Michael Matthay, MD


Pulmonary, Critical Care, Allergy and Sleep Medicine

Dr. Matthay's overall focus is on improving clinical care of patients with acute respiratory failure from the acute respiratory distress syndrome and from sepsis. His research and clinical trials groups are very well funded by grants from the National Institute of Health. He also spends considerable time mentoring physicians and young faculty in career development and academic medicine.

Fellowship, 1979 - Cardiovascular Research Institute, University of California, San Francisco
Fellowship, 1978 - Pulmonary DIvision, University of California, San Francisco
Internship and Residency, 1976 - Internal Medicine, University of Colorado Medical Center
M.D., 1973 - School of Medicine, University of Pennsylvania
A.B., 1969 - English, Harvard University
Honors and Awards
  • Edward Livingston Trudeau Medal, American Thoracic Society, 2014
  • Lifetime Achievement in Mentoring Award, University of California, San Francisco, 2013
  • Honora Causa, University of Paris, 2011
  • Julius Comroe, Jr. Award, American Physiologic Society, 2009
  • Trudeau Award, New York State Thoracic Society, 2009
  • Roger Bone Memorial Lecture, American College of Chest Physicians, 2006
  • Distinguished Clinical Research Lecture, University of California, San Francisco, 2006
  • Scientific Achievement Award, American Thoracic Society, 2002
  • Elected Member, American Association of Physicians, 2001
  • Elected Member, Western Association of Physicians, 1995
  • Henry Christian Award for Excellence in Research, AFCR, 1991
  • Elected Senior Member, Scientific Staff, Cardiovascular Research Institute, UCSF, 1989
  • Elected Member, American Physiologic Society, 1986
  • Elected Associate Member, Scientific Staff, Cardiovascular Research Institute, UCSF, 1984
  • Outstanding Student in Clinical Medicine, University of Pennsylvania School of Medicine, 1973
  1. Cassandras M, Wang C, Kathiriya J, Tsukui T, Matatia P, Matthay M, Wolters P, Molofsky A, Sheppard D, Chapman H, Peng T. Gli1+ mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung. 2020. PMID: 33046884

  2. Kwong YD, Mehta K, Miaskowski C, Zhuo H, Yee K, Jauregui A, Ke S, Deiss T, Abbott J, Kangelaris KN, Sinha P, Hendrickson CM, Gomez A, Leligdowicz A, Matthay MA, Calfee CS, Liu KD. Using Best Subsets Regression to Identify Clinical Characteristics and Biomarkers Associated with Sepsis-Associated Acute Kidney Injury. 2020. PMID: 33044866

  3. Wilfong EM, Croze R, Fang X, Schwede M, Niemi E, López GY, Lee JW, Nakamura MC, Matthay MA. Proinflammatory cytokines and ARDS pulmonary edema fluid induce CD40 on human mesenchymal stromal cells-A potential mechanism for immune modulation. 2020. PMID: 33021986

  4. Matthay MA, Leligdowicz A, Liu KD. Biological Mechanisms of COVID-19 ARDS. 2020. PMID: 32997945

  5. Leligdowicz A, Ross JT, Nesseler N, Matthay MA. The endogenous capacity to produce proinflammatory mediators by the ex vivo human perfused lung. 2020. PMID: 32955627

  6. Reilly JP, Meyer NJ, Shashaty MG, Anderson BJ, Ittner C, Dunn TG, Lim B, Forker C, Bonk MP, Kotloff ED, Feng R, Cantu E, Mangalmurti NS, Calfee CS, Matthay MA, Mikacenic C, Walley KR, Russell JA, Christiani DC, Wurfel MM, Lanken PN, Reilly MP, Christie JD. The ABO Histo-Blood Group, endothelial activation, and acute respiratory distress syndrome risk in critical illness. 2020. PMID: 32931480

  7. Ji HJ, Su Z, Zhao R, Komissarov AA, Yi G, Liu SL, Idell S, Matthay MA. Insufficient hyperfibrinolysis in COVID-19: a systematic review of thrombolysis based on meta-analysis and meta-regression. 2020. PMID: 32935113

  8. Abreu SC, Hampton TH, Hoffman E, Dearborn J, Ashare A, Singh Sidhu K, Matthews DE, McKenna DH, Amiel E, Barua J, Krasnodembskaya A, English K, Mahon BP, Santos CD, Cruz FF, Chambers DC, Liu KD, Matthay MA, Cramer RA, Stanton BA, Rocco PRM, Wargo MJ, Weiss DJ, Rolandsson Enes S. Differential effects of the cystic fibrosis lung inflammatory environment on mesenchymal stromal cells. 2020. PMID: 32901521

  9. Roubinian NH, Chowdhury D, Hendrickson JE, Triulzi DJ, Gottschall JL, Looney MR, Matthay MA, Kor DJ, Brambilla D, Kleinman SH, Murphy EL. NT-proBNP levels in the identification and classification of pulmonary transfusion reactions. 2020. PMID: 32905629

  10. Matsumoto S, Fang X, Traber MG, Jones KD, Langelier C, Hayakawa Serpa P, Calfee CS, Matthay MA, Gotts JE. Dose-Dependent Pulmonary Toxicity of Aerosolized Vitamin E Acetate. 2020. PMID: 32822237

  11. Files DC, Liu KD, Matthay M. Need for Additional Trials of Vitamin C for Sepsis. 2020. PMID: 32780134

  12. Millar JE, Bartnikowski N, Passmore MR, Obonyo NG, Malfertheiner MV, von Bahr V, Redd MA, See Hoe L, Ki KK, Pedersen S, Boyle AJ, Baillie JK, Shekar K, Palpant N, Suen JY, Matthay MA, McAuley DF, Fraser JF. Combined Mesenchymal Stromal Cell Therapy and ECMO in ARDS: A Controlled Experimental Study in Sheep. 2020. PMID: 32293914

  13. Ward SL, Dahmer MK, Weeks HM, Sapru A, Quasney MW, Curley MAQ, Liu KD, Matthay MA, Flori HR. Association of patient weight status with plasma surfactant protein D, a biomarker of alveolar epithelial injury, in children with acute respiratory failure. 2020. PMID: 32725941

  14. Sinha P, Matthay MA, Calfee CS. Is a "Cytokine Storm" Relevant to COVID-19? 2020. PMID: 32602883

  15. Ross JT, Nesseler N, Leligdowicz A, Zemans RL, Mahida RY, Minus E, Langelier C, Gotts JE, Matthay MA. THE EX-VIVO PERFUSED HUMAN LUNG IS RESISTANT TO INJURY BY HIGH-DOSE S. PNEUMONIAE BACTEREMIA. 2020. PMID: 32519893

  16. Schwede M, Lee RY, Zhuo H, Kangelaris KN, Jauregui A, Vessel K, Belzer A, Deiss T, Matthay MA, Liu KD, Calfee CS. Clinician Recognition of the Acute Respiratory Distress Syndrome: Risk Factors for Under-Recognition and Trends Over Time. 2020. PMID: 32317598

  17. Kohne JG, Dahmer MK, Weeks HM, Kaciroti N, Quasney MW, Sapru A, Curley MAQ, Matthay M, Flori H. Impact of Bilateral Infiltrates on Inflammatory Biomarker Levels and Clinical Outcomes of Children With Oxygenation Defect. 2020. PMID: 32317601

  18. Zhao R, Ali G, Nie HG, Chang Y, Bhattarai D, Su X, Zhao X, Matthay MA, Ji HL. Plasmin improves blood-gas barrier function in oedematous lungs by cleaving epithelial sodium channels. 2020. PMID: 32133621

  19. Baron RM, Christman JW, Liu KD, Matthay MA, Self WH, McVerry BJ, Hite RD, Paine R, Wurfel MM, Shapiro NI, Adams PW, Schmidt EP, Ringwood N. Monitoring Research Blood Sampling in Critically Ill Patients: Avoiding Iatrogenic Anemia. 2020. PMID: 32357306

  20. Block BL, Jeon SY, Sudore RL, Matthay MA, Boscardin WJ, Smith AK. Patterns and Trends in Advance Care Planning Among Older Adults Who Received Intensive Care at the End of Life. 2020. PMID: 32119031

  21. Flitter BA, Fang X, Matthay MA, Gronert K. The potential of lipid mediator networks as ocular surface therapeutics and biomarkers. 2020. PMID: 32360792

  22. Tsukui T, Sun KH, Wetter JB, Wilson-Kanamori JR, Hazelwood LA, Henderson NC, Adams TS, Schupp JC, Poli SD, Rosas IO, Kaminski N, Matthay MA, Wolters PJ, Sheppard D. Collagen-producing lung cell atlas identifies multiple subsets with distinct localization and relevance to fibrosis. 2020. PMID: 32317643

  23. Carla A, Pereira B, Boukail H, Audard J, Pinol-Domenech N, De Carvalho M, Blondonnet R, Zhai R, Morand D, Lambert C, Sapin V, Ware LB, Calfee CS, Bastarache JA, Laffey JG, Juffermans NP, Bos LD, Artigas A, Rocco PRM, Matthay MA, McAuley DF, Constantin JM, Jabaudon M. Acute respiratory distress syndrome subphenotypes and therapy responsive traits among preclinical models: protocol for a systematic review and meta-analysis. 2020. PMID: 32264897

  24. Vranas KC, Ouyang D, Lin AL, Slatore CG, Sullivan DR, Prasad Kerlin M, Liu KD, Baron RM, Calfee CS, Ware LB, Halpern S, Matthay MA, Herridge M, Mehta S, Rogers AJ. Gender Differences in Authorship of Critical Care Literature. 2020. PMID: 31968182

  25. Ji HL, Zhao R, Matalon S, Matthay MA. Elevated Plasmin(ogen) as a Common Risk Factor for COVID-19 Susceptibility. 2020. PMID: 32216698

  26. Auriemma CL, Zhuo H, Delucchi K, Deiss T, Liu T, Jauregui A, Ke S, Vessel K, Lippi M, Seeley E, Kangelaris KN, Gomez A, Hendrickson C, Liu KD, Matthay MA, Ware LB, Calfee CS. Acute respiratory distress syndrome-attributable mortality in critically ill patients with sepsis. 2020. PMID: 32206845

  27. Matthay MA, Aldrich JM, Gotts JE. Treatment for severe acute respiratory distress syndrome from COVID-19. 2020. PMID: 32203709

  28. Semler MW, Bernard GR, Aaron SD, Angus DC, Biros MH, Brower RG, Calfee CS, Colantuoni EA, Ferguson ND, Gong MN, Hopkins RO, Hough CL, Iwashyna TJ, Levy BD, Martin TR, Matthay MA, Mizgerd JP, Moss M, Needham DM, Self WH, Seymour CW, Stapleton RD, Thompson BT, Wunderink RG, Aggarwal NR, Reineck LA. Identifying Clinical Research Priorities in Adult Pulmonary and Critical Care: NHLBI Working Group Report. 2020. PMID: 32150460

  29. Hamilton BCS, Dincheva GR, Matthay MA, Hays S, Singer JP, Brzezinski M, Kukreja J. Improved survival after lung transplantation for adults requiring preoperative invasive mechanical ventilation: A national cohort study. 2020. PMID: 32252988

  30. Harhay MO, Casey JD, Clement M, Collins SP, Gayat É, Gong MN, Jaber S, Laterre PF, Marshall JC, Matthay MA, Monroe RE, Rice TW, Rubin E, Self WH, Mebazaa A. Contemporary strategies to improve clinical trial design for critical care research: insights from the First Critical Care Clinical Trialists Workshop. 2020. PMID: 32072303

  31. Liu S, Wang C, Green G, Zhuo H, Liu KD, Kangelaris KN, Gomez A, Jauregui A, Vessel K, Ke S, Hendrickson C, Matthay MA, Calfee CS, Ware LB, Wolters PJ. Peripheral Blood Leukocyte Telomere Length is Associated with Survival of Sepsis Patients. 2019. PMID: 31619475

  32. Jones TK, Feng R, Kerchberger VE, Reilly JP, Anderson BJ, Shashaty MGS, Wang F, Dunn TG, Riley TR, Abbott J, Ittner CAG, Christiani DC, Mikacenic C, Wurfel MM, Ware LB, Calfee CS, Matthay MA, Christie JD, Meyer NJ. Plasma sRAGE Acts as Genetically Regulated Causal Intermediate in Sepsis-Associated ARDS. 2019. PMID: 31487195

  33. Rogers AJ, Desai M, Matthay MA, Choi AM, Baron RM. The authors reply. 2020. PMID: 31833991

  34. Anderson BJ, Calfee CS, Liu KD, Reilly JP, Kangelaris KN, Shashaty MGS, Lazaar AL, Bayliffe AI, Gallop RJ, Miano TA, Dunn TG, Johansson E, Abbott J, Jauregui A, Deiss T, Vessel K, Belzer A, Zhuo H, Matthay MA, Meyer NJ, Christie JD. Plasma sTNFR1 and IL8 for prognostic enrichment in sepsis trials: a prospective cohort study. 2019. PMID: 31818332

