Laurence Huang, MD

Clinical Professor

I am a pulmonary and critical care medicine specialist with a research focus on pulmonary diseases affecting persons with HIV with a global perspective. I am a clinical-translational researcher with clinical cohorts in San Francisco, CA and in Kampala, Uganda.

Currently, I am PI/Co-PI on these main studies:

I AM OLD and I AM OLD-DA (renewal): The Inflammation, Aging, Microbes and Obstructive Lung Disease (I AM OLD) Study and The Inflammation, Aging, Microbes, Obstructive Lung Disease, and Diffusion Abnormalities (I AM OLD-DA) Study is a multi-cohort study with clinical sites in San Francisco and Kampala, Uganda, whose goal is to examine potential mechanisms for development of obstructive lung disease and progression of airflow obstruction and diffusion abnormalities in a multi-national cohort of HIV-infected subjects with opportunistic pneumonia.

I AM GOLD: The Integrated Analysis of Microbial and Genomic data in Obstructive Lung Disease (I AM GOLD) Study is a multi-cohort study with clinical sites in San Francisco and Kampala, Uganda, whose goal is to examine airway microbial communities (the lung microbiome) and inflammatory gene expression markers at the time of acute infection and during chronic stable disease that are associated with HIV-associated COPD and lung function decline in HIV and to perform integrative analyses of the airway microbiome, microbial and human transcriptome, metabolome and lung radiographic changes in HIV-associated COPD.

Recent, former studies:
IHOP: The International HIV-associated Opportunistic Pneumonias (IHOP) Study is a multi-national cohort study with clinical sites in San Francisco and Kampala, Uganda, whose goal is to improve our understanding of the epidemiology, etiology, and outcome of pneumonias in persons with HIV infection. IHOP was part of the Lung HIV Study, a collaborative multi-R01 consortium established by the National Heart, Lung, and Blood Institute (NHLBI) to examine a diverse range of infectious and non-infectious pulmonary diseases in HIV-infected persons.

Lung MicroCHIP: The Lung Microbiome in Cohorts of HIV-Infected Persons (Lung MicroChip) Study is a multi-cohort study with clinical sites in San Francisco and Kampala, Uganda, whose goal is to examine the composition and function of the lung microbiome in persons with HIV. Lung MicroChip was part of the Lung HIV Microbiome Project, a collaborative multi-U01 consortium established by the NHLBI to study the lung microbiome in HIV infection.

I am also involved in training the next generation of clinical and translational researchers at both fellowship and junior faculty levels, including through the following NIH-funded training programs:

Multidisciplinary Training Program in Lung Disease (NIH T32 HL007185): This is a continuation of the UCSF Multidisciplinary Training Program in Lung Disease, which provides training in basic and clinical sciences important to the respiratory system. The program draws on the basic and clinical research skills of the broad group of faculty at UCSF addressing questions directly relevant to lung biology and disease. The grant is to accommodate a total of 13 postdoctoral trainees, including both MDs and PhDs. The main program is an actual research experience under the close supervision of a Preceptor and a review committee selected on the basis of the experimental approaches of the trainee. These approaches include disciplines applicable at the molecular, cellular, tissue, organ, whole animal, clinical, or population levels.

CHIC (NIH K12 HL143961): The UCSF Career Development Program in Cardiopulmonary, Hematologic, and Immunologic Comorbidities of HIV (CHIC) is a K12 training grant whose goals are: (1) To recruit MD, MD/PhD and PhD scholars dedicated to independent research careers conducting clinical and translational research in HIV-related heart, lung, and blood research; (2) To design, implement, and monitor individualized and tailored research training and career development of these scholars using an interdisciplinary, team-science, and team-mentoring approach that combines didactic training in research methods with supervised research under the mentorship of an experienced faculty mentor and mentoring team; (3) To produce the ‘next generation’ of researchers in HIV-associated heart, lung and blood diseases.

Education
06/1995 - Pulmonary & Critical Care Medicine, University of California San Francisco
06/1992 - Internal Medicine, Columbia Presbyterian Medical Center
MD, 05/1989 - Medicine, Columbia College of Physicians & Surgeons
BA, 05/1985 - Biology, Johns Hopkins University
Honors and Awards
  • Division of Pulmonary and Critical Care Medicine V. Courtney Broaddus Leadership & Service Award, University of California San Francisco, 2023
  • World Lung Health Award, American Thoracic Society, 2022
  • Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine Outstanding Mentor Award, University of California San Francisco, 2019
  • Selected as American Thoracic Society Fellow, ATSF (inaugural class), American Thoracic Society, 2018
  • Microbiology, Tuberculosis, and Pulmonary Infections Assembly Senior-Level Peer Recognition Award, American Thoracic Society, 2017
  • UCSF Pathways to Discovery 2016-2017 Short-Term Mentor Award, University of California San Francisco, 2016-2017
  • Henry F. (Chip) Chambers Medicine Service Subspecialist Consultant of the Year Award, San Francisco General Hospital, 2014
  • Positive Health Program Award for Teaching Excellence-Meg Newman Teaching Award, University of California San Francisco, 2009
  • Haile T. Debas Academy of Medical Educators Excellence in Direct Teaching Award, University of California San Francisco, 2005
  • George S. Sarlo Award for Excellence in Teaching and Mentoring, University of California San Francisco AIDS Research Institute, 2005
  • James H. Nakano Citation (for Outstanding Scientific Paper published in 2000), Centers for Disease Control and Prevention, 2001
  • Community Based Teaching Excellence and Preceptorship Award, American College of Physicians-American Society of Internal Medicine, 2000
  • SFGH Positive Health Program Outstanding Teacher and Lecturer Award, San Francisco General Hospital, 2000
  • Elected as Fellow College of Chest Physicians (FCCP), American College of Chest Physicians, 1998
  • 4th Annual Steve Chase Humanitarian Award, Desert AIDS Project-presented to members of San Francisco General Hospital’s Inpatient AIDS Unit, 1998
  • Walter Travel Fund Award, American Lung Association, 1995
  • Omicron Delta Kappa-National Leadership Honor Society, Johns Hopkins University, 1984
Websites
Publications
  1. Zhang M, Dai G, Smith DL, Zacco E, Shimoda M, Kumar N, Girling V, Gardner K, Hunt PW, Huang L, Lin J. Interferon signaling pathways are upregulated in people with hiv with abnormal pulmonary diffusing capacity (DL CO ). AIDS (London, England) 2024. PMID: 38819840


  2. Curnow AC, Huang L, Fischl MA, Floris-Moore M, Morris A, Nouraie M, Reddy DB, Seaberg EC, Sheth AN, Tien PC, Wang RJ. Hepatitis C Virus Clearance and Diffusing Capacity for Carbon Monoxide in Women With and Without Human Immunodeficiency Virus. Open forum infectious diseases 2024. PMID: 38770208


  3. Musisi E, Wamutu S, Ssengooba W, Kasiinga S, Sessolo A, Sanyu I, Kaswabuli S, Zawedde J, Byanyima P, Kia P, Muwambi W, Toskin DT, Kigozi E, Walbaum N, Dombay E, Legrady MB, Ssemambo KD, Joloba M, Kuchaka D, Worodria W, Huang L, Gillespie SH, Sabiiti W. Accuracy of the tuberculosis molecular bacterial load assay to diagnose and monitor response to anti-tuberculosis therapy: a longitudinal comparative study with standard-of-care smear microscopy, Xpert MTB/RIF Ultra, and culture in Uganda. The Lancet. Microbe 2024. PMID: 38458206


  4. Abelman RA, Fitzpatrick J, Byanova KL, Zawedde J, Sanyu I, Byanyima P, Musisi E, Hsieh J, Zhang M, Branchini J, Sessolo A, Hunt PW, Lalitha R, Davis JL, Crothers K, Worodria W, Huang L. Sex and HIV Differences in Preserved Ratio Impaired Spirometry (PRISm) Among Ugandans Postpneumonia. Open forum infectious diseases 2024. PMID: 38456193


  5. Byanova KL, Abelman R, North CM, Christenson SA, Huang L. COPD in People with HIV: Epidemiology, Pathogenesis, Management, and Prevention Strategies. International journal of chronic obstructive pulmonary disease 2023. PMID: 38050482


  6. Konstantinidis I, Crothers K, Kunisaki KM, Drummond MB, Benfield T, Zar HJ, Huang L, Morris A. HIV-associated lung disease. Nature reviews. Disease primers 2023. PMID: 37500684


  7. Byanova KL, Fitzpatrick J, Jan AK, McGing M, Hartman-Filson M, Farr CK, Zhang M, Gardner K, Branchini J, Kerruish R, Bhide S, Bates A, Hsieh J, Abelman R, Hunt PW, Wang RJ, Crothers KA, Huang L. Isolated abnormal diffusing capacity for carbon monoxide (iso↓DLco) is associated with increased respiratory symptom burden in people with HIV infection. PloS one 2023. PMID: 37463173


  8. Abelman RA, Fitzpatrick J, Zawedde J, Sanyu I, Byanyima P, Kaswabuli S, Musisi E, Hsieh J, Gardner K, Zhang M, Byanova KL, Sessolo A, Hunt PW, Lalitha R, Davis JL, Crothers K, Worodria W, Huang L. Sex modifies the risk of HIV-associated obstructive lung disease in ugandans post-pneumonia. AIDS (London, England) 2023. PMID: 37352494


  9. Dunlap DG, Yang L, Qin S, Li K, Fitch A, Huang L, McVerry BJ, Hand TW, Methé BA, Morris A. Magnetic-activated cell sorting identifies a unique lung microbiome community. Microbiome 2023. PMID: 37226179


  10. Sessolo A, Musisi E, Kaswabuli S, Zawedde J, Byanyima P, Sabiiti W, Walimbwa S, Ola J, Sanyu I, Lalitha R, Kamya M, Davis L, Worodria W, Huang L. Diagnostic accuracy of Xpert MTB/RIF Ultra and culture assays to detect Mycobacterium Tuberculosis using OMNIgene-sputum processed stool among adult TB presumptive patients in Uganda. PloS one 2023. PMID: 37083706


  11. Wang RJ, Nouraie M, Kunisaki KM, Huang L, Tien PC, Anastos K, Bhandari N, Bhatt SP, Bolivar H, Cribbs SK, Foronjy R, Gange SJ, Lazarous D, Morris A, Drummond MB. Lung Function in Women with and without HIV. 2022. PMID: 35604821


