James Ryan, MD

Professor

VA Medicine Home

Education
Post-Doc Fellow/Scholar, 1991 - Medicine, University of California, San Francisco
Residency, - , University of California, San Francisco
Publications

  1. Wallace AW, Cirillo PM, Ryan JC, Krigbaum NY, Badathala A, Cohn BA. Association of the patterns of use of medications with mortality of COVID-19 infection: a hospital-based observational study. TO REMOVE 2021. PMID: 34972763


  2. Martin CW, Ryan JC, Bullock TS, Cabot JH, Makhani AA, Griffin LP, Zelle BA. Surgical site complications in open pronation-abduction ankle fracture-dislocations with medial tension failure wounds. Journal of orthopaedic trauma 2021. PMID: 33771964


  3. Zelle BA, Johnson TR, Ryan JC, Martin CW, Cabot JH, Griffin LP, Bullock TS, Ahmad F, Brady CI, Shah K. Fate of the Uninsured Ankle Fracture: Significant Delays in Treatment Result in an Increased Risk of Surgical Site Infection. Volume 35 of Issue 3. Journal of orthopaedic trauma 2021. PMID: 32947353


  4. Prabhakar G, Bullock TS, Martin CW, Ryan JC, Cabot JH, Makhani AA, Griffin LP, Shah K, Zelle BA. Skin closure with surgical staples in ankle fractures: a safe and reliable method. Volume 45 of Issue 1. International orthopaedics 2020. PMID: 32951119


  5. Fernandes S, Srivastava N, Sudan R, Middleton FA, Shergill AK, Ryan JC, Kerr WG. SHIP1 Deficiency in Inflammatory Bowel Disease Is Associated With Severe Crohn's Disease and Peripheral T Cell Reduction. Volume 9. Frontiers in immunology 2018. PMID: 29872435


  6. Dai KZ, Ryan JC, Naper C, Vaage JT. Identification of MHC Class Ib Ligands for Stimulatory and Inhibitory Ly49 Receptors and Induction of Potent NK Cell Alloresponses in Rats. Volume 200 of Issue 8. Journal of immunology (Baltimore, Md. : 1950) 2018. PMID: 29531166


  7. Méndez-Lagares G, Lu D, Chen C, Terrault N, Segal MR, Khalili M, Monto A, Shen H, Manos MM, Lanier LL, Ryan JC, McCune JM, Hartigan-O'Connor DJ. Memory T Cell Proliferation before Hepatitis C Virus Therapy Predicts Antiviral Immune Responses and Treatment Success. Volume 200 of Issue 3. Journal of immunology (Baltimore, Md. : 1950) 2017. PMID: 29263212


  8. Vadstrup K, Galsgaard ED, Jensen H, Lanier LL, Ryan JC, Chen SY, Nolan GP, Vester-Andersen MK, Pedersen JS, Gerwien J, Jensen T, Bendtsen F. NKG2D ligand expression in Crohn's disease and NKG2D-dependent stimulation of CD8+ T cell migration. Volume 103 of Issue 1. Experimental and molecular pathology 2017. PMID: 28684217


  9. Sandra Fernandes Denney, Neetu Srivastava, Frank Middleton, James Ryan, William Kerr. P-305 SHIP1 Deficiency in Adult Inflammatory Bowel Disease Is Associated with Severe Crohn's Disease and Peripheral T Cell Reduction. Inflammatory bowel diseases 2017. PMID:


  10. Zhang Y, Davis C, Shah S, Hughes D, Ryan JC, Altomare D, Peña MM. IL-33 promotes growth and liver metastasis of colorectal cancer in mice by remodeling the tumor microenvironment and inducing angiogenesis. Volume 56 of Issue 1. Molecular carcinogenesis 2016. PMID: 27120577


