Midori Kato-Maeda, MD, MA

Professor

Research Interests

Dr. Kato-Maeda’s research activities focuses on 1) transmission of Mycobacterium tuberculosis (MTB), 2) drug- resistant tuberculosis, and 3) tuberculosis diagnosis.

Dr. Kato-Maeda, along with her U.S. and international collaborators, established community-based studies in San Francisco, Tanzania, and Uganda to study the transmission dynamics of MTB, using molecular epidemiology tools to identify patient and environmental factors that can be modified to decrease transmission of MTB, and to identify populations that have a high risk of infection. These studies have resulted in guided tuberculosis control interventions.

Another goal of her research is to determine the impact of bacterial characteristics on the transmission dynamics of MTB. Dr. Kato-Maeda and her collaborators developed the method to classify MTB in phylogenetic sound groups. This classification revolutionized the study of the impact of bacterial factors on the clinical and epidemiological phenotypes of this disease. They identified lineages of MTB that cause more secondary cases of tuberculosis, suggesting that bacterial factors contribute to the pathogenicity of MTB. Importantly, based on these studies, they created and published a collection of well-characterized clinical MTB strains representing different lineages which will be used by the global TB research community for in vitro and in animal studies. These research projects have resulted in a biobank with more than 3,000 clinical isolates of MTB and MTB DNA and the associated metadata, which they have used for new projects with collaborators inside and outside of UCSF.

Dr. Kato-Maeda’s studies in drug-resistant tuberculosis are focused on identifying novel genomic factors that govern drug-resistant tuberculosis and the impact of the introduction of novel drugs on the epidemiology of drug-resistant tuberculosis. These studies are being performed in collaboration with a strong team of multidisciplinary researchers from the Philippines and Japan. As a result of this project, they have created a research-specific biobank with more than 900 isolates of drug resistant MTB.

Dr. Kato-Maeda is a member of the Rapid Research for Diagnostics Development in TB Network (R2D2 TB Network), an initiative led by Drs. Adithya Cattamanchi and Payam Nahid at UCSF. The network involves clinical sites in the Philippines, Vietnam, Uganda, South Africa, and India. Dr. Kato-Maeda leads the specimen acquisition, processing, storage, shipping, and distribution as well as the quality assurance and quality control activities to ensure procedures are followed and performed to standard to ensure good quality specimens and contribute to the discussions with the developers about their assays.

Dr. Kato-Maeda’s unique expertise in mycobacteriology and MTB genomics has also enabled her to be an integral part of projects led by other members of the UCSF Center for Tuberculosis (https://tb.ucsf.edu/), and her laboratory serves as their core lab.

Dr. Kato-Maeda’s research projects have always been conducive to training, transfer of technology, and capacity building for our international collaborators.

Education
2022 - Diversity, Equity, and Inclusion Champion Training, University of California
Masters, 1998 - Medical Sciences, Instituto Nacional de la Nutricion, Mexico
Infectious Diseases, 1996 - Infectious Diseases, Instituto Nacional de la Nutricion, Mexico
Internal Medicine, 1994 - Internal Medicine, Instituto Nacional de la Nutricion, Mexico
M.D., 1990 - Medicine, Escuela Mexicana de Medicina, Universidad La Salle, Mexico City
Publications

  1. Crowder R, Kato-Maeda M, Schwem B, Dela Tonga A, Geocaniga-Gaviola DM, Lopez E, Valdez CL, Lim AR, Hunat N, Sedusta AG, Sacopon CA, Atienza GAM, Bulag E, Lim D, Bascuña J, Shah K, Basillio RP, Berger CA, Lopez MCDP, Sen S, Allender C, Folkerts M, Karaoz U, Brodie E, Mitarai S, Garfin AMC, Ama MC, Engelthaler DM, Cattamanchi A, Destura R. Impact of heteroresistance on treatment outcomes of people with drug-resistant TB. IJTLD open 2024. PMID: 39398438


  2. Kendall EA, Kitonsa PJ, Nalutaaya A, Robsky KO, Erisa KC, Mukiibi J, Cattamanchi A, Kato-Maeda M, Katamba A, Dowdy D. Decline in prevalence of tuberculosis following an intensive case finding campaign and the COVID-19 pandemic in an urban Ugandan community. Thorax 2023. PMID: 38050134


