Robert Nissenson, PhD

Professor in Residence

Education
06/1980 - Postdoctoral Research in Endocrinology, University of California, San Francisco
06/1977 - Postdoctoral Research in Endocrinology, Mayo Clinic
Ph.D., 06/1976 - Physiology, Northwestern University Medical School
B.A., 06/1971 - Biology, Northwestern University
06/1969 - Chemistry, Cornell University
Publications

  1. Kim TY, Schwartz AV, Li X, Xu K, Kazakia GJ, Grunfeld C, Nissenson RA, Shoback DM, Schafer AL. Bone marrow adipose tissue composition and glycemic improvements after gastric bypass surgery. Bone reports 2022. PMID: 35734226


  2. Wang L, Roth T, Nakamura MC, Nissenson RA. Female-Specific Role of Progranulin to Suppress Bone Formation. Endocrinology 2019. PMID: 31237618


  3. Herber CB, Krause WC, Wang L, Bayrer JR, Li A, Schmitz M, Fields A, Ford B, Zhang Z, Reid MS, Nomura DK, Nissenson RA, Correa SM, Ingraham HA. Estrogen signaling in arcuate Kiss1 neurons suppresses a sex-dependent female circuit promoting dense strong bones. Nature communications 2019. PMID: 30635563


  4. Ho L, Wang L, Roth TM, Pan Y, Verdin EM, Hsiao EC, Nissenson RA. Sirtuin-3 Promotes Adipogenesis, Osteoclastogenesis, and Bone Loss in Aging Male Mice. Endocrinology 2017. PMID: 28911171


  5. Millard SM, Wang L, Wattanachanya L, O'Carroll D, Fields AJ, Pang J, Kazakia G, Lotz JC, Nissenson RA. Role of Osteoblast Gi Signaling in Age-Related Bone Loss in Female Mice. Endocrinology 2017. PMID: 28407060


  6. Wang L, Roth T, Abbott M, Ho L, Wattanachanya L, Nissenson RA. Osteoblast-derived FGF9 regulates skeletal homeostasis. Bone 2017. PMID: 28189801


  7. Hsiao EC, Millard SM, Nissenson RA. Gs/Gi Regulation of Bone Cell Differentiation: Review and Insights from Engineered Receptors. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 2016. PMID: 27643449


  8. Liu X, Ning AY, Chang NC, Kim H, Nissenson R, Wang L, Feeley BT. Investigating the cellular origin of rotator cuff muscle fatty infiltration and fibrosis after injury. Muscles, ligaments and tendons journal 2016. PMID: 27331027


  9. Shahnazari M, Turner RT, Iwaniec UT, Wronski TJ, Li M, Ferruzzi MG, Nissenson RA, Halloran BP. Dietary dried plum increases bone mass, suppresses proinflammatory cytokines and promotes attainment of peak bone mass in male mice. The Journal of nutritional biochemistry 2016. PMID: 27239754


  10. Abbott MJ, Roth TM, Ho L, Wang L, O'Carroll D, Nissenson RA. Negative Skeletal Effects of Locally Produced Adiponectin. PloS one 2015. PMID: 26230337


  11. Wang L, Carroll DO, Liu X, Roth T, Kim H, Halloran B, Nissenson RA. Effects of blockade of endogenous Gi signaling in Tie2-expressing cells on bone formation in a mouse model of heterotopic ossification. Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2015. PMID: 25773760


  12. Wang L, Hsiao EC, Lieu S, Scott M, O'Carroll D, Urrutia A, Conklin BR, Colnot C, Nissenson RA. Loss of Gi G-Protein-Coupled Receptor Signaling in Osteoblasts Accelerates Bone Fracture Healing. Volume 30 of Issue 10. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2015. PMID: 25917236


  13. Wattanachanya L, Wang L, Millard SM, Lu WD, O'Carroll D, Hsiao EC, Conklin BR, Nissenson RA. Assessing the osteoblast transcriptome in a model of enhanced bone formation due to constitutive Gs-G protein signaling in osteoblasts. Volume 333 of Issue 2. Experimental cell research 2015. PMID: 25704759


