Samuel Brusca, MD, BS

Assistant Professor

Clinical interests: Critical care cardiologist with additional expertise in pulmonary hypertension. Focused on the management of patients with cardiogenic shock and cardiac diseases complicated by multi-organ failure.

Research interests: Cardiac intensive care unit processes improvement and educational initiatives. Using peripheral biomarkers to phenotype and risk stratify patients with pulmonary hypertension and shock.

Education
2022 - Cardiology Fellowship, University of California, San Francisco
2020 - Critical Care Medicine Fellowship, National Institutes of Health Clinical Center
2017 - Internal Medicine Residency, Johns Hopkins Hospital
MD, 2014 - , New York University School of Medicine
BS, 2010 - Neuroscience, Washington and Lee University
Publications

  1. O'Brien CG, Brusca SB, Barnett CF, Berg DD, Baird-Zars VM, Park JG, Bohula EA, Morrow DA, CCCTN Investigators. Using Selection Criteria From the DanGer Shock Trial in a Contemporary Cohort With Cardiogenic Shock. Journal of the American College of Cardiology 2024. PMID: 39387763


  2. Alkhunaizi FA, Smith N, Brusca SB, Furfaro D. The Management of Cardiogenic Shock From Diagnosis to Devices: A Narrative Review. CHEST Critical Care 2024. PMID: 38993934


  3. Brusca SB, Albert MA. Balancing the scales of adversity: a socioecological approach to reducing the global burden of stroke and cardiovascular disease. The Lancet. Neurology 2023. PMID: 37827182


  4. Barnett CF, Brusca SB, Hanff TC, Blumer V, Kaliff A, Kanwar M. Management of Cardiogenic Shock Unrelated to Acute Myocardial Infarction. The Canadian journal of cardiology 2023. PMID: 36731605


  5. Brusca SB, Galiatsatos P, Warner S, Li X, Powell-Wiley TM, Kadri SS, Solomon MA. Outcomes of Patients With Primary Cardiac Diagnoses Admitted to Cardiac vs Noncardiac Intensive Care Units. JACC Advances 2022. PMID: 36466046


  6. Thomas A, van Diepen S, Beekman R, Sinha SS, Brusca SB, Alviar CL, Jentzer J, Bohula EA, Katz JN, Shahu A, Barnett C, Morrow DA, Gilmore EJ, Solomon MA, Miller PE. Oxygen Supplementation and Hyperoxia in Critically Ill Cardiac Patients: From Pathophysiology to Clinical Practice. JACC Advances 2022. PMID: 36238193


  7. Brusca SB, Elinoff JM, Zou Y, Jang MK, Kong H, Demirkale CY, Sun J, Seifuddin F, Pirooznia M, Valantine HA, Tanba C, Chaturvedi A, Graninger GM, Harper B, Chen LY, Cole J, Kanwar M, Benza RL, Preston IR, Agbor-Enoh S, Solomon MA. Plasma Cell-Free DNA Predicts Survival and Maps Specific Sources of Injury in Pulmonary Arterial Hypertension. Circulation 2022. PMID: 36004627


  8. Brusca SB, Caughron H, Njoroge JN, Cheng R, O'Brien CG, Barnett CF. The shock team: a multidisciplinary approach to early patient phenotyping and appropriate care escalation in cardiogenic shock. 2022. PMID: 35612936


  9. Martin RL, Grant MJ, Kimani S, Midha S, May J, Patell R, Collier E, Furfaro D, Bodine C, Reap L, Shah N, DeLaune J, Brusca S, Olazagasti C, Goyal S, Rubinstein S, Hakim N, Qin S, Browning SL, Sena L, Gilbert J, Davidson M, Lovly CM, Seetharamu N, Rangachari D, Murphy M, Chatwal M, Paschal R, Henry E, Collichio F, Green JR. Forming the Hematology-Oncology Collaborative Videoconferencing (CO-VID) Learning Initiative: Experiential Lessons Learned From a Novel Trainee-Led Multidisciplinary Virtual Learning Platform. Volume 18 of Issue 1. JCO oncology practice 2021. PMID: 34242082


  10. Lu M, Blaine KP, Cullinane A, Hall C, Dulau-Florea A, Sun J, Chenwi HF, Graninger GM, Harper B, Thompson K, Krack J, Barnett CF, Brusca SB, Elinoff JM, Solomon MA. Pulmonary arterial hypertension patients display normal kinetics of clot formation using thrombelastography. Volume 11 of Issue 3. Pulmonary circulation 2021. PMID: 34249330


  11. Jentzer JC, Bihorac A, Brusca SB, Del Rio-Pertuz G, Kashani K, Kazory A, Kellum JA, Mao M, Moriyama B, Morrow DA, Patel HN, Rali AS, van Diepen S, Solomon MA, Critical Care Cardiology Working Group of the Heart Failure and Transplant Section Leadership Counci. Contemporary Management of Severe Acute Kidney Injury and Refractory Cardiorenal Syndrome: JACC Council Perspectives. Volume 76 of Issue 9. Journal of the American College of Cardiology 2020. PMID: 32854844


  12. Brusca SB, Zou Y, Elinoff JM. How low should we go? Potential benefits and ramifications of the pulmonary hypertension hemodynamic definitions proposed by the 6th World Symposium. Volume 26 of Issue 5. Current opinion in pulmonary medicine 2020. PMID: 32701671


  13. Katz JN, Sinha SS, Alviar CL, Dudzinski DM, Gage A, Brusca SB, Flanagan MC, Welch T, Geller BJ, Miller PE, Leonardi S, Bohula EA, Price S, Chaudhry SP, Metkus TS, O'Brien CG, Sionis A, Barnett CF, Jentzer JC, Solomon MA, Morrow DA, van Diepen S. COVID-19 and Disruptive Modifications to Cardiac Critical Care Delivery: JACC Review Topic of the Week. Volume 76 of Issue 1. Journal of the American College of Cardiology 2020. PMID: 32305402


  14. Brusca SB, Barnett C, Barnhart BJ, Weng W, Morrow DA, Soble JS, Katz JN, Wiley BM, van Diepen S, Gomez AD, Solomon MA. Role of Critical Care Medicine Training in the Cardiovascular Intensive Care Unit: Survey Responses From Dual Certified Critical Care Cardiologists. Journal of the American Heart Association 2019. PMID: 30879373


  15. Brusca S, Agbor-Enoh S. Environment, Epigenetics, and Differential Responses to Beryllium Exposure: Are We There Yet? Volume 60 of Issue 1. American journal of respiratory cell and molecular biology 2019. PMID: 30321053


  16. Hsu S, Brusca SB, Rhodes PS, Kolb TM, Mathai SC, Tedford RJ. Use of thermodilution cardiac output overestimates diagnoses of exercise-induced pulmonary hypertension. Volume 7 of Issue 1. Pulmonary circulation 2017. PMID: 28680584


  17. Scher JU, Ubeda C, Artacho A, Attur M, Isaac S, Reddy SM, Marmon S, Neimann A, Brusca S, Patel T, Manasson J, Pamer EG, Littman DR, Abramson SB. Decreased bacterial diversity characterizes the altered gut microbiota in patients with psoriatic arthritis, resembling dysbiosis in inflammatory bowel disease. Volume 67 of Issue 1. Arthritis & rheumatology (Hoboken, N.J.) 2015. PMID: 25319745


  18. Brusca SB, Abramson SB, Scher JU. Microbiome and mucosal inflammation as extra-articular triggers for rheumatoid arthritis and autoimmunity. Volume 26 of Issue 1. Current opinion in rheumatology 2014. PMID: 24247114