  11. Cozen ML, Ryan JC, Shen H, Cheung R, Kaplan DE, Pocha C, Brau N, Aytaman A, Schmidt WN, Pedrosa M, Anand BS, Chang KM, Morgan T, Monto A. Improved Survival Among all Interferon-a-Treated Patients in HCV-002, a Veterans Affairs Hepatitis C Cohort of 2211 Patients, Despite Increased Cirrhosis Among Nonresponders. Volume 61 of Issue 6. Digestive diseases and sciences 2016. PMID: 27059981


  12. William Kerr, Sandra Fernandes, Frank Middleton, John Chisholm, James Ryan. P-176 SHIP1 Deficiency in Human IBD. Inflammatory bowel diseases 2016. PMID:


  13. Sandra Fernandes, James Ryan, Frank Middleton, John Chisholm, William Kerr. P-177 Altered SHIP1-Protein Degradation in a Subset of IBD Patients. Inflammatory bowel diseases 2016. PMID:


  14. Shergill AK, Conners EE, McQuaid KR, Epstein S, Ryan JC, Shah JN, Inadomi J, Somsouk M. Protective association of colonoscopy against proximal and distal colon cancer and patterns in interval cancer. Volume 82 of Issue 3. Gastrointestinal endoscopy 2015. PMID: 25936449


  15. Ryan JC, Wu Q, Shoemaker RC. Transcriptomic signatures in whole blood of patients who acquire a chronic inflammatory response syndrome (CIRS) following an exposure to the marine toxin ciguatoxin. Volume 8. BMC medical genomics 2015. PMID: 25889530


  16. Mancia A, Abelli L, Kucklick JR, Rowles TK, Wells RS, Balmer BC, Hohn AA, Baatz JE, Ryan JC. Microarray applications to understand the impact of exposure to environmental contaminants in wild dolphins (Tursiops truncatus). Volume 19. Marine genomics 2014. PMID: 25479946


  17. Shoemaker RC, House D, Ryan JC. Structural brain abnormalities in patients with inflammatory illness acquired following exposure to water-damaged buildings: a volumetric MRI study using NeuroQuant®. Volume 45. Neurotoxicology and teratology 2014. PMID: 24946038


  18. Mancia A, Ryan JC, Van Dolah FM, Kucklick JR, Rowles TK, Wells RS, Rosel PE, Hohn AA, Schwacke LH. Machine learning approaches to investigate the impact of PCBs on the transcriptome of the common bottlenose dolphin (Tursiops truncatus). Volume 100. Marine environmental research 2014. PMID: 24695049


  19. Ho EY, Cozen ML, Shen H, Lerrigo R, Trimble E, Ryan JC, Corvera CU, Monto A. Expanded use of aggressive therapies improves survival in early and intermediate hepatocellular carcinoma. Volume 16 of Issue 8. HPB : the official journal of the International Hepato Pancreato Biliary Association 2014. PMID: 24467780


  20. Hartigan-O'Connor DJ, Lin D, Ryan JC, Shvachko VA, Cozen ML, Segal MR, Terrault NA, Lanier LL, Manos MM, McCune JM. Monocyte activation by interferon a is associated with failure to achieve a sustained virologic response after treatment for hepatitis C virus infection. The Journal of infectious diseases 2013. PMID: 24325966


  21. Sandra Fernandes, James Ryan, William Kerr. O-018 SHIP1-deficiency in a Subset of IBD Patients. Inflammatory bowel diseases 2013. PMID:


  22. Rathburn CK, Sharp NJ, Ryan JC, Neely MG, Cook M, Chapman RW, Burnett LE, Burnett KG. Transcriptomic responses of juvenile Pacific whiteleg shrimp, Litopenaeus vannamei, to hypoxia and hypercapnic hypoxia. Volume 45 of Issue 17. Physiological genomics 2013. PMID: 23821614


  23. Cozen ML, Ryan JC, Shen H, Lerrigo R, Yee RM, Sheen E, Wu R, Monto A. Nonresponse to interferon-a based treatment for chronic hepatitis C infection is associated with increased hazard of cirrhosis. Volume 8 of Issue 4. PloS one 2013. PMID: 23637856