  14. Kang H, Dang AB, Joshi SK, Halloran B, Nissenson R, Zhang X, Li J, Kim HT, Liu X. Novel mouse model of spinal cord injury-induced heterotopic ossification. Journal of rehabilitation research and development 2014. PMID: 25436890


  15. Liu X, Kang H, Shahnazari M, Kim H, Wang L, Larm O, Adolfsson L, Nissenson R, Halloran B. A novel mouse model of trauma induced heterotopic ossification. Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2013. PMID: 24136593


  16. Shahnazari M, Chu V, Wronski TJ, Nissenson RA, Halloran BP. CXCL12/CXCR4 signaling in the osteoblast regulates the mesenchymal stem cell and osteoclast lineage populations. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013. PMID: 23704087


  17. Wattanachanya L, Lu WD, Kundu RK, Wang L, Abbott MJ, O'Carroll D, Quertermous T, Nissenson RA. Increased bone mass in mice lacking the adipokine apelin. Endocrinology 2013. PMID: 23584856


  18. Kao RS, Abbott MJ, Louie A, O'Carroll D, Lu W, Nissenson R. Constitutive protein kinase A activity in osteocytes and late osteoblasts produces an anabolic effect on bone. Bone 2013. PMID: 23583750


  19. Kao R, Lu W, Louie A, Nissenson R. Cyclic AMP signaling in bone marrow stromal cells has reciprocal effects on the ability of mesenchymal stem cells to differentiate into mature osteoblasts versus mature adipocytes. Endocrine 2012. PMID: 22695986


  20. Kazakia GJ, Speer D, Shanbhag S, Majumdar S, Conklin BR, Nissenson RA, Hsiao EC. Mineral composition is altered by osteoblast expression of an engineered G(s)-coupled receptor. Volume 89 of Issue 1. Calcified tissue international 2011. PMID: 21526395


  21. Mankani MH, Afghani S, Franco J, Launey M, Marshall S, Marshall GW, Nissenson R, Lee J, Tomsia AP, Saiz E. Lamellar spacing in cuboid hydroxyapatite scaffolds regulates bone formation by human bone marrow stromal cells. Tissue engineering. Part A 2011. PMID: 21294634


  22. Millard SM, Louie AM, Wattanachanya L, Wronski TJ, Conklin BR, Nissenson RA. Blockade of receptor-activated G(i) signaling in osteoblasts in vivo leads to site-specific increases in cortical and cancellous bone formation. Volume 26 of Issue 4. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011. PMID: 20939063


  23. Hsiao EC, Boudignon BM, Halloran BP, Nissenson RA, Conklin BR. Gs G protein-coupled receptor signaling in osteoblasts elicits age-dependent effects on bone formation. Volume 25 of Issue 3. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010. PMID: 20200944


  24. Hsiao EC, Millard SM, Louie A, Huang Y, Conklin BR, Nissenson RA. Ligand-mediated activation of an engineered gs g protein-coupled receptor in osteoblasts increases trabecular bone formation. Volume 24 of Issue 3. Molecular endocrinology (Baltimore, Md.) 2010. PMID: 20150184


  25. Conklin BR, Hsiao EC, Claeysen S, Dumuis A, Srinivasan S, Forsayeth JR, Guettier JM, Chang WC, Pei Y, McCarthy KD, Nissenson RA, Wess J, Bockaert J, Roth BL. Engineering GPCR signaling pathways with RASSLs. Volume 5 of Issue 8. Nature methods 2008. PMID: 18668035


  26. Hsiao EC, Boudignon BM, Chang WC, Bencsik M, Peng J, Nguyen TD, Manalac C, Halloran BP, Conklin BR, Nissenson RA. Osteoblast expression of an engineered Gs-coupled receptor dramatically increases bone mass. Volume 105 of Issue 4. Proceedings of the National Academy of Sciences of the United States of America 2008. PMID: 18212126


