Gender differences in experience and reporting of acute symptoms among cleaning staff.

A Live Video Dyadic Resiliency Intervention to Prevent Chronic Emotional Distress Early After Dementia Diagnoses: Protocol for a Dyadic Mixed Methods Study.

Janice Schwartz will present as part of the 2024 FDA CERSI Lecture Series

Janice Schwartz, MD will present "Voices of Diversity: Older Adults with Multiple Chronic Conditions and Their Perspectives on Clinical Trials" as part of the 2024 FDA CERSI Lecture Series on Tuesday, January 23, 2024, from 12 to 1 pm Pacific Time (3 to 4 pm Eastern Time) via Zoom. See abstract below:

Abstract:

Gold standards of clinical care are based on randomized blinded clinical trial data. Unfortunately, Black or African American, Hispanic or Latino, and other racial and ethnic minority communities, and persons with multimorbidity or disabilities have been under-represented in clinical trials relative to their presence in the patient groups that are candidates for the treatment. Sections on CLINICAL TRIAL DIVERSITY AND MODERNIZATION are part of the 2023 Omnibus Bill in an attempt to solve the problem of under-representation in clinical trials. However, enrollment of diverse older adults with multiple chronic conditions into clinical trials will not increase unless patients are willing and able to participate.

Our goals were to elucidate the priorities and perceptions about feasibility of participation and data collection (in person vs. virtual), barriers to participation, and motivators regarding clinical trial participation by 1) surveying a nationally representative sample of older adults with multiple chronic conditions and identifying differences between gender, race and ethnicity, and between very old adults compared to younger old adults; 2) conducting focus groups in English and Mandarin with Asian communities of Chinese origin; and 3) conducting focus groups in English and Spanish with Hispanic or Latino communities.

Quantitative results from the national survey and qualitative results from the focus groups in the Asian communities of Chinese origin will be presented, and preliminary results from focus groups in the Hispanic or Latino communities will be briefly mentioned. Results that differ from “conventional wisdom” or literature based on results from other groups of adults will be the focus. Overall, our data suggest that proposed changes in clinical trial design to increase enrollment of under-represented older adults may not align with patient-reported preferences.  

In: Pattengale PK, Lukes RJ, Taylor CR (Eds.), Lymphoproliferative Diseases: Pathogenesis, Diagnosis, and Therapy

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