Matthew Spinelli, MD, MAS

Assistant Adjunct Professor

I am HIV/ID physician with training in implementation science methods who uses these approaches to support pre-exposure prophylaxis (PrEP) implementation, PrEP/HIV ART adherence, and PrEP persistence/HIV retention in care. A key tool we are using in this work is a point-of-care urine tenofovir test that can provide real-time adherence information to clinicians to drive adherence interventions. More recently, I lead projects on development of adherence measurement techniques for doxycycline post-exposure prophylaxis, including a directly observed therapy randomized trial. In terms of educational initiatives, I am the co-director of the Implementation Science Short Course and the Individual-Level Intervention Design course in the UCSF Department of Epidemiology. As an HIV/ID clinician, I serve as the PrEP Medical Lead for the Ward 86 Clinic. Finally, I am a member of the Partnership for Research in Implementation Science for Equity, a collaboration between the SF Department of Public Health and UCSF that seeks to use implementation science methods to advance health equity.

Education
Fellowship, 2020 - HIV Clinical and Research Fellowship, University of California, San Francisco
M.A.S., 2019 - Epidemiology & Implementation Science, University of California, San Francisco
Fellowship, 2018 - Infectious Diseases, University of California, San Francisco
Residency, 2016 - Internal Medicine, University of California, San Francisco
M.D., 2013 - Medicine, Mount Sinai School of Medicine
B.A., 2008 - Italian Literature, Columbia University
Publications

  1. Spinelli MA, Bisom-Rapp E, Heise MJ, Camp C, Appa A, Liu AY, Sassaman K, Shiels M, Mayorga-Munoz F, Chimezie A, Nguyen J, Oskarsson J, Gandhi M. High Retention and Adherence with Rapid Long-Acting Injectable PrEP Implementation in an Urban Safety-Net Clinic Population. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2024. PMID: 39484783


  2. Spinelli MA, Ngure K, Gandhi M. Preexposure Prophylaxis (PrEP) for HIV. JAMA 2024. PMID: 39401050


  3. Spinelli MA, Johnson MO, Lisha NE, Jain JP, Moreira CV, Glidden DV, Burkholder GA, Crane HM, Jacobson JM, Cachay ER, Mayer KH, Napravnik S, Moore RD, Gandhi M, Christopoulos KA. Prevalence and Correlates of SARS-CoV-2 Vaccine Uptake and Hesitancy Among People With HIV Across the United States. Journal of acquired immune deficiency syndromes (1999) 2024. PMID: 39116328


  4. Jain JP, Heise MJ, Lisha NE, Moreira CH, Glidden DV, Burkholder GA, Crane HM, Jacobson JM, Cachay ER, Mayer KH, Napravnik S, Moore RD, Dawson-Rose C, Johnson MO, Christopoulos KA, Gandhi M, Spinelli MA. Impact of the Coronavirus Disease 2019 Pandemic on Substance Use Disorder Risk Among People Living With Human Immunodeficiency Virus (HIV) Enrolled in HIV Care in the United States: An Interrupted Time Series Analysis. Open forum infectious diseases 2024. PMID: 39252870


  5. Shah P, Spinelli M, Irungu E, Kabuti R, Ngurukiri P, Babu H, Kungu M, Champions TMFS, Nyabuto C, Mahero A, Devries K, Kyegombe N, Medley GF, Gafos M, Seeley J, Weiss HA, Kaul R, Gandhi M, Beattie TS, Kimani J. Factors Associated with Usage of Oral-PrEP among Female Sex Workers in Nairobi, Kenya, Assessed by Self-Report and a Point-of-Care Urine Tenofovir Immunoassay. AIDS and behavior 2024. PMID: 39136824


  6. Gandhi M, Glidden DV, Chakravarty D, Wang G, Biwott C, Mogere P, Maina G, Njeru I, Kiptinness C, Okello P, Spinelli MA, Chatterjee P, Velloza J, Ogello V, Medina-Marino A, Okochi H, Mugo NR, Ngure K. Impact of a point-of-care urine tenofovir assay on adherence to HIV pre-exposure prophylaxis among women in Kenya: a randomised pilot trial. The lancet. HIV 2024. PMID: 38976993


  7. Hickey MD, Grochowski J, Mayorga-Munoz F, Oskarsson J, Imbert E, Spinelli M, Szumowski JD, Appa A, Koester K, Dauria EF, McNulty M, Colasanti J, Havlir DV, Gandhi M, Christopoulos KA. Identifying Implementation Determinants and Strategies for Long-Acting Injectable Cabotegravir-Rilpivirine in People with HIV Who Are Virally Unsuppressed. Journal of acquired immune deficiency syndromes (1999) 2024. PMID: 38534179


