James Deardorff, MD

Assistant Professor

James Deardorff is a geriatrician and Assistant Professor in the Division of Geriatrics at UCSF. Dr. Deardorff attended medical school at Saint Louis University, internal medicine residency at Duke University, and geriatrics fellowship at UCSF. Following a 2-year T32 aging research fellowship at UCSF, he joined the division of Geriatrics as research faculty in July 2023. He received training in epidemiology and biostatistics through the 1-year Advanced Training in Clinical Research certificate program at UCSF.

Dr. Deardorff’s research interest involves improving clinical care and decision making for medically complex older adults at critical transition points in their lives, such as a skilled nursing facility admission. He has completed two projects focused on the development of clinical prediction models to predict mortality risk and need for nursing home level of care among persons with dementia.

In his clinical work, Dr. Deardorff provides care for individuals at the Jewish Home skilled nursing facility and in the hospital on the geriatrics-orthopedic surgery co-management service and general geriatrics consult service.

Education
06/2023 - T32 Aging Research Fellow, University of California, San Francisco
06/2021 - Geriatrics Fellowship, University of California, San Francisco
06/2020 - Internal Medicine, Duke University Medical Center
MD, 05/2017 - Medicine, St. Louis University School of Medicine
BS, 06/2013 - Biochemistry, University of California, Los Angeles
Publications
  1. Deardorff WJ, Jeon SY, Barnes DE, Boscardin WJ, Langa KM, Covinsky KE, Mitchell SL, Lee SJ, Smith AK. Development and External Validation of Models to Predict Need for Nursing Home Level of Care in Community-Dwelling Older Adults With Dementia. JAMA internal medicine 2023. PMID: 38048097


  2. Deardorff WJ, Diaz-Ramirez LG, Boscardin WJ, Smith AK, Lee SJ. Around the EQUATOR with Clin-STAR: Prediction modeling opportunities and challenges in aging research. Journal of the American Geriatrics Society 2023. PMID: 38032070


  3. Deardorff WJ, Lu K, Jing B, Jeon SY, Boscardin WJ, Fung KZ, Lee SJ. Frequency of Screening for Colorectal Cancer by Predicted Life Expectancy Among Adults 76-85 Years. JAMA 2023. PMID: 37676665


  4. Deardorff WJ, Covinsky K. Incorporating Prognosis into Clinical Decision-Making for Older Adults with Diabetes. Journal of general internal medicine 2023. PMID: 37464148


  5. Deardorff WJ, Jing B, Growdon ME, Yaffe K, Boscardin WJ, Boockvar KS, Steinman MA. Medication misuse and overuse in community-dwelling persons with dementia. Journal of the American Geriatrics Society 2023. PMID: 37272899


  6. Deardorff WJ, Smith AK, Lee SJ. Improving Clinical Applicability of Mortality Prediction Models Among Persons With Dementia-Reply. JAMA internal medicine 2023. PMID: 36972064


  7. Deardorff WJ, Barnes DE, Jeon SY, Boscardin WJ, Langa KM, Covinsky KE, Mitchell SL, Whitlock EL, Smith AK, Lee SJ. Development and External Validation of a Mortality Prediction Model for Community-Dwelling Older Adults With Dementia. JAMA internal medicine 2022. PMID: 36156062


  8. Nguyen B, Deardorff WJ, Shi Y, Jing B, Lee AK, Lee SJ. Fingerstick glucose monitoring by cognitive impairment status in Veterans Affairs nursing home residents with diabetes. Journal of the American Geriatrics Society 2022. PMID: 35924668


  9. Jing B, Boscardin WJ, Deardorff WJ, Jeon SY, Lee AK, Donovan AL, Lee SJ. Comparing Machine Learning to Regression Methods for Mortality Prediction Using Veterans Affairs Electronic Health Record Clinical Data. 2022. PMID: 35352701


  10. Deardorff WJ, Binford SS, Cole I, James T, Rathfon M, Rennke S, Wallhagen M. COVID-19, masks, and hearing difficulty: Perspectives of healthcare providers. Journal of the American Geriatrics Society 2021. PMID: 34228350


  11. Deardorff WJ, Sloane RJ, Pavon JM, Hastings SN, Whitson HE. Hospitalization Risk Among Older Adults with Sensory Impairments: Development of a Prognostic Model. Volume 68 of Issue 11. Journal of the American Geriatrics Society 2020. PMID: 32852787


  12. Gholkar AA, Schmollinger S, Velasquez EF, Lo YC, Cohn W, Capri J, Dharmarajan H, Deardorff WJ, Gao LW, Abdusamad M, Whitelegge JP, Torres JZ. Regulation of Iron Homeostasis through Parkin-Mediated Lactoferrin Ubiquitylation. Volume 59 of Issue 32. Biochemistry 2020. PMID: 32786404


  13. Deardorff WJ, Liu PL, Sloane R, Van Houtven C, Pieper CF, Hastings SN, Cohen HJ, Whitson HE. Association of Sensory and Cognitive Impairment With Healthcare Utilization and Cost in Older Adults. Volume 67 of Issue 8. Journal of the American Geriatrics Society 2019. PMID: 30924932


  14. Deardorff WJ, Grossberg GT. Behavioral and psychological symptoms in Alzheimer's dementia and vascular dementia. Volume 165. Handbook of clinical neurology 2019. PMID: 31727229


  15. Deardorff WJ, Grossberg GT. A fixed-dose combination of memantine extended-release and donepezil in the treatment of moderate-to-severe Alzheimer's disease. Volume 10. Drug design, development and therapy 2016. PMID: 27757016


  16. Deardorff WJ, Grossberg GT. Pharmacotherapeutic strategies in the treatment of severe Alzheimer's disease. Volume 17 of Issue 13. Expert opinion on pharmacotherapy 2016. PMID: 27450461


  17. Deardorff WJ, Grossberg GT. Targeting neuroinflammation in Alzheimer's disease: evidence for NSAIDs and novel therapeutics. Volume 17 of Issue 1. Expert review of neurotherapeutics 2016. PMID: 27293026


  18. Nieto RA, Deardorff WJ, Grossberg GT. Efficacy of rivastigmine tartrate, transdermal system, in Alzheimer's disease. Volume 17 of Issue 6. Expert opinion on pharmacotherapy 2016. PMID: 26918774


  19. Deardorff WJ, Feen E, Grossberg GT. The Use of Cholinesterase Inhibitors Across All Stages of Alzheimer's Disease. Volume 32 of Issue 7. Drugs & aging 2015. PMID: 26033268


  20. Gholkar AA, Senese S, Lo YC, Capri J, Deardorff WJ, Dharmarajan H, Contreras E, Hodara E, Whitelegge JP, Jackson PK, Torres JZ. Tctex1d2 associates with short-rib polydactyly syndrome proteins and is required for ciliogenesis. Volume 14 of Issue 7. Cell cycle (Georgetown, Tex.) 2015. PMID: 25830415


  21. Deardorff WJ, Shobassy A, Grossberg GT. Safety and clinical effects of EVP-6124 in subjects with Alzheimer's disease currently or previously receiving an acetylcholinesterase inhibitor medication. Volume 15 of Issue 1. Expert review of neurotherapeutics 2014. PMID: 25495510


  22. Deardorff WJ, Grossberg GT. A review of the clinical efficacy, safety and tolerability of the antidepressants vilazodone, levomilnacipran and vortioxetine. Volume 15 of Issue 17. Expert opinion on pharmacotherapy 2014. PMID: 25224953