  35. Kwong YD, Chen S, Bouajram R, Li F, Matthay MA, Mehta KM, Glidden DV, Liu KD. The value of kinetic glomerular filtration rate estimation on medication dosing in acute kidney injury. 2019. PMID: 31770424

  36. Liu A, Park JH, Zhang X, Sugita S, Naito Y, Lee JH, Kato H, Hao Q, Matthay MA, Lee JW. Therapeutic Effects of Hyaluronic Acid in Bacterial Pneumonia in the Ex Vivo Perfused Human Lungs. 2019. PMID: 31390880

  37. Zhao R, Ali G, Chang J, Komatsu S, Tsukasaki Y, Nie HG, Chang Y, Zhang M, Liu Y, Jain K, Jung BG, Samten B, Jiang D, Liang J, Ikebe M, Matthay MA, Ji HL. Proliferative regulation of alveolar epithelial type 2 progenitor cells by human Scnn1d gene. 2019. PMID: 31754387

  38. Abreu SC, Enes SR, Dearborn J, Goodwin M, Coffey A, Borg ZD, Dos Santos CC, Wargo MJ, Cruz FF, Loi R, DeSarno M, Ashikaga T, Antunes MA, Rocco PRM, Liu KD, Lee JW, Matthay MA, McKenna DH, Weiss DJ. Lung Inflammatory Environments Differentially Alter Mesenchymal Stromal Cell Behavior. 2019. PMID: 31553626

  39. Gotts JE, Bernard O, Chun L, Croze RH, Ross JT, Nesseler N, Wu X, Abbott J, Fang X, Calfee CS, Matthay MA. Clinically Relevant Model of Pneumococcal Pneumonia, ARDS, and Non-Pulmonary Organ Dysfunction in Mice. 2019. PMID: 31509438

  40. Hanudel MR, Zinter MS, Chen L, Gala K, Lim M, Guglielmo M, Deshmukh T, Vangala S, Matthay M, Sapru A. Plasma total fibroblast growth factor 23 levels are associated with acute kidney injury and mortality in children with acute respiratory distress syndrome. 2019. PMID: 31487315

  41. White DB, Carson S, Anderson W, Steingrub J, Bird G, Curtis JR, Matthay M, Peterson M, Buddadhumaruk P, Shields AM, Ernecoff N, Shotsberger K, Weissfeld L, Chang CH, Pike F, Lo B, Hough CL. A Multicenter Study of the Causes and Consequences of Optimistic Expectations About Prognosis by Surrogate Decision-Makers in ICUs. 2019. PMID: 31162200

  42. Rogers AJ, Guan J, Trtchounian A, Hunninghake GM, Kaimal R, Desai M, Kozikowski LA, DeSouza L, Mogan S, Liu KD, Matthay MA, Steingrub J, Wheeler A, Yoon JH, Nakahira K, Choi AM, Baron RM. Association of Elevated Plasma Interleukin 18 Level With Increased Mortality in a Clinical Trial of Statin Treatment for Acute Respiratory Distress Syndrome. 2019. PMID: 31206358

  43. Niemann CU, Matthay MA, Ware LB. The Continued Need for Clinical Trials in Deceased Organ Donor Management. 2018. PMID: 30399123

  44. Ross JT, Nesseler N, Lee JW, Ware LB, Matthay MA. The ex vivo human lung: research value for translational science. 2019. PMID: 31167972

  45. Papolos AI, Schiller NB, Belzer A, Zhuo H, Gotts JE, Bibby D, Calfee CS, Matthay MA. Pulmonary Dead Space Monitoring: Identifying Subjects With ARDS at Risk of Developing Right Ventricular Dysfunction. 2019. PMID: 31138736

  46. Huppert LA, Matthay MA, Ware LB. Pathogenesis of Acute Respiratory Distress Syndrome. 2019. PMID: 31060086

  47. Scheunemann LP, Ernecoff NC, Buddadhumaruk P, Carson SS, Hough CL, Curtis JR, Anderson WG, Steingrub J, Lo B, Matthay M, Arnold RM, White DB. Clinician-Family Communication About Patients' Values and Preferences in Intensive Care Units. 2019. PMID: 30933293

  48. Flori H, Sapru A, Quasney MW, Gildengorin G, Curley MAQ, Matthay MA, Dahmer MK. A prospective investigation of interleukin-8 levels in pediatric acute respiratory failure and acute respiratory distress syndrome. 2019. PMID: 30995942

  49. Bhatraju PK, Zelnick LR, Herting J, Katz R, Mikacenic C, Kosamo S, Morrell ED, Robinson-Cohen C, Calfee CS, Christie JD, Liu KD, Matthay MA, Hahn WO, Dmyterko V, Slivinski NSJ, Russell JA, Walley KR, Christiani DC, Liles WC, Himmelfarb J, Wurfel MM. Identification of Acute Kidney Injury Subphenotypes with Differing Molecular Signatures and Responses to Vasopressin Therapy. 2019. PMID: 30334632

  50. Zinter MS, Spicer AC, Liu KD, Orwoll BE, Alkhouli MF, Brakeman PR, Calfee CS, Matthay MA, Sapru A. Positive Cumulative Fluid Balance Is Associated With Mortality in Pediatric Acute Respiratory Distress Syndrome in the Setting of Acute Kidney Injury. 2019. PMID: 30672838

  51. Matthay MA, Zhuo H, Gotts JE, Liu KD, Calfee CS. Precision medicine for cell therapy in acute respiratory distress syndrome - Authors' reply. 2019. PMID: 30926051

  52. Fielding-Singh V, Matthay MA, Calfee CS. The authors reply. 2019. PMID: 30882440

  53. Fielding-Singh V, Matthay MA, Calfee CS. The authors reply. 2019. PMID: 30882446

  54. Matthay MA, Zemans RL, Zimmerman GA, Arabi YM, Beitler JR, Mercat A, Herridge M, Randolph AG, Calfee CS. Acute respiratory distress syndrome. 2019. PMID: 30872586

  55. Leligdowicz A, Matthay MA. AIMing Immunomodulation Therapy at Sepsis. 2019. PMID: 30365342

  56. Lanspa MJ, Gong MN, Schoenfeld DA, Lee KT, Grissom CK, Hou PC, Serpa-Neto A, Brown SM, Iwashyna TJ, Yealy DM, Hough CL, Brower RG, Calfee CS, Hyzy RC, Matthay MA, Miller RR, Steingrub JS, Thompson BT, Miller CD, Clemmer TP, Hendey GW, Huang DT, Mathews KS, Qadir N, Tidswell M. Prospective Assessment of the Feasibility of a Trial of Low-Tidal Volume Ventilation for Patients with Acute Respiratory Failure. 2019. PMID: 30407869

  57. Sinha P, Calfee CS, Beitler JR, Soni N, Ho K, Matthay MA, Kallet RH. Physiologic Analysis and Clinical Performance of the Ventilatory Ratio in Acute Respiratory Distress Syndrome. 2019. PMID: 30211618

  58. Zinter MS, Delucchi KL, Kong MY, Orwoll BE, Spicer AS, Lim MJ, Alkhouli MF, Ratiu AE, McKenzie AV, McQuillen PS, Dvorak CC, Calfee CS, Matthay MA, Sapru A. Early Plasma Matrix Metalloproteinase Profiles. A Novel Pathway in Pediatric Acute Respiratory Distress Syndrome. 2019. PMID: 30114376

  59. Matthay MA. ECMO in severe acute respiratory distress syndrome. 2019. PMID: 30642777

  60. Reilly JP, Zhao Z, Shashaty MGS, Koyama T, Christie JD, Lanken PN, Wang C, Balmes JR, Matthay MA, Calfee CS, Ware LB. Low to Moderate Air Pollutant Exposure and Acute Respiratory Distress Syndrome after Severe Trauma. 2018. PMID: 30067389

  61. Langelier C, Kalantar KL, Moazed F, Wilson MR, Crawford ED, Deiss T, Belzer A, Bolourchi S, Caldera S, Fung M, Jauregui A, Malcolm K, Lyden A, Khan L, Vessel K, Quan J, Zinter M, Chiu CY, Chow ED, Wilson J, Miller S, Matthay MA, Pollard KS, Christenson S, Calfee CS, DeRisi JL. Integrating host response and unbiased microbe detection for lower respiratory tract infection diagnosis in critically ill adults. 2018. PMID: 30482864

  62. Matthay MA, Calfee CS, Zhuo H, Thompson BT, Wilson JG, Levitt JE, Rogers AJ, Gotts JE, Wiener-Kronish JP, Bajwa EK, Donahoe MP, McVerry BJ, Ortiz LA, Exline M, Christman JW, Abbott J, Delucchi KL, Caballero L, McMillan M, McKenna DH, Liu KD. Treatment with allogeneic mesenchymal stromal cells for moderate to severe acute respiratory distress syndrome (START study): a randomised phase 2a safety trial. 2018. PMID: 30455077

  63. Huppert LA, Liu KD, Matthay MA. Therapeutic potential of mesenchymal stromal cells in the treatment of ARDS. 2018. PMID: 30383290

  64. Reilly JP, Wang F, Jones TK, Palakshappa JA, Anderson BJ, Shashaty MGS, Dunn TG, Johansson ED, Riley TR, Lim B, Abbott J, Ittner CAG, Cantu E, Lin X, Mikacenic C, Wurfel MM, Christiani DC, Calfee CS, Matthay MA, Christie JD, Feng R, Meyer NJ. Plasma angiopoietin-2 as a potential causal marker in sepsis-associated ARDS development: evidence from Mendelian randomization and mediation analysis. 2018. PMID: 30343317

  65. Sinha P, Delucchi KL, Thompson BT, McAuley DF, Matthay MA, Calfee CS. Latent class analysis of ARDS subphenotypes: a secondary analysis of the statins for acutely injured lungs from sepsis (SAILS) study. 2018. PMID: 30291376

  66. Moazed F, Chun L, Matthay MA, Calfee CS, Gotts J. Assessment of industry data on pulmonary and immunosuppressive effects of IQOS. 2018. PMID: 30158203

  67. Chun L, Moazed F, Matthay M, Calfee C, Gotts J. Possible hepatotoxicity of IQOS. 2018. PMID: 30131373

  68. Liu C, Ma Y, Su Z, Zhao R, Zhao X, Nie HG, Xu P, Zhu L, Zhang M, Li X, Zhang X, Matthay MA, Ji HL. Meta-Analysis of Preclinical Studies of Fibrinolytic Therapy for Acute Lung Injury. 2018. PMID: 30177934

  69. Park J, Kim S, Lim H, Liu A, Hu S, Lee J, Zhuo H, Hao Q, Matthay MA, Lee JW. Therapeutic effects of human mesenchymal stem cell microvesicles in an ex vivo perfused human lung injured with severe E. coli pneumonia. 2018. PMID: 30076187

  70. Calfee CS, Delucchi KL, Sinha P, Matthay MA, Hackett J, Shankar-Hari M, McDowell C, Laffey JG, O'Kane CM, McAuley DF. Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial. 2018. PMID: 30078618

  71. Hsu RK, Truwit JD, Matthay MA, Levitt JE, Thompson BT, Liu KD. Effect of Rosuvastatin on Acute Kidney Injury in Sepsis-Associated Acute Respiratory Distress Syndrome. 2018. PMID: 30116543

  72. Schwede M, Wilfong EM, Zemans RL, Lee PJ, Dos Santos C, Fang X, Matthay MA. Effects of bone marrow-derived mesenchymal stromal cells on gene expression in human alveolar type II cells exposed to TNF-a, IL-1ß, and IFN-?. 2018. PMID: 30136410

  73. Jabaudon M, Blondonnet R, Pereira B, Cartin-Ceba R, Lichtenstern C, Mauri T, Determann RM, Drabek T, Hubmayr RD, Gajic O, Uhle F, Coppadoro A, Pesenti A, Schultz MJ, Ranieri MV, Brodska H, Mrozek S, Sapin V, Matthay MA, Constantin JM, Calfee CS. Plasma sRAGE is independently associated with increased mortality in ARDS: a meta-analysis of individual patient data. 2018. PMID: 30051136

  74. Leligdowicz A, Chun LF, Jauregui A, Vessel K, Liu KD, Calfee CS, Matthay MA. Human pulmonary endothelial cell permeability after exposure to LPS-stimulated leukocyte supernatants derived from patients with early sepsis. 2018. PMID: 30024307

  75. Wang C, de Mochel NSR, Christenson SA, Cassandras M, Moon R, Brumwell AN, Byrnes LE, Li A, Yokosaki Y, Shan P, Sneddon JB, Jablons D, Lee PJ, Matthay MA, Chapman HA, Peng T. Expansion of hedgehog disrupts mesenchymal identity and induces emphysema phenotype. 2018. PMID: 29999500