  24. Yee RM, Lehil MS, Rongey C, Shen H, Cozen ML, Monto A, Ryan JC. Impaired lymphocyte reactivity measured by immune function testing in untransplanted patients with cirrhosis. Volume 20 of Issue 4. Clinical and vaccine immunology : CVI 2013. PMID: 23389930


  25. Mancia A, Ryan JC, Chapman RW, Wu Q, Warr GW, Gulland FM, Van Dolah FM. Health status, infection and disease in California sea lions (Zalophus californianus) studied using a canine microarray platform and machine-learning approaches. Volume 36 of Issue 4. Developmental and comparative immunology 2011. PMID: 22067742


  26. Johnson JG, Morey JS, Neely MG, Ryan JC, Van Dolah FM. Transcriptome remodeling associated with chronological aging in the dinoflagellate, Karenia brevis. Volume 5. Marine genomics 2011. PMID: 22325718


  27. Ryan JC. Development of a measure of work motivation for a meta-theory of motivation. Volume 108 of Issue 3. Psychological reports 2011. PMID: 21879620


  28. Shegarfi H, Dai KZ, Daws MR, Ryan JC, Vaage JT, Rolstad B, Naper C. The rat NK cell receptors Ly49s4 and Ly49i4 recognize nonclassical MHC-I molecules on Listeria monocytogenes-infected macrophages. Volume 89 of Issue 4. Journal of leukocyte biology 2011. PMID: 21248147


  29. Shegarfi H, Dai KZ, Inngjerdingen M, Ryan JC, Vaage JT, Rolstad B, Naper C. The activating rat Ly49s5 receptor responds to increased levels of MHC class Ib molecules on Listeria monocytogenes-infected enteric epithelial cells. Volume 40 of Issue 12. European journal of immunology 2010. PMID: 21108473


  30. Ryan JC, Cross CA, Van Dolah FM. Effects of COX inhibitors on neurodegeneration and survival in mice exposed to the marine neurotoxin domoic acid. Volume 487 of Issue 1. Neuroscience letters 2010. PMID: 20934488


  31. Ryan JC, Morey JS, Bottein MY, Ramsdell JS, Van Dolah FM. Gene expression profiling in brain of mice exposed to the marine neurotoxin ciguatoxin reveals an acute anti-inflammatory, neuroprotective response. Volume 11. BMC neuroscience 2010. PMID: 20796285


  32. Shoemaker RC, House D, Ryan JC. Defining the neurotoxin derived illness chronic ciguatera using markers of chronic systemic inflammatory disturbances: a case/control study. Volume 32 of Issue 6. Neurotoxicology and teratology 2010. PMID: 20685390


  33. Li L, Fang CJ, Ryan JC, Niemi EC, Lebrón JA, Björkman PJ, Arase H, Torti FM, Torti SV, Nakamura MC, Seaman WE. Binding and uptake of H-ferritin are mediated by human transferrin receptor-1. Volume 107 of Issue 8. Proceedings of the National Academy of Sciences of the United States of America 2010. PMID: 20133674


  34. Amandeep K. Shergill, Krishna R. Asundi, Alan Barr, Janak N. Shah, James C. Ryan, Kenneth R. McQuaid, David Rempel. Response. Gastrointestinal endoscopy 2009. PMID:


  35. Shergill AK, Asundi KR, Barr A, Shah JN, Ryan JC, McQuaid KR, Rempel D. Pinch force and forearm-muscle load during routine colonoscopy: a pilot study. Volume 69 of Issue 1. Gastrointestinal endoscopy 2009. PMID: 19111694


  36. Maher JJ, Leon P, Ryan JC. Beyond insulin resistance: Innate immunity in nonalcoholic steatohepatitis. Volume 48 of Issue 2. Hepatology (Baltimore, Md.) 2008. PMID: 18666225