  3. Zwyer M, Rutaihwa LK, Windels E, Hella J, Menardo F, Sasamalo M, Sommer G, Schm?lling L, Borrell S, Reinhard M, D?tsch A, Hiza H, Stritt C, Sikalengo G, Fenner L, De Jong BC, Kato-Maeda M, Jugheli L, Ernst JD, Niemann S, Jeljeli L, Ballif M, Egger M, Rakotosamimanana N, Yeboah-Manu D, Asare P, Malla B, Dou HY, Zetola N, Wilkinson RJ, Cox H, Carter EJ, Gnokoro J, Yotebieng M, Gotuzzo E, Abimiku A, Avihingsanon A, Xu ZM, Fellay J, Portevin D, Reither K, Stadler T, Gagneux S, Brites D. Back-to-Africa introductions of Mycobacterium tuberculosis as the main cause of tuberculosis in Dar es Salaam, Tanzania. PLoS pathogens 2023. PMID: 37014917


  4. Huddart S, Geocaniga-Gaviola DM, Crowder R, Lim AR, Lopez E, Valdez CL, Berger CA, Destura R, Kato-Maeda M, Cattamanchi A, Garfin AMC. Adherence trajectory as an on-treatment risk indicator among drug-resistant TB patients in the Philippines. PloS one 2022. PMID: 36346814


  5. Jaganath D, Reza TF, Wambi P, Nakafeero J, Kiconco E, Nanyonga G, Oumo EA, Nsereko MC, Sekadde MP, Nabukenya-Mudiope MG, Kato-Maeda M, Andama A, Yoon C, Mohanty S, Wobudeya E, Cattamanchi A. The Role of C-Reactive Protein as a Triage Tool for Pulmonary Tuberculosis in Children. 2022. PMID: 35451001


  6. Andama A, Whitman GR, Crowder R, Reza TF, Jaganath D, Mulondo J, Nalugwa TK, Semitala FC, Worodria W, Cook C, Wood RC, Weigel KM, Olson AM, Lohmiller Shaw J, Kato-Maeda M, Denkinger CM, Nahid P, Cangelosi GA, Cattamanchi A. Accuracy of Tongue Swab Testing Using Xpert MTB-RIF Ultra for Tuberculosis Diagnosis. Journal of clinical microbiology 2022. PMID: 35758702


  7. Ordaz-Vázquez A, Torres-González P, Cruz-Hervert P, Ferreyra-Reyes L, Delgado-Sánchez G, García-García L, Kato-Maeda M, Ponce-De-León A, Sifuentes-Osornio J, Bobadilla-Del-Valle M. Genetic diversity and primary drug resistance transmission in Mycobacterium tuberculosis in southern Mexico. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2021. PMID: 34245908


  8. Kendall EA, Kitonsa PJ, Nalutaaya A, Erisa KC, Mukiibi J, Nakasolya O, Isooba D, Baik Y, Robsky KO, Kato-Maeda M, Cattamanchi A, Katamba A, Dowdy DW. The Spectrum of Tuberculosis Disease in an Urban Ugandan Community and Its Health Facilities. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2021. PMID: 33283227


  9. Jaganath D, Wambi P, Reza TF, Nakafeero J, Aben EO, Kiconco E, Nannyonga G, Nsereko M, Sekadde MP, Mudiope M, Kato-Maeda M, Starke J, Andama A, Mohanty S, Wobudeya E, Cattamanchi A. A Prospective Evaluation of Xpert MTB/RIF Ultra for Childhood Pulmonary Tuberculosis in Uganda. Journal of the Pediatric Infectious Diseases Society 2021. PMID: 33416072


  10. Fabrizio Menardo, Liliana K. Rutaihwa, Michaela Zwyer, Sonia Borrell, Iñaki Comas, Emilyn Costa Conceição, Mireia Coscolla, Helen Cox, Moses Joloba, Horng-Yunn Dou, Julia Feldmann, Lukas Fenner, Janet Fyfe, Qian Gao, Darío García de Viedma, Alberto L. Garcia-Basteiro, Sebastian M. Gygli, Jerry Hella, Hellen Hiza, Levan Jugheli, Lujeko Kamwela, Midori Kato-Maeda, Qingyun Liu, Serej D. Ley, Chloe Loiseau, Surakameth Mahasirimongkol, Bijaya Malla, Prasit Palittapongarnpim, Niaina Rakotosamimanana, Voahangy Rasolofo, Miriam Reinhard, Klaus Reither, Mohamed Sasamalo, Rafael Silva Duarte, Christophe Sola, Philip Suffys, Karla Valeria Batista Lima, Dorothy Yeboah-Manu, Christian Beisel, Daniela Brites, Sebastien Gagneux. Local adaptation in populations of Mycobacterium tuberculosis endemic to the Indian Ocean Rim. F1000Research 2021. PMID:


