Aida Venado Estrada, MD

Associate Professor

Clinical Activities
Dr. Venado is a Pulmonary and Critical Care physician who specializes in treating patients with interstitial lung disease and patients with advanced lung disease who undergo lung transplantation.

Research and Quality Activities
In collaboration with the transplant team at UCSF, she described the natural history of frailty in patients that undergo lung transplantation. She found that pre-operative frailty rapidly improves in the six months following lung transplant. Dr. Venado and the UCSF team then demonstrated that frailty after lung transplant is associated with increased mortality and found that transplant-related complications, such as renal disease, obesity, and malnutrition, can induce frailty.
Dr. Venado is the founder of the Quality in Lung Transplant Care (QUILT) initiative at UCSF, which leverages real-world data monitoring to aim for care that preserves lung allograft function with the least possible complications of immunosuppression.
Dr. Venado serves as the Director for Quality and Safety for the Pulmonary Division at UCSF.

Activities to support Diversity
As a native Spanish speaker, Dr. Venado aims to overcome language and cultural barriers when caring for Latinx patients with advanced lung disease and lung transplant recipients.
Dr. Venado served as co-chair for the Women in Pulmonary Medicine group at UCSF.

Education
2020 - Diversity, Equity, and Inclusion Training, University of California, San Francisco
MAS, 2018 - Masters of Advanced Studies in Clinical Research, University of California, San Francisco
2016 - Lung Transplantation Fellowship, University of California, San Francisco
2015 - Pulmonary and Critical Care Medicine Fellowship, University of Alabama at Birmingham
2012 - Internal Medicine Residency, Emory University
MD, 2008 - Medicine, Universidad Nacional Autonoma de Mexico
Honors and Awards
  • Critical Care Assembly Abstract Award, American Thoracic Society, 2015
  • Best case, Infectious Disease Student/Resident Case Session, American College of Chest Physicians, 2012
  • Distinction in Social Medicine, Emory University, 2012
  • Travel Award, Southern Society for Clinical Investigation, 2011
  • Intern of the Year, General Hospital 8, IMSS, Ensenada, Baja California, 2006
Websites
Publications

  1. Seijo L, Gao Y, Betancourt L, Venado A, Hays SR, Kukreja J, Calabrese DR, Greenland JR, Singer JP. Improvements in Patient-Reported Functioning after Lung Transplant is Associated with Improved Quality of Life and Survival. medRxiv : the preprint server for health sciences 2024. PMID: 39211845


  2. Mohanty RP, Moghbeli K, Singer JP, Calabrese DR, Hays SR, Iasella C, Lieber S, Leard LE, Shah RJ, Venado A, Kleinhenz ME, Golden JA, Martinu T, Love C, Ward R, Langelier CR, McDyer J, Greenland JR. Small airway brush gene expression predicts chronic lung allograft dysfunction and mortality. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2024. PMID: 39115489


  3. Calabrese DR, Yellamilli S, Ekstrand C, Singer JP, Hays SR, Leard LE, Shah RJ, Venado A, Kolaitis NA, Perez A, Combes A, Greenland JR. Macrophage and CD8 T Cell Discordance are Associated with Acute Lung Allograft Dysfunction Progression. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2024. PMID: 38367738


  4. Prather AA, Gao Y, Betancourt L, Kordahl RC, Sriram A, Huang CY, Hays SR, Kukreja J, Calabrese DR, Venado A, Greenland JR, Singer JP. Disturbed sleep is associated with worse patient-reported outcomes and chronic lung allograft dysfunction after lung transplantation. medRxiv : the preprint server for health sciences 2023. PMID: 37873197


  5. Santos J, Wang P, Shemesh A, Liu F, Tsao T, Aguilar OA, Cleary SJ, Singer JP, Gao Y, Hays SR, Golden J, Leard LE, Kleinhenz ME, Kolaitis NA, Shah RJ, Venado A, Kukreja J, Weigt SS, Belperio JA, Lanier LL, Looney MR, Greenland JR, Calabrese DR. CCR5 drives NK cell-associated airway damage in pulmonary ischemia-reperfusion injury. JCI insight 2023. PMID: 37788115


