Liviu Klein, MD, MS

Guglin M, Munshi K, Volz E, Bennett M, Benjamin TA, Bhatt K, Bhimaraj A, Fendler T, Fudim M, Guha A, Heywood JT, Jonsson O, Klein L, McCann P, Muse E, Robinson M, Sauer A, Shah H, Abraham J. Misclassification of Pulmonary Hypertension with Current Hemodynamic Criteria. Chest 2024. PMID: 39209062

Guichard JL, Bonno EL, Nassif ME, Khumri TM, Miranda D, Jonsson O, Shah H, Alexy T, Macaluso GP, Sur J, Hickey G, McCann P, Cowger JA, Badiye A, Old WD, Raza Y, Masha L, Kunavarapu CR, Bennett M, Sharif F, Kiernan M, Mullens W, Chaparro SV, Mahr C, Amin RR, Stevenson LW, Hiivala NJ, Owens MM, Sauerland A, Forouzan O, Klein L. Seated Pulmonary Artery Pressure Monitoring in Patients With Heart Failure: Results of the PROACTIVE-HF Trial. JACC. Heart failure 2024. PMID: 39152983

Urey MA, Hibbert B, Jorde U, Eckman P, Simard T, Labinaz M, Nazer B, Wiley M, Gupta B, Sauer A, Shah H, Sorajja P, Pineda AM, Missov E, Mahmud E, Kahwash R, Lilly S, Latib A, Murthy S, Fam N, Garcia S, Chung ES, Klein L, Cheng R, Houston BA, Amoroso NS, Chang L, Gafoor S, Chaudhry SP, Hermiller J, Schwartz JG, Aldaia L, Koulogiannis K, Gray WA, Zahr F. Left atrial to coronary sinus shunting for treatment of heart failure with mildly reduced or preserved ejection fraction: The ALT FLOW Early Feasibility Study 1-year results. European journal of heart failure 2024. PMID: 38606485

Cowger JA, Basir MB, Baran DA, Hayward CS, Rangaswami J, Walton A, Tita C, Minear S, Hakemi E, Klein L, Cheng R, Wu R, Mohanty BD, Heuring JJ, Neely E, Shah P, Aortix CRS Pilot Study Investigators. Safety and Performance of the Aortix Device in Acute Decompensated Heart Failure and Cardiorenal Syndrome. JACC. Heart failure 2023. PMID: 37804307

Trachtenberg B, Jennings D, Grafton G, Loyaga-Rendon R, Cogswell R, Klein L, Shah P, Kiernan M, Vorovich E, Cowger J. Corrigendum to "HFSA Expert Consensus Statement on the Medical Management of Patients on Durable Mechanical Circulatory Support": Journal of Cardiac Failure Vol. 29 No. 4, pp. 479-502. Journal of cardiac failure 2023. PMID: 37414594

Fiedler AG, Klein L, DeMarco T, Kouretas P, Smith JW. Comment on: Detection and Management of HLA Sensitization in Candidates for Adult Heart Transplantation. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2023. PMID: 37088342

Hahn EA, Allen LA, Lee CS, Denfeld QE, Stehlik J, Cella D, Lindenfeld J, Teuteberg JJ, McIlvennan CK, Kiernan MS, Beiser DG, Walsh MN, Adler ED, Ruo B, Kirklin JK, Klein L, Bedjeti K, Cummings PD, Burns JL, Vela AM, Grady KL. PROMIS� Physical, Mental and Social Health Outcomes Improve from Before to Early After LVAD Implant: Findings from the Mechanical Circulatory Support: Measures of Adjustment and Quality of Life (MCS A-QOL) Study. Journal of cardiac failure 2023. PMID: 37004864

Trachtenberg B, Cowger J, Jennings DL, Grafton G, Loyaga-Rendon R, Cogswell R, Klein L, Shah P, Kiernan M, Vorovich E. HFSA Expert Consensus Statement on the Medical Management of Patients on Durable Mechanical Circulatory Support. Journal of cardiac failure 2023. PMID: 36828256