  76. Pecanac KE, Brown RL, Steingrub J, Anderson W, Matthay MA, White DB. A psychometric study of the decisional conflict scale in surrogate decision makers. 2018. PMID: 30054105

  77. Ross JT, Matthay MA, Harris HW. Secondary peritonitis: principles of diagnosis and intervention. 2018. PMID: 29914871

  78. Warren MA, Zhao Z, Koyama T, Bastarache JA, Shaver CM, Semler MW, Rice TW, Matthay MA, Calfee CS, Ware LB. Severity scoring of lung oedema on the chest radiograph is associated with clinical outcomes in ARDS. 2018. PMID: 29903755

  79. Kotas ME, Matthay MA. Mesenchymal stromal cells and macrophages in sepsis: new insights. Volume 51 of Issue 4. 2018. PMID: 29700107

  80. Roubinian NH, Hendrickson JE, Triulzi DJ, Gottschall JL, Michalkiewicz M, Chowdhury D, Kor DJ, Looney MR, Matthay MA, Kleinman SH, Brambilla D, Murphy EL. Contemporary Risk Factors and Outcomes of Transfusion-Associated Circulatory Overload. 2018. PMID: 29300236

  81. Hendrickson CM, Matthay MA. Endothelial biomarkers in human sepsis: pathogenesis and prognosis for ARDS. 2018. PMID: 29575977

  82. Gotts JE, Chun L, Abbott J, Fang X, Takasaka N, Nishimura SL, Springer ML, Schick SF, Calfee CS, Matthay MA. Cigarette smoke exposure worsens acute lung injury in antibiotic-treated bacterial pneumonia in mice. 2018. PMID: 29543040

  83. Florence JM, Krupa A, Booshehri LM, Davis SA, Matthay MA, Kurdowska AK. Inhibiting Bruton's tyrosine kinase rescues mice from lethal influenza-induced acute lung injury. 2018. PMID: 29516781

  84. Sung N, Aldrich JM, Shimabukuro DW, Matthay MA, Liu KD. Assessing Preventable Harms in the Intensive Care Unit: Data From a Tertiary Care Academic Medical Institution. 2018. PMID: 29473421

  85. Hamilton BCS, Dincheva GR, Zhuo H, Golden JA, Brzezinski M, Singer JP, Matthay MA, Kukreja J. Elevated donor plasminogen activator inhibitor-1 levels and the risk of primary graft dysfunction. 2018. PMID: 29377268

  86. Gupta N, Sinha R, Krasnodembskaya A, Xu X, Nizet V, Matthay MA, Griffin JH. The TLR4-PAR1 Axis Regulates Bone Marrow Mesenchymal Stromal Cell Survival and Therapeutic Capacity in Experimental Bacterial Pneumonia. 2018. PMID: 29396891

  87. Gotts JE, Matthay MA. Cell-based Therapy in Sepsis. A Step Closer. 2018. PMID: 29072926

  88. Potter DR, Miyazawa BY, Gibb SL, Deng X, Togaratti PP, Croze RH, Srivastava AK, Trivedi A, Matthay M, Holcomb JB, Schreiber MA, Pati S. Mesenchymal stem cell-derived extracellular vesicles attenuate pulmonary vascular permeability and lung injury induced by hemorrhagic shock and trauma. 2018. PMID: 29251710

  89. Matthay MA, Abman SH. Exosome-based Therapy for Bronchopulmonary Dysplasia. 2018. PMID: 28957642

  90. Schell-Chaple HM, Liu KD, Matthay MA, Puntillo KA. Rectal and Bladder Temperatures vs Forehead Core Temperatures Measured With SpotOn Monitoring System. 2018. PMID: 29292274

  91. Kortz TB, Sawe HR, Murray B, Enanoria W, Matthay MA, Reynolds T. Clinical Presentation and Outcomes among Children with Sepsis Presenting to a Public Tertiary Hospital in Tanzania. 2017. PMID: 29312910

  92. Agrawal PB, Wang R, Li HL, Schmitz-Abe K, Simone-Roach C, Chen J, Shi J, Louie T, Sheng S, Towne MC, Brainson CF, Matthay MA, Kim CF, Bamshad M, Emond MJ, Gerard NP, Kleyman TR, Gerard C. The Epithelial Sodium Channel Is a Modifier of the Long-Term Nonprogressive Phenotype Associated with F508del CFTR Mutations. 2017. PMID: 28708422

  93. Ding Y, Zhao R, Zhao X, Matthay MA, Nie HG, Ji HL. ENaCs as Both Effectors and Regulators of MiRNAs in Lung Epithelial Development and Regeneration. 2017. PMID: 29179210

  94. Guillamat-Prats R, Puig F, Camprubí-Rimblas M, Herrero R, Serrano-Mollar A, Gómez MN, Tijero J, Matthay MA, Blanch L, Artigas A. Intratracheal instillation of alveolar type II cells enhances recovery from acute lung injury in rats. 2017. PMID: 29229270

  95. Fiore-Gartland A, Panoskaltsis-Mortari A, Agan AA, Mistry AJ, Thomas PG, Matthay MA, Hertz T, Randolph AG. Cytokine Profiles of Severe Influenza Virus-Related Complications in Children. 2017. PMID: 29163498

  96. Chun LF, Moazed F, Calfee CS, Matthay MA, Gotts JE. Reply to "Letter to the Editor: Pulmonary toxicity of electronic cigarettes: more doubts than certainties". 2017. PMID: 29109110

  97. Gotts JE, Abbott J, Fang X, Yanagisawa H, Takasaka N, Nishimura SL, Calfee CS, Matthay MA. Cigarette Smoke Exposure Worsens Endotoxin-Induced Lung Injury and Pulmonary Edema in Mice. 2017. PMID: 28340238

  98. Ware LB, Zhao Z, Koyama T, Brown RM, Semler MW, Janz DR, May AK, Fremont RD, Matthay MA, Cohen MJ, Calfee CS. Derivation and validation of a two-biomarker panel for diagnosis of ARDS in patients with severe traumatic injuries. 2017. PMID: 29766112

  99. Xi Y, Kim T, Brumwell AN, Driver IH, Wei Y, Tan V, Jackson JR, Xu J, Lee DK, Gotts JE, Matthay MA, Shannon JM, Chapman HA, Vaughan AE. Local lung hypoxia determines epithelial fate decisions during alveolar regeneration. 2017. PMID: 28737769

  100. Czikora I, Alli AA, Sridhar S, Matthay MA, Pillich H, Hudel M, Berisha B, Gorshkov B, Romero MJ, Gonzales J, Wu G, Huo Y, Su Y, Verin AD, Fulton D, Chakraborty T, Eaton DC, Lucas R. Epithelial Sodium Channel-a Mediates the Protective Effect of the TNF-Derived TIP Peptide in Pneumolysin-Induced Endothelial Barrier Dysfunction. 2017. PMID: 28785264

  101. Artigas A, Camprubí-Rimblas M, Tantinyà N, Bringué J, Guillamat-Prats R, Matthay MA. Inhalation therapies in acute respiratory distress syndrome. 2017. PMID: 28828368

  102. Kallet RH, Zhuo H, Ho K, Lipnick MS, Gomez A, Matthay MA. Lung Injury Etiology and Other Factors Influencing the Relationship Between Dead-Space Fraction and Mortality in ARDS. 2017. PMID: 28611227

  103. Zhao Z, Wickersham N, Kangelaris KN, May AK, Bernard GR, Matthay MA, Calfee CS, Koyama T, Ware LB. External validation of a biomarker and clinical prediction model for hospital mortality in acute respiratory distress syndrome. 2017. PMID: 28593401

  104. Chun LF, Moazed F, Calfee CS, Matthay MA, Gotts JE. Pulmonary toxicity of e-cigarettes. 2017. PMID: 28522559

  105. McAuley DF, Cross LM, Hamid U, Gardner E, Elborn JS, Cullen KM, Dushianthan A, Grocott MP, Matthay MA, O'Kane CM. Keratinocyte growth factor for the treatment of the acute respiratory distress syndrome (KARE): a randomised, double-blind, placebo-controlled phase 2 trial. 2017. PMID: 28526233

  106. Gattinoni L, Pesenti A, Matthay M. Understanding blood gas analysis. 2017. PMID: 28497267

  107. Roubinian NH, Looney MR, Keating S, Kor DJ, Lowell CA, Gajic O, Hubmayr R, Gropper M, Koenigsberg M, Wilson GA, A Matthay M, Toy P, Murphy EL. Differentiating pulmonary transfusion reactions using recipient and transfusion factors. 2017. PMID: 28470756

  108. Zinter MS, Orwoll BE, Spicer AC, Alkhouli MF, Calfee CS, Matthay MA, Sapru A. Incorporating Inflammation into Mortality Risk in Pediatric Acute Respiratory Distress Syndrome. 2017. PMID: 28248715

  109. Festic E, Carr GE, Cartin-Ceba R, Hinds RF, Banner-Goodspeed V, Bansal V, Asuni AT, Talmor D, Rajagopalan G, Frank RD, Gajic O, Matthay MA, Levitt JE. Randomized Clinical Trial of a Combination of an Inhaled Corticosteroid and Beta Agonist in Patients at Risk of Developing the Acute Respiratory Distress Syndrome. 2017. PMID: 28240689

  110. Leligdowicz A, Conroy AL, Hawkes M, Zhong K, Lebovic G, Matthay MA, Kain KC. Validation of two multiplex platforms to quantify circulating markers of inflammation and endothelial injury in severe infection. 2017. PMID: 28419100

  111. Rogers AJ, Contrepois K, Wu M, Zheng M, Peltz G, Ware LB, Matthay MA. Profiling of ARDS pulmonary edema fluid identifies a metabolically distinct subset. 2017. PMID: 28258106

  112. Hamilton BC, Kukreja J, Ware LB, Matthay MA. Protein biomarkers associated with primary graft dysfunction following lung transplantation. 2017. PMID: 28130262

  113. Roubinian NH, Hendrickson JE, Triulzi DJ, Gottschall JL, Chowdhury D, Kor DJ, Looney MR, Matthay MA, Kleinman SH, Brambilla D, Murphy EL. Incidence and clinical characteristics of transfusion-associated circulatory overload using an active surveillance algorithm. 2016. PMID: 28001313

  114. Bhatraju PK, Mukherjee P, Robinson-Cohen C, O'Keefe GE, Frank AJ, Christie JD, Meyer NJ, Liu KD, Matthay MA, Calfee CS, Christiani DC, Himmelfarb J, Wurfel MM. Acute kidney injury subphenotypes based on creatinine trajectory identifies patients at increased risk of death. 2016. PMID: 27852290

  115. Zemans RL, Matthay MA. What drives neutrophils to the alveoli in ARDS? 2016. PMID: 27974631

  116. Xu X, Greenland JR, Gotts JE, Matthay MA, Caughey GH. Cathepsin L Helps to Defend Mice from Infection with Influenza A. Volume 11 of Issue 10. 2016. PMID: 27716790

  117. Spicer AC, Calfee CS, Zinter MS, Khemani RG, Lo VP, Alkhouli MF, Orwoll BE, Graciano AL, Boriosi JP, Howard JP, Flori HR, Matthay MA, Sapru A. A Simple and Robust Bedside Model for Mortality Risk in Pediatric Patients With Acute Respiratory Distress Syndrome. 2016. PMID: 27487912

  118. Ward SL, Quinn CM, Valentine SL, Sapru A, Curley MA, Willson DF, Liu KD, Matthay MA, Flori HR. Poor Adherence to Lung-Protective Mechanical Ventilation in Pediatric Acute Respiratory Distress Syndrome. 2016. PMID: 27513687

  119. Gordon ED, Palandra J, Wesolowska-Andersen A, Ringel L, Rios CL, Lachowicz-Scroggins ME, Sharp LZ, Everman JL, MacLeod HJ, Lee JW, Mason RJ, Matthay MA, Sheldon RT, Peters MC, Nocka KH, Fahy JV, Seibold MA. IL1RL1 asthma risk variants regulate airway type 2 inflammation. 2016. PMID: 27699235

  120. Kangelaris KN, Ware LB, Matthay MA, Calfee CS. The authors reply. 2016. PMID: 27428148

  121. Kangelaris KN, Ware LB, Matthay MA, Calfee CS. The authors reply. 2016. PMID: 27428150

  122. Disayabutr S, Kim EK, Cha SI, Green G, Naikawadi RP, Jones KD, Golden JA, Schroeder A, Matthay MA, Kukreja J, Erle DJ, Collard HR, Wolters PJ. miR-34 miRNAs Regulate Cellular Senescence in Type II Alveolar Epithelial Cells of Patients with Idiopathic Pulmonary Fibrosis. Volume 11 of Issue 6. 2016. PMID: 27362652