  6. Singer JP, Gao Y, Huang CY, Kordahl RC, Sriram A, Hays SR, Kukreja J, Venado A, Calabrese DR, Greenland JR. The Association Between Frailty and Chronic Lung Allograft Dysfunction After Lung Transplantation. Transplantation 2023. PMID: 37287095


  7. Singer JP, Christie JD, Diamond JM, Anderson MA, Benvenuto LA, Gao Y, Arcasoy SM, Lederer DJ, Calabrese D, Wang P, Hays SR, Kukreja J, Venado A, Kolaitis NA, Leard LE, Shah RJ, Kleinhenz ME, Golden J, Betancourt L, Oyster M, Zaleski D, Adler J, Kalman L, Balar P, Patel S, Medikonda N, Koons B, Tevald M, Covinsky KE, Greenland JR, Katz PK. Development of the Lung Transplant Frailty Scale (LT-FS). The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2023. PMID: 36925382


  8. Singer JP, Calfee CS, Delucchi K, Diamond JM, Anderson MA, Benvenuto LA, Gao Y, Wang P, Arcasoy SM, Lederer DJ, Hays SR, Kukreja J, Venado A, Kolaitis NA, Leard L LE, Shah RJ, Kleinhenz ME, Golden J, Betancourt L, Oyster M, Brown M, Zaleski D, Medikonda N, Kalman L, Balar P, Patel S, Calabrese DR, Greenland JR, Christie JD. Subphenotypes of frailty in lung transplant candidates. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2023. PMID: 36740192


  9. Odisho AY, Liu AW, Maiorano AR, Bigazzi MOA, Medina E, Leard LE, Shah R, Venado A, Perez A, Golden J, Kleinhenz ME, Kolaitis NA, Maheshwari J, Trinh BN, Kukreja J, Greenland J, Calabrese D, Neinstein AB, Singer JP, Hays SR. Design and implementation of a digital health home spirometry intervention for remote monitoring of lung transplant function. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2023. PMID: 37031033


  10. Calabrese DR, Tsao T, Magnen M, Valet C, Gao Y, Mallavia B, Tian JJ, Aminian EA, Wang KM, Shemesh A, Punzalan EB, Sarma A, Calfee CS, Christenson SA, Langelier CR, Hays SR, Golden JA, Leard LE, Kleinhenz ME, Kolaitis NA, Shah RJ, Venado A, Lanier LL, Greenland JR, Sayah DM, Ardehali A, Kukreja J, Weigt SS, Belperio JA, Singer JP, Looney MR. NKG2D receptor activation drives primary graft dysfunction severity and poor lung transplantation outcomes. JCI insight 2022. PMID: 36346670


  11. Guo T, He C, Venado A, Zhou Y. Extracellular Matrix Stiffness in Lung Health and Disease. Comprehensive Physiology 2022. PMID: 35766837


  12. Venado A, Kukreja J, Greenland JR. Chronic Lung Allograft Dysfunction. 2022. PMID: 35512941


  13. Kolaitis NA, Gao Y, Soong A, Greenland JR, Hays SR, Golden JA, Venado A, Leard LE, Shah RJ, Kleinhenz ME, Katz PP, Kukreja J, Blanc PD, Smith PJ, Singer JP. Depressive symptoms in lung transplant recipients: trajectory and association with mortality and allograft dysfunction. 2022. PMID: 35354643


  14. Maheshwari JA, Kolaitis NA, Anderson MR, Benvenuto L, Gao Y, Katz PP, Greenland J, Wolters PJ, Covinsky K, Hays SR, Kukreja J, Calabrese DR, Venado A, Shah RJ, Leard LE, Trinh B, Huang CY, Glidden D, Kleinhenz ME, Golden JA, Sutter N, Tietje-Ulrich G, Criner RN, Arcasoy SM, Christie JD, Diamond J, Singer JP. Construct and Predictive Validity of Sarcopenia in Lung Transplant Candidates. Annals of the American Thoracic Society 2021. PMID: 33565917