Hahn EA, Walsh MN, Allen LA, Lee CS, Denfeld QE, Teuteberg JJ, Beiser DG, McIlvennan CK, Lindenfeld J, Klein L, Adler ED, Stehlik J, Ruo B, Bedjeti K, Cummings PD, Vela AM, Grady KL. Validity of Patient-Reported Outcomes Measurement Information System Physical, Mental, and Social Health Measures After Left Ventricular Assist Device Implantation and Implications for Patient Care. Circulation. Cardiovascular quality and outcomes 2023. PMID: 36752104

Aras MA, Abreau S, Mills H, Radhakrishnan L, Klein L, Mantri N, Rubin B, Barrios J, Chehoud C, Kogan E, Gitton X, Nnewihe A, Quinn D, Bridges C, Butte AJ, Olgin JE, Tison GH. Electrocardiogram Detection of Pulmonary Hypertension Using Deep Learning. Journal of cardiac failure 2023. PMID: 36706977

Guichard JL, Cowger JA, Chaparro SV, Kiernan MS, Mullens W, Mahr C, Mullin C, Forouzan O, Hiivala NJ, Sauerland A, Leadley K, Klein L, Greenville, South Carolina; Detroit, Michigan; Miami, Florida; Boston, Massachusetts; Genk, Belgium;. Rationale and Design of the Proactive-HF Trial for Managing Patients With NYHA Class III Heart Failure by Using the Combined Cordella Pulmonary Artery Sensor and the Cordella Heart Failure System. Journal of cardiac failure 2022. PMID: 36191758

Fudim M, Shahid I, Emani S, Klein L, Dupuy-McCauley KL, Zieroth S, Mentz RJ. Evaluation and Treatment of Central Sleep Apnea in Patients with Heart Failure. Current problems in cardiology 2022. PMID: 35995244

Shandhi MMH, Fan J, Heller J, Etemadi M, Klein L, Inan O. Estimation of Changes in Intracardiac Hemodynamics Using Wearable Seismocardiography and Machine Learning in Patients with Heart Failure: A Feasibility Study. 2022. PMID: 35100106

Fudim M, Fail PS, Litwin SE, Shaburishvili T, Goyal P, Hummel SL, Borlaug BA, Mohan RC, Patel RB, Mitter SS, Klein L, Rocha-Singh K, Patel MR, Reddy VY, Burkhoff D, Shah SJ. Endovascular ablation of the right greater splanchnic nerve in heart failure with preserved ejection fraction: early results of the REBALANCE-HF trial roll-in cohort. 2022. PMID: 35598154

Jering KS, Campagnari C, Claggett B, Adler E, Klein L, Ahmad FS, Voors AA, Solomon S, Yagil A, Greenberg B. Improving Clinical Trial Efficiency Using a Machine Learning Based Risk Score to Enrich Study Populations. 2022. PMID: 35508918

Haring B, Hunt RP, Manson JE, LaMonte MJ, Klein L, Allison MA, Wild RA, Wallace RB, Shadyab AH, Breathett K, Eaton C, Wassertheil-Smoller S, Shimbo D. Blood Pressure Variability and Heart Failure Hospitalization: Results From the Women's Health Initiative. 2022. PMID: 35525685

Hayward C, Adachi I, Baudart S, Davis E, Feller ED, Kinugawa K, Klein L, Li S, Lorts A, Mahr C, Mathew J, Morshuis M, Müller M, Ono M, Pagani FD, Pappalardo F, Rich J, Robson D, Rosenthal DN, Saeed D, Salerno C, Sauer AJ, Schlöglhofer T, Tops L, VanderPluym C. Global best practices consensus: Long-term management of patients with hybrid centrifugal flow left ventricular assist device support. 2022. PMID: 35624053

Hernandez AF, Albert NM, Allen LA, Ahmed R, Averina V, Boehmer JP, Cowie MR, Chien CV, Galvao M, Klein L, Kwan B, Lam CSP, Ruble SB, Stolen CM, Stein K, MANAGE-HF Study. Multiple cArdiac seNsors for mAnaGEment of Heart Failure (MANAGE-HF) - Phase I Evaluation of the Integration and Safety of the HeartLogic Multisensor Algorithm in Patients With Heart Failure. 2022. PMID: 35460884