  123. Beitler JR, Sands SA, Loring SH, Owens RL, Malhotra A, Spragg RG, Matthay MA, Thompson BT, Talmor D. Quantifying unintended exposure to high tidal volumes from breath stacking dyssynchrony in ARDS: the BREATHE criteria. 2016. PMID: 27342819

  124. Puig F, Herrero R, Guillamat-Prats R, Gómez MN, Tijero J, Chimenti L, Stelmakh O, Blanch L, Serrano-Mollar A, Matthay MA, Artigas A. A new experimental model of acid- and endotoxin-induced acute lung injury in rats. 2016. PMID: 27317688

  125. Hendrickson CM, Howard BM, Kornblith LZ, Conroy AS, Nelson MF, Zhuo H, Liu KD, Manley GT, Matthay MA, Calfee CS, Cohen MJ. The acute respiratory distress syndrome following isolated severe traumatic brain injury. 2016. PMID: 26881489

  126. Sapru A, Liu KD, Wiemels J, Hansen H, Pawlikowska L, Poon A, Jorgenson E, Witte JS, Calfee CS, Ware LB, Matthay MA. Association of common genetic variation in the protein C pathway genes with clinical outcomes in acute respiratory distress syndrome. 2016. PMID: 27215212

  127. Gotts JE, Matthay MA. Sepsis: pathophysiology and clinical management. 2016. PMID: 27217054

  128. Ware LB, Zhao Z, Koyama T, May AK, Matthay MA, Lurmann FW, Balmes JR, Calfee CS. Long-Term Ozone Exposure Increases the Risk of Developing the Acute Respiratory Distress Syndrome. Volume 193 of Issue 10. 2016. PMID: 26681363

  129. Jackson MV, Morrison TJ, Doherty DF, McAuley DF, Matthay MA, Kissenpfennig A, O'Kane CM, Krasnodembskaya AD. Mitochondrial Transfer via Tunneling Nanotubes is an Important Mechanism by Which Mesenchymal Stem Cells Enhance Macrophage Phagocytosis in the In Vitro and In Vivo Models of ARDS. 2016. PMID: 27059413

  130. Bhattacharya M, Kallet RH, Ware LB, Matthay MA. Negative-Pressure Pulmonary Edema. 2016. PMID: 27063348

  131. Vieillard-Baron A, Matthay M, Teboul JL, Bein T, Schultz M, Magder S, Marini JJ. Experts' opinion on management of hemodynamics in ARDS patients: focus on the effects of mechanical ventilation. 2016. PMID: 27038480

  132. Papazian L, Calfee CS, Chiumello D, Luyt CE, Meyer NJ, Sekiguchi H, Matthay MA, Meduri GU. Diagnostic workup for ARDS patients. 2016. PMID: 27007111

  133. Chan MC, Kuok DI, Leung CY, Hui KP, Valkenburg SA, Lau EH, Nicholls JM, Fang X, Guan Y, Lee JW, Chan RW, Webster RG, Matthay MA, Peiris JS. Human mesenchymal stromal cells reduce influenza A H5N1-associated acute lung injury in vitro and in vivo. 2016. PMID: 26976597

  134. Ernecoff NC, Witteman HO, Chon K, Chen YI, Buddadhumaruk P, Chiarchiaro J, Shotsberger KJ, Shields AM, Myers BA, Hough CL, Carson SS, Lo B, Matthay MA, Anderson WG, Peterson MW, Steingrub JS, Arnold RM, White DB. Key stakeholders' perceptions of the acceptability and usefulness of a tablet-based tool to improve communication and shared decision making in ICUs. 2016. PMID: 27037049

  135. Moazed F, Burnham EL, Vandivier RW, O'Kane CM, Shyamsundar M, Hamid U, Abbott J, Thickett DR, Matthay MA, McAuley DF, Calfee CS. Cigarette smokers have exaggerated alveolar barrier disruption in response to lipopolysaccharide inhalation. 2016. PMID: 26839359

  136. Guérin C, Matthay MA. Acute cor pulmonale and the acute respiratory distress syndrome. 2016. PMID: 26759013

  137. Kangelaris KN, Ware LB, Wang CY, Janz DR, Zhuo H, Matthay MA, Calfee CS. Timing of Intubation and Clinical Outcomes in Adults With Acute Respiratory Distress Syndrome. 2016. PMID: 26474112

  138. Orwoll BE, Spicer AC, Zinter MS, Alkhouli MF, Khemani RG, Flori HR, Neuhaus JM, Calfee CS, Matthay MA, Sapru A. Elevated soluble thrombomodulin is associated with organ failure and mortality in children with acute respiratory distress syndrome (ARDS): a prospective observational cohort study. 2015. PMID: 26652251

  139. Zinter MS, Spicer A, Orwoll BO, Alkhouli M, Dvorak CC, Calfee CS, Matthay MA, Sapru A. Plasma angiopoietin-2 outperforms other markers of endothelial injury in prognosticating pediatric ARDS mortality. 2015. PMID: 26660787

  140. Calfee CS, Matthay MA, Kangelaris KN, Siew ED, Janz DR, Bernard GR, May AK, Jacob P, Havel C, Benowitz NL, Ware LB. Cigarette Smoke Exposure and the Acute Respiratory Distress Syndrome. 2015. PMID: 26010690

  141. Monsel A, Zhu YG, Gennai S, Hao Q, Hu S, Rouby JJ, Rosenzwajg M, Matthay MA, Lee JW. Therapeutic Effects of Human Mesenchymal Stem Cell-derived Microvesicles in Severe Pneumonia in Mice. 2015. PMID: 26067592

  142. Fang X, Abbott J, Cheng L, Colby JK, Lee JW, Levy BD, Matthay MA. Human Mesenchymal Stem (Stromal) Cells Promote the Resolution of Acute Lung Injury in Part through Lipoxin A4. 2015. PMID: 26116507

  143. Rajasekaran S, Tamatam CR, Potteti HR, Raman V, Lee JW, Matthay MA, Mehta D, Reddy NM, Reddy SP. Visualization of Fra-1/AP-1 activation during LPS-induced inflammatory lung injury using fluorescence optical imaging. 2015. PMID: 26071555

  144. Calfee CS, Janz DR, Bernard GR, May AK, Kangelaris KN, Matthay MA, Ware LB. Distinct molecular phenotypes of direct vs indirect ARDS in single-center and multicenter studies. 2015. PMID: 26033126

  145. Li JT, Melton AC, Su G, Hamm DE, LaFemina M, Howard J, Fang X, Bhat S, Huynh KM, O'Kane CM, Ingram RJ, Muir RR, McAuley DF, Matthay MA, Sheppard D. Unexpected Role for Adaptive aßTh17 Cells in Acute Respiratory Distress Syndrome. Volume 195 of Issue 1. 2015. PMID: 26002979

  146. Matthay MA. Saving lives with high-flow nasal oxygen. 2015. PMID: 25982042

  147. Curley MA, Wypij D, Matthay MA. Sedation protocol for critically ill pediatric patients--reply. 2015. PMID: 25942731

  148. Beitler JR, Thompson BT, Matthay MA, Talmor D, Liu KD, Zhuo H, Hayden D, Spragg RG, Malhotra A. Estimating dead-space fraction for secondary analyses of acute respiratory distress syndrome clinical trials. 2015. PMID: 25738857

  149. Kangelaris KN, Prakash A, Liu KD, Aouizerat B, Woodruff PG, Erle DJ, Rogers A, Seeley EJ, Chu J, Liu T, Osterberg-Deiss T, Zhuo H, Matthay MA, Calfee CS. Increased expression of neutrophil-related genes in patients with early sepsis-induced ARDS. Volume 308 of Issue 11. 2015. PMID: 25795726

  150. Sapru A, Calfee CS, Liu KD, Kangelaris K, Hansen H, Pawlikowska L, Ware LB, Alkhouli MF, Abbott J, Matthay MA. Erratum to: plasma soluble thrombomodulin levels are associated with mortality in the acute respiratory distress syndrome. 2015. PMID: 25708422

  151. Roubinian NH, Looney MR, Kor DJ, Lowell CA, Gajic O, Hubmayr RD, Gropper MA, Koenigsberg M, Wilson GA, Matthay MA, Toy P, Murphy EL. Cytokines and clinical predictors in distinguishing pulmonary transfusion reactions. 2015. PMID: 25702590

  152. Sapru A, Calfee CS, Liu KD, Kangelaris K, Hansen H, Pawlikowska L, Ware LB, Alkhouli MF, Abbott J, Abbot J, Matthay MA. Plasma soluble thrombomodulin levels are associated with mortality in the acute respiratory distress syndrome. 2015. PMID: 25643902

  153. Anderson WG, Cimino JW, Ernecoff NC, Ungar A, Shotsberger KJ, Pollice LA, Buddadhumaruk P, Carson SS, Curtis JR, Hough CL, Lo B, Matthay MA, Peterson MW, Steingrub JS, White DB. A multicenter study of key stakeholders' perspectives on communicating with surrogates about prognosis in intensive care units. 2015. PMID: 25521191

  154. Curley MA, Wypij D, Watson RS, Grant MJ, Asaro LA, Cheifetz IM, Dodson BL, Franck LS, Gedeit RG, Angus DC, Matthay MA. Protocolized sedation vs usual care in pediatric patients mechanically ventilated for acute respiratory failure: a randomized clinical trial. 2015. PMID: 25602358

  155. Ji HL, Zhao R, Komissarov AA, Chang Y, Liu Y, Matthay MA. Proteolytic regulation of epithelial sodium channels by urokinase plasminogen activator: cutting edge and cleavage sites. 2015. PMID: 25555911

  156. Schell-Chaple HM, Puntillo KA, Matthay MA, Liu KD. Body temperature and mortality in patients with acute respiratory distress syndrome. 2015. PMID: 25554550

  157. Vaughan AE, Brumwell AN, Xi Y, Gotts JE, Brownfield DG, Treutlein B, Tan K, Tan V, Liu FC, Looney MR, Matthay MA, Rock JR, Chapman HA. Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury. 2014. PMID: 25533958

  158. Wilson JG, Liu KD, Zhuo H, Caballero L, McMillan M, Fang X, Cosgrove K, Vojnik R, Calfee CS, Lee JW, Rogers AJ, Levitt J, Wiener-Kronish J, Bajwa EK, Leavitt A, McKenna D, Thompson BT, Matthay MA. Mesenchymal stem (stromal) cells for treatment of ARDS: a phase 1 clinical trial. Volume 3 of Issue 1. 2014. PMID: 25529339

  159. Toy P, Bacchetti P, Grimes B, Gajic O, Murphy EL, Winters JL, Gropper MA, Hubmayr RD, Matthay MA, Wilson G, Koenigsberg M, Lee DC, Hirschler NV, Lowell CA, Schuller RM, Gandhi MJ, Norris PJ, Mair DC, Sanchez Rosen R, Looney MR. Recipient clinical risk factors predominate in possible transfusion-related acute lung injury. 2014. PMID: 25488517

  160. Hendrickson CM, Crestani B, Matthay MA. Biology and pathology of fibroproliferation following the acute respiratory distress syndrome. 2014. PMID: 25480350

  161. DePianto DJ, Chandriani S, Abbas AR, Jia G, N'Diaye EN, Caplazi P, Kauder SE, Biswas S, Karnik SK, Ha C, Modrusan Z, Matthay MA, Kukreja J, Collard HR, Egen JG, Wolters PJ, Arron JR. Heterogeneous gene expression signatures correspond to distinct lung pathologies and biomarkers of disease severity in idiopathic pulmonary fibrosis. 2014. PMID: 25217476

  162. Czikora I, Alli A, Bao HF, Kaftan D, Sridhar S, Apell HJ, Gorshkov B, White R, Zimmermann A, Wendel A, Pauly-Evers M, Hamacher J, Garcia-Gabay I, Fischer B, Verin A, Bagi Z, Pittet JF, Shabbir W, Lemmens-Gruber R, Chakraborty T, Lazrak A, Matthay MA, Eaton DC, Lucas R. A novel tumor necrosis factor-mediated mechanism of direct epithelial sodium channel activation. 2014. PMID: 25029038

  163. Hsieh SJ, Zhuo H, Benowitz NL, Thompson BT, Liu KD, Matthay MA, Calfee CS. Prevalence and impact of active and passive cigarette smoking in acute respiratory distress syndrome. 2014. PMID: 24942512

  164. Fitzgerald M, McAuley DF, Matthay M. Is there a need for emerging drugs for the acute respiratory distress syndrome? 2014. PMID: 25152048

  165. Ware LB, Lee JW, Wickersham N, Nguyen J, Matthay MA, Calfee CS. Donor smoking is associated with pulmonary edema, inflammation and epithelial dysfunction in ex vivo human donor lungs. 2014. PMID: 25146497

  166. Krupa A, Fol M, Rahman M, Stokes KY, Florence JM, Leskov IL, Khoretonenko MV, Matthay MA, Liu KD, Calfee CS, Tvinnereim A, Rosenfield GR, Kurdowska AK. Silencing Bruton's tyrosine kinase in alveolar neutrophils protects mice from LPS/immune complex-induced acute lung injury. 2014. PMID: 25085625