  37. Sue L. Currie, James C. Ryan, Daniel Tracy, Teresa L. Wright, Sally George, Rosemary McQuaid, Michael Kim, Hui Shen, Alexander Monto. Corrigendum to “A prospective study to examine persistent HCV reinfection in injection drug users who have previously cleared the virus” [Drug Alcohol Depend. 93(1–2) (2008) 148–154]. Drug and alcohol dependence 2008. PMID:


  38. Joseph Chen, Amandeep K. Shergill, Kenneth R. Mcquaid, James C. Ryan, Janak N. Shah. Endoscopic Evaluation and Management of Colonic Postpolypectomy Hemorrhage. Gastrointestinal endoscopy 2008. PMID:


  39. Morey JS, Ryan JC, Bottein Dechraoui MY, Rezvani AH, Levin ED, Gordon CJ, Ramsdell JS, Van Dolah FM. Liver genomic responses to ciguatoxin: evidence for activation of phase I and phase II detoxification pathways following an acute hypothermic response in mice. Volume 103 of Issue 2. Toxicological sciences : an official journal of the Society of Toxicology 2008. PMID: 18353800


  40. Twiner MJ, Ryan JC, Morey JS, Smith KJ, Hammad SM, Van Dolah FM, Hess P, McMahon T, Satake M, Yasumoto T, Doucette GJ. Transcriptional profiling and inhibition of cholesterol biosynthesis in human T lymphocyte cells by the marine toxin azaspiracid. Volume 91 of Issue 3. Genomics 2008. PMID: 18191373


  41. Currie SL, Ryan JC, Tracy D, Wright TL, George S, McQuaid R, Kim M, Shen H, Monto A. A prospective study to examine persistent HCV reinfection in injection drug users who have previously cleared the virus. Volume 93 of Issue 1-2. Drug and alcohol dependence 2007. PMID: 17977668


  42. Ryan JC, Bottein Dechraoui MY, Morey JS, Rezvani A, Levin ED, Gordon CJ, Ramsdell JS, Van Dolah FM. Transcriptional profiling of whole blood and serum protein analysis of mice exposed to the neurotoxin Pacific Ciguatoxin-1. Volume 28 of Issue 6. Neurotoxicology 2007. PMID: 17868886


  43. Amandeep K. Shergill, Krishna R. Asundi, Alan Barr, Janak N. Shah, James C. Ryan, Kenneth R. Mcquaid, David Rempel. Evaluation of Distal Upper Extremity Musculoskeletal Load During Routine Colonoscopy. Gastrointestinal endoscopy 2007. PMID:


  44. Amandeep K. Shergill, Arnel Deleon, James C. Ryan, Kenneth R. Mcquaid, Janak N. Shah. Prospective Randomized Trial of Standard Versus Magnetic Endoscope Imaging Colonoscopes On Patient Tolerance of Unsedated Colonoscopy. Gastrointestinal endoscopy 2007. PMID:


  45. Morey JS, Ryan JC, Van Dolah FM. Microarray validation: factors influencing correlation between oligonucleotide microarrays and real-time PCR. Volume 8. Biological procedures online 2006. PMID: 17242735


  46. Kveberg L, Dai KZ, Dissen E, Ryan JC, Rolstad B, Vaage JT, Naper C. Strain-dependent expression of four structurally related rat Ly49 receptors; correlation with NK gene complex haplotype and NK alloreactivity. Volume 58 of Issue 11. Immunogenetics 2006. PMID: 17028855


  47. Kveberg L, Bäck CJ, Dai KZ, Inngjerdingen M, Rolstad B, Ryan JC, Vaage JT, Naper C. The novel inhibitory NKR-P1C receptor and Ly49s3 identify two complementary, functionally distinct NK cell subsets in rats. Volume 176 of Issue 7. Journal of immunology (Baltimore, Md. : 1950) 2006. PMID: 16547249


