Publications

Department of Medicine faculty members published more than 3,600 peer-reviewed articles in 2024.

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American journal of industrial medicine

Risk factors for COVID-19 among Californians working outside the home, November 2020 - May 2021.

2023

Authors: Wong J, Cummings KJ, Gibb K, Rodriguez A, Heinzerling A, Vergara XP

Journal of global health

Associations of the COVID-19 pandemic with quality of life: A cross-sectional study of older-age people with and without HIV in rural Uganda.

2023

Authors: Olivieri-Mui B, Hoeppner SS, Tong Y, Kohrt E, Quach LT, Saylor D, Seeley J, Tsai AC, Reynolds Z, Okello S, Asiimwe S, Flavia A, Sentongo R, Tindimwebwa E, Meyer AC, Nakasujja N, Paul R, Ritchie C, Greene M, Siedner MJ

Journal of thrombosis and thrombolysis

Thrombotic outcomes in patients in a large clinical enterprise following COVID-19 vaccination.

2023

Authors: Patterson WM, Greene BD, Tefera L, Bena J, Milinovich A, Mehta N, Chung MK, Kapadia S, Svensson LG, Cameron SJ

Volume 16 of Issue 5 | JACC. Cardiovascular imaging

Myocardial Injury on CMR in Patients With COVID-19 and Suspected Cardiac Involvement.

2023

Authors: Vidula MK, Rajewska-Tabor J, Cao JJ, Kang Y, Craft J, Mei W, Chandrasekaran PS, Clark DE, Poenar AM, Gorecka M, Malahfji M, Cowan E, Kwan JM, Reinhardt SW, Al-Tabatabaee S, Doeblin P, Villa ADM, Karagodin I, Alvi N, Christia P, Spetko N, Cassar MP, Park C, Nambiar L, Turgut A, Azad MR, Lambers M, Wong TC, Salerno M, Kim J, Elliott M, Raman B, Neubauer S, Tsao CW, LaRocca G, Patel AR, Chiribiri A, Kelle S, Baldassarre LA, Shah DJ, Hughes SG, Tong MS, Pyda M, Simonetti OP, Plein S, Han Y

View Abstract

BACKGROUND

Myocardial injury in patients with COVID-19 and suspected cardiac involvement is not well understood.

OBJECTIVES

The purpose of this study was to characterize myocardial injury in a multicenter cohort of patients with COVID-19 and suspected cardiac involvement referred for cardiac magnetic resonance (CMR).

METHODS

This retrospective study consisted of 1,047 patients from 18 international sites with polymerase chain reaction-confirmed COVID-19 infection who underwent CMR. Myocardial injury was characterized as acute myocarditis, nonacute/nonischemic, acute ischemic, and nonacute/ischemic patterns on CMR.

RESULTS

In this cohort, 20.9% of patients had nonischemic injury patterns (acute myocarditis: 7.9%; nonacute/nonischemic: 13.0%), and 6.7% of patients had ischemic injury patterns (acute ischemic: 1.9%; nonacute/ischemic: 4.8%). In a univariate analysis, variables associated with acute myocarditis patterns included chest discomfort (OR: 2.00; 95% CI: 1.17-3.40, P = 0.01), abnormal electrocardiogram (ECG) (OR: 1.90; 95% CI: 1.12-3.23; P = 0.02), natriuretic peptide elevation (OR: 2.99; 95% CI: 1.60-5.58; P = 0.0006), and troponin elevation (OR: 4.21; 95% CI: 2.41-7.36; P < 0.0001). Variables associated with acute ischemic patterns included chest discomfort (OR: 3.14; 95% CI: 1.04-9.49; P = 0.04), abnormal ECG (OR: 4.06; 95% CI: 1.10-14.92; P = 0.04), known coronary disease (OR: 33.30; 95% CI: 4.04-274.53; P = 0.001), hospitalization (OR: 4.98; 95% CI: 1.55-16.05; P = 0.007), natriuretic peptide elevation (OR: 4.19; 95% CI: 1.30-13.51; P = 0.02), and troponin elevation (OR: 25.27; 95% CI: 5.55-115.03; P < 0.0001). In a multivariate analysis, troponin elevation was strongly associated with acute myocarditis patterns (OR: 4.98; 95% CI: 1.76-14.05; P = 0.003).

CONCLUSIONS

In this multicenter study of patients with COVID-19 with clinical suspicion for cardiac involvement referred for CMR, nonischemic and ischemic patterns were frequent when cardiac symptoms, ECG abnormalities, and cardiac biomarker elevations were present.

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