  12. Drummond MB, Edmonds A, Ramirez C, Stosor V, Barjaktarevic IZ, Morris A, McCormack MC, Bhatt SP, Alcaide ML, Cribbs SK, D'Souza G, Bhandari N, Kunisaki KM, Huang L, Kassaye SG, Foronjy R, Sharma A, Westreich DJ, Adimora AA. Association Between HIV and Prevalence and Manifestations of Asthma: Analysis of the Multicenter AIDS Cohort Study and Women's Interagency HIV Study. Journal of acquired immune deficiency syndromes (1999) 2022. PMID: 36083508


  13. Konstantinidis I, Qin S, Fitzpatrick M, Kessinger C, Gentry H, McMahon D, Weinman RD, Tien P, Huang L, McCormack M, Barjaktarevic I, Reddy D, Foronjy R, Lazarous D, Cohen MH, McKay H, Adimora AA, Moran C, Fischl MA, Dionne-Odom J, Stosor V, Drummond MB, Cribbs SK, Kunisaki K, Rinaldo C, Morris A, Nouraie SM. Pulmonary Function Trajectories in People with HIV: Analysis of the Pittsburgh HIV Lung Cohort. Annals of the American Thoracic Society 2022. PMID: 35939796


  14. Byanyima P, Kaswabuli S, Musisi E, Nabakiibi C, Zawedde J, Sanyu I, Sessolo A, Andama A, Worodria W, Huang L, Davis JL. Feasibility and Sensitivity of Saliva GeneXpert MTB/RIF Ultra for Tuberculosis Diagnosis in Adults in Uganda. Microbiology spectrum 2022. PMID: 36154664


  15. Kaswabuli S, Musisi E, Byanyima P, Sessolo A, Sanyu I, Zawedde J, Worodria W, Huang L, Okeng A, Bwanga F. Accuracy of GenoQuick MTB test in detection of Mycobacterium tuberculosis in sputum from TB presumptive patients in Uganda. SAGE open medicine 2022. PMID: 35993094


  16. Cyktor J, Qin S, Staines B, Nouraie M, Fitzpatrick M, Kessinger C, DeSensi R, Huang L, Rinaldo CR, Kingsley L, Tien PC, Mellors JW, Morris A. Associations of HIV persistence, cigarette smoking, inflammation, and pulmonary dysfunction in people with HIV on antiretroviral therapy. Medicine 2022. PMID: 35801755


  17. Sellers SA, Edmonds A, Ramirez C, Cribbs SK, Ofotokun I, Huang L, Morris A, Mccormack MC, Kunisaki KM, D'souza G, Rivera MP, Drummond MB, Adimora AA. Optimal Lung Cancer Screening Criteria Among Persons Living With HIV. Journal of acquired immune deficiency syndromes (1999) 2022. PMID: 35125470


  18. Spottiswoode N, Bloomstein JD, Caldera S, Sessolo A, McCauley K, Byanyima P, Zawedde J, Kalantar K, Kaswabuli S, Rutishauser RL, Lieng MK, Davis JL, Moore J, Jan A, Iwai S, Shenoy M, Sanyu I, DeRisi JL, Lynch SV, Worodria W, Huang L, Langelier CR. Pneumonia surveillance with culture-independent metatranscriptomics in HIV-positive adults in Uganda: a cross-sectional study. 2022. PMID: 35544096


  19. Li W, Syed F, Yu R, Yang J, Xia Y, Relich RF, Russell PM, Zhang S, Khalili M, Huang L, Kacena MA, Zheng X, Yu Q. Soluble Immune Checkpoints Are Dysregulated in COVID-19 and Heavy Alcohol Users With HIV Infection. 2022. PMID: 35281051


  20. Musisi E, Sessolo A, Kaswabuli S, Zawedde J, Byanyima P, Kasinga S, Sanyu I, Uwimaana E, Walimbwa S, Olore J, Ssengooba W, Sekaggya C, Joloba ML, Worodria W, Huang L, Gillespie SH, Sloan DJ, Sabiiti W. High Mycobacterium tuberculosis Bacillary Loads Detected by Tuberculosis Molecular Bacterial Load Assay in Patient Stool: a Potential Alternative for Nonsputum Diagnosis and Treatment Response Monitoring of Tuberculosis. 2022. PMID: 35019686


  21. Akgün KM, Krishnan S, Butt AA, Gibert CL, Graber CJ, Huang L, Pisani MA, Rodriguez-Barradas MC, Hoo GWS, Justice AC, Crothers K, Tate JP. CD4+ cell count and outcomes among HIV-infected compared with uninfected medical ICU survivors in a national cohort. 2021. PMID: 34261095


  22. Zifodya JS, Triplette M, Shahrir S, Attia EF, Akgun KM, Soo Hoo GW, Rodriguez-Barradas MC, Wongtrakool C, Huang L, Crothers K. A cross-sectional analysis of diagnosis and management of chronic obstructive pulmonary disease in people living with HIV: Opportunities for improvement. 2021. PMID: 34664836


  23. Musisi E, Dide-Agossou C, Al Mubarak R, Rossmassler K, Ssesolo AW, Kaswabuli S, Byanyima P, Sanyu I, Zawedde J, Worodria W, Voskuil MI, Savic RM, Nahid P, Davis JL, Huang L, Moore CM, Walter ND. Reproducibility of the Ribosomal RNA Synthesis Ratio in Sputum and Association with Markers of Mycobacterium tuberculosis Burden. Microbiology spectrum 2021. PMID: 34494858


  24. Singhvi DG, Nouraie M, Kessinger C, McMahon DK, Weinman R, Crothers K, Huang L, Bon J, Morris A, Merlin J. Brief Report: Association Between Pain, Pulmonary Function, and Respiratory Symptoms in People With HIV. Journal of acquired immune deficiency syndromes (1999) 2021. PMID: 33871410


  25. Jan AK, Moore JV, Wang RJ, Mcging M, Farr CK, Moisi D, Hartman-Filson M, Kerruish R, Jeon D, Lewis E, Crothers K, Lederman MM, Hunt PW, Huang L. Markers of inflammation and immune activation are associated with lung function in a multi-center cohort of persons with HIV. AIDS (London, England) 2021. PMID: 33635847


  26. Walter ND, Born SEM, Robertson GT, Reichlen M, Dide-Agossou C, Ektnitphong VA, Rossmassler K, Ramey ME, Bauman AA, Ozols V, Bearrows SC, Schoolnik G, Dolganov G, Garcia B, Musisi E, Worodria W, Huang L, Davis JL, Nguyen NV, Nguyen HV, Nguyen ATV, Phan H, Wilusz C, Podell BK, Sanoussi ND, de Jong BC, Merle CS, Affolabi D, McIlleron H, Garcia-Cremades M, Maidji E, Eshun-Wilson F, Aguilar-Rodriguez B, Karthikeyan D, Mdluli K, Bansbach C, Lenaerts AJ, Savic RM, Nahid P, Vásquez JJ, Voskuil MI. Mycobacterium tuberculosis precursor rRNA as a measure of treatment-shortening activity of drugs and regimens. Nature communications 2021. PMID: 34006838


  27. Kuniholm MH, Bramah-Lawani M, Fitzpatrick M, Nouraie M, Qin S, Huang L, Vallejo AN, Landay AL, Morris A. Association of Monocyte Migration Marker CD11b With Pulmonary Function in People Living With HIV. Journal of acquired immune deficiency syndromes (1999) 2021. PMID: 33148999


  28. Meyer AJ, Ochom E, Turimumahoro P, Byanyima P, Sanyu I, Lalitha R, Kaswabuli S, Andama A, Walter ND, Katamba A, Cattamanchi A, Worodria W, Huang L, Yoon C, Davis JL. C-Reactive Protein Testing for Active Tuberculosis among Inpatients without HIV in Uganda: a Diagnostic Accuracy Study. Journal of clinical microbiology 2020. PMID: 33087439


  29. Byanova K, Kunisaki KM, Vasquez J, Huang L. Chronic obstructive pulmonary disease in HIV. Expert review of respiratory medicine 2020. PMID: 33167728


  30. Zifodya JS, Duncan MS, So-Armah KA, Attia EF, Akgün KM, Rodriguez-Barradas MC, Marconi VC, Budoff MJ, Bedimo RJ, Alcorn CW, Soo Hoo GW, Butt AA, Kim JW, Sico JJ, Tindle HA, Huang L, Tate JP, Justice AC, Freiberg MS, Crothers K. Community-Acquired Pneumonia and Risk of Cardiovascular Events in People Living With HIV. Journal of the American Heart Association 2020. PMID: 33222591


  31. Wenger DS, Triplette M, Shahrir S, Akgun KM, Wongtrakool C, Brown ST, Kim JW, Soo Hoo GW, Rodriguez-Barradas MC, Huang L, Feemster LC, Zifodya J, Crothers K. Associations of marijuana with markers of chronic lung disease in people living with HIV. HIV medicine 2020. PMID: 33022830


  32. Bhadriraju S, Fadrosh DW, Shenoy MK, Lin DL, Lynch KV, McCauley K, Ferrand RA, Majonga ED, McHugh G, Huang L, Lynch SV, Metcalfe JZ. Distinct lung microbiota associate with HIV-associated chronic lung disease in children. Scientific Reports 2020. PMID: 32999331


  33. Wang RJ, Katha G, Phiri M, Delbridge P, Gordon SB, Calfee CS, Huang L, Rylance J. Sonographic B-lines, Fluid Resuscitation, and Hypoxemia in Malawian Patients with Suspected Sepsis. American journal of respiratory and critical care medicine 2020. PMID: 32286847


  34. Rodriguez-Barradas MC, McGinnis KA, Akgün K, Tate JP, Brown ST, Butt AA, Fine M, Goetz MB, Graber CJ, Huang L, Rimland D, Justice A, Crothers K. Validation for using electronic health records to identify community acquired pneumonia hospitalization among people with and without HIV. Pneumonia (Nathan Qld.) 2020. PMID: 32724760