  8. Martinson T, Montoya R, Moreira C, Kuncze K, Sassaman K, Heise MJ, Glidden DV, Amico KR, Arnold EA, Buchbinder SP, Ewart LD, Carrico A, Wang G, Okochi H, Scott HM, Gandhi M, Spinelli MA. Point-of-care urine tenofovir test predicts future HIV pre-exposure prophylaxis discontinuation among young users. AIDS (London, England) 2024. PMID: 38905507


  9. Spinelli MA, Christopoulos KA, Moreira CV, Jain JP, Lisha N, Glidden DV, Burkholder GA, Crane HM, Shapiro AE, Jacobson JM, Cachay ER, Mayer KH, Napravnik S, Moore RD, Gandhi M, Johnson MO. Viral Suppression Trajectories Destabilized After Coronavirus Disease 2019 Among US People With Human Immunodeficiency Virus: An Interrupted Time Series Analysis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2023. PMID: 37963086


  10. Peluso MJ, Swank ZN, Goldberg SA, Lu S, Dalhuisen T, Borberg E, Senussi Y, Luna MA, Chang Song C, Clark A, Zamora A, Lew M, Viswanathan B, Huang B, Anglin K, Hoh R, Hsue PY, Durstenfeld MS, Spinelli MA, Glidden DV, Henrich TJ, Kelly JD, Deeks SG, Walt DR, Martin JN. Plasma-based antigen persistence in the post-acute phase of COVID-19. The Lancet. Infectious diseases 2024. PMID: 38604216


  11. Martinson T, Nwogu-Attah J, Spinelli M, Gandhi M. Low-cost urine tenofovir assay to triage dolutegravir resistance testing. The lancet. HIV 2024. PMID: 38461845


  12. Spinelli M, Gandhi M. Point-of-care urine tenofovir monitoring of adherence to drive interventions for HIV treatment and prevention. Expert review of molecular diagnostics 2024. PMID: 38353417


  13. Peluso MJ, Swank ZN, Goldberg SA, Lu S, Dalhuisen T, Borberg E, Senussi Y, Luna MA, Chang Song C, Clark A, Zamora A, Lew M, Viswanathan B, Huang B, Anglin K, Hoh R, Hsue PY, Durstenfeld MS, Spinelli MA, Glidden DV, Henrich TJ, Kelly JD, Deeks SG, Walt DR, Martin JN. Plasma-based antigen persistence in the post-acute phase of SARS-CoV-2 infection. medRxiv : the preprint server for health sciences 2023. PMID: 37961239


  14. Stewart J, Oware K, Donnell D, Violette LR, Odoyo J, Soge OO, Scoville CW, Omollo V, Mogaka FO, Sesay FA, McClelland RS, Spinelli M, Gandhi M, Bukusi EA, Baeten JM, dPEP Kenya Study Team. Doxycycline Prophylaxis to Prevent Sexually Transmitted Infections in Women. The New England journal of medicine 2023. PMID: 38118022


  15. Herbertson EC, Lahiri CD, Olugbake OA, Soremekun RO, Spinelli MA, Gandhi M. Adherence determination using urine-tenofovir point-of-care testing and pharmacy refill records: A cross-sectional study. Medicine 2023. PMID: 38013290


  16. Landovitz RJ, Hanscom BS, Clement ME, Tran HV, Kallas EG, Magnus M, Sued O, Sanchez J, Scott H, Eron JJ, Del Rio C, Fields SD, Marzinke MA, Eshleman SH, Donnell D, Spinelli MA, Kofron RM, Berman R, Piwowar-Manning EM, Richardson PA, Sullivan PA, Lucas JP, Anderson PL, Hendrix CW, Adeyeye A, Rooney JF, Rinehart AR, Cohen MS, McCauley M, Grinsztejn B, HPTN 083 Study Team. Efficacy and safety of long-acting cabotegravir compared with daily oral tenofovir disoproxil fumarate plus emtricitabine to prevent HIV infection in cisgender men and transgender women who have sex with men 1 year after study unblinding: a secondary anal The lancet. HIV 2023. PMID: 37952550


  17. Durstenfeld MS, Peluso MJ, Spinelli MA, Li D, Hoh R, Chenna A, Yee B, Winslow J, Petropoulos C, Gandhi M, Henrich TJ, Aras MA, Long CS, Deeks SG, Hsue PY. Association of SARS-CoV-2 Infection and Cardiopulmonary Long COVID With Exercise Capacity and Chronotropic Incompetence Among People With HIV. Journal of the American Heart Association 2023. PMID: 37830367


  18. Mustanski B, Ryan DT, Spinelli MA, Gandhi M, Newcomb ME. Urine point-Of-care tenofovir test demonstrates strong predictive clinical and research utility. AIDS (London, England) 2023. PMID: 37696260