Neill L, Etemadi M, Klein L, Inan OT. Novel Noninvasive Biosensors and Artificial Intelligence for Optimized Heart Failure Management. 2022. PMID: 35411315

Banerjee R, Lo M, Klein L, Aras M, Logan AC. Anthracyclines in a patient with acute leukemia and severe cardiomyopathy requiring mechanical support: A case report. 2021. PMID: 34846217

Klein L. Is There a Logic in Using Device-Based Algorithms to Prevent Heart Failure Decompensations? 2021. PMID: 34634918

Kalantarian S, Åström Aneq M, Svetlichnaya J, Sharma S, Vittinghoff E, Klein L, Scheinman MM. Long-Term Electrocardiographic and Echocardiographic Progression of Arrhythmogenic Right Ventricular Cardiomyopathy and Their Correlation With Ventricular Tachyarrhythmias. 2021. PMID: 34550004

Darden D, Ammirati E, Brambatti M, Lin A, Hsu JC, Shah P, Perna E, Cikes M, Gjesdal G, Potena L, Masetti M, Jakus N, Van De Heyning C, De Bock D, Brugts JJ, Russo CF, Veenis JF, Rega F, Cipriani M, Frigerio M, Liviu K, Hong KN, Adler E, Braun OÖ. Cardiovascular implantable electronic device therapy in patients with left ventricular assist devices: insights from TRAViATA. 2021. PMID: 34437934

Tison GH, Avram R, Nah G, Klein L, Howard BV, Allison MA, Casanova R, Blair RH, Breathett K, Foraker RE, Olgin JE, Parikh NI. Predicting incident heart failure in women with machine learning: The Women's Health Initiative Cohort. The Canadian journal of cardiology 2021. PMID: 34400272

Quesada O, Shandhi MMH, Beach S, Dowling S, Tandon D, Heller J, Etemadi M, Roy S, Gonzalez Velez JM, Inan OT, Klein L. Use of Ballistocardiography to Monitor Cardiovascular Hemodynamics in Preeclampsia. Women's health reports (New Rochelle, N.Y.) 2021. PMID: 33937907

Wieselthaler GM, Klein L, Cheung AW, Danter MR, Strueber M, Mahr C, Mokadam NA, Maltais S, McGee EC. Two-Year Follow Up of the LATERAL Clinical Trial: A Focus on Adverse Events. Circulation. Heart failure 2021. PMID: 33866829

Kalantarian S, Vittinghoff E, Klein L, Scheinman MM. Effect of preload reducing therapy on right ventricular size and function in patients with arrhythmogenic right ventricular cardiomyopathy. Heart rhythm 2021. PMID: 33722762

LaMonte MJ, Larson JC, Manson JE, Bellettiere J, Lewis CE, LaCroix AZ, Bea JW, Johnson KC, Klein L, Noel CA, Stefanick ML, Wactawski-Wende J, Eaton CB. Association of Sedentary Time and Incident Heart Failure Hospitalization in Postmenopausal Women. Circulation. Heart failure 2020. PMID: 33228398

Breathett K, Kohler LN, Eaton CB, Franceschini N, Garcia L, Klein L, Martin LW, Ochs-Balcom HM, Shadyab AH, Cené CW. When the At-Risk Do Not Develop Heart Failure: Understanding Positive Deviance Among Postmenopausal African-American and Hispanic Women. Journal of cardiac failure 2020. PMID: 33232822

Lam PH, Barac A, Nohria A, Reding KW, Najjar SS, Fonarow GC, Pan K, Sheriff H, Morgan CJ, Chlebowski RT, Klein L, Eaton CB, Howard BV, Ahmed A, Mohammed SF. Temporal Associations and Outcomes of Breast Cancer and Heart Failure in Postmenopausal Women. JACC. CardioOncology 2020. PMID: 34396268