  11. Menardo F, Rutaihwa LK, Zwyer M, Borrell S, Comas I, Conceição EC, Coscolla M, Cox H, Joloba M, Dou HY, Feldmann J, Fenner L, Fyfe J, Gao Q, García de Viedma D, Garcia-Basteiro AL, Gygli SM, Hella J, Hiza H, Jugheli L, Kamwela L, Kato-Maeda M, Liu Q, Ley SD, Loiseau C, Mahasirimongkol S, Malla B, Palittapongarnpim P, Rakotosamimanana N, Rasolofo V, Reinhard M, Reither K, Sasamalo M, Silva Duarte R, Sola C, Suffys P, Batista Lima KV, Yeboah-Manu D, Beisel C, Brites D, Gagneux S. Local adaptation in populations of Mycobacterium tuberculosis endemic to the Indian Ocean Rim. F1000Research 2021. PMID: 33732436


  12. Midori Kato-Maeda, Annie Luetkemeyer, Peter M. Small. Tuberculosis Associated with HIV Infection. 2021. PMID:


  13. Kendall EA, Kamoga C, Kitonsa PJ, Nalutaaya A, Salvatore PP, Robsky K, Nakasolya O, Mukiibi J, Isooba D, Cattamanchi A, Kato-Maeda M, Katamba A, Dowdy DW. Empiric treatment of pulmonary TB in the Xpert era: Correspondence of sputum culture, Xpert MTB/RIF, and clinical diagnoses. PloS one 2019. PMID: 31339935


  14. Kato-Maeda M, Choi JC, Jarlsberg LG, Grinsdale JA, Higashi J, Kawamura LM, Osmond DH, Hopewell PC. Magnitude of Mycobacterium tuberculosis transmission among household and non-household contacts of TB patients. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2019. PMID: 31064622


  15. Borrell S, Trauner A, Brites D, Rigouts L, Loiseau C, Coscolla M, Niemann S, De Jong B, Yeboah-Manu D, Kato-Maeda M, Feldmann J, Reinhard M, Beisel C, Gagneux S. Reference set of Mycobacterium tuberculosis clinical strains: A tool for research and product development. PloS one 2019. PMID: 30908506


  16. Robert Loddenkemper, John F. Murray, Christoph Gradmann, Philip C. Hopewell, Midori Kato-Maeda. History of tuberculosis. Tuberculosis 2018. PMID:


  17. Roa MB, Tablizo FA, Morado EKD, Cunanan LF, Uy IDC, Ng KCS, Manalastas-Cantos KG, Reyes JM, Ganchua SKC, Ang CF, Kato-Maeda M, Cattamanchi A, Karaoz U, Destura RV, Lluisma AO. Whole genome sequencing and single nucleotide polymorphisms in multi-drug resistant clinical isolates of Mycobacterium tuberculosis from the Philippines. Journal of global antimicrobial resistance 2018. PMID: 30130640


  18. Nahid P, Jarlsberg LG, Kato-Maeda M, Segal MR, Osmond DH, Gagneux S, Dobos K, Gold M, Hopewell PC, Lewinsohn DM. Interplay of strain and race/ethnicity in the innate immune response to M. tuberculosis. PloS one 2018. PMID: 29787561


  19. Chamie G, Kato-Maeda M, Emperador DM, Wandera B, Mugagga O, Crandall J, Janes M, Marquez C, Kamya MR, Charlebois ED, Havlir DV. Spatial overlap links seemingly unconnected genotype-matched TB cases in rural Uganda. Volume 13 of Issue 2. PloS one 2018. PMID: 29438413