  19. Mars SG, Spinelli MA, Ondocsin J, Koester KA, Rodriguez ES, Jain J, Arreguin M, Johnson MO, Gandhi M. Pandemic expertise: qualitative findings on the experiences of living with HIV during the COVID-19 pandemic. AIDS care 2023. PMID: 37621106


  20. Durstenfeld MS, Peluso MJ, Spinelli MA, Li D, Hoh R, Gandhi M, Henrich TJ, Aras MA, Long CS, Deeks SG, Hsue PY. Association of SARS-CoV-2 Infection and Cardiopulmonary Long COVID with Exercise Capacity and Chronotropic Incompetence among People with HIV. medRxiv : the preprint server for health sciences 2023. PMID: 37205522


  21. Spinelli M, Gandhi M, Riva A. The intertwined epidemics of HIV and COVID-19 - emerging data and responses. Current opinion in HIV and AIDS 2023. PMID: 37144612


  22. Johnson KA, Okochi H, Arreguin M, Watabe J, Glidden DV, Chattopadhyay A, Imbert E, Hickey MD, Gandhi M, Spinelli M. Brief Report: Urine Tenofovir Levels Strongly Correlate with Virologic Suppression in Patients with HIV on Tenofovir Alafenamide-Based Antiretroviral Therapy. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022. PMID: 36253952


  23. Mccluskey SM, Govender K, Adamson J, Gandhi M, Spinelli MA, Moosa MY, Muyindike W, Moodley P, Pillay M, Masette G, Sunpath H, Pillay S, Chen G, Hedt-Gauthier B, Marconi VC, Siedner MJ. Point-of-care urine tenofovir testing to predict HIV drug resistance among individuals with virologic failure. AIDS (London, England) 2023. PMID: 36928169


  24. Peluso MJ, Deveau TM, Munter SE, Ryder DM, Buck AM, Beck-Engeser G, Chan F, Lu S, Goldberg SA, Hoh R, Tai V, Torres L, Iyer NS, Deswal M, Ngo LH, Buitrago M, Rodriguez AE, Chen JY, Yee BC, Chenna A, Winslow JW, Petropoulos CJ, Deitchman AN, Hellmuth J, Spinelli MA, Durstenfeld MS, Hsue PY, Kelly JD, Martin JN, Deeks SG, Hunt PW, Henrich TJ. Impact of pre-existing chronic viral infection and reactivation on the development of long COVID. The Journal of clinical investigation 2022. PMID: 36454631


  25. Spinelli MA, Peluso MJ, Lynch KL, Yun C, Glidden DV, Henrich TJ, Deeks SG, Gandhi M. Differences in Post-mRNA Vaccination SARS-CoV-2 IgG Concentrations and Surrogate Virus Neutralization Test Response by HIV Status and Type of Vaccine: a Matched Case-Control Observational Study. 2021. PMID: 34864962


  26. Spinelli MA, Le Tourneau N, Glidden DV, Hsu L, Hickey MD, Imbert E, Arreguin M, Jain JP, Oskarsson JJ, Buchbinder SP, Johnson MO, Havlir D, Christopoulos KA, Gandhi M. Impact of Multi-Component Support Strategies on HIV Virologic Suppression Rates during COVID-19: An Interrupted Time Series Analysis. 2022. PMID: 35245934


  27. van Zyl G, Jennings L, Kellermann T, Nkantsu Z, Cogill D, van Schalkwyk M, Spinelli M, Decloedt E, Orrell C, Gandhi M. Urine tenofovir-monitoring predicts HIV viremia in patients treated with high genetic-barrier regimens. AIDS (London, England) 2022. PMID: 36305182


  28. Spinelli MA, Jones BLH, Gandhi M. COVID-19 Outcomes and Risk Factors Among People Living with HIV. Current HIV/AIDS reports 2022. PMID: 35930187


  29. Peluso MJ, Deveau TM, Munter SE, Ryder D, Buck A, Beck-Engeser G, Chan F, Lu S, Goldberg SA, Hoh R, Tai V, Torres L, Iyer NS, Deswal M, Ngo LH, Buitrago M, Rodriguez A, Chen JY, Yee BC, Chenna A, Winslow JW, Petropoulos CJ, Deitchman AN, Hellmuth J, Spinelli MA, Durstenfeld MS, Hsue PY, Kelly JD, Martin JN, Deeks SG, Hunt PW, Henrich TJ. Impact of Pre-Existing Chronic Viral Infection and Reactivation on the Development of Long COVID. medRxiv : the preprint server for health sciences 2022. PMID: 35898346