Ammirati E, Brambatti M, Braun OÖ, Shah P, Cipriani M, Bui QM, Veenis J, Lee E, Xu R, Hong KN, Van de Heyning CM, Perna E, Timmermans P, Cikes M, Brugts JJ, Veronese G, Minto J, Smith S, Gjesdal G, Gernhofer YK, Partida C, Potena L, Masetti M, Boschi S, Loforte A, Jakus N, Milicic D, Nilsson J, De Bock D, Sterken C, Van den Bossche K, Rega F, Tran H, Singh R, Montomoli J, Mondino M, Greenberg B, Russo CF, Pretorius V, Liviu K, Frigerio M, Adler ED. Outcome of patients on heart transplant list treated with a continuous-flow left ventricular assist device: Insights from the TRans-Atlantic registry on VAd and TrAnsplant (TRAViATA). International journal of cardiology 2020. PMID: 32950592

Hasan Shandhi MM, Aras M, Wynn S, Fan J, Heller JA, Etemadi M, Klein L, Inan OT. Cardiac Function Monitoring for Patients Undergoing Cancer Treatments Using Wearable Seismocardiography: A Proof-of-Concept Study. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 2020. PMID: 33018894

Shandhi MMH, Hersek S, Fan J, Sander E, Marco T, Heller JA, Etemadi M, Klein L, Inan OT. Wearable Patch Based Estimation of Oxygen Uptake and Assessment of Clinical Status during Cardiopulmonary Exercise Testing in Patients with Heart Failure. Journal of cardiac failure 2020. PMID: 32473379

Semiz B, Inan O, Hersek S, Pouyan MB, Partida C, Arroyo LB, Selby V, Wieselthaler G, Rehg J, Klein L. Detecting Suspected Pump Thrombosis in Left Ventricular Assist Devices via Acoustic Analysis. IEEE journal of biomedical and health informatics 2020. PMID: 31940570

Stern LK, Selby VN, Kolaitis NA, Boin F, Aras M, Klein L, De Marco T. Heart-lung transplantation: A viable option for connective tissue diseases. Clinical transplantation 2019. PMID: 31867763

Adler ED, Voors AA, Klein L, Macheret F, Braun OO, Urey MA, Zhu W, Sama I, Tadel M, Campagnari C, Greenberg B, Yagil A. Improving risk prediction in heart failure using machine learning. European journal of heart failure 2019. PMID: 31721391

Liu L, Klein L, Eaton C, Panjrath G, Martin LW, Chae CU, Greenland P, Lloyd-Jones DM, Wactawski-Wende J, Manson JE. Menopausal Hormone Therapy and Risks of First Hospitalized Heart Failure and Its Subtypes During the Intervention and Extended Postintervention Follow-up of the Women's Health Initiative Randomized Trials. Journal of cardiac failure 2019. PMID: 31536806

Rosenthal DG, Parwani P, Murray TO, Petek BJ, Benn BS, De Marco T, Gerstenfeld EP, Janmohamed M, Klein L, Lee BK, Moss JD, Scheinman MM, Hsia HH, Selby V, Koth LL, Pampaloni MH, Zikherman J, Vedantham V. Long-Term Corticosteroid-Sparing Immunosuppression for Cardiac Sarcoidosis. Journal of the American Heart Association 2019. PMID: 31538835

Aydemir VB, Nagesh S, Shandhi M, Fan J, Klein L, Etemadi M, Heller JA, Inan O, Rehg JM. Classification of Decompensated Heart Failure from Clinical and Home Ballistocardiography. IEEE transactions on bio-medical engineering 2019. PMID: 31425011

Abraham J, McCann P, Wang L, Schnell Heringer A, Paulsen J, Chappell J, Remick J, Westerdahl D, Lewis R, Callis K, Spinelli KJ, Klein L. Internal Jugular Vein as Alternative Access for Implantation of a Wireless Pulmonary Artery Pressure Sensor. Circulation. Heart failure 2019. PMID: 31525097

Cardona-Guarache R, Åström-Aneq M, Oesterle A, Asirvatham R, Svetlichnaya J, Marcus GM, Gerstenfeld EP, Klein L, Scheinman MM. Atrial arrhythmias in patients with arrhythmogenic right ventricular cardiomyopathy: Prevalence, echocardiographic predictors, and treatment. Journal of cardiovascular electrophysiology 2019. PMID: 31310380