  35. Almodovar S, Wade BE, Porter KM, Smith JM, Lopez-Astacio RA, Bijli K, Kang BY, Cribbs SK, Guidot DM, Molehin D, McNair BK, Pumarejo-Gomez L, Perez Hernandez J, Salazar EA, Martinez EG, Huang L, Kessing CF, Suarez-Martinez EB, Pruitt K, Hsue PY, Tyor WR, Flores SC, Sutliff RL. HIV X4 Variants Increase Arachidonate 5-Lipoxygenase in the Pulmonary Microenvironment and are associated with Pulmonary Arterial Hypertension. Scientific Reports 2020. PMID: 32678115


  36. Qin S, Vodovotz L, Zamora R, Fitzpatrick M, Kessinger C, Kingsley L, McMahon D, DeSensi R, Leader JK, Crothers K, Huang L, Morris A, Nouraie M. Association Between Inflammatory Pathways and Phenotypes of Pulmonary Dysfunction Using Cluster Analysis in Persons Living With HIV and HIV-Uninfected Individuals. Journal of acquired immune deficiency syndromes (1999) 2020. PMID: 31929407


  37. Jeon D, Chang EG, McGing M, Hartman-Filson M, Sommers M, Lewis E, Balmes JR, Moisi D, Lederman MM, Madsen KA, Woodruff PG, Hunt PW, Huang L. Pneumoproteins are associated with pulmonary function in HIV-infected persons. PloS one 2019. PMID: 31574118


  38. North CM, Attia EF, Rudd KE, Siddharthan T, Papali A, Çoruh B, Carter EJ, Christiani DC, Richards JB, Huang L, Engelberg R, Checkley W, West TE. Global Health-related Training Opportunities. A National Survey of Pulmonary and Critical Care Medicine Fellowship Programs. Annals of the American Thoracic Society 2019. PMID: 31199665


  39. Wang S, Chang E, Byanyima P, Huang P, Sanyu I, Musisi E, Sessolo A, Davis JL, Worodria W, Huang L, Lin J. Association between common telomere length genetic variants and telomere length in an African population and impacts of HIV and TB. Journal of human genetics 2019. PMID: 31388112


  40. Wang RJ, Moore J, Moisi D, Chang EG, Byanyima P, Kaswabuli S, Musisi E, Sanyu I, Sessolo A, Lalitha R, Worodria W, Davis JL, Crothers K, Lin J, Lederman MM, Hunt PW, Huang L. HIV infection is associated with elevated biomarkers of immune activation in Ugandan adults with pneumonia. PloS one 2019. PMID: 31091258


  41. Robertson TE, Nouraie M, Qin S, Crothers KA, Kessinger CJ, McMahon D, Chandra D, Kingsley LA, Greenblatt RM, Huang L, Fitzpatrick ME, Morris A. HIV infection is an independent risk factor for decreased 6-minute walk test distance. PloS one 2019. PMID: 31017909


  42. Shenoy MK, Fadrosh DW, Lin DL, Worodria W, Byanyima P, Musisi E, Kaswabuli S, Zawedde J, Sanyu I, Chang E, Fong S, McCauley K, Davis JL, Huang L, Lynch SV. Gut microbiota in HIV-pneumonia patients is related to peripheral CD4 counts, lung microbiota, and in vitro macrophage dysfunction. Microbiome 2019. PMID: 30857553


  43. Rentsch CT, Tate JP, Steel T, Butt AA, Gibert CL, Huang L, Pisani M, Soo Hoo GW, Crystal S, Rodriguez-Barradas MC, Brown ST, Freiberg MS, Graber CJ, Kim JW, Rimland D, Justice AC, Fiellin DA, Crothers KA, Akgün KM. Medical Intensive Care Unit Admission Among Patients With and Without HIV, Hepatitis C Virus, and Alcohol-Related Diagnoses in the United States: A National, Retrospective Cohort Study, 1997-2014. Journal of acquired immune deficiency syndromes (1999) 2019. PMID: 30422912


  44. Worodria W, Chang E, Andama A, Sanyu I, Byanyima P, Musisi E, Kaswabuli S, Zawedde J, Ayakaka I, Sessolo A, Lalitha R, Davis JL, Huang L. Predictors of Mortality Among Hospitalized Patients With Lower Respiratory Tract Infections in a High HIV Burden Setting. Journal of acquired immune deficiency syndromes (1999) 2018. PMID: 30222660


  45. Li Y, Nouraie SM, Kessinger C, Weinman R, Huang L, Greenblatt RM, Kleerup E, Kingsley L, McMahon D, Fitzpatrick M, Morris A. Factors Associated With Progression of Lung Function Abnormalities in HIV-Infected Individuals. Journal of acquired immune deficiency syndromes (1999) 2018. PMID: 30142142


  46. Farr K, Ravindran R, Strnad L, Chang E, Chaisson LH, Yoon C, Worodria W, Andama A, Ayakaka I, Bbosa Nalwanga P, Byanyima P, Kalema N, Kaswabuli S, Katagira W, Aman KD, Musisi E, Tumwine NW, Sanyu I, Ssebunya R, Davis JL, Huang L, Khan IH, Cattamanchi A. Diagnostic performance of blood inflammatory markers for tuberculosis screening in people living with HIV. PloS one 2018. PMID: 30352099


  47. Qin S, Clausen E, Nouraie SM, Kingsley L, McMahon D, Kleerup E, Huang L, Ghedin E, Greenblatt RM, Morris A. Tropheryma whipplei colonization in HIV-infected individuals is not associated with lung function or inflammation. PloS one 2018. PMID: 30286195


  48. Musisi E, Matovu DK, Bukenya A, Kaswabuli S, Zawedde J, Andama A, Byanyima P, Sanyu I, Sessolo A, Seremba E, Davis JL, Worodria W, Huang L, Walter ND, Mayanja-Kizza H. Effect of anti-retroviral therapy on oxidative stress in hospitalized HIV-infected adults with and without TB. African health sciences 2018. PMID: 30602982


  49. Walter ND, Moore CM, Kayigire XA, Dide-Agossou C, Worodria W, Huang L, Everett CK, Schoolnik GS, Nahid P, Davis JL. Does discovery of differentially culturable M tuberculosis really demand a new treatment paradigm? Longitudinal analysis of DNA clearance from sputum. BMC infectious diseases 2018. PMID: 29970012


  50. Tipton L, Cuenco KT, Huang L, Greenblatt RM, Kleerup E, Sciurba F, Duncan SR, Donahoe MP, Morris A, Ghedin E. Measuring associations between the microbiota and repeated measures of continuous clinical variables using a lasso-penalized generalized linear mixed model. BioData mining 2018. PMID: 29983746


  51. Gingo MR, Nouraie M, Kessinger CJ, Greenblatt RM, Huang L, Kleerup EC, Kingsley L, McMahon DK, Morris A. Decreased Lung Function and All-Cause Mortality in HIV-infected Individuals. Annals of the American Thoracic Society 2018. PMID: 29313714


  52. Tipton L, Müller CL, Kurtz ZD, Huang L, Kleerup E, Morris A, Bonneau R, Ghedin E. Fungi stabilize connectivity in the lung and skin microbial ecosystems. Microbiome 2018. PMID: 29335027


  53. Block BL, Mehta T, Ortiz GM, Ferris SP, Vu TH, Huang L, Cattamanchi A. Unusual Radiographic Presentation of Pneumocystis Pneumonia in a Patient with AIDS. Case reports in infectious diseases 2017. PMID: 29362681


  54. Yoon C, Semitala FC, Atuhumuza E, Katende J, Mwebe S, Asege L, Armstrong DT, Andama AO, Dowdy DW, Davis JL, Huang L, Kamya M, Cattamanchi A. Point-of-care C-reactive protein-based tuberculosis screening for people living with HIV: a diagnostic accuracy study. Volume 17 of Issue 12. The Lancet. Infectious diseases 2017. PMID: 28847636


  55. Shete PB, Ravindran R, Chang E, Worodria W, Chaisson LH, Andama A, Davis JL, Luciw PA, Huang L, Khan IH, Cattamanchi A. Evaluation of antibody responses to panels of M. tuberculosis antigens as a screening tool for active tuberculosis in Uganda. Volume 12 of Issue 8. PloS one 2017. PMID: 28767658


  56. Blount RJ, Daly KR, Fong S, Chang E, Grieco K, Greene M, Stone S, Balmes J, Miller RF, Walzer PD, Huang L. Effects of clinical and environmental factors on bronchoalveolar antibody responses to Pneumocystis jirovecii: A prospective cohort study of HIV+ patients. Volume 12 of Issue 7. PloS one 2017. PMID: 28692651


  57. Meyer AJ, Atuheire C, Worodria W, Kizito S, Katamba A, Sanyu I, Andama A, Ayakaka I, Cattamanchi A, Bwanga F, Huang L, Davis JL. Sputum quality and diagnostic performance of GeneXpert MTB/RIF among smear-negative adults with presumed tuberculosis in Uganda. Volume 12 of Issue 7. PloS one 2017. PMID: 28686705


  58. Wang RJ, Miller RF, Huang L. Approach to Fungal Infections in Human Immunodeficiency Virus-Infected Individuals: Pneumocystis and Beyond. Clinics in chest medicine 2017. PMID: 28797489


  59. Kelly-Cirino CD, Musisi E, Byanyima P, Kaswabuli S, Andama A, Sessolo A, Sanyu I, Zawedde J, Curry PS, Huang L. Investigation of OMNIgene·SPUTUM performance in delayed tuberculosis testing by smear, culture, and Xpert MTB/RIF assays in Uganda. Journal of epidemiology and global health 2017. PMID: 28413105


  60. Morris A, Fitzpatrick M, Bertolet M, Qin S, Kingsley L, Leo N, Kessinger C, Michael H, Mcmahon D, Weinman R, Stone S, Leader JK, Kleerup E, Huang L, Wisniewski SR. Use of rosuvastatin in HIV-associated chronic obstructive pulmonary disease. AIDS (London, England) 2017. PMID: 27941393


  61. Triplette M, Attia EF, Akgün KM, Soo Hoo GW, Freiberg MS, Butt AA, Wongtrakool C, Goetz MB, Brown ST, Graber CJ, Huang L, Crothers K. A Low Peripheral Blood CD4/CD8 Ratio Is Associated with Pulmonary Emphysema in HIV. PloS one 2017. PMID: 28122034