  20. Feng JY, Jarlsberg LG, Salcedo K, Rose J, Janes M, Lin SG, Osmond DH, Jost KC, Soehnlen MK, Flood J, Graviss EA, Desmond E, Moonan PK, Nahid P, Hopewell PC, Kato-Maeda M. Clinical and bacteriological characteristics associated with clustering of multidrug-resistant tuberculosis. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2017. PMID: 28513421


  21. Feng JY, Jarlsberg LG, Rose J, Grinsdale JA, Janes M, Higashi J, Osmond DH, Nahid P, Hopewell PC, Kato-Maeda M. Impact of Euro-American sublineages of Mycobacterium tuberculosis on new infections among named contacts. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2017. PMID: 28399965


  22. Stucki D, Brites D, Jeljeli L, Coscolla M, Liu Q, Trauner A, Fenner L, Rutaihwa L, Borrell S, Luo T, Gao Q, Kato-Maeda M, Ballif M, Egger M, Macedo R, Mardassi H, Moreno M, Tudo Vilanova G, Fyfe J, Globan M, Thomas J, Jamieson F, Guthrie JL, Asante-Poku A, Yeboah-Manu D, Wampande E, Ssengooba W, Joloba M, Henry Boom W, Basu I, Bower J, Saraiva M, Vaconcellos SEG, Suffys P, Koch A, Wilkinson R, Gail-Bekker L, Malla B, Ley SD, Beck HP, de Jong BC, Toit K, Sanchez-Padilla E, Bonnet M, Gil-Brusola A, Frank M, Penlap Beng VN, Eisenach K, Alani I, Wangui Ndung'u P, Revathi G, Gehre F, Akter S, Ntoumi F, Stewart-Isherwood L, Ntinginya NE, Rachow A, Hoelscher M, Cirillo DM, Skenders G, Hoffner S, Bakonyte D, Stakenas P, Diel R, Crudu V, Moldovan O, Al-Hajoj S, Otero L, Barletta F, Jane Carter E, Diero L, Supply P, Comas I, Niemann S, Gagneux S. Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages. Nature genetics 2016. PMID: 27798628


  23. Walter ND, de Jong BC, Garcia BJ, Dolganov GM, Worodria W, Byanyima P, Musisi E, Huang L, Chan ED, Van TT, Antonio M, Ayorinde A, Kato-Maeda M, Nahid P, Leung AM, Yen A, Fingerlin TE, Kechris K, Strong M, Voskuil MI, Davis JL, Schoolnik GK. Adaptation of Mycobacterium tuberculosis to Impaired Host Immunity in HIV-Infected Patients. The Journal of infectious diseases 2016. PMID: 27534685


  24. Philip C. Hopewell, Midori Kato-Maeda, Joel D. Ernst. 35 Tuberculosis. Murray and Nadel\u0027s Textbook of Respiratory Medicine 2016. PMID:


  25. Xu J, Guttorp P, Kato-Maeda M, Minin VN. Likelihood-based inference for discretely observed birth-death-shift processes, with applications to evolution of mobile genetic elements. Biometrics 2015. PMID: 26148963


  26. Jayakumar A, Vittinghoff E, Segal MR, MacKenzie WR, Johnson JL, Gitta P, Saukkonen J, Anderson J, Weiner M, Engle M, Yoon C, Kato-Maeda M, Nahid P. Serum biomarkers of treatment response within a randomized clinical trial for pulmonary tuberculosis. Volume 95 of Issue 4. Tuberculosis (Edinburgh, Scotland) 2015. PMID: 26022314


  27. Choi JC, Jarlsberg LG, Grinsdale JA, Osmond DH, Higashi J, Hopewell PC, Kato-Maeda M. Reduced sensitivity of the QuantiFERON(®) test in diabetic patients with smear-negative tuberculosis. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2015. PMID: 25868028


  28. Srinivasan R, Karaoz U, Volegova M, MacKichan J, Kato-Maeda M, Miller S, Nadarajan R, Brodie EL, Lynch SV. Use of 16S rRNA gene for identification of a broad range of clinically relevant bacterial pathogens. Volume 10 of Issue 2. PloS one 2015. PMID: 25658760


  29. Chamie G, Wandera B, Marquez C, Kato-Maeda M, Kamya MR, Havlir DV, Charlebois ED. Identifying locations of recent TB transmission in rural Uganda: a multidisciplinary approach. Volume 20 of Issue 4. Tropical medicine & international health : TM & IH 2015. PMID: 25583212


