammatory bowel disease patient: guidelines for the adult and pediatric gastroenterologist. Volume 17 of Issue 10. Inflammatory bowel diseases 2010. PMID: 21910179


  111. Mahadevan U, Cucchiara S, Hyams JS, Steinwurz F, Nuti F, Travis SP, Sandborn WJ, Colombel JF. The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organisation: pregnancy and pediatrics. The American journal of gastroenterology 2010. PMID: 21157441


  112. Broadhurst MJ, Leung JM, Kashyap V, McCune JM, Mahadevan U, McKerrow JH, Loke P. IL-22+ CD4+ T cells are associated with therapeutic trichuris trichiura infection in an ulcerative colitis patient. Science translational medicine 2010. PMID: 21123809


  113. van der Woude CJ, Kolacek S, Dotan I, Oresland T, Vermeire S, Munkholm P, Mahadevan U, Mackillop L, Dignass A. European evidenced-based consensus on reproduction in inflammatory bowel disease. Journal of Crohn's & colitis 2010. PMID: 21122553


  114. Kwan LY, Mahadevan U. Inflammatory bowel disease and pregnancy: an update. Expert review of clinical immunology 2010. PMID: 20594137


  115. Dotan I, Rachmilewitz D, Schreiber S, Eliakim R, van der Woude CJ, Kornbluth A, Buchman AL, Bar-Meir S, Bokemeyer B, Goldin E, Maaser C, Mahadevan U, Seidler U, Hoffman JC, Homoky D, Plasse T, Powers B, Rutgeerts P, Hommes D. A randomised placebo-controlled multicentre trial of intravenous semapimod HCl for moderate to severe Crohn's disease. Gut 2010. PMID: 20551461


  116. Hou JK, Velayos F, Terrault N, Mahadevan U. Viral hepatitis and inflammatory bowel disease. Inflammatory bowel diseases 2010. PMID: 20480515


  117. El-Nachef N, Terdiman J, Mahadevan U. Anti-tumor necrosis factor therapy for inflammatory bowel disease in the setting of immunosuppression for solid organ transplantation. The American journal of gastroenterology 2010. PMID: 20445523


  118. Baumgart DC, Targan SR, Dignass AU, Mayer L, van Assche G, Hommes DW, Hanauer SB, Mahadevan U, Reinisch W, Plevy SE, Salzberg BA, Buchman AL, Mechkov GM, Krastev ZA, Lowder JN, Frankel MB, Sandborn WJ. Prospective randomized open-label multicenter phase I/II dose escalation trial of visilizumab (HuM291) in severe steroid-refractory ulcerative colitis. Inflammatory bowel diseases 2010. PMID: 19714757


  119. Molloy JW, Kim E, Mahadevan U. Do side-by-side anastomoses decrease the risk of recurrence in Crohn's disease? Gastroenterology 2010. PMID: 20303965


  120. Sandborn WJ, Korzenik J, Lashner B, Leighton JA, Mahadevan U, Marion JF, Safdi M, Sninsky CA, Patel RM, Friedenberg KA, Dunnmon P, Ramsey D, Kane S. Once-daily dosing of delayed-release oral mesalamine (400-mg tablet) is as effective as twice-daily dosing for maintenance of remission of ulcerative colitis. Gastroenterology 2010. PMID: 20064514


  121. Mahadevan U. Pregnancy and inflammatory bowel disease. The Medical clinics of North America 2010. PMID: 19944798


  122. Mahadevan U, Kane S. Use of infliximab in pregnancy. The American journal of gastroenterology 2010. PMID: 20054309


  123. Mahadevan U. Pregnancy and inflammatory bowel disease. Gastroenterology clinics of North America 2009. PMID: 19913206


  124. Sewell JL, Mahadevan U. Of blemishes and bowels: isotretinoin and inflammatory bowel disease. Gastroenterology 2009. PMID: 19932213


  125. Mahadevan U. Cervical neoplasia risk in IBD: truth or hysteria? Inflammatory bowel diseases 2009. PMID: 19408322


  126. Moscandrew M, Mahadevan U, Kane S. General health maintenance in IBD. Inflammatory bowel diseases 2009. PMID: 19591135


  127. McCabe JM, Mahadevan U, Vidyarthi A. An obscure harbinger. Difficult diagnosis of Crohn's Disease. The American journal of medicine 2009. PMID: 19486711


  128. Sewell JL, Mahadevan U. A new answer to an old question: azathioprine withdrawal in quiescent Crohn's disease. Gastroenterology 2009. PMID: 19482103


  129. Hou JK, Mahadevan U. A 24-year-old pregnant woman with inflammatory bowel disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2009. PMID: 19410016


  130. Costouros NG, Niho H, Mahadevan U, Kerlan RK, Bloom AI. Angiographic embolization for control of life-threatening hemorrhage from benign rectal ulcers. Journal of vascular and interventional radiology : JVIR 2009. PMID: 19246210


  131. Thia KT, Mahadevan U, Feagan BG, Wong C, Cockeram A, Bitton A, Bernstein CN, Sandborn WJ. Ciprofloxacin or metronidazole for the treatment of perianal fistulas in patients with Crohn's disease: a randomized, double-blind, placebo-controlled pilot study. Inflammatory bowel diseases 2009. PMID: 18668682