  62. Ponce CA, Chabé M, George C, Cárdenas A, Durán L, Guerrero J, Bustamante R, Matos O, Huang L, Miller RF, Vargas SL. High Prevalence of Pneumocystis jirovecii Dihydropteroate Synthase Gene Mutations in Patients with a First Episode of Pneumocystis Pneumonia in Santiago, Chile, and Clinical Response to Trimethoprim-Sulfamethoxazole Therapy. Antimicrobial agents and chemotherapy 2017. PMID: 27855071


  63. Shenoy MK, Iwai S, Lin DL, Worodria W, Ayakaka I, Byanyima P, Kaswabuli S, Fong S, Stone S, Chang E, Davis JL, Faruqi AA, Segal MR, Huang L, Lynch SV. Immune Response and Mortality Risk Relate to Distinct Lung Microbiomes in Patients with HIV and Pneumonia. Volume 195 of Issue 1. American journal of respiratory and critical care medicine 2017. PMID: 27447987


  64. Kalema N, Lindan C, Glidden D, Yoo SD, Katamba A, Alfred A, Katagira W, Byanyima P, Musisi E, Kaswabuli S, Ingvar S, Zawedde J, Yoon C, Ayakaka I, Davis JL, Huang L, Worodria W, Cattamanchi A. Predictors and short-term outcomes of recurrent pulmonary tuberculosis, Uganda: a cohort study. Volume 23 of Issue 4. South African respiratory journal 2017. PMID: 29368752


  65. Auld E, Lin J, Chang E, Byanyima P, Ayakaka I, Musisi E, Worodria W, Davis JL, Segal M, Blackburn E, Huang L. HIV Infection Is Associated with Shortened Telomere Length in Ugandans with Suspected Tuberculosis. PloS one 2016. PMID: 27655116


  66. Walter ND, de Jong BC, Garcia BJ, Dolganov GM, Worodria W, Byanyima P, Musisi E, Huang L, Chan ED, Van TT, Antonio M, Ayorinde A, Kato-Maeda M, Nahid P, Leung AM, Yen A, Fingerlin TE, Kechris K, Strong M, Voskuil MI, Davis JL, Schoolnik GK. Adaptation of Mycobacterium tuberculosis to Impaired Host Immunity in HIV-Infected Patients. The Journal of infectious diseases 2016. PMID: 27534685


  67. Katagira W, Walter ND, Den Boon S, Kalema N, Ayakaka I, Vittinghoff E, Worodria W, Cattamanchi A, Huang L, Davis JL. Empiric TB Treatment of Severely Ill Patients With HIV and Presumed Pulmonary TB Improves Survival. Volume 72 of Issue 3. Journal of acquired immune deficiency syndromes (1999) 2016. PMID: 26918546


  68. Segal LN, Clemente JC, Tsay JC, Koralov SB, Keller BC, Wu BG, Li Y, Shen N, Ghedin E, Morris A, Diaz P, Huang L, Wikoff WR, Ubeda C, Artacho A, Rom WN, Sterman DH, Collman RG, Blaser MJ, Weiden MD. Enrichment of the lung microbiome with oral taxa is associated with lung inflammation of a Th17 phenotype. Nature microbiology 2016. PMID: 27572644


  69. Leader JK, Crothers K, Huang L, King MA, Morris A, Thompson BW, Flores SC, Drummond MB, Rom WN, Diaz PT. Risk Factors Associated With Quantitative Evidence of Lung Emphysema and Fibrosis in an HIV-Infected Cohort. Journal of acquired immune deficiency syndromes (1999) 2016. PMID: 26914911


  70. Esteves F, de Sousa B, Calderón EJ, Huang L, Badura R, Maltez F, Bassat Q, de Armas Y, Antunes F, Matos O. Multicentre study highlighting clinical relevance of new high-throughput methodologies in molecular epidemiology of Pneumocystis jirovecii pneumonia. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2016. PMID: 27021425


  71. Maximous S, Huang L, Morris A. Evaluation and Diagnosis of HIV-Associated Lung Disease. Seminars in respiratory and critical care medicine 2016. PMID: 26974298


  72. Drummond MB, Kunisaki KM, Huang L. Obstructive Lung Diseases in HIV: A Clinical Review and Identification of Key Future Research Needs. Seminars in respiratory and critical care medicine 2016. PMID: 26974304


  73. Huang L, Morris A, Crothers K. Pulmonary Complications of HIV Infection. Seminars in respiratory and critical care medicine 2016. PMID: 26974293


  74. Cribbs SK, Uppal K, Li S, Jones DP, Huang L, Tipton L, Fitch A, Greenblatt RM, Kingsley L, Guidot DM, Ghedin E, Morris A. Correlation of the lung microbiota with metabolic profiles in bronchoalveolar lavage fluid in HIV infection. Microbiome 2016. PMID: 26792212


  75. Beck JM, Schloss PD, Venkataraman A, Twigg H, Jablonski KA, Bushman FD, Campbell TB, Charlson ES, Collman RG, Crothers K, Curtis JL, Drews KL, Flores SC, Fontenot AP, Foulkes MA, Frank I, Ghedin E, Huang L, Lynch SV, Morris A, Palmer BE, Schmidt TM, Sodergren E, Weinstock GM, Young VB. Multicenter Comparison of Lung and Oral Microbiomes of HIV-infected and HIV-uninfected Individuals. Volume 192 of Issue 11. American journal of respiratory and critical care medicine 2015. PMID: 26247840


  76. Attia EF, McGinnis KA, Feemster LC, Akgün KM, Butt AA, Graber CJ, Fine MJ, Goetz MB, Rodriguez-Barradas MC, Pisani MA, Tindle HA, Brown ST, Soo Hoo GW, Rimland D, Gibert CL, Huang L, Freiberg MS, Hough CL, Crothers K. Association of COPD With Risk for Pulmonary Infections Requiring Hospitalization in HIV-Infected Veterans. Journal of acquired immune deficiency syndromes (1999) 2015. PMID: 26181820


  77. Drummond MB, Huang L, Diaz PT, Kirk GD, Kleerup EC, Morris A, Rom W, Weiden MD, Zhao E, Thompson B, Crothers K. Factors associated with abnormal spirometry among HIV-infected individuals. AIDS (London, England) 2015. PMID: 26372280


  78. Juliano JJ, Barnett E, Parobek CM, Taylor SM, Meshnick SR, Stone S, Chang E, Fong S, Huang L. Use of Oropharyngeal Washes to Diagnose and Genotype Pneumocystis jirovecii. Open forum infectious diseases 2015. PMID: 26180832


  79. Koss CA, Jarlsberg LG, den Boon S, Cattamanchi A, Davis JL, Worodria W, Ayakaka I, Sanyu I, Huang L. A Clinical Predictor Score for 30-Day Mortality among HIV-Infected Adults Hospitalized with Pneumonia in Uganda. Volume 10 of Issue 5. PloS one 2015. PMID: 25962069


  80. Semitala FC, Chaisson LH, den Boon S, Walter N, Cattamanchi A, Awor M, Katende J, Huang L, Joloba M, Albert H, Kamya MR, Davis JL. Impact of mycobacterial culture among HIV-infected adults with presumed TB in Uganda: a prospective cohort study. Public health action 2015. PMID: 26400379


  81. Cui L, Lucht L, Tipton L, Rogers MB, Fitch A, Kessinger C, Camp D, Kingsley L, Leo N, Greenblatt RM, Fong S, Stone S, Dermand JC, Kleerup EC, Huang L, Morris A, Ghedin E. Topographic diversity of the respiratory tract mycobiome and alteration in HIV and lung disease. American journal of respiratory and critical care medicine 2015. PMID: 25603113


  82. Walter ND, Dolganov GM, Garcia BJ, Worodria W, Andama A, Musisi E, Ayakaka I, Van TT, Voskuil MI, de Jong BC, Davidson RM, Fingerlin TE, Kechris K, Palmer C, Nahid P, Daley CL, Geraci M, Huang L, Cattamanchi A, Strong M, Schoolnik GK, Davis JL. Transcriptional Adaptation of Drug-tolerant Mycobacterium tuberculosis During Treatment of Human Tuberculosis. Volume 212 of Issue 6. The Journal of infectious diseases 2015. PMID: 25762787


  83. Simonetti JA, Gingo MR, Kingsley L, Kessinger C, Lucht L, Balasubramani G, Leader JK, Huang L, Greenblatt RM, Dermand J, Kleerup EC, Morris A. Pulmonary Function in HIV-Infected Recreational Drug Users in the Era of Anti-Retroviral Therapy. Journal of AIDS & clinical research 2014. PMID: 25664201


  84. Cui L, Morris A, Huang L, Beck JM, Twigg HL, von Mutius E, Ghedin E. The microbiome and the lung. Annals of the American Thoracic Society 2014. PMID: 25148429


  85. Gingo MR, Balasubramani GK, Rice TB, Kingsley L, Kleerup EC, Detels R, Seaberg EC, Greenblatt RM, Holman S, Huang L, Sutton SH, Bertolet M, Morris A. Pulmonary symptoms and diagnoses are associated with HIV in the MACS and WIHS cohorts. BMC pulmonary medicine 2014. PMID: 24884738


  86. Iwai S, Huang D, Fong S, Jarlsberg LG, Worodria W, Yoo S, Cattamanchi A, Davis JL, Kaswabuli S, Segal M, Huang L, Lynch SV. The lung microbiome of Ugandan HIV-infected pneumonia patients is compositionally and functionally distinct from that of San Franciscan patients. Volume 9 of Issue 4. PloS one 2014. PMID: 24752365


  87. Campo M, Oursler KK, Huang L, Goetz MB, Rimland D, Hoo GS, Brown ST, Rodriguez-Barradas MC, Au D, Akgün KM, Shahrir S, Crothers K. Association of chronic cough and pulmonary function with 6-minute walk test performance in HIV infection. Journal of acquired immune deficiency syndromes (1999) 2014. PMID: 24346638


  88. Yoon C, Davis JL, Huang L, Muzoora C, Byakwaga H, Scibetta C, Bangsberg DR, Nahid P, Semitala FC, Hunt PW, Martin JN, Cattamanchi A. Point-of-care C-reactive protein testing to facilitate implementation of isoniazid preventive therapy for people living with HIV. Volume 65 of Issue 5. Journal of acquired immune deficiency syndromes (1999) 2014. PMID: 24346636