  27. Sode M, Burghardt AJ, Nissenson RA, Majumdar S. Resolution dependence of the non-metric trabecular structure indices. Bone 2007. PMID: 18276202


  28. Peng J, Bencsik M, Louie A, Lu W, Millard S, Nguyen P, Burghardt A, Majumdar S, Wronski TJ, Halloran B, Conklin BR, Nissenson RA. Conditional expression of a Gi-coupled receptor in osteoblasts results in trabecular osteopenia. Volume 149 of Issue 3. Endocrinology 2007. PMID: 18048501


  29. McCloskey DT, Turcato S, Wang GY, Turnbull L, Zhu BQ, Bambino T, Nguyen AP, Lovett DH, Nissenson RA, Karliner JS, Baker AJ. Expression of a Gi-coupled receptor in the heart causes impaired Ca2+ handling, myofilament injury, and dilated cardiomyopathy. Volume 294 of Issue 1. American journal of physiology. Heart and circulatory physiology 2007. PMID: 17965283


  30. Huang JC, Sakata T, Pfleger LL, Bencsik M, Halloran BP, Bikle DD, Nissenson RA. PTH differentially regulates expression of RANKL and OPG. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003. PMID: 14969393


  31. Chauvin S, Bencsik M, Bambino T, Nissenson RA. Parathyroid hormone receptor recycling: role of receptor dephosphorylation and beta-arrestin. Molecular endocrinology (Baltimore, Md.) 2002. PMID: 12456793


  32. Vilardaga JP, Krasel C, Chauvin S, Bambino T, Lohse MJ, Nissenson RA. Internalization determinants of the parathyroid hormone receptor differentially regulate beta-arrestin/receptor association. The Journal of biological chemistry 2001. PMID: 11726668


  33. Vilardaga JP, Lin I, Nissenson RA. Analysis of parathyroid hormone (PTH)/secretin receptor chimeras differentiates the role of functional domains in the pth/ pth-related peptide (PTHrP) receptor on hormone binding and receptor activation. Molecular endocrinology (Baltimore, Md.) 2001. PMID: 11435617


  34. Vilardaga JP, Frank M, Krasel C, Dees C, Nissenson RA, Lohse MJ. Differential conformational requirements for activation of G proteins and the regulatory proteins arrestin and G protein-coupled receptor kinase in the G protein-coupled receptor for parathyroid hormone (PTH)/PTH-related protein. The Journal of biological chemistry 2001. PMID: 11387315


  35. Gabarin N, Gavish H, Muhlrad A, Chen YC, Namdar-Attar M, Nissenson RA, Chorev M, Bab I. Mitogenic G(i) protein-MAP kinase signaling cascade in MC3T3-E1 osteogenic cells: activation by C-terminal pentapeptide of osteogenic growth peptide [OGP(10-14)] and attenuation of activation by cAMP. Journal of cellular biochemistry 2001. PMID: 11329614


  36. Nissenson RA. Parathyroid hormone-related protein. Reviews in endocrine & metabolic disorders 2000. PMID: 11706748


  37. Bliziotes M, Gunness M, Zhang X, Nissenson R, Wiren K. Reduced G-protein-coupled-receptor kinase 2 activity results in impairment of osteoblast function. Bone 2000. PMID: 10962347


  38. Turner PR, Mefford S, Christakos S, Nissenson RA. Apoptosis mediated by activation of the G protein-coupled receptor for parathyroid hormone (PTH)/PTH-related protein (PTHrP). Molecular endocrinology (Baltimore, Md.) 2000. PMID: 10674397


  39. Sheikh SP, Vilardarga JP, Baranski TJ, Lichtarge O, Iiri T, Meng EC, Nissenson RA, Bourne HR. Similar structures and shared switch mechanisms of the beta2-adrenoceptor and the parathyroid hormone receptor. Zn(II) bridges between helices III and VI block activation. The Journal of biological chemistry 1999. PMID: 10358054


  40. Huang Z, Bambino T, Chen Y, Lameh J, Nissenson RA. Role of signal transduction in internalization of the G protein-coupled receptor for parathyroid hormone (PTH) and PTH-related protein. Endocrinology 1999. PMID: 10067856