  15. Crespo MM, Lease ED, Sole A, Sandorfi N, Snyder LD, Berry GJ, Pavec JL, Venado AE, Cifrian JM, Goldberg H, Dilling DF, Gries C, Nair A, Willie K, Meyer KC, Shah RJ, Tokman S, Holm A, Patterson CM, McWilliams T, Shtraichman O, Bemiss B, Salgado J, Farver C, Strah H, Wassilew K, Kaza V, Howsare M, Murray M, Bhorade S, Budev M. ISHLT consensus document on lung transplantation in patients with connective tissue disease: Part I: Epidemiology, assessment of extrapulmonary conditions, candidate evaluation, selection criteria, and pathology statements. 2021. PMID: 34417111


  16. DeBolt CL, Gao Y, Sutter N, Soong A, Leard L, Jeffrey G, Kleinhenz ME, Calabrese D, Greenland J, Venado A, Hays SR, Shah R, Kukreja J, Trinh B, Kolaitis NA, Douglas V, Diamond JM, Smith P, Singer J. The association of post-operative delirium with patient-reported outcomes and mortality after lung transplantation. Clinical transplantation 2021. PMID: 33682171


  17. Santhosh L, Harleman E, Venado A, Farrand E, E Gilbreth M, Keenan BP, Thompson VV, Shah RJ. Strategies for forming effective women's groups. The clinical teacher 2020. PMID: 33058547


  18. Kolaitis NA, Gao Y, Soong A, Greenland JR, Hays SR, Golden J, Leard LE, Shah RJ, Kleinhenz ME, Katz PP, Venado A, Kukreja J, Blanc PD, Singer JP. Primary graft dysfunction attenuates improvements in health-related quality of life after lung transplantation, but not disability or depression. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2020. PMID: 32794295


  19. Scallan C, Venado A, Han L, Xu H, Mulligan M, Raghu G. Recurrent Pulmonary Fibrosis in a Lung Allograft Secondary to De Novo Antisynthetase Syndrome. Annals of the American Thoracic Society 2020. PMID: 32437253


  20. Venado A, Kolaitis NA, Huang CY, Gao Y, Glidden DV, Soong A, Sutter N, Katz PP, Greenland JR, Calabrese DR, Hays SR, Golden JA, Shah RJ, Leard LE, Kukreja J, Deuse T, Wolters PJ, Covinsky K, Blanc PD, Singer JP. Frailty after lung transplantation is associated with impaired health-related quality of life and mortality. Thorax 2020. PMID: 32376733


  21. Venado A, Witt LJ, Kallianos K, Wolters PJ. Diaphragmatic Atrophy May Limit Progression of Idiopathic Pulmonary Fibrosis. American journal of respiratory and critical care medicine 2019. PMID: 31825660


  22. Perez AA, Hays SR, Soong A, Gao Y, Greenland JR, Leard LE, Shah RJ, Golden J, Kukreja J, Venado A, Kleinhenz ME, Singer JP. Improvements in frailty contribute to substantial improvements in quality of life after lung transplantation in patients with cystic fibrosis. Pediatric pulmonology 2020. PMID: 32237273


  23. Hinze AM, Lin CT, Hussien AF, Perin J, Venado A, Golden JA, Boin F, Brown RH, Wise RA, Wigley FM. Longitudinal assessment of interstitial lung disease in single lung transplant recipients with scleroderma. Rheumatology (Oxford, England) 2019. PMID: 31504916


  24. Mallavia B, Liu F, Lefrançais E, Cleary SJ, Kwaan N, Tian JJ, Magnen M, Sayah DM, Soong A, Chen J, Saggar R, Shino MY, Ross DJ, Derhovanessian A, Lynch Iii JP, Ardehali A, Weigt SS, Belperio JA, Hays SR, Golden JA, Leard LE, Shah RJ, Kleinhenz ME, Venado A, Kukreja J, Singer JP, Looney MR. Mitochondrial DNA Stimulates TLR9-Dependent NET Formation in Primary Graft Dysfunction. American journal of respiratory cell and molecular biology 2019. PMID: 31647878