  48. Ryan JC, Morey JS, Ramsdell JS, Van Dolah FM. Acute phase gene expression in mice exposed to the marine neurotoxin domoic acid. Volume 136 of Issue 4. Neuroscience 2005. PMID: 16216424


  49. Lidie KB, Ryan JC, Barbier M, Van Dolah FM. Gene expression in Florida red tide dinoflagellate Karenia brevis: analysis of an expressed sequence tag library and development of DNA microarray. Volume 7 of Issue 5. Marine biotechnology (New York, N.Y.) 2005. PMID: 15976935


  50. Kveberg L, Ryan JC, Rolstad B, Inngjerdingen M. Expression of regulator of G protein signalling proteins in natural killer cells, and their modulation by Ly49A and Ly49D. Volume 115 of Issue 3. Immunology 2005. PMID: 15946253


  51. Naper C, Dai KZ, Kveberg L, Rolstad B, Niemi EC, Vaage JT, Ryan JC. Two structurally related rat Ly49 receptors with opposing functions (Ly49 stimulatory receptor 5 and Ly49 inhibitory receptor 5) recognize nonclassical MHC class Ib-encoded target ligands. Volume 174 of Issue 5. Journal of immunology (Baltimore, Md. : 1950) 2005. PMID: 15728478


  52. Saether PC, Westgaard IH, Flornes LM, Hoelsbrekken SE, Ryan JC, Fossum S, Dissen E. Molecular cloning of KLRI1 and KLRI2, a novel pair of lectin-like natural killer-cell receptors with opposing signalling motifs. Volume 56 of Issue 11. Immunogenetics 2005. PMID: 15650876


  53. Nylenna O, Flornes LM, Westgaard IH, Woon PY, Naper C, Vaage JT, Gauguier D, Ryan JC, Dissen E, Fossum S. Killer cell lectin-like receptors and the natural killer cell gene complex. Volume 564. Advances in experimental medicine and biology 2005. PMID: 16400803


  54. Nylenna O, Naper C, Vaage JT, Woon PY, Gauguier D, Dissen E, Ryan JC, Fossum S. The genes and gene organization of the Ly49 region of the rat natural killer cell gene complex. Volume 35 of Issue 1. European journal of immunology 2005. PMID: 15593300


  55. Inngjerdingen M, Rolstad B, Ryan JC. Activating and inhibitory Ly49 receptors modulate NK cell chemotaxis to CXC chemokine ligand (CXCL) 10 and CXCL12. Volume 171 of Issue 6. Journal of immunology (Baltimore, Md. : 1950) 2003. PMID: 12960311


  56. Hoelsbrekken SE, Nylenna Ø, Saether PC, Slettedal IO, Ryan JC, Fossum S, Dissen E. Cutting edge: molecular cloning of a killer cell Ig-like receptor in the mouse and rat. Volume 170 of Issue 5. Journal of immunology (Baltimore, Md. : 1950) 2003. PMID: 12594244


  57. Naper C, Hayashi S, Kveberg L, Niemi EC, Lanier LL, Vaage JT, Ryan JC. Ly-49s3 is a promiscuous activating rat NK cell receptor for nonclassical MHC class I-encoded target ligands. Volume 169 of Issue 1. Journal of immunology (Baltimore, Md. : 1950) 2002. PMID: 12077224


  58. Naper C, Hayashi S, Joly E, Butcher GW, Rolstad B, Vaage JT, Ryan JC. Ly49i2 is an inhibitory rat natural killer cell receptor for an MHC class Ia molecule (RT1-A1c). Volume 32 of Issue 7. European journal of immunology 2002. PMID: 12115624


  59. Naper C, Hayashi S, Løvik G, Kveberg L, Niemi EC, Rolstad B, Dissen E, Ryan JC, Vaage JT. Characterization of a novel killer cell lectin-like receptor (KLRH1) expressed by alloreactive rat NK cells. Volume 168 of Issue 10. Journal of immunology (Baltimore, Md. : 1950) 2002. PMID: 11994469