  41. Malecz N, Bambino T, Bencsik M, Nissenson RA. Identification of phosphorylation sites in the G protein-coupled receptor for parathyroid hormone. Receptor phosphorylation is not required for agonist-induced internalization. Molecular endocrinology (Baltimore, Md.) 1998. PMID: 9849959


  42. Nissenson RA. Parathyroid hormone (PTH)/PTHrP receptor mutations in human chondrodysplasia. Endocrinology 1998. PMID: 9832410


  43. Turner PR, Mefford S, Bambino T, Nissenson RA. Transmembrane residues together with the amino terminus limit the response of the parathyroid hormone (PTH) 2 receptor to PTH-related peptide. The Journal of biological chemistry 1998. PMID: 9461563


  44. Schipani E, Jensen GS, Pincus J, Nissenson RA, Gardella TJ, Jüppner H. Constitutive activation of the cyclic adenosine 3',5'-monophosphate signaling pathway by parathyroid hormone (PTH)/PTH-related peptide receptors mutated at the two loci for Jansen's metaphyseal chondrodysplasia. Molecular endocrinology (Baltimore, Md.) 1997. PMID: 9178745


  45. Huang Z, Chen Y, Pratt S, Chen TH, Bambino T, Nissenson RA, Shoback DM. The N-terminal region of the third intracellular loop of the parathyroid hormone (PTH)/PTH-related peptide receptor is critical for coupling to cAMP and inositol phosphate/Ca2+ signal transduction pathways. The Journal of biological chemistry 1996. PMID: 8969199


  46. Lee K, Lanske B, Karaplis AC, Deeds JD, Kohno H, Nissenson RA, Kronenberg HM, Segre GV. Parathyroid hormone-related peptide delays terminal differentiation of chondrocytes during endochondral bone development. Endocrinology 1996. PMID: 8895385


  47. Jobert AS, Fernandes I, Turner G, Coureau C, Prie D, Nissenson RA, Friedlander G, Silve C. Expression of alternatively spliced isoforms of the parathyroid hormone (PTH)/PTH-related peptide receptor messenger RNA in human kidney and bone cells. Molecular endocrinology (Baltimore, Md.) 1996. PMID: 8885241


  48. Lane NE, Kimmel DB, Nilsson MH, Cohen FE, Newton S, Nissenson RA, Strewler GJ. Bone-selective analogs of human PTH(1-34) increase bone formation in an ovariectomized rat model. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996. PMID: 9157776


  49. Blind E, Bambino T, Huang Z, Bliziotes M, Nissenson RA. Phosphorylation of the cytoplasmic tail of the PTH/PTHrP receptor. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996. PMID: 9157772


  50. Turner PR, Bambino T, Nissenson RA. A putative selectivity filter in the G-protein-coupled receptors for parathyroid hormone and secretion. The Journal of biological chemistry 1996. PMID: 8621578


  51. Turner PR, Bambino T, Nissenson RA. Mutations of neighboring polar residues on the second transmembrane helix disrupt signaling by the parathyroid hormone receptor. Molecular endocrinology (Baltimore, Md.) 1996. PMID: 8825553


  52. Blind E, Bambino T, Nissenson RA. Agonist-stimulated phosphorylation of the G protein-coupled receptor for parathyroid hormone (PTH) and PTH-related protein. Endocrinology 1995. PMID: 7664644


  53. Huang Z, Chen Y, Pratt S, Chen TH, Bambino T, Shoback DM, Nissenson RA. Mutational analysis of the cytoplasmic tail of the G protein-coupled receptor for parathyroid hormone (PTH) and PTH-related protein: effects on receptor expression and signaling. Molecular endocrinology (Baltimore, Md.) 1995. PMID: 7491116


  54. Funk JL, Lausier J, Moser AH, Shigenaga JK, Huling S, Nissenson RA, Strewler GJ, Grunfeld C, Feingold KR. Endotoxin induces parathyroid hormone-related protein gene expression in splenic stromal and smooth muscle cells, not in splenic lymphocytes. Endocrinology 1995. PMID: 7628377


