Complete degradation of type X collagen requires the combined action of interstitial collagenase and osteoclast-derived cathepsin-B.

Dose-dependency of caffeine metabolism with repeated dosing.

NKR-P1, an activating molecule on rat natural killer cells, stimulates phosphoinositide turnover and a rise in intracellular calcium.

Identification of a novel Gammaretrovirus in prostate tumors of patients homozygous for R462Q RNASEL variant.

The efficacy and safety of enzalutamide with trastuzumab in patients with HER2+ and androgen receptor-positive metastatic or locally advanced breast cancer.

Non-invasive imaging and monitoring cardiotoxicity of cancer therapeutic drugs.

Mutation of the acetylcholine receptor alpha subunit causes a slow-channel myasthenic syndrome by enhancing agonist binding affinity.

Convergent evolution of BRCA2 reversion mutations under therapeutic pressure by PARP inhibition and platinum chemotherapy.

SFVA & ZSFG Medicine Grand Rounds - Jenni Wei, MD & Mia Lozada, MD

Jenni Wei, MD (Internal Medicine Physician, Gallup Indian Medical Center & Assistant Clinical Professor of Medicine, UCSF)

Mia Lozada, MD (Medical Officer, Gallup Indian Medical Center & Volunteer Assistant Clinical Professor of Medicine, UCSF)

Zoom information:

Meeting ID: 981 6710 4286
Password: 489529
Call-in: +1 669 900 6833
            +1 213 338 8477
            +1 669 219 2599

Full Link: https://ucsf.zoom.us/s/98167104286?pwd=T3NFK2FDTEtqZ09MUzlsSVY4TVBkQT09#success

To view recorded Medical Grand Rounds presentations, please click on the following link; https://ucsf.box.com/v/va-zsfg-grandrounds

"Due to the change in the fiscal year, TMS registration links for next week's MGR are not yet available. CME credit may still be available for attendees who sign in at the event, depending on the timing of required TMS updates." 

Meeting report: The International Conference on Human Immunity to Tuberculosis.

The COMET (Comparison of Operative versus Monitoring and Endocrine Therapy) trial: a phase III randomised controlled clinical trial for low-risk ductal carcinoma in situ (DCIS).

Comparison of procedural success and long-term outcomes of stent thrombosis in coronary bypass grafts versus native coronary arteries.

Stepping away from ritual right heart catheterization into the era of noninvasively measured pulmonary artery pressure.

Systematic reviews: perhaps "the answer to policy makers' prayers"?

Bringing Gene Therapies for HIV Disease to Resource-Limited Parts of the World.