  167. Czikora I, Sridhar S, Gorshkov B, Alieva IB, Kasa A, Gonzales J, Potapenko O, Umapathy NS, Pillich H, Rick FG, Block NL, Verin AD, Chakraborty T, Matthay MA, Schally AV, Lucas R. Protective effect of Growth Hormone-Releasing Hormone agonist in bacterial toxin-induced pulmonary barrier dysfunction. 2014. PMID: 25076911

  168. Liu KD, Wilson JG, Zhuo H, Caballero L, McMillan ML, Fang X, Cosgrove K, Calfee CS, Lee JW, Kangelaris KN, Gotts JE, Rogers AJ, Levitt JE, Wiener-Kronish JP, Delucchi KL, Leavitt AD, McKenna DH, Thompson BT, Matthay MA. Design and implementation of the START (STem cells for ARDS Treatment) trial, a phase 1/2 trial of human mesenchymal stem/stromal cells for the treatment of moderate-severe acute respiratory distress syndrome. Volume 4. 2014. PMID: 25593740

  169. Looney MR, Roubinian N, Gajic O, Gropper MA, Hubmayr RD, Lowell CA, Bacchetti P, Wilson G, Koenigsberg M, Lee DC, Wu P, Grimes B, Norris PJ, Murphy EL, Gandhi MJ, Winters JL, Mair DC, Schuller RM, Hirschler NV, Rosen RS, Matthay MA, Toy P. Prospective study on the clinical course and outcomes in transfusion-related acute lung injury*. 2014. PMID: 24776608

  170. Sakuma T, Matthay MA. Translational studies in the ex vivo human lung. 2014. PMID: 24998367

  171. Shyamsundar M, McAuley DF, Ingram RJ, Gibson DS, O'Kane D, McKeown ST, Edwards A, Taggart C, Elborn JS, Calfee CS, Matthay MA, O'Kane CM. Keratinocyte growth factor promotes epithelial survival and resolution in a human model of lung injury. 2014. PMID: 24716610

  172. Greer AM, Matthay MA, Kukreja J, Bhakta NR, Nguyen CP, Wolters PJ, Woodruff PG, Fahy JV, Shin JS. Accumulation of BDCA1? dendritic cells in interstitial fibrotic lung diseases and Th2-high asthma. 2014. PMID: 24915147

  173. Asmussen S, Ito H, Traber DL, Lee JW, Cox RA, Hawkins HK, McAuley DF, McKenna DH, Traber LD, Zhuo H, Wilson J, Herndon DN, Prough DS, Liu KD, Matthay MA, Enkhbaatar P. Human mesenchymal stem cells reduce the severity of acute lung injury in a sheep model of bacterial pneumonia. 2014. PMID: 24891325

  174. Calfee CS, Delucchi K, Parsons PE, Thompson BT, Ware LB, Matthay MA. Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials. 2014. PMID: 24853585

  175. Truwit JD, Bernard GR, Steingrub J, Matthay MA, Liu KD, Albertson TE, Brower RG, Shanholtz C, Rock P, Douglas IS, deBoisblanc BP, Hough CL, Hite RD, Thompson BT. Rosuvastatin for sepsis-associated acute respiratory distress syndrome. 2014. PMID: 24835849

  176. Rogers AJ, Matthay MA. Applying metabolomics to uncover novel biology in ARDS. 2014. PMID: 24727586

  177. Goolaerts A, Pellan-Randrianarison N, Larghero J, Vanneaux V, Uzunhan Y, Gille T, Dard N, Planès C, Matthay MA, Clerici C. Conditioned media from mesenchymal stromal cells restore sodium transport and preserve epithelial permeability in an in vitro model of acute alveolar injury. 2014. PMID: 24682451

  178. Ware LB, Landeck M, Koyama T, Zhao Z, Singer J, Kern R, Neidlinger N, Nguyen J, Johnson E, Janz DR, Bernard GR, Lee JW, Matthay MA. A randomized trial of the effects of nebulized albuterol on pulmonary edema in brain-dead organ donors. 2014. PMID: 24730050

  179. Kangelaris KN, Calfee CS, May AK, Zhuo H, Matthay MA, Ware LB. Is there still a role for the lung injury score in the era of the Berlin definition ARDS? 2014. PMID: 24533450

  180. McAuley DF, Curley GF, Hamid UI, Laffey JG, Abbott J, McKenna DH, Fang X, Matthay MA, Lee JW. Clinical grade allogeneic human mesenchymal stem cells restore alveolar fluid clearance in human lungs rejected for transplantation. 2014. PMID: 24532289

  181. Liles WC, Matthay MA, Dos Santos CC, Weiss DJ, Stewart DJ. Mesenchymal stromal (stem) cell therapy: an emerging immunomodulatory strategy for the adjunctive treatment of sepsis. 2014. PMID: 24484339

  182. Rogers AJ, McGeachie M, Baron RM, Gazourian L, Haspel JA, Nakahira K, Fredenburgh LE, Hunninghake GM, Raby BA, Matthay MA, Otero RM, Fowler VG, Rivers EP, Woods CW, Kingsmore S, Langley RJ, Choi AM. Metabolomic derangements are associated with mortality in critically ill adult patients. 2014. PMID: 24498130

  183. Wang CY, Calfee CS, Paul DW, Janz DR, May AK, Zhuo H, Bernard GR, Matthay MA, Ware LB, Kangelaris KN. One-year mortality and predictors of death among hospital survivors of acute respiratory distress syndrome. 2014. PMID: 24435201

  184. Frank JA, Matthay MA. TGF-ß and lung fluid balance in ARDS. Volume 111 of Issue 3. 2014. PMID: 24449829

  185. Shyamsundar M, McAuley DF, Shields MO, MacSweeney R, Duffy MJ, Johnston JR, McGuigan J, Backman JT, Calfee CS, Matthay MM, Griffiths MJ, McDowell C, Elborn SJ, O'Kane CM. Effect of simvastatin on physiological and biological outcomes in patients undergoing esophagectomy: a randomized placebo-controlled trial. 2014. PMID: 23817506

  186. Zhu YG, Feng XM, Abbott J, Fang XH, Hao Q, Monsel A, Qu JM, Matthay MA, Lee JW. Human mesenchymal stem cell microvesicles for treatment of Escherichia coli endotoxin-induced acute lung injury in mice. 2014. PMID: 23939814

  187. Gotts JE, Matthay MA. Treating ARDS: new hope for a tough problem. 2013. PMID: 24503258

  188. Engel J, Matthay M. Cystic fibrosis epithelial cell and bacterial binding. 2013. PMID: 24310120

  189. Bajwa EK, Volk JA, Christiani DC, Harris RS, Matthay MA, Thompson BT, Januzzi JL. Prognostic and diagnostic value of plasma soluble suppression of tumorigenicity-2 concentrations in acute respiratory distress syndrome. 2013. PMID: 23939353

  190. Ware LB, Koyama T, Zhao Z, Janz DR, Wickersham N, Bernard GR, May AK, Calfee CS, Matthay MA. Biomarkers of lung epithelial injury and inflammation distinguish severe sepsis patients with acute respiratory distress syndrome. 2013. PMID: 24156650

  191. Vieillard-Baron A, Price LC, Matthay MA. Acute cor pulmonale in ARDS. 2013. PMID: 23907498

  192. Matthay MA, Anversa P, Bhattacharya J, Burnett BK, Chapman HA, Hare JM, Hei DJ, Hoffman AM, Kourembanas S, McKenna DH, Ortiz LA, Ott HC, Tente W, Thébaud B, Trapnell BC, Weiss DJ, Yuan JX, Blaisdell CJ. Cell therapy for lung diseases. Report from an NIH-NHLBI workshop, November 13-14, 2012. 2013. PMID: 23713908

  193. Levitt JE, Calfee CS, Goldstein BA, Vojnik R, Matthay MA. Early acute lung injury: criteria for identifying lung injury prior to the need for positive pressure ventilation*. 2013. PMID: 23782966

  194. Toonkel RL, Hare JM, Matthay MA, Glassberg MK. Mesenchymal stem cells and idiopathic pulmonary fibrosis. Potential for clinical testing. 2013. PMID: 23306542

  195. Glassberg MK, Hare JM, Toonkel RL, Matthay MA. Reply: idiopathic pulmonary fibrosis: a degenerative disease requiring a regenerative approach. 2013. PMID: 23855697

  196. Bucior I, Abbott J, Song Y, Matthay MA, Engel JN. Sugar administration is an effective adjunctive therapy in the treatment of Pseudomonas aeruginosa pneumonia. 2013. PMID: 23792737

  197. Gotts JE, Matthay MA. Cell therapy for lung disease: a step forward. 2013. PMID: 23732575

  198. Matthay MA, Song Y, Bai C, Jones KD. The acute respiratory distress syndrome in 2013. 2013. PMID: 27234392

  199. Pittet JF, Koh H, Fang X, Iles K, Christiaans S, Anjun N, Wagener BM, Park DW, Zmijewski JW, Matthay MA, Roux J. HMGB1 accelerates alveolar epithelial repair via an IL-1ß- and avß6 integrin-dependent activation of TGF-ß1. 2013. PMID: 23696858

  200. Agrawal A, Matthay MA, Kangelaris KN, Stein J, Chu JC, Imp BM, Cortez A, Abbott J, Liu KD, Calfee CS. Plasma angiopoietin-2 predicts the onset of acute lung injury in critically ill patients. 2013. PMID: 23328529

  201. Katsumoto TR, Kudo M, Chen C, Sundaram A, Callahan EC, Zhu JW, Lin J, Rosen CE, Manz BN, Lee JW, Matthay MA, Huang X, Sheppard D, Weiss A. The phosphatase CD148 promotes airway hyperresponsiveness through SRC family kinases. Volume 123 of Issue 5. 2013. PMID: 23543053

  202. Lee JW, Krasnodembskaya A, McKenna DH, Song Y, Abbott J, Matthay MA. Therapeutic effects of human mesenchymal stem cells in ex vivo human lungs injured with live bacteria. 2013. PMID: 23292883

  203. Seeley EJ, Barry SS, Narala S, Matthay MA, Wolters PJ. Noradrenergic neurons regulate monocyte trafficking and mortality during gram-negative peritonitis in mice. 2013. PMID: 23543756

  204. Su X, Feng X, Terrando N, Yan Y, Chawla A, Koch LG, Britton SL, Matthay MA, Maze M. Dysfunction of inflammation-resolving pathways is associated with exaggerated postoperative cognitive decline in a rat model of the metabolic syndrome. 2013. PMID: 23296426

  205. Howard M, Roux J, Iles KE, Miyazawa B, Christiaans S, Anjum N, Dickinson DA, Goolaerts A, Matthay MA, Pittet JF. Activation of the heat shock response attenuates the interleukin 1ß-mediated inhibition of the amiloride-sensitive alveolar epithelial ion transport. 2013. PMID: 23324889

  206. Murphy EL, Kwaan N, Looney MR, Gajic O, Hubmayr RD, Gropper MA, Koenigsberg M, Wilson G, Matthay M, Bacchetti P, Toy P. Risk factors and outcomes in transfusion-associated circulatory overload. 2013. PMID: 23357450

  207. Bastarache JA, Matthay MA. Cecal ligation model of sepsis in mice: new insights. 2013. PMID: 23269150

  208. Kallet RH, Matthay MA. Hyperoxic acute lung injury. 2013. PMID: 23271823

  209. Roux J, McNicholas CM, Carles M, Goolaerts A, Houseman BT, Dickinson DA, Iles KE, Ware LB, Matthay MA, Pittet JF. IL-8 inhibits cAMP-stimulated alveolar epithelial fluid transport via a GRK2/PI3K-dependent mechanism. 2012. PMID: 23221335

  210. Komissarov AA, Stankowska D, Krupa A, Fudala R, Florova G, Florence J, Fol M, Allen TC, Idell S, Matthay MA, Kurdowska AK. Novel aspects of urokinase function in the injured lung: role of a2-macroglobulin. 2012. PMID: 23064953

  211. Khush KK, Pawlikowska L, Menza RL, Goldstein BA, Hayden V, Nguyen J, Kim H, Poon A, Sapru A, Matthay MA, Kwok PY, Young WL, Baxter-Lowe LA, Zaroff JG. Beta-adrenergic receptor polymorphisms and cardiac graft function in potential organ donors. 2012. PMID: 22994654

  212. Agrawal A, Zhuo H, Brady S, Levitt J, Steingrub J, Siegel MD, Soto G, Peterson MW, Chesnutt MS, Matthay MA, Liu KD. Pathogenetic and predictive value of biomarkers in patients with ALI and lower severity of illness: results from two clinical trials. 2012. PMID: 22865551