  55. Huang Z, Chen Y, Nissenson RA. The cytoplasmic tail of the G-protein-coupled receptor for parathyroid hormone and parathyroid hormone-related protein contains positive and negative signals for endocytosis. The Journal of biological chemistry 1995. PMID: 7814366


  56. Schermer DT, Bradley MS, Bambino TH, Nissenson RA, Strewler GJ. Functional properties of a synthetic chicken parathyroid hormone-related protein 1-36 fragment. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1994. PMID: 7942150


  57. Babich M, Alford GE, Nissenson RA. A novel phospholipase C inhibitor and phorbol esters reveal selective regulation of thrombin- and parathyroid hormone-stimulated signaling pathways in rat osteosarcoma cells. The Journal of pharmacology and experimental therapeutics 1994. PMID: 8169821


  58. Strewler GJ, Budayr AA, Clark OH, Nissenson RA. Production of parathyroid hormone by a malignant nonparathyroid tumor in a hypercalcemic patient. The Journal of clinical endocrinology and metabolism 1993. PMID: 7684395


  59. Nissenson RA, Huang Z, Blind E, Shoback D. Structure and function of the receptor for parathyroid hormone and parathyroid hormone-related protein. Receptor 1993. PMID: 8167570


  60. Strewler GJ, Chan SD, Globus RK, Schermer DT, Nissenson RA. Actions of parathyroid hormone-related protein as an embryonic differentiation factor. Journal of endocrinological investigation 1992. PMID: 1300340


  61. Klein RF, Nissenson RA, Strewler GJ. Pertussis toxin inhibits hormonal stimulation of bone resorption in fetal rat limb bones. The Journal of pharmacology and experimental therapeutics 1991. PMID: 1653845


  62. Babich M, Choi H, Johnson RM, King KL, Alford GE, Nissenson RA. Thrombin and parathyroid hormone mobilize intracellular calcium in rat osteosarcoma cells by distinct pathways. Endocrinology 1991. PMID: 1874183


  63. Schermer DT, Chan SD, Bruce R, Nissenson RA, Wood WI, Strewler GJ. Chicken parathyroid hormone-related protein and its expression during embryologic development. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1991. PMID: 1709333


  64. Karpf DB, Bambino T, Alford G, Nissenson RA. Features of the renal parathyroid hormone-parathyroid hormone-related protein receptor derived from structural studies of receptor fragments. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1991. PMID: 1851372


  65. Cohen FE, Strewler GJ, Bradley MS, Carlquist M, Nilsson M, Ericsson M, Ciardelli TL, Nissenson RA. Analogues of parathyroid hormone modified at positions 3 and 6. Effects on receptor binding and activation of adenylyl cyclase in kidney and bone. The Journal of biological chemistry 1991. PMID: 1846369


  66. Pun KK, Ho PW, Nissenson RA, Arnaud CD. Desensitization of parathyroid hormone receptors on cultured bone cells. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1990. PMID: 1963732


  67. Strewler GJ, Nissenson RA. Hypercalcemia in malignancy. The Western journal of medicine 1990. PMID: 2293469


  68. Chan SD, Strewler GJ, Nissenson RA. Transcriptional activation of Gs alpha expression by retinoic acid and parathyroid hormone-related protein in F9 teratocarcinoma cells. The Journal of biological chemistry 1990. PMID: 2122968


  69. Chan SD, Strewler GJ, King KL, Nissenson RA. Expression of a parathyroid hormone-like protein and its receptor during differentiation of embryonal carcinoma cells. Molecular endocrinology (Baltimore, Md.) 1990. PMID: 2177844


  70. Babich M, King KL, Nissenson RA. Thrombin stimulates inositol phosphate production and intracellular free calcium by a pertussis toxin-insensitive mechanism in osteosarcoma cells. Endocrinology 1990. PMID: 2153536


  71. Strewler GJ, Nissenson RA. Peptide mediators of hypercalcemia in malignancy. Annual review of medicine 1990. PMID: 2184736