  60. Ma J, Znoiko S, Othersen KL, Ryan JC, Das J, Isayama T, Kono M, Oprian DD, Corson DW, Cornwall MC, Cameron DA, Harosi FI, Makino CL, Crouch RK. A visual pigment expressed in both rod and cone photoreceptors. Volume 32 of Issue 3. Neuron 2001. PMID: 11709156


  61. Daws MR, Lanier LL, Seaman WE, Ryan JC. Cloning and characterization of a novel mouse myeloid DAP12-associated receptor family. European journal of immunology 2001. PMID: 11241283


  62. Zheng YM, Liu C, Chen H, Locke D, Ryan JC, Kahn ML. Expression of the platelet receptor GPVI confers signaling via the Fc receptor gamma -chain in response to the snake venom convulxin but not to collagen. Volume 276 of Issue 16. The Journal of biological chemistry 2001. PMID: 11152687


  63. Løvik G, Vaage JT, Dissen E, Szpirer C, Ryan JC, Rolstad B. Characterization and molecular cloning of rat C1qRp, a receptor on NK cells. Volume 30 of Issue 12. European journal of immunology 2000. PMID: 11093152


  64. Nakamura MC, Hayashi S, Niemi EC, Ryan JC, Seaman WE. Activating Ly-49D and inhibitory Ly-49A natural killer cell receptors demonstrate distinct requirements for interaction with H2-D(d). The Journal of experimental medicine 2000. PMID: 10934233


  65. Kumaresan PR, Stepp SE, Verrett PC, Chuang SS, Boles KS, Lai WC, Ryan JC, Bennett M, Kumar V, Mathew PA. Molecular characterization of the rat NK cell receptor 2B4. Volume 37 of Issue 12-13. Molecular immunology 2000. PMID: 11275258


  66. Ryan JC, Niemi EC, Nakamura MC. Functional analysis of natural killer cell receptors in the RNK-16 rat leukemic cell line. Volume 121. Methods in molecular biology (Clifton, N.J.) 2000. PMID: 10818734


  67. Nakamura MC, Naper C, Niemi EC, Spusta SC, Rolstad B, Butcher GW, Seaman WE, Ryan JC. Natural killing of xenogeneic cells mediated by the mouse Ly-49D receptor. Journal of immunology (Baltimore, Md. : 1950) 1999. PMID: 10528166


  68. Eriksson M, Leitz G, Fällman E, Axner O, Ryan JC, Nakamura MC, Sentman CL. Inhibitory receptors alter natural killer cell interactions with target cells yet allow simultaneous killing of susceptible targets. Volume 190 of Issue 7. The Journal of experimental medicine 1999. PMID: 10510090


  69. Naper C, Ryan JC, Kirsch R, Butcher GW, Rolstad B, Vaage JT. Genes in two major histocompatibility complex class I regions control selection, phenotype, and function of a rat Ly-49 natural killer cell subset. Volume 29 of Issue 6. European journal of immunology 1999. PMID: 10382768


  70. Eriksson M, Ryan JC, Nakamura MC, Sentman CL. Ly49A inhibitory receptors redistribute on natural killer cells during target cell interaction. Volume 97 of Issue 2. Immunology 1999. PMID: 10447751


  71. Nakamura MC, Linnemeyer PA, Niemi EC, Mason LH, Ortaldo JR, Ryan JC, Seaman WE. Mouse Ly-49D recognizes H-2Dd and activates natural killer cell cytotoxicity. The Journal of experimental medicine 1999. PMID: 9927511


  72. Johansson MH, Höglund E, Nakamura MC, Ryan JC, Höglund P. Alpha1/alpha2 domains of H-2D(d), but not H-2L(d), induce "missing self" reactivity in vivo--no effect of H-2L(d) on protection against NK cells expressing the inhibitory receptor Ly49G2. Volume 28 of Issue 12. European journal of immunology 1998. PMID: 9862356