DesJardin JT, Manicardi M, Svetlichnaya Y, Kolaitis NA, Papolos AI, Selby VN, Zier LS, Klein L, Aras MA, Yao FY, Roberts JP, De Marco T. Non-Invasive Estimation of Pulmonary Vascular Resistance Improves Portopulmonary Hypertension Screening in Liver Transplant Candidates. Clinical transplantation 2019. PMID: 31074522

McGee E, Danter M, Strueber M, Mahr C, Mokadam NA, Wieselthaler G, Klein L, Lee S, Boeve T, Maltais S, Pretorius GV, Adler E, Vassiliades T, Cheung A. Evaluation of a lateral thoracotomy implant approach for a centrifugal-flow left ventricular assist device: The LATERAL clinical trial. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2019. PMID: 30945636

Arnaout R, Nah G, Marcus G, Tseng Z, Foster E, Harris IS, Divanji P, Klein L, Gonzalez J, Parikh N. Pregnancy complications and premature cardiovascular events among 1.6 million California pregnancies. Open heart 2019. PMID: 30997125

Moss JD, Oesterle A, Raiman M, Flatley EE, Beaser AD, Jeevanandam V, Klein L, Ota T, Wieselthaler G, Uriel N, Tung R. Feasibility and utility of intraoperative epicardial scar characterization during left ventricular assist device implantation. Journal of cardiovascular electrophysiology 2018. PMID: 30516301

LaMonte MJ, Manson JE, Chomistek AK, Larson JC, Lewis CE, Bea JW, Johnson KC, Li W, Klein L, LaCroix AZ, Stefanick ML, Wactawski-Wende J, Eaton CB. Physical Activity and Incidence of Heart Failure in Postmenopausal Women. JACC. Heart failure 2018. PMID: 30196073

Breathett K, Leng I, Foraker RE, Abraham WT, Coker L, Whitfield KE, Shumaker S, Manson JE, Eaton CB, Howard BV, Ijioma N, Cené CW, Martin LW, Johnson KC, Klein L. Risk Factor Burden, Heart Failure, and Survival in Women of Different Ethnic Groups: Insights From the Women's Health Initiative. Circulation. Heart failure 2018. PMID: 29716899

Pandey A, Omar W, Ayers C, LaMonte M, Klein L, Allen NB, Kuller LH, Greenland P, Eaton CB, Gottdiener JS, Lloyd-Jones DM, Berry JD. Sex and Race Differences in Lifetime Risk of Heart Failure With Preserved Ejection Fraction and Heart Failure With Reduced Ejection Fraction. Circulation 2018. PMID: 29352072

Inan OT, Baran Pouyan M, Javaid AQ, Dowling S, Etemadi M, Dorier A, Heller JA, Bicen AO, Roy S, De Marco T, Klein L. Novel Wearable Seismocardiography and Machine Learning Algorithms Can Assess Clinical Status of Heart Failure Patients. Circulation. Heart failure 2018. PMID: 29330154

Klein L. (Re)Discovering the Neurohormonal and Hemodynamic Duality of Heart Failure. Journal of the American College of Cardiology 2017. PMID: 28982502

Hall PS, Nah G, Howard BV, Lewis CE, Allison MA, Sarto GE, Waring ME, Jacobson LT, Manson JE, Klein L, Parikh NI. Reproductive Factors and Incidence of Heart Failure Hospitalization in the Women's Health Initiative. Journal of the American College of Cardiology 2017. PMID: 28521890

Pandey A, LaMonte M, Klein L, Ayers C, Psaty BM, Eaton CB, Allen NB, de Lemos JA, Carnethon M, Greenland P, Berry JD. Relationship Between Physical Activity, Body Mass Index, and Risk of Heart Failure. Journal of the American College of Cardiology 2017. PMID: 28254175