  89. Parobek CM, Jiang LY, Patel JC, Alvarez-Martínez MJ, Miro JM, Worodria W, Andama A, Fong S, Huang L, Meshnick SR, Taylor SM, Juliano JJ. Multilocus microsatellite genotyping array for investigation of genetic epidemiology of Pneumocystis jirovecii. Journal of clinical microbiology 2014. PMID: 24523468


  90. Tokman S, Barnett CF, Jarlsberg LG, Taub PR, den Boon S, Davis JL, Cattamanchi A, Worodria W, Maisel A, Huang L. Procalcitonin predicts mortality in HIV-infected Ugandan adults with lower respiratory tract infections. Volume 19 of Issue 3. Respirology (Carlton, Vic.) 2014. PMID: 24460728


  91. Blount RJ, Djawe K, Daly KR, Jarlsberg LG, Fong S, Balmes J, Miller RF, Walzer PD, Huang L. Ambient air pollution associated with suppressed serologic responses to Pneumocystis jirovecii in a prospective cohort of HIV-infected patients with Pneumocystis pneumonia. Volume 8 of Issue 11. PloS one 2013. PMID: 24236202


  92. Fitzpatrick ME, Gingo MR, Kessinger C, Lucht L, Kleerup E, Greenblatt RM, Claman D, Ponath C, Fong S, Huang L, Morris A. HIV infection is associated with diffusing capacity impairment in women. Journal of acquired immune deficiency syndromes (1999) 2013. PMID: 23979000


  93. Crothers K, McGinnis K, Kleerup E, Wongtrakool C, Hoo GS, Kim J, Sharafkhaneh A, Huang L, Luo Z, Thompson B, Diaz P, Kirk GD, Rom W, Detels R, Kingsley L, Morris A. HIV infection is associated with reduced pulmonary diffusing capacity. Journal of acquired immune deficiency syndromes (1999) 2013. PMID: 23979001


  94. Fong S, Daly KR, Tipirneni R, Jarlsberg LG, Djawe K, Koch JV, Swartzman A, Roth B, Walzer PD, Huang L. Antibody responses against Pneumocystis jirovecii in health care workers over time. Emerging infectious diseases 2013. PMID: 24048016


  95. Twigg HL, Morris A, Ghedin E, Curtis JL, Huffnagle GB, Crothers K, Campbell TB, Flores SC, Fontenot AP, Beck JM, Huang L, Lynch S, Knox KS, Weinstock G. Use of bronchoalveolar lavage to assess the respiratory microbiome: signal in the noise. The Lancet. Respiratory medicine 2013. PMID: 24429191


  96. Huang YJ, Charlson ES, Collman RG, Colombini-Hatch S, Martinez FD, Senior RM. The role of the lung microbiome in health and disease. A National Heart, Lung, and Blood Institute workshop report. American journal of respiratory and critical care medicine 2013. PMID: 23614695


  97. Akgün KM, Tate JP, Pisani M, Fried T, Butt AA, Gibert CL, Huang L, Rodriguez-Barradas MC, Rimland D, Justice AC, Crothers K. Medical ICU admission diagnoses and outcomes in human immunodeficiency virus-infected and virus-uninfected veterans in the combination antiretroviral era. Critical care medicine 2013. PMID: 23507717


  98. Andama AO, den Boon S, Meya D, Cattamanchi A, Worodria W, Davis JL, Walter ND, Yoo SD, Kalema N, Haller B, Huang L. Prevalence and outcomes of cryptococcal antigenemia in HIV-seropositive patients hospitalized for suspected tuberculosis in Uganda. Volume 63 of Issue 2. Journal of acquired immune deficiency syndromes (1999) 2013. PMID: 23542636


  99. Crothers K, Huang L, Morris A. Recent global estimates indicate that approximately 34 million people are living with HIV infection. Introduction. Clinics in chest medicine 2013. PMID: 23702181


  100. Morris A, Beck JM, Schloss PD, Campbell TB, Crothers K, Curtis JL, Flores SC, Fontenot AP, Ghedin E, Huang L, Jablonski K, Kleerup E, Lynch SV, Sodergren E, Twigg H, Young VB, Bassis CM, Venkataraman A, Schmidt TM, Weinstock GM. Comparison of the respiratory microbiome in healthy nonsmokers and smokers. Volume 187 of Issue 10. American journal of respiratory and critical care medicine 2013. PMID: 23491408


  101. Lozupone C, Cota-Gomez A, Palmer BE, Linderman DJ, Charlson ES, Sodergren E, Mitreva M, Abubucker S, Martin J, Yao G, Campbell TB, Flores SC, Ackerman G, Stombaugh J, Ursell L, Beck JM, Curtis JL, Young VB, Lynch SV, Huang L, Weinstock GM, Knox KS, Twigg H, Morris A, Ghedin E, Bushman FD, Collman RG, Knight R, Fontenot AP. Widespread colonization of the lung by Tropheryma whipplei in HIV infection. Volume 187 of Issue 10. American journal of respiratory and critical care medicine 2013. PMID: 23392441


  102. Everett CK, Subramanian A, Jarisberg LG, Fei M, Huang L. Characteristics of Drug-Susceptible and Drug-Resistant Staphylococcus aureus Pneumonia in Patients with HIV. Epidemiology (Sunnyvale, Calif.) 2013. PMID: 25346868


  103. Tokman S, Huang L. Evaluation of respiratory disease. Clinics in chest medicine 2013. PMID: 23702170


  104. Miller RF, Huang L, Walzer PD. Pneumocystis pneumonia associated with human immunodeficiency virus. Clinics in chest medicine 2013. PMID: 23702173


  105. Tapley A, Switz N, Reber C, Davis JL, Miller C, Matovu JB, Worodria W, Huang L, Fletcher DA, Cattamanchi A. Mobile digital fluorescence microscopy for diagnosis of tuberculosis. Volume 51 of Issue 6. Journal of clinical microbiology 2013. PMID: 23554191


  106. Gingo MR, Balasubramani GK, Kingsley L, Rinaldo CR, Alden CB, Detels R, Greenblatt RM, Hessol NA, Holman S, Huang L, Kleerup EC, Phair J, Sutton SH, Seaberg EC, Margolick JB, Wisniewski SR, Morris A. The impact of HAART on the respiratory complications of HIV infection: longitudinal trends in the MACS and WIHS cohorts. PloS one 2013. PMID: 23554932


  107. Yoon C, Subramanian A, Chi A, Crothers K, Meshnick SR, Taylor SM, Beard CB, Jarlsberg LG, Lawrence GG, Avery M, Swartzman A, Fong S, Roth B, Huang L. Dihydropteroate synthase mutations in Pneumocystis pneumonia: impact of applying different definitions of prophylaxis, mortality endpoints and mutant in a single cohort. Volume 51 of Issue 6. Medical mycology 2013. PMID: 23470037


  108. Baxi S, Platts-Mills J, Dhruva S, Huang L, Hanks D, Dhaliwal G. A double-edged sword. Journal of hospital medicine 2013. PMID: 23293015


  109. Akgün KM, Gordon K, Pisani M, Fried T, McGinnis KA, Tate JP, Butt AA, Gibert CL, Huang L, Rodriguez-Barradas MC, Rimland D, Justice AC, Crothers K. Risk factors for hospitalization and medical intensive care unit (MICU) admission among HIV-infected Veterans. Journal of acquired immune deficiency syndromes (1999) 2013. PMID: 23111572


  110. Huang, YJ, Charlson, ES, Collman, RG, Colombini-Hatch, S, Martinez, FD and Senior, RM. The role of the lung microbiome in health and disease. A National Heart, Lung, and Blood Institute workshop report Am J Respir Crit Care Med 2013. PMID:


  111. Blount RJ, Jarlsberg LG, Daly KR, Worodria W, Davis JL, Cattamanchi A, Djawe K, Andama A, Koch J, Walzer PD, Huang L. Serologic responses to recombinant Pneumocystis jirovecii major surface glycoprotein among Ugandan patients with respiratory symptoms. PloS one 2012. PMID: 23284710


  112. Taylor SM, Meshnick SR, Worodria W, Andama A, Cattamanchi A, Davis JL, Yoo SD, Byanyima P, Kaswabuli S, Goodman CD, Huang L. Low prevalence of Pneumocystis pneumonia (PCP) but high prevalence of pneumocystis dihydropteroate synthase (dhps) gene mutations in HIV-infected persons in Uganda. Volume 7 of Issue 11. PloS one 2012. PMID: 23166805


  113. Yoon C, Cattamanchi A, Davis JL, Worodria W, den Boon S, Kalema N, Katagira W, Kaswabuli S, Miller C, Andama A, Albert H, Nabeta P, Gray C, Ayakaka I, Huang L. Impact of Xpert MTB/RIF testing on tuberculosis management and outcomes in hospitalized patients in Uganda. Volume 7 of Issue 11. PloS one 2012. PMID: 23139799


  114. Djawe K, Levin L, Swartzman A, Fong S, Roth B, Subramanian A, Grieco K, Jarlsberg L, Miller RF, Huang L, Walzer PD. Environmental risk factors for Pneumocystis pneumonia hospitalizations in HIV patients. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2012. PMID: 23042978


  115. Nakiyingi L, Kateete DP, Ocama P, Worodria W, Sempa JB, Asiimwe BB, Katabazi FA, Katamba A, Huang L, Joloba ML, Mayanja-Kizza H. Evaluation of in-house PCR for diagnosis of smear-negative pulmonary tuberculosis in Kampala, Uganda. BMC research notes 2012. PMID: 22947399


  116. Kalema N, Boon SD, Cattamanchi A, Davis JL, Andama A, Katagira W, Everett C, Walter N, Byanyima P, Kaswabuli S, Worodria W, Huang L. Oral antimicrobial rinse to reduce mycobacterial culture contamination among tuberculosis suspects in Uganda: a prospective study. Volume 7 of Issue 7. PloS one 2012. PMID: 22808020


  117. Iwai S, Fei M, Huang D, Fong S, Subramanian A, Grieco K, Lynch SV, Huang L. Oral and airway microbiota in HIV-infected pneumonia patients. Volume 50 of Issue 9. Journal of clinical microbiology 2012. PMID: 22760045


