The Journal of infectious diseases
Authors: Anderson JL, Khoury G, Fromentin R, Solomon A, Chomont N, Sinclair E, Milush JM, Hartogensis W, Bacchetti P, Roche M, Tumpach C, Gartner M, Pitman MC, Epling CL, Hoh R, Hecht FM, Somsouk M, Cameron PU, Deeks SG, Lewin SR
PloS one
Authors: Krezanoski PJ, Krezanoski JD, Nxumalo N, Gabert R, Comfort AB, Khumalo P, Matshotyana K
Journal of traumatic stress
Authors: Rosen RC, Cikesh B, Fang S, Trachtenberg FL, Seal KH, Magnavita AM, Bovin MJ, Green JD, Bliwise DL, Marx BP, Keane TM
Volume 12 of Issue 12 | Circulation. Cardiovascular quality and outcomes
Authors: Dudum R, Sajja A, Amdur RL, Choi BG
Volume 61 of Issue 4 | Leukemia & lymphoma
Authors: Nahas GR, Komanduri KV, Pereira D, Goodman M, Jimenez AM, Beitinjaneh A, Wang TP, Lekakis LJ
Anti-CD19 Chimeric Antigen Receptor T cells (CAR-T) have shown dramatic efficacy in treating refractory aggressive B cell Lymphomas leading to FDA approval of axicabtagene ciloleucel and tisagenlecleucel. While long-term remission rate for both is higher than 33%, this treatment is associated with life-threatening complications including cytokine-release syndrome, encephalopathy, and lethal cerebral edema. Here we describe a case series of bone marrow failure syndromes with or without co-existing clonal myelodysplastic syndrome. Bone marrow failure was defined as absolute neutrophil count (ANC) <500 neutrophils/μL day 42 after infusion of CAR-T cells or filgrastim support to reach that number. We use "persistent cytopenias after T-cell therapy (PCTT)" to describe this syndrome which has an incidence of 38% with axicabtagene ciloleucel. Platelets <75,000/μL at the time of initiation of lymphodepleting chemotherapy and occurrence of maximum severity of cytokine-release syndrome (CRS) on day 0 or 1 after infusion of CAR-T cells are independent predictors of PCTT.
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American heart journal
Authors: Patel DM, Thiessen-Philbrook H, Brown JR, McArthur E, Moledina DG, Mansour SG, Shlipak MG, Koyner JL, Kavsak P, Whitlock RP, Everett AD, Malenka DJ, Garg AX, Coca SG, Parikh CR
International journal of behavioral medicine
Authors: Ghanem CA, El Khoury C, Mutchler MG, Ghosh-Dastidar B, Kegeles S, Balan E, Mokhbat JE, Wagner GJ
Malaria journal
Authors: Oldenburg CE, Amza A, Cooley G, Kadri B, Nassirou B, Arnold BF, Rosenthal PJ, O'Brien KS, West SK, Bailey RL, Porco TC, Keenan JD, Lietman TM, Martin DL
BMJ (Clinical research ed.)
Authors: Moynihan R, Bero L, Hill S, Johansson M, Lexchin J, Macdonald H, Mintzes B, Pearson C, Rodwin MA, Stavdal A, Stegenga J, Thombs BD, Thornton H, Vandvik PO, Wieseler B, Godlee F
The Journal of ambulatory care management
Authors: Gagliardi KS, Coleman S, Intinarelli G, Karliner L, Appelle N, Taylor B, Grumbach K