  30. Peluso MJ, Spinelli MA, Deveau TM, Forman CA, Munter SE, Mathur S, Tang AF, Lu S, Goldberg SA, Arreguin MI, Hoh R, Tai V, Chen JY, Martinez EO, Yee BC, Chenna A, Winslow JW, Petropoulos CJ, Sette A, Weiskopf D, Kumar N, Lynch KL, Hunt PW, Durstenfeld MS, Hsue PY, Kelly JD, Martin JN, Glidden DV, Gandhi M, Deeks SG, Rutishauser RL, Henrich TJ. Post-acute sequelae and adaptive immune responses in people living with HIV recovering from SARS-COV-2 infection. AIDS (London, England) 2022. PMID: 35866847


  31. Conroy AA, McKenna S, Ruark A, Neilands TB, Spinelli M, Gandhi M. Relationship Dynamics are Associated with Self-Reported Adherence but not an Objective Adherence Measure in Malawi. 2022. PMID: 35507094


  32. Spinelli MA, Grinsztejn B, Landovitz RJ. Promises and challenges: cabotegravir for preexposure prophylaxis. Current opinion in HIV and AIDS 2022. PMID: 35762372


  33. Jennings L, Kellermann T, Spinelli MA, Nkantsu Z, Cogill D, van Schalkwyk M, Decloedt E, van Zyl G, Orrell C, Gandhi M. Drug resistance, rather than low tenofovir levels in blood or urine, is associated with tenofovir, emtricitabine and efavirenz (TEE) failure in resource-limited settings. 2021. PMID: 34779228


  34. Peluso MJ, Kelly JD, Lu S, Goldberg SA, Davidson MC, Mathur S, Durstenfeld MS, Spinelli MA, Hoh R, Tai V, Fehrman EA, Torres L, Hernandez Y, Williams MC, Arreguin MI, Ngo LH, Deswal M, Munter SE, Martinez EO, Anglin KA, Romero MD, Tavs J, Rugart PR, Chen JY, Sans HM, Murray VW, Ellis PK, Donohue KC, Massachi JA, Weiss JO, Mehdi I, Pineda-Ramirez J, Tang AF, Wenger MA, Assenzio MT, Yuan Y, Krone MR, Rutishauser RL, Rodriguez-Barraquer I, Greenhouse B, Sauceda JA, Gandhi M, Scheffler AW, Hsue PY, Henrich TJ, Deeks SG, Martin JN. Persistence, Magnitude, and Patterns of Postacute Symptoms and Quality of Life Following Onset of SARS-CoV-2 Infection: Cohort Description and Approaches for Measurement. 2021. PMID: 35106317


  35. Santiago-Rodriguez EI, Maiorana A, Peluso MJ, Hoh R, Tai V, Fehrman EA, Hernandez Y, Torres L, Spinelli MA, Gandhi M, Kelly JD, Martin JN, Henrich TJ, Deeks SG, Sauceda JA. Characterizing the COVID-19 Illness Experience to Inform the Study of Post-acute Sequelae and Recovery. 2021. PMID: 34918211


  36. Matthew A Spinelli, Michael J Peluso, Kara Lynch, Cassandra Yun, David V Glidden, Timothy J Henrich, Steve Deeks, Monica Gandhi. LB8. Lower SARS-CoV-2 IgG and Pseudovirus Neutralization Titers Post-mRNA Vaccination among People Living with HIV. 2021. PMID:


  37. Spinelli MA, Brown LB, Glidden DV, Hunter K, Martin-Tuite P, Zheng J, Sera C, Havlir D, Buchbinder SP, Gandhi M. SARS-CoV-2 incidence, testing rates, and severe COVID-19 outcomes among people with and without HIV. 2021. PMID: 34870933


  38. Matthew A. Spinelli, Lillian B. Brown, David V. Glidden, Kyle Hunter, Patrick Martin-Tuite, James Zheng, Curtis Sera, Diane Havlir, Susan P. Buchbinder, Monica Gandhi. SARS-CoV-2 incidence, testing rates, and severe COVID-19 outcomes among people with and without HIV. AIDS 2021. PMID:


  39. Johnson KA, Okochi H, Glidden DV, Gandhi M, Spinelli M. Brief Report: No Difference in Urine Tenofovir Levels in Patients Living With HIV on Unboosted Versus Dose-Adjusted Boosted Tenofovir Alafenamide. Journal of acquired immune deficiency syndromes (1999) 2021. PMID: 33990489


  40. Peluso MJ, Deitchman AN, Torres L, Iyer NS, Munter SE, Nixon CC, Donatelli J, Thanh C, Takahashi S, Hakim J, Turcios K, Janson O, Hoh R, Tai V, Hernandez Y, Fehrman EA, Spinelli MA, Gandhi M, Trinh L, Wrin T, Petropoulos CJ, Aweeka FT, Rodriguez-Barraquer I, Kelly JD, Martin JN, Deeks SG, Greenhouse B, Rutishauser RL, Henrich TJ. Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms. Cell reports 2021. PMID: 34358460