  213. Matthay MA, Ware LB, Zimmerman GA. The acute respiratory distress syndrome. 2012. PMID: 22850883

  214. Rackley CR, Levitt JE, Zhuo H, Matthay MA, Calfee CS. Clinical evidence of early acute lung injury often precedes the diagnosis of ALI. 2012. PMID: 22733725

  215. Seeley EJ, Matthay MA, Wolters PJ. Inflection points in sepsis biology: from local defense to systemic organ injury. 2012. PMID: 22707617

  216. Lee JW, Zhu Y, Matthay MA. Cell-based therapy for acute lung injury: are we there yet? 2012. PMID: 22531337

  217. Calfee CS, Gallagher D, Abbott J, Thompson BT, Matthay MA. Plasma angiopoietin-2 in clinical acute lung injury: prognostic and pathogenetic significance. 2012. PMID: 22610178

  218. Folkesson HG, Kuzenko SR, Lipson DA, Matthay MA, Simmons MA. The adenosine 2A receptor agonist GW328267C improves lung function after acute lung injury in rats. 2012. PMID: 22659881

  219. Lucas R, Yang G, Gorshkov BA, Zemskov EA, Sridhar S, Umapathy NS, Jezierska-Drutel A, Alieva IB, Leustik M, Hossain H, Fischer B, Catravas JD, Verin AD, Pittet JF, Caldwell RB, Mitchell TJ, Cederbaum SD, Fulton DJ, Matthay MA, Caldwell RW, Romero MJ, Chakraborty T. Protein kinase C-a and arginase I mediate pneumolysin-induced pulmonary endothelial hyperpermeability. 2012. PMID: 22582175

  220. Nazarov I, Lee JW, Soupene E, Etemad S, Knapik D, Green W, Bashkirova E, Fang X, Matthay MA, Kuypers FA, Serikov VB. Multipotent stromal stem cells from human placenta demonstrate high therapeutic potential. 2012. PMID: 23197815

  221. Bhattacharya M, Su G, Su X, Oses-Prieto JA, Li JT, Huang X, Hernandez H, Atakilit A, Burlingame AL, Matthay MA, Sheppard D. IQGAP1 is necessary for pulmonary vascular barrier protection in murine acute lung injury and pneumonia. Volume 303 of Issue 1. 2012. PMID: 22561460

  222. Gotts JE, Matthay MA. Mesenchymal stem cells and the stem cell niche: a new chapter. 2012. PMID: 22505672

  223. Krasnodembskaya A, Samarani G, Song Y, Zhuo H, Su X, Lee JW, Gupta N, Petrini M, Matthay MA. Human mesenchymal stem cells reduce mortality and bacteremia in gram-negative sepsis in mice in part by enhancing the phagocytic activity of blood monocytes. 2012. PMID: 22427530

  224. Cha SI, Chang CS, Kim EK, Lee JW, Matthay MA, Golden JA, Elicker BM, Jones K, Collard HR, Wolters PJ. Lung mast cell density defines a subpopulation of patients with idiopathic pulmonary fibrosis. 2012. PMID: 22394225

  225. Sapru A, Zaroff JG, Pawlikowska L, Liu KD, Khush KK, Baxter-Lowe LA, Hayden V, Menza RL, Convery M, Lo V, Poon A, Kim H, Young WL, Kukreja J, Matthay MA. The 4G/4G genotype of the PAI-1 (serpine-1) 4G/5G polymorphism is associated with decreased lung allograft utilization. 2012. PMID: 22390401

  226. Ware LB, Neyrinck A, O'Neal HR, Lee JW, Landeck M, Johnson E, Calfee CS, Matthay MA. Comparison of chest radiograph scoring to lung weight as a quantitative index of pulmonary edema in organ donors. 2012. PMID: 22324977

  227. Bosmann M, Grailer JJ, Zhu K, Matthay MA, Sarma JV, Zetoune FS, Ward PA. Anti-inflammatory effects of ß2 adrenergic receptor agonists in experimental acute lung injury. 2012. PMID: 22318967

  228. Christie JD, Wurfel MM, Feng R, O'Keefe GE, Bradfield J, Ware LB, Christiani DC, Calfee CS, Cohen MJ, Matthay M, Meyer NJ, Kim C, Li M, Akey J, Barnes KC, Sevransky J, Lanken PN, May AK, Aplenc R, Maloney JP, Hakonarson H. Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma. 2012. PMID: 22295056

  229. Lucas R, Sridhar S, Rick FG, Gorshkov B, Umapathy NS, Yang G, Oseghale A, Verin AD, Chakraborty T, Matthay MA, Zemskov EA, White R, Block NL, Schally AV. Agonist of growth hormone-releasing hormone reduces pneumolysin-induced pulmonary permeability edema. 2012. PMID: 22308467

  230. Gupta N, Krasnodembskaya A, Kapetanaki M, Mouded M, Tan X, Serikov V, Matthay MA. Mesenchymal stem cells enhance survival and bacterial clearance in murine Escherichia coli pneumonia. 2012. PMID: 22250097

  231. Datar SA, Johnson EG, Oishi PE, Johengen M, Tang E, Aramburo A, Barton J, Kuo HC, Bennett S, Xoinis K, Reel B, Kalkan G, Sajti E, Osorio O, Raff GW, Matthay MA, Fineman JR. Altered lymphatics in an ovine model of congenital heart disease with increased pulmonary blood flow. 2011. PMID: 22207591

  232. Kangelaris KN, Sapru A, Calfee CS, Liu KD, Pawlikowska L, Witte JS, Vittinghoff E, Zhuo H, Auerbach AD, Ziv E, Matthay MA. The association between a Darc gene polymorphism and clinical outcomes in African American patients with acute lung injury. Volume 141 of Issue 5. 2011. PMID: 22207676

  233. Brown LM, Calfee CS, Matthay MA, Brower RG, Thompson BT, Checkley W. A simple classification model for hospital mortality in patients with acute lung injury managed with lung protective ventilation. 2011. PMID: 21725235

  234. Liu KD, Thompson BT, Ancukiewicz M, Steingrub JS, Douglas IS, Matthay MA, Wright P, Peterson MW, Rock P, Hyzy RC, Anzueto A, Truwit JD. Acute kidney injury in patients with acute lung injury: impact of fluid accumulation on classification of acute kidney injury and associated outcomes. 2011. PMID: 21785346

  235. Toy P, Gajic O, Bacchetti P, Looney MR, Gropper MA, Hubmayr R, Lowell CA, Norris PJ, Murphy EL, Weiskopf RB, Wilson G, Koenigsberg M, Lee D, Schuller R, Wu P, Grimes B, Gandhi MJ, Winters JL, Mair D, Hirschler N, Sanchez Rosen R, Matthay MA. Transfusion-related acute lung injury: incidence and risk factors. 2011. PMID: 22117051

  236. Mac Sweeney R, McAuley DF, Matthay MA. Acute lung failure. 2011. PMID: 21989697

  237. Matthay MA, Brower RG, Carson S, Douglas IS, Eisner M, Hite D, Holets S, Kallet RH, Liu KD, MacIntyre N, Moss M, Schoenfeld D, Steingrub J, Thompson BT. Randomized, placebo-controlled clinical trial of an aerosolized ß2-agonist for treatment of acute lung injury. 2011. PMID: 21562125

  238. Pitt BR, Christman JW, Gunst SJ, Matthay MA, Stevens T, Ware LB. Physiology, reductionism, and translational medicine: the right mix. 2011. PMID: 21856812

  239. Rokkam D, Lafemina MJ, Lee JW, Matthay MA, Frank JA. Claudin-4 levels are associated with intact alveolar fluid clearance in human lungs. Volume 179 of Issue 3. 2011. PMID: 21741940

  240. Ware LB, Koyama T, Billheimer D, Landeck M, Johnson E, Brady S, Bernard GR, Matthay MA. Advancing donor management research: design and implementation of a large, randomized, placebo-controlled trial. 2011. PMID: 21906362

  241. Lee JW, Fang X, Krasnodembskaya A, Howard JP, Matthay MA. Concise review: Mesenchymal stem cells for acute lung injury: role of paracrine soluble factors. 2011. PMID: 21506195

  242. Gotts JE, Matthay MA. Mesenchymal stem cells and acute lung injury. 2011. PMID: 21742225

  243. Matute-Bello G, Downey G, Moore BB, Groshong SD, Matthay MA, Slutsky AS, Kuebler WM. An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animals. 2011. PMID: 21531958

  244. Marmai C, Sutherland RE, Kim KK, Dolganov GM, Fang X, Kim SS, Jiang S, Golden JA, Hoopes CW, Matthay MA, Chapman HA, Wolters PJ. Alveolar epithelial cells express mesenchymal proteins in patients with idiopathic pulmonary fibrosis. 2011. PMID: 21498628

  245. Calfee CS, Ware LB, Glidden DV, Eisner MD, Parsons PE, Thompson BT, Matthay MA. Use of risk reclassification with multiple biomarkers improves mortality prediction in acute lung injury. 2011. PMID: 21283009

  246. Calfee CS, Matthay MA, Eisner MD, Benowitz N, Call M, Pittet JF, Cohen MJ. Active and passive cigarette smoking and acute lung injury after severe blunt trauma. 2011. PMID: 21471091

  247. Rice TW, Ware LB, Haponik EF, Chiles C, Wheeler AP, Bernard GR, Steingrub JS, Hite RD, Matthay MA, Wright P, Ely EW. Vascular pedicle width in acute lung injury: correlation with intravascular pressures and ability to discriminate fluid status. 2011. PMID: 21385351

  248. Su X, Looney MR, Su HE, Lee JW, Song Y, Matthay MA. Role of CFTR expressed by neutrophils in modulating acute lung inflammation and injury in mice. 2011. PMID: 21301926

  249. Rey MM, Ware LB, Matthay MA, Bernard GR, McGuire AL, Caplan AL, Halpern SD. Informed consent in research to improve the number and quality of deceased donor organs. 2011. PMID: 20975549

  250. Sapru A, Pawlikowska L, Liu KD, Khush KK, Ann-Baxter-Lowe L, Hayden V, Menza RL, Convery M, Poon A, Landeck M, Zaroff JG, Matthay MA. Single-nucleotide polymorphisms in the ß-adrenergic receptor genes are associated with lung allograft utilization. 2011. PMID: 20869266

  251. Finigan JH, Faress JA, Wilkinson E, Mishra RS, Nethery DE, Wyler D, Shatat M, Ware LB, Matthay MA, Mason R, Silver RF, Kern JA. Neuregulin-1-human epidermal receptor-2 signaling is a central regulator of pulmonary epithelial permeability and acute lung injury. 2011. PMID: 21247898

  252. Hsieh SJ, Ware LB, Eisner MD, Yu L, Jacob P, Havel C, Goniewicz ML, Matthay MA, Benowitz NL, Calfee CS. Biomarkers increase detection of active smoking and secondhand smoke exposure in critically ill patients. 2011. PMID: 20935560

  253. Matthay MA, Zemans RL. The acute respiratory distress syndrome: pathogenesis and treatment. 2011. PMID: 20936936

  254. Krasnodembskaya A, Song Y, Fang X, Gupta N, Serikov V, Lee JW, Matthay MA. Antibacterial effect of human mesenchymal stem cells is mediated in part from secretion of the antimicrobial peptide LL-37. 2010. PMID: 20945332

  255. Cribbs SK, Matthay MA, Martin GS. Stem cells in sepsis and acute lung injury. 2010. PMID: 20838330

  256. Matthay MA, Goolaerts A, Howard JP, Lee JW. Mesenchymal stem cells for acute lung injury: preclinical evidence. 2010. PMID: 21164399

  257. Matthay MA, Thompson BT, Read EJ, McKenna DH, Liu KD, Calfee CS, Lee JW. Therapeutic potential of mesenchymal stem cells for severe acute lung injury. 2010. PMID: 20923800

  258. Singer M, Matthay MA. Thinking outside the box: Introduction. 2010. PMID: 21164389

  259. Brown LM, Kallet RH, Matthay MA, Dicker RA. The influence of race on the development of acute lung injury in trauma patients. 2010. PMID: 20832050

  260. Looney MR, Gilliss BM, Matthay MA. Pathophysiology of transfusion-related acute lung injury. 2010. PMID: 20601870

  261. Ong T, McClintock DE, Kallet RH, Ware LB, Matthay MA, Liu KD. Ratio of angiopoietin-2 to angiopoietin-1 as a predictor of mortality in acute lung injury patients. 2010. PMID: 20581666

  262. McAuley DF, Brown LM, Matthay MA. Assessing the quantity of pulmonary edema in critically ill children. 2010. PMID: 20804574

  263. Bastarache JA, Ong T, Matthay MA, Ware LB. Alveolar fluid clearance is faster in women with acute lung injury compared to men. 2010. PMID: 20688464

