Jesse Ikeme, MD

HS Asst Clinical Professor

Jesse Ikeme is a nephrologist and Assistant Professor in the Division of Nephrology at UCSF. His research aims to improve the understanding and management of chronic kidney disease (CKD) with a particular focus on cardiovascular risk. His work integrates clinical epidemiology, novel biomarkers, and health services research to enhance early detection and treatment strategies for CKD.

Education
MAS, 2024 - Clinical Research, UCSF
Fellowship, 2024 - Nephrology, UCSF
Residency, 2021 - Internal Medicine, UCSF
MD, 2018 - Medicine, UCSF School of Medicine
BS, 2013 - Biology, Stanford University
Publications
  1. Ikeme JC, Scherzer R, Garimella PS, Hallan SI, Katz R, Estrella MM, Ix JH, Shlipak MG. Associations of Plasma and Urine Uromodulin With Kidney Disease Progression in Persons With Chronic Kidney Disease and Hypertension: The Systolic Blood Pressure Intervention Trial. Kidney Medicine 2025. PMID: 41209167


  2. Ikeme J, Madden E, Lamprea-Montealegre JA, Chu CD, Shlipak MG, McCoy IE, Estrella MM. Association of kidney function with SGLT2 inhibitor discontinuation among United States Veterans. Clinical journal of the American Society of Nephrology : CJASN 2024. PMID: 39167449


  3. Ikeme JC, Scherzer R, Garimella PS, Hallan SI, Katz R, Estrella MM, Ix JH, Shlipak MG. The Association of Plasma and Urine Uromodulin With Cardiovascular Disease in Persons With Hypertension and CKD. American journal of kidney diseases : the official journal of the National Kidney Foundation 2024. PMID: 39033957


  4. Ikeme JC, Newman TB, Kohn MA. Arginine or Hypertonic Saline-Stimulated Copeptin to Diagnose AVP Deficiency. Volume 390 of Issue 3. The New England journal of medicine 2024. PMID: 38231638


  5. Ikeme JC, Katz R, Muiru AN, Estrella MM, Scherzer R, Garimella PS, Hallan SI, Peralta CA, Ix JH, Shlipak MG. Clinical Risk Factors For Kidney Tubule Biomarker Abnormalities Among Hypertensive Adults With Reduced eGFR in the SPRINT Trial. American journal of hypertension 2022. PMID: 36094158


  6. Ikeme JC, Salazar JW, Grant RW. Reappraising Medical Syntax-Does Race Belong in the First Line of the Patient History? Volume 181 of Issue 3. JAMA internal medicine 2021. PMID: 33427865


  7. Ikeme JC, Pergola PE, Scherzer R, Shlipak MG, Catanese L, McClure LA, Benavente OR, Peralta CA. Cerebral White Matter Hyperintensities, Kidney Function Decline, and Recurrent Stroke After Intensive Blood Pressure Lowering: Results From the Secondary Prevention of Small Subcortical Strokes ( SPS 3) Trial. Journal of the American Heart Association 2019. PMID: 30686103


  8. Ikeme JC, Pergola PE, Scherzer R, Shlipak MG, Benavente OR, Peralta CA. Post Hoc Analyses of Randomized Clinical Trial for the Effect of Clopidogrel Added to Aspirin on Kidney Function. Clinical journal of the American Society of Nephrology : CJASN 2017. PMID: 28446537


  9. Muindi F, Colas D, Ikeme J, Ruby NF, Heller HC. Loss of Melanopsin Photoreception and Antagonism of the Histamine H3 Receptor by Ciproxifan Inhibit Light-Induced Sleep in Mice. Volume 10 of Issue 6. PloS one 2015. PMID: 26083020