  41. Spinelli MA, Glidden DV, Gennatas ED, Rutherford GW, Gandhi M. Effectiveness of Adding a Mask Recommendation to Other Public Health Measures. Annals of internal medicine 2021. PMID: 34399080


  42. Peluso MJ, Takahashi S, Hakim J, Kelly JD, Torres L, Iyer NS, Turcios K, Janson O, Munter SE, Thanh C, Donatelli J, Nixon CC, Hoh R, Tai V, Fehrman EA, Hernandez Y, Spinelli MA, Gandhi M, Palafox MA, Vallari A, Rodgers MA, Prostko J, Hackett J, Trinh L, Wrin T, Petropoulos CJ, Chiu CY, Norris PJ, DiGermanio C, Stone M, Busch MP, Elledge SK, Zhou XX, Wells JA, Shu A, Kurtz TW, Pak JE, Wu W, Burbelo PD, Cohen JI, Rutishauser RL, Martin JN, Deeks SG, Henrich TJ, Rodriguez-Barraquer I, Greenhouse B. SARS-CoV-2 antibody magnitude and detectability are driven by disease severity, timing, and assay. Science advances 2021. PMID: 34330709


  43. DeJong C, Spinelli MA, Okochi H, Gandhi M. Tenofovir-based PrEP for COVID-19: an untapped opportunity? AIDS (London, England) 2021. PMID: 33710026


  44. Spinelli MA. SARS-CoV-2 vaccination in people with HIV. 2021. PMID: 34153265


  45. Spinelli MA, Lowery B, Shuford JA, Spindler J, Kearney MF, McFarlane JR, McDonald C, Okochi H, Phung N, Kuncze K, Jee K, Johannessen D, Anderson PL, Smith DK, Defechereux P, Grant RM, Gandhi M. Use of Drug-Level Testing and Single-Genome Sequencing to Unravel a Case of HIV Seroconversion on PrEP. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2020. PMID: 32686825


  46. Spinelli MA, Lynch KL, Yun C, Glidden DV, Peluso MJ, Henrich TJ, Gandhi M, Brown LB. SARS-CoV-2 seroprevalence, and IgG concentration and pseudovirus neutralising antibody titres after infection, compared by HIV status: a matched case-control observational study. The lancet. HIV 2021. PMID: 33933189


  47. Johnson KA, Niu X, Glidden DV, Castillo-Mancilla JR, Yager J, MaWhinney S, Morrow M, Okochi H, Cressey TR, Drain PK, Gandhi M, Anderson PL, Spinelli MA. Lower Urine Tenofovir Concentrations Among Individuals Taking Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate: Implications for Point-of-Care Testing. Open forum infectious diseases 2021. PMID: 34285929


  48. Spinelli MA, Rutherford G, Gandhi M. Lowering SARS-CoV-2 viral load might affect transmission but not disease severity in secondary cases - Authors' reply. The Lancet. Infectious diseases 2021. PMID: 33864804


  49. Okochi H, Louie A, Phung N, Zhang K, Tallerico RM, Kuncze K, Spinelli MA, Koss CA, Benet LZ, Gandhi M. Tenofovir and emtricitabine concentrations in hair are comparable between individuals on tenofovir disoproxil fumarate versus tenofovir alafenamide-based ART. Drug testing and analysis 2021. PMID: 33742745


  50. Santiago-Rodriguez EI, Maiorana A, Peluso MJ, Hoh R, Tai V, Fehrman EA, Hernandez Y, Torres L, Spinelli MA, Gandhi M, Kelly JD, Martin JN, Henrich TJ, Deeks SG, Sauceda JA. Characterizing the COVID-19 illness experience to inform the study of post-acute sequelae and recovery: a qualitative study. medRxiv : the preprint server for health sciences 2021. PMID: 33758881


  51. Spinelli MA, Hessol NA, Schwarcz SK, Scheer S, Gandhi M, Chin Hsu L. Disparities in Integrase Inhibitor Usage in the Modern HIV Treatment Era: A Population-Based Study in a US City. Open forum infectious diseases 2021. PMID: 34250184