  118. Cattamanchi A, Ssewenyana I, Nabatanzi R, Miller CR, Den Boon S, Davis JL, Andama A, Worodria W, Yoo SD, Cao H, Huang L. Bronchoalveolar lavage enzyme-linked immunospot for diagnosis of smear-negative tuberculosis in HIV-infected patients. Volume 7 of Issue 6. PloS one 2012. PMID: 22745833


  119. Feldman MD, Steinauer JE, Khalili M, Huang L, Kahn JS, Lee KA, Creasman J, Brown JS. A mentor development program for clinical translational science faculty leads to sustained, improved confidence in mentoring skills. Clinical and translational science 2012. PMID: 22883616


  120. Taylor SM, Meshnick SR, Worodria W, Andama A, Davis JL, Cattamanchi A, den Boon S, Yoo SD, Goodman CD, Huang L. Low prevalence of Pneumocystis jirovecii lung colonization in Ugandan HIV-infected patients hospitalized with non-Pneumocystis pneumonia. Volume 72 of Issue 2. Diagnostic microbiology and infectious disease 2011. PMID: 22153850


  121. Metcalfe JZ, Everett CK, Steingart KR, Cattamanchi A, Huang L, Hopewell PC, Pai M. Interferon-? release assays for active pulmonary tuberculosis diagnosis in adults in low- and middle-income countries: systematic review and meta-analysis. Volume 204 Suppl 4. The Journal of infectious diseases 2011. PMID: 21996694


  122. Worodria W, Anderson J, Cattamanchi A, Davis JL, den Boon S, Andama A, Yoo SD, Joloba M, Huang L, Kato-Maeda M. The role of speciation in positive Lowenstein-Jensen culture isolates from a high tuberculosis burden country. Volume 6 of Issue 11. PloS one 2011. PMID: 22073241


  123. Kisembo HN, Boon SD, Davis JL, Okello R, Worodria W, Cattamanchi A, Huang L, Kawooya MG. Chest radiographic findings of pulmonary tuberculosis in severely immunocompromised patients with the human immunodeficiency virus. The British journal of radiology 2011. PMID: 21976629


  124. Yoo SD, Cattamanchi A, Den Boon S, Worodria W, Kisembo H, Huang L, Davis JL. Clinical significance of normal chest radiographs among HIV-seropositive patients with suspected tuberculosis in Uganda. Volume 16 of Issue 5. Respirology (Carlton, Vic.) 2011. PMID: 21518124


  125. Akgün KM, Huang L, Morris A, Justice AC, Pisani M, Crothers K. Critical illness in HIV-infected patients in the era of combination antiretroviral therapy. Proceedings of the American Thoracic Society 2011. PMID: 21653532


  126. Morris A, George MP, Crothers K, Huang L, Lucht L, Kessinger C, Kleerup EC. HIV and chronic obstructive pulmonary disease: is it worse and why? Proceedings of the American Thoracic Society 2011. PMID: 21653535


  127. Huang L, Cattamanchi A, Davis JL, den Boon S, Kovacs J, Meshnick S, Miller RF, Walzer PD, Worodria W, Masur H. HIV-associated Pneumocystis pneumonia. Volume 8 of Issue 3. Proceedings of the American Thoracic Society 2011. PMID: 21653531


  128. Crothers K, Thompson BW, Burkhardt K, Morris A, Flores SC, Diaz PT, Chaisson RE, Kirk GD, Rom WN, Huang L. HIV-associated lung infections and complications in the era of combination antiretroviral therapy. Proceedings of the American Thoracic Society 2011. PMID: 21653528


  129. Dhanireddy S, Harrington RD, Crane HM, Gingo MR, Morris A, Huang L, Crothers K. Pandemic (H1N1) 2009 and HIV Infection. Emerging infectious diseases 2011. PMID: 21749797


  130. Almodovar S, Hsue PY, Morelli J, Huang L, Flores SC. Pathogenesis of HIV-associated pulmonary hypertension: potential role of HIV-1 Nef. Proceedings of the American Thoracic Society 2011. PMID: 21653533


  131. Boehme CC, Nicol MP, Nabeta P, Michael JS, Gotuzzo E, Tahirli R, Gler MT, Blakemore R, Worodria W, Gray C, Huang L, Caceres T, Mehdiyev R, Raymond L, Whitelaw A, Sagadevan K, Alexander H, Albert H, Cobelens F, Cox H, Alland D, Perkins MD. Feasibility, diagnostic accuracy, and effectiveness of decentralised use of the Xpert MTB/RIF test for diagnosis of tuberculosis and multidrug resistance: a multicentre implementation study. Lancet (London, England) 2011. PMID: 21507477


  132. Davis J, Katamba A, Vasquez J, Crawford E, Sserwanga A, Kakeeto S, Kizito F, Dorsey G, den Boon S, Vittinghoff E, Huang L, Adatu F, Kamya MR, Hopewell PC, Cattamanchi A. Evaluating tuberculosis case detection via real-time monitoring of tuberculosis diagnostic services. Volume 184 of Issue 3. American journal of respiratory and critical care medicine 2011. PMID: 21471088


  133. Morris A, Crothers K, Beck JM, Huang L. An official ATS workshop report: Emerging issues and current controversies in HIV-associated pulmonary diseases. Proceedings of the American Thoracic Society 2011. PMID: 21364216


  134. Cattamanchi A, Smith R, Steingart KR, Metcalfe JZ, Date A, Coleman C, Marston BJ, Huang L, Hopewell PC, Pai M. Interferon-gamma release assays for the diagnosis of latent tuberculosis infection in HIV-infected individuals: a systematic review and meta-analysis. Volume 56 of Issue 3. Journal of acquired immune deficiency syndromes (1999) 2011. PMID: 21239993


  135. Huang L. Clinical and translational research in pneumocystis and pneumocystis pneumonia. Parasite (Paris, France) 2011. PMID: 21395200


  136. Davis JL, Huang L, Worodria W, Masur H, Cattamanchi A, Huber C, Miller C, Conville PS, Murray P, Kovacs JA. Nucleic acid amplification tests for diagnosis of smear-negative TB in a high HIV-prevalence setting: a prospective cohort study. Volume 6 of Issue 1. PloS one 2011. PMID: 21298001


  137. Djawe K, Huang L, Daly KR, Levin L, Koch J, Schwartzman A, Fong S, Roth B, Subramanian A, Grieco K, Jarlsberg L, Walzer PD. Serum antibody levels to the Pneumocystis jirovecii major surface glycoprotein in the diagnosis of P. jirovecii pneumonia in HIV+ patients. PloS one 2010. PMID: 21151564


  138. Kyeyune R, den Boon S, Cattamanchi A, Davis JL, Worodria W, Yoo SD, Huang L. Causes of early mortality in HIV-infected TB suspects in an East African referral hospital. Volume 55 of Issue 4. Journal of acquired immune deficiency syndromes (1999) 2010. PMID: 21105258


  139. Crothers K, Huang L, Goulet JL, Goetz MB, Brown ST, Rodriguez-Barradas MC, Oursler KK, Rimland D, Gibert CL, Butt AA, Justice AC. HIV infection and risk for incident pulmonary diseases in the combination antiretroviral therapy era. American journal of respiratory and critical care medicine 2010. PMID: 20851926


  140. Cattamanchi A, Huang L, Worodria W, den Boon S, Kalema N, Katagira W, Byanyima P, Yoo S, Matovu J, Hopewell PC, Davis JL. Integrated strategies to optimize sputum smear microscopy: a prospective observational study. Volume 183 of Issue 4. American journal of respiratory and critical care medicine 2010. PMID: 20851925


  141. Worodria W, Davis JL, Cattamanchi A, Andama A, den Boon S, Yoo SD, Hopewell PC, Huang L. Bronchoscopy is useful for diagnosing smear-negative tuberculosis in HIV-infected patients. The European respiratory journal 2010. PMID: 20675782


  142. Deok-jong Yoo S, Worodria W, Davis JL, Cattamanchi A, den Boon S, Kyeyune R, Kisembo H, Huang L. The prevalence and clinical course of HIV-associated pulmonary cryptococcosis in Uganda. Volume 54 of Issue 3. Journal of acquired immune deficiency syndromes (1999) 2010. PMID: 20150818


  143. Everett CK, Fei MW, Huang L. Respiratory emergencies in HIV-infected persons. Emergency medicine clinics of North America 2010. PMID: 20413012


  144. Cattamanchi A, Davis JL, Pai M, Huang L, Hopewell PC, Steingart KR. Does bleach processing increase the accuracy of sputum smear microscopy for diagnosing pulmonary tuberculosis? Journal of clinical microbiology 2010. PMID: 20421442


  145. Davis JL, Worodria W, Kisembo H, Metcalfe JZ, Cattamanchi A, Kawooya M, Kyeyune R, den Boon S, Powell K, Okello R, Yoo S, Huang L. Clinical and radiographic factors do not accurately diagnose smear-negative tuberculosis in HIV-infected inpatients in Uganda: a cross-sectional study. Volume 5 of Issue 3. PloS one 2010. PMID: 20361038


  146. Cattamanchi A, Ssewenyana I, Davis JL, Huang L, Worodria W, den Boon S, Yoo S, Andama A, Hopewell PC, Cao H. Role of interferon-gamma release assays in the diagnosis of pulmonary tuberculosis in patients with advanced HIV infection. Volume 10. BMC infectious diseases 2010. PMID: 20302657


  147. Klatser P, Anthony R, den Hertog A, Leeflang M, Boer K. Misleading conclusion. 2010. PMID: 20132633


  148. Calderon EJ, Dei-Cas E. Pneumocystis infection: unraveling the colonization-to-disease shift. Expert review of anti-infective therapy 2010. PMID: 20192679


  149. Blount RJ,
    Huang L. Clinical approach to HIV-associated pulmonary disease Clin Pulm Med. 2010. PMID:


  150. Ripamonti C, Orenstein A, Kutty G, Huang L, Schuhegger R, Sing A, Fantoni G, Atzori C, Vinton C, Huber C, Conville PS, Kovacs JA. Restriction fragment length polymorphism typing demonstrates substantial diversity among Pneumocystis jirovecii isolates. The Journal of infectious diseases 2009. PMID: 19795979