  25. Kolaitis NA, Calabrese DR, Ahearn P, Venado A, Florez R, Lei HL, Isaak K, Henricksen E, Martinez E, Chong T, Shah RJ, Leard LE, Kleinhenz ME, Golden J, De Marco T, Greenland JR, Kukreja J, Hays SR, Blanc PD, Singer JP. Tacrolimus trough monitoring guided by mass spectrometry without accounting for assay differences is associated with acute kidney injury in lung transplant recipients. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 2019. PMID: 31696925


  26. Perez AA, Singer JP, Schwartz BS, Chin-Hong P, Shah RJ, Kleinhenz ME, Gao Y, Venado A, Leard LE, Golden JA, Kukreja J, Greenland JR, Hays SR. Management and clinical outcomes after lung transplantation in patients with pre-transplant Mycobacterium abscessus infection: A single center experience. Transplant infectious disease : an official journal of the Transplantation Society 2019. PMID: 30924986


  27. Venado A, McCulloch C, Greenland JR, Katz P, Soong A, Shrestha P, Hays S, Golden J, Shah R, Leard LE, Kleinhenz ME, Kukreja J, Zablotska L, Allen IE, Covinsky K, Blanc P, Singer JP. Frailty trajectories in adult lung transplantation: A cohort study. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2019. PMID: 31005571


  28. Singer JP, Diamond JM, Anderson MR, Katz PP, Covinsky K, Oyster M, Blue T, Soong A, Kalman L, Shrestha P, Arcasoy SM, Greenland JR, Shah L, Kukreja J, Blumenthal NP, Easthausen I, Golden JA, McBurnie A, Cantu E, Sonett J, Hays S, Robbins H, Raza K, Bacchetta M, Shah RJ, D'Ovidio F, Venado A, Christie JD, Lederer DJ. Frailty phenotypes and mortality after lung transplantation: A prospective cohort study. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2018. PMID: 29667786


  29. Chen H, Qu J, Huang X, Kurundkar A, Zhu L, Yang N, Venado A, Ding Q, Liu G, Antony VB, Thannickal VJ, Zhou Y. Mechanosensing by the a6-integrin confers an invasive fibroblast phenotype and mediates lung fibrosis. Nature communications 2016. PMID: 27535718


  30. Venado A, Wille K, Belott SC, Diaz-Guzman E. Unexplained hemolysis in patients undergoing ECMO: beware of hypertriglyceridemia. Perfusion 2014. PMID: 25361761


  31. Sharma N, Venado A, Morrison J. Protocol-based treatment of septic shock, fibrinolysis for submassive pulmonary embolism, and use of corticosteroids in acute exacerbations of chronic obstructive pulmonary disease requiring mechanical ventilation. American journal of respiratory and critical care medicine 2014. PMID: 25271746


  32. Venado A, Hoopes CW, Diaz-Guzman E. Prolonged extracorporeal membrane oxygenation use as a bridge to lung transplantation: it is time for a national registry. Chest 2014. PMID: 24394836


  33. Curry-McCoy TV, Venado A, Guidot DM, Joshi PC. Alcohol ingestion disrupts alveolar epithelial barrier function by activation of macrophage-derived transforming growth factor beta1. Respiratory research 2013. PMID: 23547562


  34. Venado A, Prebil S. Images in clinical medicine. Unexpected swallowing of a knife. The New England journal of medicine 2012. PMID: 22853016


  35. López-Cervantes M, Venado A, Moreno A, Pacheco-Domínguez RL, Ortega-Pierres G. On the spread of the novel influenza A (H1N1) virus in Mexico. Journal of infection in developing countries 2009. PMID: 19759500


  36. Gamba G, García-Romero MT, Venado A. [Past and future of the Revista de Investigación Clínica]. Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 2008. PMID: 19408423