  72. Budayr AA, Nissenson RA, Klein RF, Pun KK, Clark OH, Diep D, Arnaud CD, Strewler GJ. Increased serum levels of a parathyroid hormone-like protein in malignancy-associated hypercalcemia. Annals of internal medicine 1989. PMID: 2817628


  73. Budayr AA, Halloran BP, King JC, Diep D, Nissenson RA, Strewler GJ. High levels of a parathyroid hormone-like protein in milk. Proceedings of the National Academy of Sciences of the United States of America 1989. PMID: 2550932


  74. Babich M, King KL, Nissenson RA. G protein-dependent activation of a phosphoinositide-specific phospholipase C in UMR-106 osteosarcoma cell membranes. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1989. PMID: 2554686


  75. Karpf DB, Arnaud CD, Bambino T, Duffy D, King KL, Winer J, Nissenson RA. Structural properties of the renal parathyroid hormone receptor: hydrodynamic analysis and protease sensitivity. Endocrinology 1988. PMID: 2848681


  76. Nissenson RA, Diep D, Strewler GJ. Synthetic peptides comprising the amino-terminal sequence of a parathyroid hormone-like protein from human malignancies. Binding to parathyroid hormone receptors and activation of adenylate cyclase in bone cells and kidney. The Journal of biological chemistry 1988. PMID: 2843501


  77. Pun KK, Arnaud CD, Nissenson RA. Parathyroid hormone receptors in human dermal fibroblasts: structural and functional characterization. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1988. PMID: 2851922


  78. Klein RF, Nissenson RA, Strewler GJ. Forskolin mimics the effects of calcitonin but not parathyroid hormone on bone resorption in vitro. Bone and mineral 1988. PMID: 2847839


  79. Thiede MA, Strewler GJ, Nissenson RA, Rosenblatt M, Rodan GA. Human renal carcinoma expresses two messages encoding a parathyroid hormone-like peptide: evidence for the alternative splicing of a single-copy gene. Proceedings of the National Academy of Sciences of the United States of America 1988. PMID: 3290897


  80. Strewler GJ, Stern PH, Jacobs JW, Eveloff J, Klein RF, Leung SC, Rosenblatt M, Nissenson RA. Parathyroid hormonelike protein from human renal carcinoma cells. Structural and functional homology with parathyroid hormone. The Journal of clinical investigation 1987. PMID: 3680530


  81. Karpf DB, Arnaud CD, King K, Bambino T, Winer J, Nyiredy K, Nissenson RA. The canine renal parathyroid hormone receptor is a glycoprotein: characterization and partial purification. Biochemistry 1987. PMID: 2827760


  82. Forero MS, Klein RF, Nissenson RA, Nelson K, Heath H, Arnaud CD, Riggs BL. Effect of age on circulating immunoreactive and bioactive parathyroid hormone levels in women. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1987. PMID: 3455620


  83. Nissenson RA, Karpf D, Bambino T, Winer J, Canga M, Nyiredy K, Arnaud CD. Covalent labeling of a high-affinity, guanyl nucleotide sensitive parathyroid hormone receptor in canine renal cortex. Biochemistry 1987. PMID: 3036211


  84. Klein RF, Strewler GJ, Leung SC, Nissenson RA. Parathyroid hormone-like adenylate cyclase-stimulating activity from a human carcinoma is associated with bone-resorbing activity. Endocrinology 1987. PMID: 3026777


  85. Strewler GJ, Nissenson RA. Nonparathyroid hypercalcemia. Advances in internal medicine 1987. PMID: 3030065


  86. Teitelbaum AP, Nissenson RA, Zitzner LA, Simon K. Dual regulation of PTH-stimulated adenylate cyclase activity by GTP. The American journal of physiology 1986. PMID: 3777181


  87. Strewler GJ, Wronski TJ, Halloran BP, Miller SC, Leung SC, Williams RD, Nissenson RA. Pathogenesis of hypercalcemia in nude mice bearing a human renal carcinoma. Endocrinology 1986. PMID: 3013591