  264. Johnson ER, Matthay MA. Acute lung injury: epidemiology, pathogenesis, and treatment. 2010. PMID: 20073554

  265. Diaz JV, Brower R, Calfee CS, Matthay MA. Therapeutic strategies for severe acute lung injury. 2010. PMID: 20562704

  266. Cooke CR, Erickson SE, Watkins TR, Matthay MA, Hudson LD, Rubenfeld GD. Age-, sex-, and race-based differences among patients enrolled versus not enrolled in acute lung injury clinical trials. 2010. PMID: 20386308

  267. Calfee CS, Thompson BT, Parsons PE, Ware LB, Matthay MA, Wong HR. Plasma interleukin-8 is not an effective risk stratification tool for adults with vasopressor-dependent septic shock. 2010. PMID: 20386309

  268. Matthay MA, Idell S. Update on acute lung injury and critical care medicine 2009. 2010. PMID: 20460547

  269. Fremont RD, Koyama T, Calfee CS, Wu W, Dossett LA, Bossert FR, Mitchell D, Wickersham N, Bernard GR, Matthay MA, May AK, Ware LB. Acute lung injury in patients with traumatic injuries: utility of a panel of biomarkers for diagnosis and pathogenesis. 2010. PMID: 20038857

  270. Collard HR, Calfee CS, Wolters PJ, Song JW, Hong SB, Brady S, Ishizaka A, Jones KD, King TE, Matthay MA, Kim DS. Plasma biomarker profiles in acute exacerbation of idiopathic pulmonary fibrosis. Volume 299 of Issue 1. 2010. PMID: 20418386

  271. Ballard PL, Lee JW, Fang X, Chapin C, Allen L, Segal MR, Fischer H, Illek B, Gonzales LW, Kolla V, Matthay MA. Regulated gene expression in cultured type II cells of adult human lung. 2010. PMID: 20382749

  272. Howard M, Roux J, Lee H, Miyazawa B, Lee JW, Gartland B, Howard AJ, Matthay MA, Carles M, Pittet JF. Activation of the stress protein response inhibits the STAT1 signalling pathway and iNOS function in alveolar macrophages: role of Hsp90 and Hsp70. 2010. PMID: 20388761

  273. Kim SH, Matthay MA, Mostov K, Hunt CA. Simulation of lung alveolar epithelial wound healing in vitro. 2010. PMID: 20236957

  274. Diep BA, Chan L, Tattevin P, Kajikawa O, Martin TR, Basuino L, Mai TT, Marbach H, Braughton KR, Whitney AR, Gardner DJ, Fan X, Tseng CW, Liu GY, Badiou C, Etienne J, Lina G, Matthay MA, DeLeo FR, Chambers HF. Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury. Volume 107 of Issue 12. 2010. PMID: 20231457

  275. Calfee CS, Matthay MA. Clinical immunology: Culprits with evolutionary ties. 2010. PMID: 20203598

  276. Brown LM, Matthay MA. Measuring the quantity of pulmonary edema in clinical lung injury. 2010. PMID: 20023478

  277. Vincent JL, Singer M, Marini JJ, Moreno R, Levy M, Matthay MA, Pinsky M, Rhodes A, Ferguson ND, Evans T, Annane D, Hall JB. Thirty years of critical care medicine. 2010. PMID: 20550727

  278. Roux J, Carles M, Koh H, Goolaerts A, Ganter MT, Chesebro BB, Howard M, Houseman BT, Finkbeiner W, Shokat KM, Paquet AC, Matthay MA, Pittet JF. Transforming growth factor beta1 inhibits cystic fibrosis transmembrane conductance regulator-dependent cAMP-stimulated alveolar epithelial fluid transport via a phosphatidylinositol 3-kinase-dependent mechanism. 2009. PMID: 19996317

  279. Katayama M, Ishizaka A, Sakamoto M, Fujishima S, Sekiguchi K, Asano K, Betsuyaku T, Kotani T, Ware LB, Matthay MA, Hashimoto S. Laminin gamma2 fragments are increased in the circulation of patients with early phase acute lung injury. 2009. PMID: 19940975

  280. Reel B, Oishi PE, Hsu JH, Gildengorin G, Matthay MA, Fineman JR, Flori H. Early elevations in B-type natriuretic peptide levels are associated with poor clinical outcomes in pediatric acute lung injury. 2009. PMID: 19830720

  281. Ware LB, Koyama T, Billheimer DD, Wu W, Bernard GR, Thompson BT, Brower RG, Standiford TJ, Martin TR, Matthay MA. Prognostic and pathogenetic value of combining clinical and biochemical indices in patients with acute lung injury. 2009. PMID: 19858233

  282. Sapru A, Curley MA, Brady S, Matthay MA, Flori H. Elevated PAI-1 is associated with poor clinical outcomes in pediatric patients with acute lung injury. 2009. PMID: 19855955

  283. Looney MR, Nguyen JX, Hu Y, Van Ziffle JA, Lowell CA, Matthay MA. Platelet depletion and aspirin treatment protect mice in a two-event model of transfusion-related acute lung injury. 2009. PMID: 19809160

  284. Lee JW, Gupta N, Serikov V, Matthay MA. Potential application of mesenchymal stem cells in acute lung injury. 2009. PMID: 19691441

  285. Ware LB, Fremont RD, Bastarache JA, Calfee CS, Matthay MA. Determining the aetiology of pulmonary oedema by the oedema fluid-to-plasma protein ratio. 2009. PMID: 19741024

  286. Goolaerts A, Roux J, Ganter MT, Shlyonsky V, Chraibi A, Stéphane R, Mies F, Matthay MA, Naeije R, Sariban-Sohraby S, Howard M, Pittet JF. Serotonin decreases alveolar epithelial fluid transport via a direct inhibition of the epithelial sodium channel. 2009. PMID: 19717814

  287. Colucci G, Domenighetti G, Della Bruna R, Bonilla J, Limoni C, Matthay MA, Martin TR. Comparison of two non-bronchoscopic methods for evaluating inflammation in patients with acute hypoxaemic respiratory failure. 2009. PMID: 19671148

  288. Carnesecchi S, Deffert C, Pagano A, Garrido-Urbani S, Métrailler-Ruchonnet I, Schäppi M, Donati Y, Matthay MA, Krause KH, Barazzone Argiroffo C. NADPH oxidase-1 plays a crucial role in hyperoxia-induced acute lung injury in mice. 2009. PMID: 19661248

  289. Liu KD, Looney MR, Matthay MA. Inhaled activated protein C: a novel therapy for acute lung injury? 2009. PMID: 19519935

  290. Neyrinck AP, Liu KD, Howard JP, Matthay MA. Protective mechanisms of activated protein C in severe inflammatory disorders. 2009. PMID: 19466992

  291. Sapru A, Hansen H, Ajayi T, Brown R, Garcia O, Zhuo H, Wiemels J, Matthay MA, Wiener-Kronish J. 4G/5G polymorphism of plasminogen activator inhibitor-1 gene is associated with mortality in intensive care unit patients with severe pneumonia. 2009. PMID: 19387177

  292. Church GD, Matthay MA, Liu K, Milet M, Flori HR. Blood product transfusions and clinical outcomes in pediatric patients with acute lung injury. 2009. PMID: 19307809

  293. Ong T, Stuart-Killion RB, Daniel BM, Presnell LB, Zhuo H, Matthay MA, Liu KD. Higher pulmonary dead space may predict prolonged mechanical ventilation after cardiac surgery. 2009. PMID: 19382217

  294. Erickson SE, Martin GS, Davis JL, Matthay MA, Eisner MD. Recent trends in acute lung injury mortality: 1996-2005. 2009. PMID: 19325464

  295. Matthay MA. Mesenchymally "stemming" angiogenesis. 2009. PMID: 19406996

  296. Looney MR, Matthay MA. Neutrophil sandwiches injure the microcirculation. 2009. PMID: 19350004

  297. Shyamsundar M, McKeown ST, O'Kane CM, Craig TR, Brown V, Thickett DR, Matthay MA, Taggart CC, Backman JT, Elborn JS, McAuley DF. Simvastatin decreases lipopolysaccharide-induced pulmonary inflammation in healthy volunteers. 2009. PMID: 19324974

  298. Kim SH, Yu W, Mostov K, Matthay MA, Hunt CA. A computational approach to understand in vitro alveolar morphogenesis. 2009. PMID: 19283073

  299. Levitt JE, Gould MK, Ware LB, Matthay MA. The pathogenetic and prognostic value of biologic markers in acute lung injury. 2009. PMID: 19282296

  300. Erickson SE, Shlipak MG, Martin GS, Wheeler AP, Ancukiewicz M, Matthay MA, Eisner MD. Racial and ethnic disparities in mortality from acute lung injury. 2009. PMID: 19050621

  301. Krupa A, Fudala R, Stankowska D, Loyd T, Allen TC, Matthay MA, Gryczynski Z, Gryczynski I, Mettikolla YV, Kurdowska AK. Anti-chemokine autoantibody:chemokine immune complexes activate endothelial cells via IgG receptors. 2008. PMID: 19109244

  302. Iles KE, Wright MM, Cole MP, Welty NE, Ware LB, Matthay MA, Schopfer FJ, Baker PR, Agarwal A, Freeman BA. Fatty acid transduction of nitric oxide signaling: nitrolinoleic acid mediates protective effects through regulation of the ERK pathway. 2008. PMID: 19133325

  303. Glassberg AE, Luce JM, Matthay MA. Reasons for nonenrollment in a clinical trial of acute lung injury. 2008. PMID: 18689583

  304. Calfee CS, Eisner MD, Parsons PE, Thompson BT, Conner ER, Matthay MA, Ware LB. Soluble intercellular adhesion molecule-1 and clinical outcomes in patients with acute lung injury. 2008. PMID: 18670758

  305. Calfee CS, Ware LB, Eisner MD, Parsons PE, Thompson BT, Wickersham N, Matthay MA. Plasma receptor for advanced glycation end products and clinical outcomes in acute lung injury. 2008. PMID: 18566109

  306. Seeley E, McAuley DF, Eisner M, Miletin M, Matthay MA, Kallet RH. Predictors of mortality in acute lung injury during the era of lung protective ventilation. 2008. PMID: 18566110

  307. Liu KD, Levitt J, Zhuo H, Kallet RH, Brady S, Steingrub J, Tidswell M, Siegel MD, Soto G, Peterson MW, Chesnutt MS, Phillips C, Weinacker A, Thompson BT, Eisner MD, Matthay MA. Randomized clinical trial of activated protein C for the treatment of acute lung injury. 2008. PMID: 18565951

  308. Hirsch J, Niemann CU, Hansen KC, Choi S, Su X, Frank JA, Fang X, Hirose R, Theodore P, Sapru A, Burlingame AL, Matthay MA. Alterations in the proteome of pulmonary alveolar type II cells in the rat after hepatic ischemia-reperfusion. Volume 36 of Issue 6. 2008. PMID: 18496381

  309. Su X, Johansen M, Looney MR, Brown EJ, Matthay MA. CD47 deficiency protects mice from lipopolysaccharide-induced acute lung injury and Escherichia coli pneumonia. 2008. PMID: 18453616

  310. Matthay MA, Berthiaume Y. Novel molecular strategy to prevent pulmonary edema. 2008. PMID: 18448936

  311. McClintock D, Zhuo H, Wickersham N, Matthay MA, Ware LB. Biomarkers of inflammation, coagulation and fibrinolysis predict mortality in acute lung injury. 2008. PMID: 18358078

  312. Serikov VB, Mikhaylov VM, Krasnodembskay AD, Matthay MA. Bone marrow-derived cells participate in stromal remodeling of the lung following acute bacterial pneumonia in mice. 2008. PMID: 18357492

  313. Bastarache JA, Wang L, Wang Z, Albertine KH, Matthay MA, Ware LB. Intra-alveolar tissue factor pathway inhibitor is not sufficient to block tissue factor procoagulant activity. 2008. PMID: 18310227

  314. Ganter MT, Roux J, Miyazawa B, Howard M, Frank JA, Su G, Sheppard D, Violette SM, Weinreb PH, Horan GS, Matthay MA, Pittet JF. Interleukin-1beta causes acute lung injury via alphavbeta5 and alphavbeta6 integrin-dependent mechanisms. Volume 102 of Issue 7. 2008. PMID: 18276918

  315. Liu KD, Glidden DV, Eisner MD, Parsons PE, Ware LB, Wheeler A, Korpak A, Thompson BT, Chertow GM, Matthay MA. Predictive and pathogenetic value of plasma biomarkers for acute kidney injury in patients with acute lung injury. 2007. PMID: 18074478

  316. Popov BV, Serikov VB, Petrov NS, Izusova TV, Gupta N, Matthay MA. Lung epithelial cells induce endodermal differentiation in mouse mesenchymal bone marrow stem cells by paracrine mechanism. 2007. PMID: 17630877