  52. Peluso MJ, Kelly JD, Lu S, Goldberg SA, Davidson MC, Mathur S, Durstenfeld MS, Spinelli MA, Hoh R, Tai V, Fehrman EA, Torres L, Hernandez Y, Williams MC, Arreguin MI, Bautista JA, Ngo LH, Deswal M, Munter SE, Martinez EO, Anglin KA, Romero MD, Tavs J, Rugart PR, Chen JY, Sans HM, Murray VW, Ellis PK, Donohue KC, Massachi JA, Weiss JO, Mehdi I, Pineda-Ramirez J, Tang AF, Wenger M, Assenzio M, Yuan Y, Krone M, Rutishauser RL, Rodriguez-Barraquer I, Greenhouse B, Sauceda JA, Gandhi M, Hsue PY, Henrich TJ, Deeks SG, Martin JN. Rapid implementation of a cohort for the study of post-acute sequelae of SARS-CoV-2 infection/COVID-19. medRxiv : the preprint server for health sciences 2021. PMID: 33758895


  53. Peluso MJ, Takahashi S, Hakim J, Kelly JD, Torres L, Iyer NS, Turcios K, Janson O, Munter SE, Thanh C, Nixon CC, Hoh R, Tai V, Fehrman EA, Hernandez Y, Spinelli MA, Gandhi M, Palafox MA, Vallari A, Rodgers MA, Prostko J, Hackett J, Trinh L, Wrin T, Petroplolous CJ, Chiu CY, Norris PJ, DiGermanio C, Stone M, Busch MP, Elledge SK, Zhou XX, Wells JA, Shu A, Kurtz TW, Pak JE, Wu W, Burbelo PD, Cohen JI, Rutishauser RL, Martin JN, Deeks SG, Henrich TJ, Rodriguez-Barraquer I, Greenhouse B. SARS-CoV-2 antibody magnitude and detectability are driven by disease severity, timing, and assay. medRxiv : the preprint server for health sciences 2021. PMID: 33688675


  54. Peluso MJ, Deitchman AN, Torres L, Iyer NS, Nixon CC, Munter SE, Donatelli J, Thanh C, Takahashi S, Hakim J, Turcios K, Janson O, Hoh R, Tai V, Hernandez Y, Fehrman E, Spinelli MA, Gandhi M, Trinh L, Wrin T, Petropoulos CJ, Aweeka FT, Rodriguez-Barraquer I, Kelly JD, Martin JN, Deeks SG, Greenhouse B, Rutishauser RL, Henrich TJ. Long-Term SARS-CoV-2-Specific Immune and Inflammatory Responses Across a Clinically Diverse Cohort of Individuals Recovering from COVID-19. medRxiv : the preprint server for health sciences 2021. PMID: 33688685


  55. Spinelli MA, Glidden DV, Gennatas ED, Bielecki M, Beyrer C, Rutherford G, Chambers H, Goosby E, Gandhi M. Importance of non-pharmaceutical interventions in lowering the viral inoculum to reduce susceptibility to infection by SARS-CoV-2 and potentially disease severity. The Lancet. Infectious diseases 2021. PMID: 33631099


  56. Schwarcz S, Hessol NA, Spinelli MA, Hsu LC, Wlodarczyk D, Tulsky J, Newman MD, Buchbinder SP. Sensitivity and Specificity of the National Death Index for Multiple Causes of Death in People With HIV. Volume 136 of Issue 5. Public health reports (Washington, D.C. : 1974) 2021. PMID: 33541227


  57. Stalter RM, Baeten JM, Donnell D, Spinelli MA, Glidden DV, Rodrigues WC, Wang G, Vincent M, Mugo N, Mujugira A, Marzinke M, Hendrix C, Gandhi M, Partners PrEP Study Team. Urine Tenofovir Levels Measured Using a Novel Immunoassay Predict Human Immunodeficiency Virus Protection. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2021. PMID: 33527128


  58. Brown LB, Spinelli MA, Gandhi M. The interplay between HIV and COVID-19: summary of the data and responses to date. Current opinion in HIV and AIDS 2021. PMID: 33186229


  59. Hickey MD, Sergi F, Zhang K, Spinelli MA, Black D, Sola C, Blaz V, Nguyen JQ, Oskarsson J, Gandhi M, Havlir DV. Pragmatic randomized trial of a pre-visit intervention to improve the quality of telemedicine visits for vulnerable patients living with HIV. Journal of telemedicine and telecare 2020. PMID: 33342328


  60. Spinelli MA, Hickey MD, Glidden DV, Nguyen JQ, Oskarsson JJ, Havlir D, Gandhi M. Viral suppression rates in a safety-net HIV clinic in San Francisco destabilized during COVID-19. AIDS (London, England) 2020. PMID: 32910069


  61. Laborde ND, Kinley PM, Spinelli M, Vittinghoff E, Whitacre R, Scott HM, Buchbinder SP. Understanding PrEP Persistence: Provider and Patient Perspectives. Volume 24 of Issue 9. AIDS and behavior 2020. PMID: 32048078


  62. Spinelli MA, Haberer JE, Chai PR, Castillo-Mancilla J, Anderson PL, Gandhi M. Approaches to Objectively Measure Antiretroviral Medication Adherence and Drive Adherence Interventions. Current HIV/AIDS reports 2020. PMID: 32424549