  132. Sewell JL, Mahadevan U. Infliximab and surgical complications: truth or perception? Gastroenterology 2008. PMID: 19059260


  133. Dubinsky M, Abraham B, Mahadevan U. Management of the pregnant IBD patient. Inflammatory bowel diseases 2008. PMID: 18626967


  134. Mahadevan U. Continuing immunomodulators and biologic medications in pregnant IBD patients - pro. Inflammatory bowel diseases 2007. PMID: 17763475


  135. Plevy S, Salzberg B, Van Assche G, Regueiro M, Hommes D, Sandborn W, Hanauer S, Targan S, Mayer L, Mahadevan U, Frankel M, Lowder J. A phase I study of visilizumab, a humanized anti-CD3 monoclonal antibody, in severe steroid-refractory ulcerative colitis. Gastroenterology 2007. PMID: 17920064


  136. Mahadevan U, Sandborn WJ, Li DK, Hakimian S, Kane S, Corley DA. Pregnancy outcomes in women with inflammatory bowel disease: a large community-based study from Northern California. Gastroenterology 2007. PMID: 17764676


  137. Velayos F, Mahadevan U. Management of steroid-dependent ulcerative colitis: immunomodulatory agents, biologics, or surgery? Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2007. PMID: 17544992


  138. Mahadevan U. Gastrointestinal medications in pregnancy. Best practice & research. Clinical gastroenterology 2007. PMID: 17889812


  139. Mahadevan U. TNF-alpha antagonists: benefits beyond remission. Reviews in gastroenterological disorders 2007. PMID: 17392633


  140. Mahadevan U. Fertility and pregnancy in the patient with inflammatory bowel disease. Gut 2006. PMID: 16849349


  141. Mahadevan U, Kane S. American gastroenterological association institute medical position statement on the use of gastrointestinal medications in pregnancy. Gastroenterology 2006. PMID: 16831610


  142. Mahadevan U, Kane S. American gastroenterological association institute technical review on the use of gastrointestinal medications in pregnancy. Gastroenterology 2006. PMID: 16831611


  143. Mahadevan U. Pregnancy, Fertility, and Therapies for IBD. Gastroenterology & hepatology 2006. PMID: 28286451


  144. Mahadevan U. Mucosal healing in Crohn's disease: what you see is what you get? Gastrointestinal endoscopy 2006. PMID: 16500393


  145. Vesga L, Terdiman JP, Mahadevan U. Adalimumab use in pregnancy. Gut 2005. PMID: 15888806


  146. Mahadevan U, Terdiman JP, Aron J, Jacobsohn S, Turek P. Infliximab and semen quality in men with inflammatory bowel disease. Inflammatory bowel diseases 2005. PMID: 15803031


  147. Mahadevan U, Kane S, Sandborn WJ, Cohen RD, Hanson K, Terdiman JP, Binion DG. Intentional infliximab use during pregnancy for induction or maintenance of remission in Crohn's disease. Alimentary pharmacology & therapeutics 2005. PMID: 15771759


  148. Gill KR, Mahadevan U. Infliximab for the treatment of metastatic hepatic and pulmonary Crohn's disease. Inflammatory bowel diseases 2005. PMID: 15677920


  149. Mahadevan U. Medical treatment of ulcerative colitis. Clinics in colon and rectal surgery 2004. PMID: 20011280


  150. Mahadevan U, Marion JF, Present DH. Fistula response to methotrexate in Crohn's disease: a case series. Alimentary pharmacology & therapeutics 2003. PMID: 14616166


  151. Mahadevan U. 6TG: when less is more than you bargained for. Inflammatory bowel diseases 2003. PMID: 14677541


  152. Mathy C, Schneider K, Chen YY, Varma M, Terdiman JP, Mahadevan U. Gross versus microscopic pancolitis and the occurrence of neoplasia in ulcerative colitis. Inflammatory bowel diseases 2003. PMID: 14671483


  153. Mahadevan U, Sandborn WJ. Diagnosis and management of pouchitis. Gastroenterology 2003. PMID: 12761722


  154. Mahadevan U, Loftus EV, Tremaine WJ, Pemberton JH, Harmsen WS, Schleck CD, Zinsmeister AR, Sandborn WJ. Azathioprine or 6-mercaptopurine before colectomy for ulcerative colitis is not associated with increased postoperative complications. Inflammatory bowel diseases 2002. PMID: 12479645


  155. Mahadevan U, Loftus EV, Tremaine WJ, Sandborn WJ. Safety of selective cyclooxygenase-2 inhibitors in inflammatory bowel disease. The American journal of gastroenterology 2002. PMID: 12008668


  156. Mahadevan U, Sandborn WJ. Evolving medical therapies for Crohn's disease. Current gastroenterology reports 2001. PMID: 11696284


  157. Mahadevan U, Sandborn WJ. Infliximab for the treatment of orofacial Crohn's disease. Inflammatory bowel diseases 2001. PMID: 11233659


  158. Mahadevan U, Tremaine WJ, Johnson T, Pike MG, Mays DC, Lipsky JJ, Sandborn WJ. Intravenous azathioprine in severe ulcerative colitis: a pilot study. The American journal of gastroenterology 2000. PMID: 11151878