  30. Coscolla M, Barry PM, Oeltmann JE, Koshinsky H, Shaw T, Cilnis M, Posey J, Rose J, Weber T, Fofanov VY, Gagneux S, Kato-Maeda M, Metcalfe JZ. Genomic epidemiology of multidrug-resistant Mycobacterium tuberculosis during transcontinental spread. Volume 212 of Issue 2. The Journal of infectious diseases 2015. PMID: 25601940


  31. Allison S. Rhines, Midori Kato-Maeda, Marcus W. Feldman. Model of the Effects of Improving TB Diagnosis on Infection Dynamics in Differing Demographic and HIV-Prevalence Scenarios. Journal of Tuberculosis Research 2015. PMID:


  32. Suwanpimolkul G, Grinsdale JA, Jarlsberg LG, Higashi J, Osmond DH, Hopewell PC, Kato-Maeda M. Association between diabetes mellitus and tuberculosis in United States-born and foreign-born populations in San Francisco. PloS one 2014. PMID: 25478954


  33. Budzik JM, Jarlsberg LG, Higashi J, Grinsdale J, Hopewell PC, Kato-Maeda M, Nahid P. Pyrazinamide resistance, Mycobacterium tuberculosis lineage and treatment outcomes in San Francisco, California. PloS one 2014. PMID: 24759760


  34. Farhat MR, Shapiro BJ, Kieser KJ, Sultana R, Jacobson KR, Victor TC, Warren RM, Streicher EM, Calver A, Sloutsky A, Kaur D, Posey JE, Plikaytis B, Oggioni MR, Gardy JL, Johnston JC, Rodrigues M, Tang PK, Kato-Maeda M, Borowsky ML, Muddukrishna B, Kreiswirth BN, Kurepina N, Galagan J, Gagneux S, Birren B, Rubin EJ, Lander ES, Sabeti PC, Murray M. Genomic analysis identifies targets of convergent positive selection in drug-resistant Mycobacterium tuberculosis. Nature genetics 2013. PMID: 23995135


  35. Comas I, Coscolla M, Luo T, Borrell S, Holt KE, Kato-Maeda M, Parkhill J, Malla B, Berg S, Thwaites G, Yeboah-Manu D, Bothamley G, Mei J, Wei L, Bentley S, Harris SR, Niemann S, Diel R, Aseffa A, Gao Q, Young D, Gagneux S. Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans. Nature genetics 2013. PMID: 23995134


  36. Anderson J, Jarlsberg LG, Grindsdale J, Osmond D, Kawamura M, Hopewell PC, Kato-Maeda M. Sublineages of lineage 4 (Euro-American) Mycobacterium tuberculosis differ in genotypic clustering. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2013. PMID: 23743309


  37. Bojorquez I, Barnes RF, Flood J, López-Gatell H, Garfein RS, Bäcker CE, Alpuche C, Vinetz JM, Catanzaro A, Kato-Maeda M, Rodwell TC. Multidrug-resistant tuberculosis among patients in Baja California, Mexico, and Hispanic patients in California. American journal of public health 2013. PMID: 23678924


  38. Suwanpimolkul G, Jarlsberg LG, Grinsdale JA, Osmond D, Kawamura LM, Hopewell PC, Kato-Maeda M. Molecular epidemiology of tuberculosis in foreign-born persons living in San Francisco. American journal of respiratory and critical care medicine 2013. PMID: 23471470


  39. Kato-Maeda M, Ho C, Passarelli B, Banaei N, Grinsdale J, Flores L, Anderson J, Murray M, Rose G, Kawamura LM, Pourmand N, Tariq MA, Gagneux S, Hopewell PC. Use of whole genome sequencing to determine the microevolution of Mycobacterium tuberculosis during an outbreak. PloS one 2013. PMID: 23472164


  40. Doss CR, Suchard MA, Holmes I, Kato-Maeda M, Minin VN. Fitting Birth-Death Processes to Panel Data with Applications to Bacterial DNA Fingerprinting. The annals of applied statistics 2013. PMID: 26702330


  41. Somashekar BS, Amin AG, Tripathi P, MacKinnon N, Rithner CD, Shanley CA, Basaraba R, Henao-Tamayo M, Kato-Maeda M, Ramamoorthy A, Orme IM, Ordway DJ, Chatterjee D. Metabolomic signatures in guinea pigs infected with epidemic-associated W-Beijing strains of Mycobacterium tuberculosis. Journal of proteome research 2012. PMID: 22873951