  151. Fei MW, Kim EJ, Sant CA, Jarlsberg LG, Davis JL, Swartzman A, Huang L. Predicting mortality from HIV-associated Pneumocystis pneumonia at illness presentation: an observational cohort study. Thorax 2009. PMID: 19825785


  152. Tipirneni R, Daly KR, Jarlsberg LG, Koch JV, Swartzman A, Roth BM, Walzer PD, Huang L. Healthcare worker occupation and immune response to Pneumocystis jirovecii. Emerging infectious diseases 2009. PMID: 19861050


  153. Cattamanchi A, Davis JL, Worodria W, den Boon S, Yoo S, Matovu J, Kiidha J, Nankya F, Kyeyune R, Byanyima P, Andama A, Joloba M, Osmond DH, Hopewell PC, Huang L. Sensitivity and specificity of fluorescence microscopy for diagnosing pulmonary tuberculosis in a high HIV prevalence setting. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2009. PMID: 19723403


  154. Jagannathan P, Davis E, Jacobson M, Huang L. Life-threatening immune reconstitution inflammatory syndrome after Pneumocystis pneumonia: a cautionary case series. AIDS (London, England) 2009. PMID: 19684486


  155. Powell K, Huang L. The ART of caring for patients with HIV infection in the ICU. Intensive care medicine 2009. PMID: 19636534


  156. George MP, Kannass M, Huang L, Sciurba FC, Morris A. Respiratory symptoms and airway obstruction in HIV-infected subjects in the HAART era. PloS one 2009. PMID: 19621086


  157. Andama AO, Cattamanchi A, Davis JL, den Boon S, Worodria W, Huang L. Modified Giemsa method for confirmation of Pneumocystis pneumonia in low-income countries. Volume 2009. BMJ case reports 2009. PMID: 21691388


  158. Feldman MD, Huang L, Guglielmo BJ, Jordan R, Kahn J, Creasman JM, Wiener-Kronish JP, Lee KA, Tehrani A, Yaffe K, Brown JS. Training the next generation of research mentors: the University of California, San Francisco, Clinical & Translational Science Institute Mentor Development Program. Clinical and translational science 2009. PMID: 19774102


  159. Cattamanchi A, Dowdy DW, Davis JL, Worodria W, Yoo S, Joloba M, Matovu J, Hopewell PC, Huang L. Sensitivity of direct versus concentrated sputum smear microscopy in HIV-infected patients suspected of having pulmonary tuberculosis. Volume 9. BMC infectious diseases 2009. PMID: 19419537


  160. Huang L, Crothers K. HIV-associated opportunistic pneumonias. Respirology (Carlton, Vic.) 2009. PMID: 19645867


  161. Crothers K, Huang L. Pulmonary complications of immune reconstitution inflammatory syndromes in HIV-infected patients. Respirology (Carlton, Vic.) 2009. PMID: 19192228


  162. Crothers, K, Huang, L, and Morris, A.. Non-infectious pulmonary diseases in HIV 2009. PMID:


  163. Heffelfinger JD, Voetsch AC, Nakamura GV, Sullivan PS, McNaghten AD, Huang L. Nonadherence to primary prophylaxis against Pneumocystis jirovecii pneumonia. PloS one 2009. PMID: 19319199


  164. Shea YR, Davis JL, Huang L, Kovacs JA, Masur H, Mulindwa F, Opus S, Chow Y, Murray PR. High sensitivity and specificity of acid-fast microscopy for diagnosis of pulmonary tuberculosis in an African population with a high prevalence of human immunodeficiency virus. Journal of clinical microbiology 2009. PMID: 19297594


  165. Davis JL, Huang L, Kovacs JA, Masur H, Murray P, Havlir DV, Worodria WO, Charlebois ED, Srikantiah P, Cattamanchi A, Huber C, Shea YR, Chow Y, Fischer SH. Polymerase chain reaction of secA1 on sputum or oral wash samples for the diagnosis of pulmonary tuberculosis. Volume 48 of Issue 6. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2009. PMID: 19207077


  166. Chakravorty S, Tyagi JS, Cattamanchi A, Davis JL, Worodria W, Yoo S, Huang L. Performance of modified universal sample processing method in a field study in Uganda. Volume 47 of Issue 2. Journal of clinical microbiology 2009. PMID: 19189927


  167. Fei MW, Sant CA, Kim EJ, Swartzman A, Davis JL, Jarlsberg LG, Huang L. Severity and outcomes of Pneumocystis pneumonia in patients newly diagnosed with HIV infection: an observational cohort study. Scandinavian journal of infectious diseases 2009. PMID: 19521925


  168. Powell K, Davis JL, Morris AM, Chi A, Bensley MR, Huang L. Survival for patients With HIV admitted to the ICU continues to improve in the current era of combination antiretroviral therapy. Chest 2008. PMID: 18719058


  169. Cattamanchi A, Davis JL, Worodria W, Yoo S, Matovu J, Kiidha J, Nankya F, Kyeyune R, Andama A, Joloba M, Osmond D, Hopewell P, Huang L. Poor performance of universal sample processing method for diagnosis of pulmonary tuberculosis by smear microscopy and culture in Uganda. Volume 46 of Issue 10. Journal of clinical microbiology 2008. PMID: 18701657


  170. Wang P, Huang L, Davis JL, Swartzman A, Roth B, Stone J, Wu AH. A hydrophilic-interaction chromatography tandem mass spectrometry method for quantitation of serum s-adenosylmethionine in patients infected with human immunodeficiency virus. Clinica chimica acta; international journal of clinical chemistry 2008. PMID: 18619430


  171. Davis JL, Morris A, Kallet RH, Powell K, Chi AS, Bensley M, Luce JM, Huang L. Low tidal volume ventilation is associated with reduced mortality in HIV-infected patients with acute lung injury. Thorax 2008. PMID: 18535118


  172. Hsue PY, Deeks SG, Farah HH, Palav S, Ahmed SY, Schnell A, Ellman AB, Huang L, Dollard SC, Martin JN. Role of HIV and human herpesvirus-8 infection in pulmonary arterial hypertension. AIDS (London, England) 2008. PMID: 18427200


  173. Davis JL, Fei M, Huang L. Respiratory infection complicating HIV infection. Current opinion in infectious diseases 2008. PMID: 18317044


  174. Morris A, Wei K, Afshar K, Huang L. Epidemiology and clinical significance of pneumocystis colonization. The Journal of infectious diseases 2008. PMID: 18171279


  175. Fei, M
    Huang, L. HIV-associated pneumonias BETA 2008. PMID:


  176. Davis JL, Welsh DA, Beard CB, Jones JL, Lawrence GG, Fox MR, Crothers K, Morris A, Charbonnet D, Swartzman A, Huang L. Pneumocystis colonisation is common among hospitalised HIV infected patients with non-Pneumocystis pneumonia. Thorax 2007. PMID: 18024536


  177. Davis JL, Shum AK, Huang L. A 36-year-old man with AIDS and relapsing, nonproductive cough. Volume 131 of Issue 6. Chest 2007. PMID: 17565026


  178. Huang L, Morris A, Limper AH, Beck JM. An Official ATS Workshop Summary: Recent advances and future directions in pneumocystis pneumonia (PCP). Proceedings of the American Thoracic Society 2006. PMID: 17065370


  179. de Oliveira A, Unnasch TR, Crothers K, Eiser S, Zucchi P, Moir J, Beard CB, Lawrence GG, Huang L. Performance of a molecular viability assay for the diagnosis of Pneumocystis pneumonia in HIV-infected patients. Diagnostic microbiology and infectious disease 2006. PMID: 17049800


  180. Saccente M. Intensive care of patients with HIV infection. The New England journal of medicine 2006. PMID: 17035660


  181. Daly KR, Huang L, Morris A, Koch J, Crothers K, Levin L, Eiser S, Satwah S, Zucchi P, Walzer PD. Antibody response to Pneumocystis jirovecii major surface glycoprotein. Emerging infectious diseases 2006. PMID: 16965702


  182. Huang L, Quartin A, Jones D, Havlir DV. Intensive care of patients with HIV infection. The New England journal of medicine 2006. PMID: 16837681


  183. Miller RF, Huang L. A need for standardized definitions for clinical studies of Pneumocystis. The Journal of eukaryotic microbiology 2006. PMID: 17169079


  184. Morris A, Masur H, Huang L. Current issues in critical care of the human immunodeficiency virus-infected patient. Critical care medicine 2006. PMID: 16374154


  185. Huang L, Welsh DA, Miller RF, Beard CB, Lawrence GG, Fox M, Swartzman A, Bensley MR, Carbonnet D, Davis JL, Chi A, Yoo BJ, Jones JL. Pneumocystis jirovecii dihydropteroate synthase gene mutations and human immunodeficiency virus-associated Pneumocystis pneumonia. The Journal of eukaryotic microbiology 2006. PMID: 17169022


  186. Huang L, Murray JF. A rose is a rose: but what about Pneumocystis pneumonia? The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2005. PMID: 16466049


  187. Beard CB, Fox MR, Lawrence GG, Guarner J, Hanzlick RL, Huang L, del Rio C, Rimland D, Duchin JS, Colley DG. Genetic differences in Pneumocystis isolates recovered from immunocompetent infants and from adults with AIDS: Epidemiological Implications. The Journal of infectious diseases 2005. PMID: 16235182


  188. Crothers K, Beard CB, Turner J, Groner G, Fox M, Morris A, Eiser S, Huang L. Severity and outcome of HIV-associated Pneumocystis pneumonia containing Pneumocystis jirovecii dihydropteroate synthase gene mutations. AIDS (London, England) 2005. PMID: 15867494


  189. Morris A, Lundgren JD, Masur H, Walzer PD, Hanson DL, Frederick T, Huang L, Beard CB, Kaplan JE. Current epidemiology of Pneumocystis pneumonia. Emerging infectious diseases 2004. PMID: 15504255


  190. Huang L, Crothers K, Atzori C, Benfield T, Miller R, Rabodonirina M, Helweg-Larsen J. Dihydropteroate synthase gene mutations in Pneumocystis and sulfa resistance. Emerging infectious diseases 2004. PMID: 15504256


  191. Innes AL, Huang L, Nishimura SL. Resolution of lymphocytic interstitial pneumonitis in an HIV infected adult after treatment with HAART. Sexually transmitted infections 2004. PMID: 15459417