Brondfield MN, Reid MJ, Rutishauser RL, Cope JR, Tang J, Ritter JM, Matanock A, Ali I, Doernberg SB, Hilts-Horeczko A, DeMarco T, Klein L, Babik JM. Disseminated Acanthamoeba infection in a heart transplant recipient treated successfully with a miltefosine-containing regimen: Case report and review of the literature. Volume 19 of Issue 2. Transplant infectious disease : an official journal of the Transplantation Society 2017. PMID: 28067969

Cowie MR, Simon M, Klein L, Thokala P. The cost-effectiveness of real-time pulmonary artery pressure monitoring in heart failure patients: a European perspective. European journal of heart failure 2017. PMID: 28176424

Eaton CB, Pettinger M, Rossouw J, Martin LW, Foraker R, Quddus A, Liu S, Wampler NS, Hank Wu WC, Manson JE, Margolis K, Johnson KC, Allison M, Corbie-Smith G, Rosamond W, Breathett K, Klein L. Risk Factors for Incident Hospitalized Heart Failure With Preserved Versus Reduced Ejection Fraction in a Multiracial Cohort of Postmenopausal Women. Circulation. Heart failure 2016. PMID: 27682440

Sack KL, Baillargeon B, Acevedo-Bolton G, Genet M, Rebelo N, Kuhl E, Klein L, Weiselthaler GM, Burkhoff D, Franz T, Guccione JM. Partial LVAD restores ventricular outputs and normalizes LV but not RV stress distributions in the acutely failing heart in silico. The International journal of artificial organs 2016. PMID: 27646633

Klein L. Treating Hemodynamic Congestion Is the Key to Prevent Heart Failure Hospitalizations. JACC. Heart failure 2016. PMID: 27126282

Klein L, Greenberg BH, Konstam MA, Gregory D, Kociol RD, Johnson MR, de Marco T. Activities and Compensation of Advanced Heart Failure Specialists: Results of the Heart Failure Society of America (HFSA) Survey. Journal of cardiac failure 2015. PMID: 26362520

Rogers SE, Klein L, Perissinotto CM. The importance of cognitive assessment before ventricular device placement: a teachable moment. JAMA internal medicine 2015. PMID: 25822770

Etemadi M, Inan OT, Heller JA, Hersek S, Klein L, Roy S. A Wearable Patch to Enable Long-Term Monitoring of Environmental, Activity and Hemodynamics Variables. IEEE transactions on biomedical circuits and systems 2015. PMID: 25974943

Donneyong MM, Hornung CA, Taylor KC, Baumgartner RN, Myers JA, Eaton CB, Gorodeski EZ, Klein L, Martin LW, Shikany JM, Song Y, Li W, Manson JE. Risk of heart failure among postmenopausal women: a secondary analysis of the randomized trial of vitamin D plus calcium of the women's health initiative. Circulation. Heart failure 2014. PMID: 25398967

Wiens AD, Etemadi M, Roy S, Klein L, Inan OT. Toward continuous, noninvasive assessment of ventricular function and hemodynamics: wearable ballistocardiography. IEEE journal of biomedical and health informatics 2014. PMID: 25265619

Klein L, Hsia H. Sudden cardiac death in heart failure. Cardiology clinics 2014. PMID: 24286584

Etemadi M, Hersek S, Tseng JM, Rabbani N, Heller JA, Roy S, Klein L, Inan OT. Tracking clinical status for heart failure patients using ballistocardiography and electrocardiography signal features. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 2014. PMID: 25571162

Wiens A, Etemadi M, Klein L, Roy S, Inan OT. Wearable ballistocardiography: preliminary methods for mapping surface vibration measurements to whole body forces. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 2014. PMID: 25571158

Sridharan L, Klein L. Prognostic factors in patients hospitalized for heart failure. Current heart failure reports 2013. PMID: 24122287

Perez MV, Wang PJ, Larson JC, Soliman EZ, Limacher M, Rodriguez B, Klein L, Manson JE, Martin LW, Prineas R, Connelly S, Hlatky M, Wassertheil-Smoller S, Stefanick ML. Risk factors for atrial fibrillation and their population burden in postmenopausal women: the Women's Health Initiative Observational Study. Heart (British Cardiac Society) 2013. PMID: 23756655

