Publications

Department of Medicine faculty members published more than 3,000 peer-reviewed articles in 2022.

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Neurology

How experienced community neurologists make diagnoses during clinical encounters.

2013

Authors: Dhand A, Engstrom J, Dhaliwal G

Addiction (Abingdon, England)

Influence of a dopamine pathway additive genetic efficacy score on smoking cessation: results from two randomized clinical trials of bupropion.

2013

Authors: David SP, Strong DR, Leventhal AM, Lancaster MA, McGeary JE, Munafò MR, Bergen AW, Swan GE, Benowitz NL, Tyndale RF, Conti DV, Brown RA, Lerman C, Niaura R

Endocrinology

Policy decisions on endocrine disruptors should be based on science across disciplines: a response to Dietrich et al.

2013

Authors: Gore AC, Balthazart J, Bikle D, Carpenter DO, Crews D, Czernichow P, Diamanti-Kandarakis E, Dores RM, Grattan D, Hof PR, Hollenberg AN, Lange C, Lee AV, Levine JE, Millar RP, Nelson RJ, Porta M, Poth M, Power DM, Prins GS, Ridgway EC, Rissman EF, Romijn JA, Sawchenko PE, Sly PD, Söder O, Taylor HS, Tena-Sempere M, Vaudry H, Wallen K, Wang Z, Wartofsky L, Watson CS

Clinical chemistry

Age, body mass, usage of exogenous estrogen, and lifestyle factors in relation to circulating sex hormone-binding globulin concentrations in postmenopausal women.

2013

Authors: Goto A, Chen BH, Song Y, Cauley J, Cummings SR, Farhat GN, Gunter M, Van Horn L, Howard BV, Jackson R, Lee J, Rexrode KM, Liu S

Journal of the National Cancer Institute

Risk factors for inflammatory breast cancer and other invasive breast cancers.

2013

Authors: Schairer C, Li Y, Frawley P, Graubard BI, Wellman RD, Buist DS, Kerlikowske K, Onega TL, Anderson WF, Miglioretti DL

JAMA

Medicare payment for chronic care delivered in a patient-centered medical home.

2013

Authors: Bindman AB, Blum JD, Kronick R

Volume 44 of Issue 6 | Archives of medical research

Association between rs2981582 polymorphism in the FGFR2 gene and the risk of breast cancer in Mexican women.

2013

Authors: Murillo-Zamora E, Moreno-Macías H, Ziv E, Romieu I, Lazcano-Ponce E, Angeles-Llerenas A, Pérez-Rodríguez E, Vidal-Millán S, Fejerman L, Torres-Mejía G

View Abstract

BACKGROUND AND AIMS

The rs2981582 single nucleotide polymorphism in the fibroblast growth factor receptor 2 gene has been consistently associated with an increased risk of breast cancer. We evaluated the effect of rs2981582 polymorphism in the FGFR2 gene on the risk of breast cancer and its interaction with non-genetic risk factors.

METHODS

A population-based case-control study was conducted in Mexico. Data from 687 cases and 907 controls were analyzed.

RESULTS

The T allele of the rs2981582 polymorphism was associated with an increased risk of breast cancer (ORper allele = 1.24, 95% CI 1.06-1.46). There was also an interaction between this polymorphism and alcohol consumption (p = 0.043). The effect of alcohol consumption on the risk of breast cancer varied according to the allelic variants of the rs2981582 polymorphism in the FGFR2 gene: OR = 3.97 (95% CI 2.10-7.49), OR = 2.01 (95% CI 1.23-3.29) and OR = 1.21 (95% CI 0.48-3.05) for genotypes CC, CT and TT, respectively.

CONCLUSIONS

This is the first study exploring the association between rs2981582 polymorphism in the FGFR2 gene and breast cancer risk in Mexican women. The interaction found may be of great public health interest because alcohol consumption is a modifiable breast cancer risk factor. Therefore, replication of this finding is of foremost importance.

View on PubMed

Volume 25 of Issue 1 | Journal of cardiovascular electrophysiology