  42. Kato-Maeda M, Shanley CA, Ackart D, Jarlsberg LG, Shang S, Obregon-Henao A, Harton M, Basaraba RJ, Henao-Tamayo M, Barrozo JC, Rose J, Kawamura LM, Coscolla M, Fofanov VY, Koshinsky H, Gagneux S, Hopewell PC, Ordway DJ, Orme IM. Beijing sublineages of Mycobacterium tuberculosis differ in pathogenicity in the guinea pig. Clinical and vaccine immunology : CVI 2012. PMID: 22718126


  43. Dantes R, Metcalfe J, Kim E, Kato-Maeda M, Hopewell PC, Kawamura M, Nahid P, Cattamanchi A. Impact of isoniazid resistance-conferring mutations on the clinical presentation of isoniazid monoresistant tuberculosis. Volume 7 of Issue 5. PloS one 2012. PMID: 22649569


  44. Kato-Maeda M, Nahid P. Mycobacterium tuberculosis lineage--what's in your lungs? Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2012. PMID: 22198990


  45. Comas I, Borrell S, Roetzer A, Rose G, Malla B, Kato-Maeda M, Galagan J, Niemann S, Gagneux S. Whole-genome sequencing of rifampicin-resistant Mycobacterium tuberculosis strains identifies compensatory mutations in RNA polymerase genes. Nature genetics 2011. PMID: 22179134


  46. Worjoloh A, Kato-Maeda M, Osmond D, Freyre R, Aziz N, Cohan D. Interferon gamma release assay compared with the tuberculin skin test for latent tuberculosis detection in pregnancy. Obstetrics and gynecology 2011. PMID: 22105266


  47. Worodria W, Anderson J, Cattamanchi A, Davis JL, den Boon S, Andama A, Yoo SD, Joloba M, Huang L, Kato-Maeda M. The role of speciation in positive Lowenstein-Jensen culture isolates from a high tuberculosis burden country. Volume 6 of Issue 11. PloS one 2011. PMID: 22073241


  48. Kato-Maeda M, Metcalfe JZ, Flores L. Genotyping of Mycobacterium tuberculosis: application in epidemiologic studies. Volume 6 of Issue 2. Future microbiology 2011. PMID: 21366420


  49. Kato-Maeda M, Gagneux S, Flores LL, Kim EY, Small PM, Desmond EP, Hopewell PC. Strain classification of Mycobacterium tuberculosis: congruence between large sequence polymorphisms and spoligotypes. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2011. PMID: 21276309


  50. Metcalfe JZ, Kim EY, Lin SY, Cattamanchi A, Oh P, Flood J, Hopewell PC, Kato-Maeda M. Determinants of multidrug-resistant tuberculosis clusters, California, USA, 2004-2007. Volume 16 of Issue 9. Emerging infectious diseases 2010. PMID: 20735924


  51. Nahid P, Bliven EE, Kim EY, Mac Kenzie WR, Stout JE, Diem L, Johnson JL, Gagneux S, Hopewell PC, Kato-Maeda M. Influence of M. tuberculosis lineage variability within a clinical trial for pulmonary tuberculosis. PloS one 2010. PMID: 20505778


  52. Kato-Maeda M, Kim EY, Flores L, Jarlsberg LG, Osmond D, Hopewell PC. Differences among sublineages of the East-Asian lineage of Mycobacterium tuberculosis in genotypic clustering. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2010. PMID: 20392345


  53. Kim EY, Nahid P, Hopewell PC, Kato-Maeda M. Novel hot spot of IS6110 insertion in Mycobacterium tuberculosis. Journal of clinical microbiology 2010. PMID: 20147648


  54. Philip C. Hopewell, Midori Kato-Maeda. Chapter 34 Tuberculosis. Murray and Nadel\u0027s Textbook of Respiratory Medicine 2010. PMID:


  55. Flores L, Jarlsberg LG, Kim EY, Osmond D, Grinsdale J, Kawamura M, Desmond E, Hopewell PC, Kato-Maeda M. Comparison of restriction fragment length polymorphism with the polymorphic guanine-cytosine-rich sequence and spoligotyping for differentiation of Mycobacterium tuberculosis isolates with five or fewer copies of IS6110. Journal of clinical microbiology 2009. PMID: 20032250