Perez MV, Wang PJ, Larson JC, Virnig BA, Cochrane B, Curb JD, Klein L, Manson JE, Martin LW, Robinson J, Wassertheil-Smoller S, Stefanick ML. Effects of postmenopausal hormone therapy on incident atrial fibrillation: the Women's Health Initiative randomized controlled trials. Circulation. Arrhythmia and electrophysiology 2012. PMID: 23169946

Klein L. ACP Journal Club. Review: new oral anticoagulants reduced stroke and systemic embolism compared with warfarin in AF. Annals of internal medicine 2012. PMID: 22986394

Avery CL, Sethupathy P, Buyske S, He Q, Lin DY, Arking DE, Carty CL, Duggan D, Fesinmeyer MD, Hindorff LA, Jeff JM, Klein L, Patton KK, Peters U, Shohet RV, Sotoodehnia N, Young AM, Kooperberg C, Haiman CA, Mohlke KL, Whitsel EA, North KE. Fine-mapping and initial characterization of QT interval loci in African Americans. PLoS genetics 2012. PMID: 22912591

Eaton CB, Abdulbaki AM, Margolis KL, Manson JE, Limacher M, Klein L, Allison MA, Robinson JG, Curb JD, Martin LA, Liu S, Howard BV. Racial and ethnic differences in incident hospitalized heart failure in postmenopausal women: the Women's Health Initiative. Circulation 2012. PMID: 22753306

Klein L. Apixaban reduced stroke and systemic embolism compared with warfarin in atrial fibrillation. Annals of internal medicine 2012. PMID: 22250164

Klein L. Rivaroxaban reduced stroke and systemic embolism compared with warfarin in nonvalvular AF. Annals of internal medicine 2012. PMID: 22250165

Shah RU, Winkleby MA, Van Horn L, Phillips LS, Eaton CB, Martin LW, Rosal MC, Manson JE, Ning H, Lloyd-Jones DM, Klein L. Education, income, and incident heart failure in post-menopausal women: the Women's Health Initiative Hormone Therapy Trials. Journal of the American College of Cardiology 2011. PMID: 21939829

Klein L, Grau-Sepulveda MV, Bonow RO, Hernandez AF, Williams MV, Bhatt DL, Fonarow GC. Quality of care and outcomes in women hospitalized for heart failure. Circulation. Heart failure 2011. PMID: 21862732

Klein L. Omnes viae Romam ducunt: Asymptomatic cardiac and noncardiac organ system dysfunction leads to heart failure. Circulation 2011. PMID: 21730317

Svetlichnaya J, Klein L. Atrial fibrillation in elderly patients with heart failure: convergence of two cardiovascular epidemics in the 21st Century. Expert review of cardiovascular therapy 2011. PMID: 21809972

Tempelhof MW, Klein L, Cotts WG, Benzuly KH, Davidson CJ, Meyers SN, McCarthy PM, Malaisrie CS, McGee EC, Beohar N. Clinical experience and patient outcomes associated with the TandemHeart percutaneous transseptal assist device among a heterogeneous patient population. ASAIO journal (American Society for Artificial Internal Organs : 1992) 2011. PMID: 21546824

Shah RU, Tsai V, Klein L, Heidenreich PA. Characteristics and outcomes of very elderly patients after first hospitalization for heart failure. Circulation. Heart failure 2011. PMID: 21467294

Klein L. ACP Journal Club. Higher-dose dabigatran reduced stroke, but not major hemorrhage, more than warfarin in atrial fibrillation. Annals of internal medicine 2010. PMID: 20083817

Shah RU, Klein L, Lloyd-Jones DM. Heart failure in women: epidemiology, biology and treatment. Women's health (London, England) 2009. PMID: 19702451

Klein L, Massie BM, Leimberger JD, O'Connor CM, Piña IL, Adams KF, Califf RM, Gheorghiade M. Admission or changes in renal function during hospitalization for worsening heart failure predict postdischarge survival: results from the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CHF). Circulation. Heart failure 2008. PMID: 19808267