  73. Wakil AE, Wang ZE, Ryan JC, Fowell DJ, Locksley RM. Interferon gamma derived from CD4(+) T cells is sufficient to mediate T helper cell type 1 development. Volume 188 of Issue 9. The Journal of experimental medicine 1998. PMID: 9802977


  74. Sundbäck J, Nakamura MC, Waldenström M, Niemi EC, Seaman WE, Ryan JC, Kärre K. The alpha2 domain of H-2Dd restricts the allelic specificity of the murine NK cell inhibitory receptor Ly-49A. Journal of immunology (Baltimore, Md. : 1950) 1998. PMID: 9637511


  75. Weber JR, Orstavik S, Torgersen KM, Danbolt NC, Berg SF, Ryan JC, Taskén K, Imboden JB, Vaage JT. Molecular cloning of the cDNA encoding pp36, a tyrosine-phosphorylated adaptor protein selectively expressed by T cells and natural killer cells. The Journal of experimental medicine 1998. PMID: 9529333


  76. Naper C, Ryan JC, Nakamura MC, Lambracht D, Rolstad B, Vaage JT. Identification of an inhibitory MHC receptor on alloreactive rat natural killer cells. Volume 160 of Issue 1. Journal of immunology (Baltimore, Md. : 1950) 1998. PMID: 9551974


  77. Houchins JP, Lanier LL, Niemi EC, Phillips JH, Ryan JC. Natural killer cell cytolytic activity is inhibited by NKG2-A and activated by NKG2-C. Volume 158 of Issue 8. Journal of immunology (Baltimore, Md. : 1950) 1997. PMID: 9103421


  78. Nakamura MC, Niemi EC, Fisher MJ, Shultz LD, Seaman WE, Ryan JC. Mouse Ly-49A interrupts early signaling events in natural killer cell cytotoxicity and functionally associates with the SHP-1 tyrosine phosphatase. The Journal of experimental medicine 1997. PMID: 9034146


  79. Ryan JC, Seaman WE. Divergent functions of lectin-like receptors on NK cells. Immunological reviews 1997. PMID: 9059884


  80. Dissen E, Ryan JC, Seaman WE, Fossum S. An autosomal dominant locus, Nka, mapping to the Ly-49 region of a rat natural killer (NK) gene complex, controls NK cell lysis of allogeneic lymphocytes. The Journal of experimental medicine 1996. PMID: 8642329


  81. Ryan JC, Niemi EC, Nakamura MC, Seaman WE. NKR-P1A is a target-specific receptor that activates natural killer cell cytotoxicity. The Journal of experimental medicine 1995. PMID: 7722466


  82. Chan AC, van Oers NS, Tran A, Turka L, Law CL, Ryan JC, Clark EA, Weiss A. Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling. Journal of immunology (Baltimore, Md. : 1950) 1994. PMID: 8176201


  83. Ryan JC, Turck J, Niemi EC, Yokoyama WM, Seaman WE. Molecular cloning of the NK1.1 antigen, a member of the NKR-P1 family of natural killer cell activation molecules. Journal of immunology (Baltimore, Md. : 1950) 1992. PMID: 1506685


  84. Ryan JC, Niemi EC, Goldfien RD, Hiserodt JC, Seaman WE. NKR-P1, an activating molecule on rat natural killer cells, stimulates phosphoinositide turnover and a rise in intracellular calcium. Journal of immunology (Baltimore, Md. : 1950) 1991. PMID: 1919012


  85. Yokoyama WM, Ryan JC, Hunter JJ, Smith HR, Stark M, Seaman WE. cDNA cloning of mouse NKR-P1 and genetic linkage with LY-49. Identification of a natural killer cell gene complex on mouse chromosome 6. Journal of immunology (Baltimore, Md. : 1950) 1991. PMID: 1680927