  56. Marquina-Castillo B, García-García L, Ponce-de-León A, Jimenez-Corona ME, Bobadilla-Del Valle M, Cano-Arellano B, Canizales-Quintero S, Martinez-Gamboa A, Kato-Maeda M, Robertson B, Young D, Small P, Schoolnik G, Sifuentes-Osornio J, Hernandez-Pando R. Virulence, immunopathology and transmissibility of selected strains of Mycobacterium tuberculosis in a murine model. Immunology 2008. PMID: 19191912


  57. Martinez-Gamboa A, Ponce-de-Leon A, Galindo-Fraga A, Bobadilla-del-Valle M, Kato-Maeda M, Robertson BD, Young DB, Small PM, Sifuentes-Osornio J. Molecular analysis of Mycobacterium tuberculosis strains with an intact pks15/1 gene in a rural community of Mexico. Archives of medical research 2008. PMID: 18996296


  58. Wu B, Huang C, Kato-Maeda M, Hopewell PC, Daley CL, Krensky AM, Clayberger C. IL-24 modulates IFN-gamma expression in patients with tuberculosis. Immunology letters 2007. PMID: 18199488


  59. Wu B, Huang C, Kato-Maeda M, Hopewell PC, Daley CL, Krensky AM, Clayberger C. IL-9 is associated with an impaired Th1 immune response in patients with tuberculosis. Clinical immunology (Orlando, Fla.) 2007. PMID: 18032114


  60. Flores L, Van T, Narayanan S, DeRiemer K, Kato-Maeda M, Gagneux S. Large sequence polymorphisms classify Mycobacterium tuberculosis strains with ancestral spoligotyping patterns. Journal of clinical microbiology 2007. PMID: 17699643


  61. Wu B, Huang C, Garcia L, Ponce de Leon A, Osornio JS, Bobadilla-del-Valle M, Ferreira L, Canizales S, Small P, Kato-Maeda M, Krensky AM, Clayberger C. Unique gene expression profiles in infants vaccinated with different strains of Mycobacterium bovis bacille Calmette-Guerin. Infection and immunity 2007. PMID: 17502394


  62. Wu B, Huang C, Kato-Maeda M, Hopewell PC, Daley CL, Krensky AM, Clayberger C. Messenger RNA expression of IL-8, FOXP3, and IL-12beta differentiates latent tuberculosis infection from disease. Journal of immunology (Baltimore, Md. : 1950) 2007. PMID: 17339466


  63. Aga RS, Fair E, Abernethy NF, Deriemer K, Paz EA, Kawamura LM, Small PM, Kato-Maeda M. Microevolution of the direct repeat locus of Mycobacterium tuberculosis in a strain prevalent in San Francisco. Journal of clinical microbiology 2006. PMID: 16597893


  64. Gagneux S, DeRiemer K, Van T, Kato-Maeda M, de Jong BC, Narayanan S, Nicol M, Niemann S, Kremer K, Gutierrez MC, Hilty M, Hopewell PC, Small PM. Variable host-pathogen compatibility in Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America 2006. PMID: 16477032


  65. Freeman R, Kato-Maeda M, Hauge KA, Horan KL, Oren E, Narita M, Wallis CK, Cave D, Nolan CM, Small PM, Cangelosi GA. Use of rapid genomic deletion typing to monitor a tuberculosis outbreak within an urban homeless population. Journal of clinical microbiology 2005. PMID: 16272485


  66. Mostowy S, Onipede A, Gagneux S, Niemann S, Kremer K, Desmond EP, Kato-Maeda M, Behr M. Genomic analysis distinguishes Mycobacterium africanum. Journal of clinical microbiology 2004. PMID: 15297503


  67. Tsolaki AG, Hirsh AE, DeRiemer K, Enciso JA, Wong MZ, Hannan M, Goguet de la Salmoniere YO, Aman K, Kato-Maeda M, Small PM. Functional and evolutionary genomics of Mycobacterium tuberculosis: insights from genomic deletions in 100 strains. Proceedings of the National Academy of Sciences of the United States of America 2004. PMID: 15024109