Klein L, O'connell JB. Thromboembolic risk in the patient with heart failure. Current treatment options in cardiovascular medicine 2007. PMID: 17761116

Lloyd-Jones DM, Liu K, Colangelo LA, Yan LL, Klein L, Loria CM, Lewis CE, Savage P. Consistently stable or decreased body mass index in young adulthood and longitudinal changes in metabolic syndrome components: the Coronary Artery Risk Development in Young Adults Study. Circulation 2007. PMID: 17283263

Gheorghiade M, Zannad F, Sopko G, Klein L, Piña IL, Konstam MA, Massie BM, Roland E, Targum S, Collins SP, Filippatos G, Tavazzi L. Acute heart failure syndromes: current state and framework for future research. Circulation 2005. PMID: 16365214

De Luca L, Klein L, Udelson JE, Orlandi C, Sardella G, Fedele F, Gheorghiade M. Hyponatremia in patients with heart failure. The American journal of cardiology 2005. PMID: 16399089

Klein L, O'Connor CM, Leimberger JD, Gattis-Stough W, Piña IL, Felker GM, Adams KF, Califf RM, Gheorghiade M. Lower serum sodium is associated with increased short-term mortality in hospitalized patients with worsening heart failure: results from the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CHF) s Circulation 2005. PMID: 15867182

Klein L. Posting treatment recommendations to primary care physicians does not improve care for people with myocardial infarction or heart failure. Commentary. Evidence-based cardiovascular medicine 2005. PMID: 16379994

Klein L, Gheorghiade M. Coronary artery disease and prevention of heart failure. The Medical clinics of North America 2004. PMID: 15331314

Danciu SC, Klein L, Hosseini MM, Ibrahim L, Coyle BW, Kehoe RF. A predictive model for survival after in-hospital cardiopulmonary arrest. Resuscitation 2004. PMID: 15246581

Klein L, Galvez A, Klein O, Chediak J. Warfarin-induced limb gangrene in the setting of lung adenocarcinoma. American journal of hematology 2004. PMID: 15164386

Klein L, Gattis WA, Borrello F, Wu E, O'Connor CM, Gheorghiade M. Effects of amino acid supplementation on left ventricular remodeling in patients with chronic heart failure with decreased systolic function and diabetes mellitus: rationale and design of a magnetic resonance imaging study. The American journal of cardiology 2004. PMID: 15094106

Klein L, Gheorghiade M. Management of the patient with diabetes mellitus and myocardial infarction: clinical trials update. The American journal of medicine 2004. PMID: 15019863

Piccini JP, Klein L, Gheorghiade M, Bonow RO. New insights into diastolic heart failure: role of diabetes mellitus. The American journal of medicine 2004. PMID: 15019864

Gheorghiade M, Klein L, Stone NJ, Bonow RO, Kim RJ. Improvement in the function of hibernating myocardium in a patient with heart failure due to coronary artery disease receiving high-dose simvastatin. Italian heart journal : official journal of the Italian Federation of Cardiology 2004. PMID: 15086148

Klein L, O'Connor CM, Gattis WA, Zampino M, de Luca L, Vitarelli A, Fedele F, Gheorghiade M. Pharmacologic therapy for patients with chronic heart failure and reduced systolic function: review of trials and practical considerations. The American journal of cardiology 2003. PMID: 12729848

Jain P, Massie BM, Gattis WA, Klein L, Gheorghiade M. Current medical treatment for the exacerbation of chronic heart failure resulting in hospitalization. American heart journal 2003. PMID: 12594447

Klein L, Gheorghiade M. Therapeutic strategies for patients hospitalized with worsening heart failure. Italian heart journal : official journal of the Italian Federation of Cardiology 2003. PMID: 12762267

Gheorghiade M, Gattis WA, Klein L. OPTIME in CHF trial: rethinking the use of inotropes in the management of worsening chronic heart failure resulting in hospitalization. European journal of heart failure 2003. PMID: 12559209

Borrello F, Beahan M, Klein L, Gheorghiade M. Reappraisal of beta-blocker therapy in the acute and chronic post-myocardial infarction period. Reviews in cardiovascular medicine 2003. PMID: 14564230