  88. Nissenson RA, Mann E, Winer J, Teitelbaum AP, Arnaud CD. Solubilization of a guanine nucleotide-sensitive parathyroid hormone-receptor complex from canine renal cortex. Endocrinology 1986. PMID: 3004900


  89. Nissenson RA, Mann E, Winer J, Teitelbaum A, Arnaud CD. Solubilization of a guanine nucleotide-sensitive parathyroid hormone-receptor complex from canine renal cortex. Advances in experimental medicine and biology 1986. PMID: 3031942


  90. Calvo MS, Fryer MJ, Laakso KJ, Nissenson RA, Price PA, Murray TM, Heath H. Structural requirements for parathyroid hormone action in mature bone. Effects on release of cyclic adenosine monophosphate and bone gamma-carboxyglutamic acid-containing protein from perfused rat hindquarters. The Journal of clinical investigation 1985. PMID: 3001148


  91. Nissenson RA, Strewler GJ, Williams RD, Leung SC. Activation of the parathyroid hormone receptor-adenylate cyclase system in osteosarcoma cells by a human renal carcinoma factor. Cancer research 1985. PMID: 2996759


  92. Stern PH, Krieger NS, Nissenson RA, Williams RD, Winkler ME, Derynck R, Strewler GJ. Human transforming growth factor-alpha stimulates bone resorption in vitro. The Journal of clinical investigation 1985. PMID: 3877079


  93. Toffaletti J, Nissenson R, Endres D, McGarry E, Mogollon G. Influence of continuous infusion of citrate on responses of immunoreactive parathyroid hormone, calcium and magnesium components, and other electrolytes in normal adults during plateletapheresis. The Journal of clinical endocrinology and metabolism 1985. PMID: 3980672


  94. Nissenson RA, Teitelbaum AP, Arnaud CD. Assay for parathyroid hormone receptors. Methods in enzymology 1985. PMID: 2985929


  95. Teitelbaum AP, Nissenson RA, Arnaud CD. Assays for calcitonin receptors. Methods in enzymology 1985. PMID: 2985927


  96. Clark OH, Gerend PL, Nissenson RA. Mechanisms for increased adenylate cyclase responsiveness to TSH in neoplastic human thyroid tissue. World journal of surgery 1984. PMID: 6091347


  97. Hsu FS, Clark OH, Serata TY, Nissenson RA. Rapid localization of parathyroid tumors by selective venous catheterization and parathyroid hormone bioassay. Surgery 1983. PMID: 6648799


  98. Zanelli JM, Kent JC, Rafferty B, Nissenson RA, Nice EC, Capp MW, O'Hare MJ. High-performance liquid chromatographic methods for the analysis of human parathyroid hormone in reference standards, parathyroid tissue and biological fluids. Journal of chromatography 1983. PMID: 6672025


  99. Mahoney CA, Nissenson RA. Canine renal receptors for parathyroid hormone. Down-regulation in vivo by exogenous parathyroid hormone. The Journal of clinical investigation 1983. PMID: 6308053


  100. Clark OH, Gerend PL, Goretzki P, Nissenson RA. Characterization of the thyrotropin receptor-adenylate cyclase system in neoplastic human thyroid tissue. The Journal of clinical endocrinology and metabolism 1983. PMID: 6304132


  101. Fox J, Scott M, Nissenson RA, Heath H. Effect of plasma calcium concentration on the metabolic clearance rate of parathyroid hormone in the dog. The Journal of laboratory and clinical medicine 1983. PMID: 6854136


  102. Law WM, Nissenson RA, Klee GG, Heath H. Preparation of synthetic bovine parathyroid hormone fragment 1-34 for parenteral use in human studies. The Journal of clinical endocrinology and metabolism 1983. PMID: 6841565


  103. Yanagawa N, Nissenson RA, Edwards B, Yeung P, Trizna W, Fine LG. Functional profile of the isolated uremic nephron: intrinsic adaptation of phosphate transport in the rabbit proximal tubule. Kidney international 1983. PMID: 6876563