  63. Spinelli MA, Laborde N, Kinley P, Whitacre R, Scott HM, Walker N, Liu AY, Gandhi M, Buchbinder SP. The importance of PrEP persistence in preventing HIV infections on PrEP. Journal of the International AIDS Society 2020. PMID: 32844591


  64. Spinelli MA, Buchbinder SP. Pre-exposure Prophylaxis Persistence Is a Critical Issue in PrEP Implementation. Volume 71 of Issue 3. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2020. PMID: 31509603


  65. Stalter RM, Baeten JM, Donnell D, Spinelli MA, Glidden DV, Rodrigues WC, Wang G, Vincent M, Mugo N, Mujugira A, Marzinke M, Hendrix C, Gandhi M. Urine Tenofovir Levels Measured by a Novel Immunoassay Predict HIV Protection. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2020. PMID: 32569370


  66. Spinelli MA, Rodrigues WC, Wang G, Vincent M, Glidden DV, Okochi H, Stalter R, Defechereux P, Deutsch M, Grant RM, Ngure K, Mugo NR, Baeten JM, Gandhi M. HIGH ACCURACY OF A REAL-TIME URINE ANTIBODY-BASED TENOFOVIR POINT-OF-CARE TEST COMPARED TO LABORATORY-BASED ELISA IN DIVERSE POPULATIONS. Journal of acquired immune deficiency syndromes (1999) 2020. PMID: 32167963


  67. Drain P, Ngure K, Mugo N, Spinelli M, Chatterjee P, Bacchetti P, Glidden D, Baeten J, Gandhi M. Testing a Real-Time Tenofovir Urine Adherence Assay for Monitoring and Providing Feedback to Preexposure Prophylaxis in Kenya (PUMA): Protocol for a Pilot Randomized Controlled Trial. JMIR research protocols 2020. PMID: 32238341


  68. Spinelli MA, Laborde N, Kinley P, Whitacre R, Scott HM, Walker N, Liu AY, Gandhi M, Buchbinder SP. Missed opportunities to prevent HIV infections among pre-exposure prophylaxis users: a population-based mixed methods study, San Francisco, United States. Journal of the International AIDS Society 2020. PMID: 32294338


  69. Gandhi M, Wang G, King R, Rodrigues WC, Vincent M, Glidden DV, Cressey TR, Bacchetti P, Spinellii MA, Okochi H, Siriprakaisil O, Klinbuayaem V, Mugo NR, Ngure K, Drain PK, Baeten JM. Development and Validation of the First Point-of-Care Assay to Objectively Monitor Adherence to HIV Treatment and Prevention in Real-Time in Routine Settings. AIDS (London, England) 2019. PMID: 31634188


  70. Scott HM, Spinelli M, Vittinghoff E, Morehead-Gee A, Hirozawa A, James C, Hammer H, Liu A, Gandhi M, Buchbinder S. Racial/Ethnic and HIV risk category disparities in PrEP discontinuation among patients in publicly-funded primary care clinics. AIDS (London, England) 2019. PMID: 31436610


  71. Spinelli MA, Hessol NA, Schwarcz S, Hsu L, Parisi MK, Pipkin S, Scheer S, Havlir D, Buchbinder SP. Homelessness at diagnosis is associated with death among people with HIV in a population-based study of a U.S. City. AIDS (London, England) 2019. PMID: 31259765


  72. Spinelli MA, Glidden DV, Anderson PL, Gandhi M, McMahan VM, Defechereux P, Schechter M, Veloso VG, Chariyalertsak S, Guanira JV, Bekker LG, Buchbinder S, Grant RM. Impact of Estimated PrEP Adherence Patterns on Bone Mineral Density in a Large PrEP Demonstration Project. AIDS research and human retroviruses 2019. PMID: 31119944


  73. Paul Drain, Kenneth Ngure, Nelly Mugo, Matthew Spinelli, Purba Chatterjee, Peter Bacchetti, David Glidden, Jared Baeten, Monica Gandhi. Testing a Real-Time Tenofovir Urine Adherence Assay for Monitoring and Providing Feedback to PrEP in Kenya (the PUMA study): A Pilot Randomized Clinical Trial (Preprint). JMIR research protocols 2019. PMID:


  74. Spinelli MA, Glidden DV, Anderson PL, Gandhi M, Cohen S, Vittinghoff E, Coleman ME, Scott H, Bacon O, Elion R, Kolber MA, Buchbinder SP, Liu AY. Brief Report: Short-Term Adherence Marker to PrEP Predicts Future Nonretention in a Large PrEP Demo Project: Implications for Point-of-Care Adherence Testing. Journal of acquired immune deficiency syndromes (1999) 2019. PMID: 31095005