  192. Miller R, Huang L. Pneumocystis jirovecii infection. Thorax 2004. PMID: 15333844


  193. Morris A, Sciurba FC, Lebedeva IP, Githaiga A, Elliott WM, Hogg JC, Huang L, Norris KA. Association of chronic obstructive pulmonary disease severity and Pneumocystis colonization. American journal of respiratory and critical care medicine 2004. PMID: 15117741


  194. Larsen HH, Huang L, Kovacs JA, Crothers K, Silcott VA, Morris A, Turner JR, Beard CB, Masur H, Fischer SH. A prospective, blinded study of quantitative touch-down polymerase chain reaction using oral-wash samples for diagnosis of Pneumocystis pneumonia in HIV-infected patients. The Journal of infectious diseases 2004. PMID: 15116305


  195. Morris DG, Jasmer RM, Huang L, Gotway MB, Nishimura S, King TE. Sarcoidosis following HIV infection: evidence for CD4+ lymphocyte dependence. Volume 124 of Issue 3. Chest 2003. PMID: 12970019


  196. Lin X, Irwin D, Kanazawa S, Huang L, Romeo J, Yen TS, Peterlin BM. Transcriptional profiles of latent human immunodeficiency virus in infected individuals: effects of Tat on the host and reservoir. Journal of virology 2003. PMID: 12857891


  197. Morris A, Wachter RM, Luce J, Turner J, Huang L. Improved survival with highly active antiretroviral therapy in HIV-infected patients with severe Pneumocystis carinii pneumonia. AIDS (London, England) 2003. PMID: 12478071


  198. Huang L, Crothers K, DeOliveira A, Eiser S, Zucchi P, Beard CB, Unnasch TR. Application of an mRNA-based molecular viability assay to oropharyngeal washes for the diagnosis of Pneumocystis pneumonia in HIV-infected patients. A pilot study. The Journal of eukaryotic microbiology 2003. PMID: 14736185


  199. Huang L, Crothers K, Morris A, Groner G, Fox M, Turner JR, Merrifield C, Eiser S, Zucchi P, Beard CB. Pneumocystis colonization in HIV-infected patients. The Journal of eukaryotic microbiology 2003. PMID: 14736184


  200. Crothers K, Huang L, Morris A, Fox M, Groner G, Turner JR, Merrifield C, Eiser S, Friedly J, Gravari E, Zucchi P, Beard CB. Pneumocystis dihydropteroate synthase mutations in patients with Pneumocystis pneumonia who are newly diagnosed with HIV infection. The Journal of eukaryotic microbiology 2003. PMID: 14736181


  201. Ma L, Kutty G, Jia Q, Imamichi H, Huang L, Atzori C, Beckers P, Groner G, Beard CB, Kovacs JA. Analysis of variation in tandem repeats in the intron of the major surface glycoprotein expression site of the human form of Pneumocystis carinii. The Journal of infectious diseases 2002. PMID: 12447742


  202. Jasmer RM, Gotway MB, Creasman JM, Webb WR, Edinburgh KJ, Huang L. Clinical and radiographic predictors of the etiology of computed tomography-diagnosed intrathoracic lymphadenopathy in HIV-infected patients. Journal of acquired immune deficiency syndromes (1999) 2002. PMID: 12439204


  203. Morris A, Creasman J, Turner J, Luce JM, Wachter RM, Huang L. Intensive care of human immunodeficiency virus-infected patients during the era of highly active antiretroviral therapy. American journal of respiratory and critical care medicine 2002. PMID: 12153955


  204. Nimri LF, Moura IN, Huang L, del Rio C, Rimland D, Duchin JS, Dotson EM, Beard CB. Genetic diversity of Pneumocystis carinii f. sp. hominis based on variations in nucleotide sequences of internal transcribed spacers of rRNA genes. Journal of clinical microbiology 2002. PMID: 11923323


  205. Morris A, Beard CB, Huang L. Update on the epidemiology and transmission of Pneumocystis carinii. Microbes and infection 2002. PMID: 11825780


  206. Beck JM, Rosen MJ, Peavy HH. Pulmonary complications of HIV infection. Report of the Fourth NHLBI Workshop. American journal of respiratory and critical care medicine 2001. PMID: 11739145


  207. Navin TR, Beard CB, Huang L, del Rio C, Lee S, Pieniazek NJ, Carter JL, Le T, Hightower A, Rimland D. Effect of mutations in Pneumocystis carinii dihydropteroate synthase gene on outcome of P carinii pneumonia in patients with HIV-1: a prospective study. Lancet (London, England) 2001. PMID: 11520525


  208. Soumelis V, Scott I, Gheyas F, Bouhour D, Cozon G, Cotte L, Huang L, Levy JA, Liu YJ. Depletion of circulating natural type 1 interferon-producing cells in HIV-infected AIDS patients. Blood 2001. PMID: 11493432


  209. Kazanjian P, Armstrong W, Hossler PA, Lee CH, Huang L, Beard CB, Carter J, Crane L, Duchin J, Burman W, Richardson J, Meshnick SR. Pneumocystis carinii cytochrome b mutations are associated with atovaquone exposure in patients with AIDS. The Journal of infectious diseases 2001. PMID: 11181161


  210. Meshnick SR, Hossler PA, Enger KS, Kazanjian P, Rest JS, Mindell D, Li B, Lee CH, Nimri LF, Carter JL, Beard CB, Huang L. Distribution of DHPS mutations among ITS subtypes of P. carinii f. sp. hominis. The Journal of eukaryotic microbiology 2001. PMID: 11906022


  211. Huang L, Friedly J, Morris AM, Carter JL, Turner JR, Merrifield C, Navin TR, Beard CB. Pneumocystis carinii dihydropteroate synthase genotypes in HIV-infected persons residing in San Francisco: possible implications for disease transmission. The Journal of eukaryotic microbiology 2001. PMID: 11906028


  212. Huang L, Hecht FM. Why does Pneumocystis carinii pneumonia still occur? AIDS (London, England) 2000. PMID: 11101076


  213. Morris AM, Swanson M, Ha H, Huang L. Geographic distribution of human immunodeficiency virus-associated Pneumocystis carinii pneumonia in San Francisco. American journal of respiratory and critical care medicine 2000. PMID: 11069786


  214. Huang L, Beard CB, Creasman J, Levy D, Duchin JS, Lee S, Pieniazek N, Carter JL, del Rio C, Rimland D, Navin TR. Sulfa or sulfone prophylaxis and geographic region predict mutations in the Pneumocystis carinii dihydropteroate synthase gene. The Journal of infectious diseases 2000. PMID: 10979917


  215. Morris AM, Huang L, Bacchetti P, Turner J, Hopewell PC, Wallace JM, Kvale PA, Rosen MJ, Glassroth J, Reichman LB, Stansell JD. Permanent declines in pulmonary function following pneumonia in human immunodeficiency virus-infected persons. The Pulmonary Complications of HIV Infection Study Group. American journal of respiratory and critical care medicine 2000. PMID: 10934095


  216. Beard CB, Carter JL, Keely SP, Huang L, Pieniazek NJ, Moura IN, Roberts JM, Hightower AW, Bens MS, Freeman AR, Lee S, Stringer JR, Duchin JS, del Rio C, Rimland D, Baughman RP, Levy DA, Dietz VJ, Simon P, Navin TR. Genetic variation in Pneumocystis carinii isolates from different geographic regions: implications for transmission. Emerging infectious diseases 2000. PMID: 10827116


  217. Jasmer RM, Edinburgh KJ, Thompson A, Gotway MB, Creasman JM, Webb WR, Huang L. Clinical and radiographic predictors of the etiology of pulmonary nodules in HIV-infected patients. Chest 2000. PMID: 10767234


  218. Edinburgh KJ, Jasmer RM, Huang L, Reddy GP, Chung MH, Thompson A, Halvorsen RA, Webb RA. Multiple pulmonary nodules in AIDS: usefulness of CT in distinguishing among potential causes. Radiology 2000. PMID: 10671590


  219. Huang L, Stansell J, Osmond D, Turner J, Shafer KP, Fulkerson W, Kvale P, Wallace J, Rosen M, Glassroth J, Reichman L, Hopewell P. Performance of an algorithm to detect Pneumocystis carinii pneumonia in symptomatic HIV-infected persons. Pulmonary Complications of HIV Infection Study Group. Chest 1999. PMID: 10208204


  220. Horton CK, Huang L, Goozé L. Pseudallescheria boydii infection in AIDS. Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1999. PMID: 10048912


  221. Huang, L.. Definitive diagnosis or empiric therapy of Pneumocystis carinii pneumonia Pulmonary Infections Forum 1999. PMID:


  222. Holtzer CD, Jacobson MA, Hadley WK, Huang L, Stanley HD, Montanti R, Wong MK, Stansell JD. Decline in the rate of specific opportunistic infections at San Francisco General Hospital, 1994-1997. AIDS (London, England) 1998. PMID: 9792398


  223. Gruden JF, Huang L, Turner J, Webb WR, Merrifield C, Stansell JD, Gamsu G, Hopewell PC. High-resolution CT in the evaluation of clinically suspected Pneumocystis carinii pneumonia in AIDS patients with normal, equivocal, or nonspecific radiographic findings. AJR. American journal of roentgenology 1997. PMID: 9308446


  224. Jasmer, R
    Huang, L. TB or not TB AIDS care 1997. PMID:


  225. Huang L, Stansell JD. AIDS and the lung. The Medical clinics of North America 1996. PMID: 8676614


  226. Huang L, Schnapp LM, Gruden JF, Hopewell PC, Stansell JD. Presentation of AIDS-related pulmonary Kaposi's sarcoma diagnosed by bronchoscopy. American journal of respiratory and critical care medicine 1996. PMID: 8616570


  227. Huang L, Hecht FM, Stansell JD, Montanti R, Hadley WK, Hopewell PC. Suspected Pneumocystis carinii pneumonia with a negative induced sputum examination. Is early bronchoscopy useful? American journal of respiratory and critical care medicine 1995. PMID: 7767533


  228. Gruden JF, Huang L, Webb WR, Gamsu G, Hopewell PC, Sides DM. AIDS-related Kaposi sarcoma of the lung: radiographic findings and staging system with bronchoscopic correlation. Radiology 1995. PMID: 7724781