  104. Strewler GJ, Williams RD, Nissenson RA. Human renal carcinoma cells produce hypercalcemia in the nude mouse and a novel protein recognized by parathyroid hormone receptors. The Journal of clinical investigation 1983. PMID: 6298282


  105. Teitelbaum AP, Nissenson RA, Arnaud CD. Coupling of the canine renal parathyroid hormone receptor to adenylate cyclase: modulation by guanyl nucleotides and N-ethylmaleimide. Endocrinology 1982. PMID: 6290186


  106. Nissenson RA. Functional properties of parathyroid hormone receptors. Mineral and electrolyte metabolism 1982. PMID: 6300627


  107. Clark OH, Gerend PL, Nissenson RA. Thyrotropin binding and adenylate cyclase activation in normal and neoplastic human thyroid tissue: lack of effect of thyroglobulin. The Journal of clinical endocrinology and metabolism 1982. PMID: 7076796


  108. Draper MW, Nissenson RA, Winer J, Ramachandran J, Arnaud CD. Photoaffinity labeling of the canine renal receptor for parathyroid hormone. The Journal of biological chemistry 1982. PMID: 6277947


  109. Nissenson RA, Abbott SR, Pua K, Zitzner L, Teitelbaum AP, Clark OH. Assessment of biologically active parathyroid hormone in hyperparathyroid man. Advances in experimental medicine and biology 1982. PMID: 7180664


  110. Teitelbaum AP, Pliam NB, Silve C, Abbott SR, Nissenson RA, Arnaud CD. Functional properties of parathyroid hormone receptors in kidney and bone. Advances in experimental medicine and biology 1982. PMID: 6295095


  111. Clark OH, Gerend PL, Cote TC, Nissenson RA. Thyrotropin binding and adenylate cyclase stimulation in thyroid neoplasms. Surgery 1981. PMID: 6266060


  112. Nissenson RA, Abbott SR, Teitelbaum AP, Clark OH, Arnaud CD. Endogenous biologically active human parathyroid hormone: measurement by a guanyl nucleotide-amplified renal adenylate cyclase assay. The Journal of clinical endocrinology and metabolism 1981. PMID: 7228991


  113. Nissenson RA, Nyiredy KO, Arnaud CD. Guanyl nucleotide potentiation of parathyroid hormone-stimulated adenylate cyclase in chicken renal plasma membranes: a receptor-independent effect. Endocrinology 1981. PMID: 6260469


  114. Nissenson RA, Flouret G, Hechter O. Oxytocin receptors coupled to uterine contraction in estrogen-dominated rabbits. Biochimica et biophysica acta 1980. PMID: 6244002


  115. Abbott SR, Nissenson RA, Teitelbaum AP, Clark OH, Arnaud CD. Biologically active parathyroid hormone in human hyperparathyroid serum: assay and characterization. Transactions of the Association of American Physicians 1980. PMID: 7245574


  116. Nissenson RA, Kugai N, Arnaud CD. The parathyroid hormone receptor-adenylate cyclase system in chicken kidney. Advances in experimental medicine and biology 1980. PMID: 6252762


  117. Nissenson RA, Kugai N, Arnaud CD. The renal parathyroid hormone receptor-adenylate cyclase system in vitro and in vivo. Progress in biochemical pharmacology 1980. PMID: 6259654


  118. Nissenson RA, Arnaud CD. Properties of the parathyroid hormone receptor-adenylate cyclase system in chicken renal plasma membranes. The Journal of biological chemistry 1979. PMID: 216694


  119. Nissenson R, Fluoret G, Hechter O. Opposing effects of estradiol and progesterone on oxytocin receptors in rabbit uterus. Proceedings of the National Academy of Sciences of the United States of America 1978. PMID: 205880


  120. Kugai N, Dorantes L, Nissenson R, Arnaud CD. Parathyroid hormone receptors and stimulation of renal cyclic 3', 5' AMP in vitro: physiological relevance? Advances in experimental medicine and biology 1978. PMID: 213954