  68. Kato-Maeda M, Bautista-Alavez A, Rolón-Montes-de-Oca AL, Ramos-Hinojosa A, Ponce-de-León A, Bobadilla-del-Valle M, Ruiz-Palacios G, Sifuentes-Osornio J. [Increasing trend of antimicrobial drug-resistance in organisms causing bacteremia at a tertiary-care hospital: 1995 to 2000]. Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 2003. PMID: 15011727


  69. Bobadilla-del-Valle M, Ponce-de-León A, Kato-Maeda M, Hernández-Cruz A, Calva-Mercado JJ, Chávez-Mazari B, Caballero-Rivera BA, Nolasco-García JC, Sifuentes-Osornio J. Comparison of sodium carbonate, cetyl-pyridinium chloride, and sodium borate for preservation of sputa for culture of Mycobacterium tuberculosis. Journal of clinical microbiology 2003. PMID: 12958303


  70. Navarro-Alvarez S, Bobadilla del Valle M, Kato-Maeda M. Screening for tuberculosis in pregnancy. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2002. PMID: 12445993


  71. García-García Mde L, Ponce-De-León A, García-Sancho MC, Ferreyra-Reyes L, Palacios-Martínez M, Fuentes J, Kato-Maeda M, Bobadilla M, Small P, Sifuentes-Osornio J. Tuberculosis-related deaths within a well-functioning DOTS control program. Emerging infectious diseases 2002. PMID: 12453365


  72. Kato-Maeda M, Mohar A. [Genetic material: instruction manual for the management of disease; breast cancer, for example]. Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 2002. PMID: 12415951


  73. Kato-Maeda M, Gao Q, Small PM. Microarray analysis of pathogens and their interaction with hosts. Cellular microbiology 2001. PMID: 11696031


  74. Bobadilla-del-Valle M, Ponce-de-Leon A, Arenas-Huertero C, Vargas-Alarcon G, Kato-Maeda M, Small PM, Couary P, Ruiz-Palacios GM, Sifuentes-Osornio J. rpoB Gene mutations in rifampin-resistant Mycobacterium tuberculosis identified by polymerase chain reaction single-stranded conformational polymorphism. Emerging infectious diseases 2001. PMID: 11747730


  75. Kato-Maeda M, Small PM. User's guide to tuberculosis resources on the internet. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2001. PMID: 11340530


  76. Kato-Maeda M, Rhee JT, Gingeras TR, Salamon H, Drenkow J, Smittipat N, Small PM. Comparing genomes within the species Mycobacterium tuberculosis. Genome research 2001. PMID: 11282970


  77. Kato-Maeda M, Bifani PJ, Kreiswirth BN, Small PM. The nature and consequence of genetic variability within Mycobacterium tuberculosis. The Journal of clinical investigation 2001. PMID: 11238552


  78. Salamon H, Kato-Maeda M, Small PM, Drenkow J, Gingeras TR. Detection of deleted genomic DNA using a semiautomated computational analysis of GeneChip data. Genome research 2000. PMID: 11116098


  79. Hugh Salamon, Midori Kato-Maeda, Peter M. Small, Jorg Drenkow, Thomas R. Gingeras. Detection of Deleted Genomic DNA Using a Semiautomated Computational Analysis of GeneChip Data. 2000. PMID:


  80. Kato-Maeda M, Ponce-de-León S, Sifuentes-Osornio J, Rangel-Frausto MS, Calva-Mercado J, Infante-Surez L, Villareal FM, Ponce-de-León S. Bloodborne viral infections in patients attending an emergency room in Mexico City: estimate of seroconversion probability in healthcare workers after an occupational exposure. Infection control and hospital epidemiology 2000. PMID: 11001265


  81. Kato-Maeda M, Small PM. How molecular epidemiology has changed what we know about tuberculosis. The Western journal of medicine 2000. PMID: 10778380


  82. Kato-Maeda M, Sifuentes-Osornio J, Bobadilla-del-Valle M, Ruiz-Palacios GM, Ponce-de-León A. Drug resistance among acid-fast bacilli. Lancet (London, England) 1999. PMID: 10335816


  83. Ponce-de-León S, Lisker-Melman M, Kato-Maeda M, Gamboa-Domínguez A, Ontiveros C, Behrens RH, González-Ruiz A. Trypanosoma brucei rhodesiense infection imported to Mexico from a tourist resort in Kenya. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1996. PMID: 8909868