  75. Gandhi M, Bacchetti P, SpinelliI MA, Okochi H, Baeten JM, Siriprakaisil O, Klinbuayaem V, Rodrigues WC, Wang G, Vincent M, Cressey TR, Drain PK. Validation of a Urine Tenofovir Immunoassay for Adherence Monitoring to PrEP and ART and Establishing the Cut-Off for a Point-of-Care Test. Journal of acquired immune deficiency syndromes (1999) 2019. PMID: 30664078


  76. Gandhi M, Spinelli MA, Mayer KH. Addressing the Sexually Transmitted Infection and HIV Syndemic. JAMA 2019. PMID: 30964514


  77. Spinelli MA, Scott HM, Vittinghoff E, Liu AY, Coleman K, Buchbinder SP. High Interest in Doxycycline for Sexually Transmitted Infection Postexposure Prophylaxis in a Multicity Survey of Men Who Have Sex With Men Using a Social Networking Application. Volume 46 of Issue 4. Sexually transmitted diseases 2019. PMID: 30870327


  78. Spinelli MA, Glidden DV, Rodrigues WC, Wang G, Vincent M, Okochi H, Kuncze K, Mehrotra M, Defechereux P, Buchbinder SP, Grant RM, Gandhi M. Low tenofovir level in urine by a novel immunoassay is associated with seroconversion in a preexposure prophylaxis demonstration project. AIDS (London, England) 2019. PMID: 30649051


  79. Spinelli MA, Scott HM, Vittinghoff E, Liu AY, Gonzalez R, Morehead-Gee A, Gandhi M, Buchbinder SP. Missed Visits Associated With Future Preexposure Prophylaxis (PrEP) Discontinuation Among PrEP Users in a Municipal Primary Care Health Network. Open forum infectious diseases 2019. PMID: 30949540


  80. Matthew A Spinelli, Hyman Scott, Eric Vittinghoff, Albert Y Liu, Kenneth Coleman, Monica Gandhi, Susan P Buchbinder. 2272. High Interest in Doxycycline for Sexually Transmitted Infection Post-Exposure Prophylaxis (Doxy-PEP) in a Multi-city Survey of Men Having Sex With Men (MSM) Using a Social-Networking App. Open forum infectious diseases 2018. PMID:


  81. Spinelli MA, Scott HM, Vittinghoff E, Liu AY, Morehead-Gee A, Gonzalez R, Gandhi M, Buchbinder SP. Brief Report: A Panel Management and Patient Navigation Intervention Is Associated With Earlier PrEP Initiation in a Safety-Net Primary Care Health System. Journal of acquired immune deficiency syndromes (1999) 2018. PMID: 30085955


  82. Gandhi M, Bacchetti P, Rodrigues WC, Spinelli M, Koss CA, Drain PK, Baeten JM, Mugo NR, Ngure K, Benet LZ, Okochi H, Wang G, Vincent M. Development and Validation of an Immunoassay for Tenofovir in Urine as a Real-Time Metric of Antiretroviral Adherence. EClinicalMedicine 2018. PMID: 30906930


  83. Spinelli MA, Scott HM, Vittinghoff E, Liu AY, Morehead-Gee A, Gonzalez R, Buchbinder SP. Provider Adherence to Pre-exposure Prophylaxis Monitoring Guidelines in a Large Primary Care Network. Volume 5 of Issue 6. Open forum infectious diseases 2018. PMID: 29977959


  84. Spinelli MA, Frongillo EA, Sheira LA, Palar K, Tien PC, Wilson T, Merenstein D, Cohen M, Adedimeji A, Wentz E, Adimora AA, Metsch LR, Turan JM, Kushel MB, Weiser SD. Food Insecurity is Associated with Poor HIV Outcomes Among Women in the United States. Volume 21 of Issue 12. AIDS and behavior 2017. PMID: 29119474


  85. Spinelli MA, Ponath C, Tieu L, Hurstak EE, Guzman D, Kushel M. Factors associated with substance use in older homeless adults: Results from the HOPE HOME study. Volume 38 of Issue 1. Substance abuse 2016. PMID: 27897965


  86. Papadopulos F, Spinelli M, Valente S, Foroni L, Orrico C, Alviano F, Pasquinelli G. Common tasks in microscopic and ultrastructural image analysis using ImageJ. Volume 31 of Issue 6. Ultrastructural pathology 2007. PMID: 18098058


  87. Chen P, Hübner W, Spinelli MA, Chen BK. Predominant mode of human immunodeficiency virus transfer between T cells is mediated by sustained Env-dependent neutralization-resistant virological synapses. Volume 81 of Issue 22. Journal of virology 2007. PMID: 17728240