Publications

Department of Medicine faculty members published more than 3,600 peer-reviewed articles in 2024.

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Gastroenterology

Sa1885 Incidence of and Predictors for Early Discontinuation of Biologic Therapies in Veteran Patients with Inflammatory Bowel Disease.

2016

Authors: Linda A. Feagins, Akbar K. Waljee, Jason K. Hou, Phillip Gu, Steven Kanjo, Vivek Rudrapatna, Amanda Ellis, Shail M. Govani, Jill Gaidos

Volume 118 of Issue 7 | Circulation research

Biochemistry and Biology of GDF11 and Myostatin: Similarities, Differences, and Questions for Future Investigation.

2016

Authors: Walker RG, Poggioli T, Katsimpardi L, Buchanan SM, Oh J, Wattrus S, Heidecker B, Fong YW, Rubin LL, Ganz P, Thompson TB, Wagers AJ, Lee RT

View Abstract

Growth differentiation factor 11 (GDF11) and myostatin (or GDF8) are closely related members of the transforming growth factor β superfamily and are often perceived to serve similar or overlapping roles. Yet, despite commonalities in protein sequence, receptor utilization and signaling, accumulating evidence suggests that these 2 ligands can have distinct functions in many situations. GDF11 is essential for mammalian development and has been suggested to regulate aging of multiple tissues, whereas myostatin is a well-described negative regulator of postnatal skeletal and cardiac muscle mass and modulates metabolic processes. In this review, we discuss the biochemical regulation of GDF11 and myostatin and their functions in the heart, skeletal muscle, and brain. We also highlight recent clinical findings with respect to a potential role for GDF11 and/or myostatin in humans with heart disease. Finally, we address key outstanding questions related to GDF11 and myostatin dynamics and signaling during development, growth, and aging.

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International Journal of Infectious Diseases

Disclosure of HIV status: Perspectives from infected children in India.

2016

Authors: K. Mehta, M. Ekstrand, E. Heylen, G. Sanjeeva, A. Shet

Gastroenterology

Sa1132 Limited Utilization of Diagnostic Colonoscopy Following Positive FIT in a Safety-Net System.

2016

Authors: Rachel B. Issaka, Maneesh H. Singh, Victoria Laleau, Sachi Oshima, Carly Rachocki, Urmimala Sarkar, Lukejohn Day, Ma Somsouk

Journal of the American College of Cardiology

ECHOCARDIOGRAPHIC EVALUATION OF CARDIOVASCULAR DISEASE IN ANKYLOSING SPONDYLITIS: A PROSPECTIVE CASE-CONTROL STUDY.

2016

Authors: Risheen S. Reejhsinghani, Kathryn Brown, Nelson Schiller, Grace Yoon, Lianne Gensler, Elyse Foster

Management Science

The Impact of Privacy Regulation and Technology Incentives: The Case of Health Information Exchanges.

2016

Authors: Idris Adjerid, Alessandro Acquisti, Rahul Telang, Rema Padman, Julia Adler-Milstein

Journal of the American College of Cardiology

POST-SHOCK ELECTROMECHANICAL DISSOCIATION DURING DEFIBRILLATION THRESHOLD TESTING.

2016

Authors: Hiroyuki Ito, Nitish Badhwar, Mitsuharu Kawamura, Vasanth Vedantham, Zian Tseng, Byron Lee, Randall Lee, Gregory Marcus, Edward Gerstenfeld, Melvin Scheinman

Hepato Pancreato Biliary

“Very early” intrahepatic cholangiocarcinoma may become an acceptable indication for liver transplantation. A multicenter validation study.

2016

Authors: G. Sapisochin, M. Facciuto, N. Mehta, E. Vibert, R. Hernandez-Alejandro, A.D. Pinna, S. Hwang, V.G. Agopian, G. Gores, J. Reyes, O. Soubrane, T. Reichman, P. Kim, C. Sposito, P.A. Clavien, C. Toso, N. Kneteman, J. Bruix

Hepato Pancreato Biliary

HCC recurrence following liver tranplantation should be aggresively treated to increase patient survival.

2016

Authors: G. Sapisochin, N. Mehta, I. Scalera, C. Sposito, F.Y. Yao, P. Muiesan, V. Mazzaferro, D.R. Grant

Gastroenterology

352 Sex Differences in Acetaminophen-Induced Acute Liver Injury and Acute Liver Failure.

2016

Authors: Jessica Rubin, Bilal Hameed, Michelle Gottfried, William M. Lee, Monika Sarkar