  317. Looney MR, Matthay MA. The role of protein C in sepsis. 2007. PMID: 24395479

  318. Calfee CS, Eisner MD, Ware LB, Thompson BT, Parsons PE, Wheeler AP, Korpak A, Matthay MA. Trauma-associated lung injury differs clinically and biologically from acute lung injury due to other clinical disorders. 2007. PMID: 17944012

  319. Frank JA, Pittet JF, Wray C, Matthay MA. Protection from experimental ventilator-induced acute lung injury by IL-1 receptor blockade. Volume 63 of Issue 2. 2007. PMID: 17901159

  320. Liu KD, Datta A, Yu W, Brakeman PR, Jou TS, Matthay MA, Mostov KE. Rac1 is required for reorientation of polarity and lumen formation through a PI 3-kinase-dependent pathway. 2007. PMID: 17804488

  321. Matthay MA, Taeusch W. Surfactant treatment of aspiration-induced lung injury in children. 2007. PMID: 17873790

  322. Ware LB, Matthay MA, Parsons PE, Thompson BT, Januzzi JL, Eisner MD. Pathogenetic and prognostic significance of altered coagulation and fibrinolysis in acute lung injury/acute respiratory distress syndrome. 2007. PMID: 17667242

  323. Pauluhn J, Carson A, Costa DL, Gordon T, Kodavanti U, Last JA, Matthay MA, Pinkerton KE, Sciuto AM. Workshop summary: phosgene-induced pulmonary toxicity revisited: appraisal of early and late markers of pulmonary injury from animal models with emphasis on human significance. 2007. PMID: 17687713

  324. Calfee CS, Budev MM, Matthay MA, Church G, Brady S, Uchida T, Ishizaka A, Lara A, Ranes JL, deCamp MM, Arroliga AC. Plasma receptor for advanced glycation end-products predicts duration of ICU stay and mechanical ventilation in patients after lung transplantation. 2007. PMID: 17613396

  325. Matthay MA, Su X. Pulmonary barriers to pneumonia and sepsis. 2007. PMID: 17618264

  326. Lee JW, Fang X, Dolganov G, Fremont RD, Bastarache JA, Ware LB, Matthay MA. Acute lung injury edema fluid decreases net fluid transport across human alveolar epithelial type II cells. 2007. PMID: 17580309

  327. Cepkova M, Kapur V, Ren X, Quinn T, Zhuo H, Foster E, Liu KD, Matthay MA. Pulmonary dead space fraction and pulmonary artery systolic pressure as early predictors of clinical outcome in acute lung injury. 2007. PMID: 17573490

  328. Berthiaume Y, Matthay MA. Alveolar edema fluid clearance and acute lung injury. 2007. PMID: 17604701

  329. Fudala R, Krupa A, Matthay MA, Allen TC, Kurdowska AK. Anti-IL-8 autoantibody:IL-8 immune complexes suppress spontaneous apoptosis of neutrophils. 2007. PMID: 17513455

  330. Brohi K, Cohen MJ, Ganter MT, Matthay MA, Mackersie RC, Pittet JF. Acute traumatic coagulopathy: initiated by hypoperfusion: modulated through the protein C pathway? 2007. PMID: 17457176

  331. Li CJ, Ning W, Matthay MA, Feghali-Bostwick CA, Choi AM. MAPK pathway mediates EGR-1-HSP70-dependent cigarette smoke-induced chemokine production. 2007. PMID: 17494953

  332. Raj JU, Aliferis C, Caprioli RM, Cowley AW, Davies PF, Duncan MW, Erle DJ, Erzurum SC, Finn PW, Ischiropoulos H, Kaminski N, Kleeberger SR, Leikauf GD, Loyd JE, Martin TR, Matalon S, Moore JH, Quackenbush J, Sabo-Attwood T, Shapiro SD, Schnitzer JE, Schwartz DA, Schwiebert LM, Sheppard D, Ware LB, Weiss ST, Whitsett JA, Wurfel MM, Matthay MA. Genomics and proteomics of lung disease: conference summary. Volume 293 of Issue 1. 2007. PMID: 17468134

  333. Su X, Lee JW, Matthay ZA, Mednick G, Uchida T, Fang X, Gupta N, Matthay MA. Activation of the alpha7 nAChR reduces acid-induced acute lung injury in mice and rats. 2007. PMID: 17431097

  334. Fremont RD, Kallet RH, Matthay MA, Ware LB. Postobstructive pulmonary edema: a case for hydrostatic mechanisms. 2007. PMID: 17413051

  335. Hirsch J, Hansen KC, Sapru A, Frank JA, Chalkley RJ, Fang X, Trinidad JC, Baker P, Burlingame AL, Matthay MA. Impact of low and high tidal volumes on the rat alveolar epithelial type II cell proteome. Volume 175 of Issue 10. 2007. PMID: 17363773

  336. Bastarache JA, Wang L, Geiser T, Wang Z, Albertine KH, Matthay MA, Ware LB. The alveolar epithelium can initiate the extrinsic coagulation cascade through expression of tissue factor. 2007. PMID: 17356058

  337. Frank JA, Briot R, Lee JW, Ishizaka A, Uchida T, Matthay MA. Physiological and biochemical markers of alveolar epithelial barrier dysfunction in perfused human lungs. Volume 293 of Issue 1. 2007. PMID: 17351061

  338. Yu W, Fang X, Ewald A, Wong K, Hunt CA, Werb Z, Matthay MA, Mostov K. Formation of cysts by alveolar type II cells in three-dimensional culture reveals a novel mechanism for epithelial morphogenesis. 2007. PMID: 17332496

  339. Calfee CS, Matthay MA. Nonventilatory treatments for acute lung injury and ARDS. 2007. PMID: 17356114

  340. Heresi GA, Arroliga AC, Wiedemann HP, Weidemann HP, Matthay MA. Pulmonary artery catheter and fluid management in acute lung injury and the acute respiratory distress syndrome. 2006. PMID: 17085251

  341. Ning W, Dong Y, Sun J, Li C, Matthay MA, Feghali-Bostwick CA, Choi AM. Cigarette smoke stimulates matrix metalloproteinase-2 activity via EGR-1 in human lung fibroblasts. 2006. PMID: 17099140

  342. Wang L, Bastarache JA, Wickersham N, Fang X, Matthay MA, Ware LB. Novel role of the human alveolar epithelium in regulating intra-alveolar coagulation. 2006. PMID: 17099142

  343. Bhandari V, Choo-Wing R, Lee CG, Zhu Z, Nedrelow JH, Chupp GL, Zhang X, Matthay MA, Ware LB, Homer RJ, Lee PJ, Geick A, de Fougerolles AR, Elias JA. Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death. 2006. PMID: 17086189

  344. McClintock DE, Ware LB, Eisner MD, Wickersham N, Thompson BT, Matthay MA. Higher urine nitric oxide is associated with improved outcomes in patients with acute lung injury. 2006. PMID: 17082495

  345. Su G, Hodnett M, Wu N, Atakilit A, Kosinski C, Godzich M, Huang XZ, Kim JK, Frank JA, Matthay MA, Sheppard D, Pittet JF. Integrin alphavbeta5 regulates lung vascular permeability and pulmonary endothelial barrier function. Volume 36 of Issue 3. 2006. PMID: 17079779

  346. Lee JW, Matthay MA. Protein permeability in lung injury: now in real time again? 2006. PMID: 17068211

  347. Frank JA, Wray CM, McAuley DF, Schwendener R, Matthay MA. Alveolar macrophages contribute to alveolar barrier dysfunction in ventilator-induced lung injury. Volume 291 of Issue 6. 2006. PMID: 16877636

  348. Godzich M, Hodnett M, Frank JA, Su G, Pespeni M, Angel A, Howard MB, Matthay MA, Pittet JF. Activation of the stress protein response prevents the development of pulmonary edema by inhibiting VEGF cell signaling in a model of lung ischemia-reperfusion injury in rats. Volume 20 of Issue 9. 2006. PMID: 16793871

  349. Jenkins RG, Su X, Su G, Scotton CJ, Camerer E, Laurent GJ, Davis GE, Chambers RC, Matthay MA, Sheppard D. Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury. Volume 116 of Issue 6. 2006. PMID: 16710477

  350. Looney MR, Su X, Van Ziffle JA, Lowell CA, Matthay MA. Neutrophils and their Fc gamma receptors are essential in a mouse model of transfusion-related acute lung injury. 2006. PMID: 16710475

  351. McClintock DE, Starcher B, Eisner MD, Thompson BT, Hayden DL, Church GD, Matthay MA. Higher urine desmosine levels are associated with mortality in patients with acute lung injury. 2006. PMID: 16698854

  352. Guidot DM, Folkesson HG, Jain L, Sznajder JI, Pittet JF, Matthay MA. Integrating acute lung injury and regulation of alveolar fluid clearance. 2006. PMID: 16698856

  353. Ganter MT, Ware LB, Howard M, Roux J, Gartland B, Matthay MA, Fleshner M, Pittet JF. Extracellular heat shock protein 72 is a marker of the stress protein response in acute lung injury. 2006. PMID: 16679378

  354. Adler KB, Shapiro SD, Gallup M, Wu R, Randell SH, Holtzman MJ, Evans CM, Jacoby DB, Tesfaigzi Y, Rose MC, Mossman BT, Prince A, Reddy SP, Davis CW, Matthay MA. Airway epithelium, inflammation, and mechanisms of disease: A tribute to Carol B. Basbaum. 2006. PMID: 16618787

  355. Looney MR, Matthay MA. Animal models of transfusion-related acute lung injury. 2006. PMID: 16617257

  356. Ware LB, Camerer E, Welty-Wolf K, Schultz MJ, Matthay MA. Bench to bedside: targeting coagulation and fibrinolysis in acute lung injury. 2006. PMID: 16648240

  357. Matthay MA, Christman JW, Pitt BR, Schwiebert LM, Stevens T, Ware LB. Perspectives, translational research, and letters to the editor. 2006. PMID: 16531563

  358. Folkesson HG, Matthay MA. Alveolar epithelial ion and fluid transport: recent progress. 2006. PMID: 16514116

  359. Curley MA, Arnold JH, Thompson JE, Fackler JC, Grant MJ, Fineman LD, Cvijanovich N, Barr FE, Molitor-Kirsch S, Steinhorn DM, Matthay MA, Hibberd PL. Clinical trial design--effect of prone positioning on clinical outcomes in infants and children with acute respiratory distress syndrome. 2006. PMID: 16616620

  360. Sakuma T, Gu X, Wang Z, Maeda S, Sugita M, Sagawa M, Osanai K, Toga H, Ware LB, Folkesson G, Matthay MA. Stimulation of alveolar epithelial fluid clearance in human lungs by exogenous epinephrine. 2006. PMID: 16505652

  361. Hirsch J, Hansen KC, Choi S, Noh J, Hirose R, Roberts JP, Matthay MA, Burlingame AL, Maher JJ, Niemann CU. Warm ischemia-induced alterations in oxidative and inflammatory proteins in hepatic Kupffer cells in rats. Volume 5 of Issue 6. 2006. PMID: 16500929

  362. Uchida T, Shirasawa M, Ware LB, Kojima K, Hata Y, Makita K, Mednick G, Matthay ZA, Matthay MA. Receptor for advanced glycation end-products is a marker of type I cell injury in acute lung injury. 2006. PMID: 16456142

  363. Ware LB, Matthay MA. Clinical practice. Acute pulmonary edema. 2005. PMID: 16382065

  364. Han B, Mura M, Andrade CF, Okutani D, Lodyga M, dos Santos CC, Keshavjee S, Matthay M, Liu M. TNFalpha-induced long pentraxin PTX3 expression in human lung epithelial cells via JNK. 2005. PMID: 16339571

  365. Folkesson HG, Chapin CJ, Beard LL, Ertsey R, Matthay MA, Kitterman JA. Congenital diaphragmatic hernia prevents absorption of distal air space fluid in late-gestation rat fetuses. 2005. PMID: 16214817

  366. Ware LB, Fang X, Wang Y, Babcock WD, Jones K, Matthay MA. High prevalence of pulmonary arterial thrombi in donor lungs rejected for transplantation. 2005. PMID: 16210143

  367. Fang X, Song Y, Hirsch J, Galietta LJ, Pedemonte N, Zemans RL, Dolganov G, Verkman AS, Matthay MA. Contribution of CFTR to apical-basolateral fluid transport in cultured human alveolar epithelial type II cells. 2005. PMID: 16143588

  368. Su X, Camerer E, Hamilton JR, Coughlin SR, Matthay MA. Protease-activated receptor-2 activation induces acute lung inflammation by neuropeptide-dependent mechanisms. 2005. PMID: 16081834

  369. Frank JA, Matthay MA. Leukotrienes in acute lung injury: a potential therapeutic target? Volume 172 of Issue 3. 2005. PMID: 16040787

  370. Curley MA, Hibberd PL, Fineman LD, Wypij D, Shih MC, Thompson JE, Grant MJ, Barr FE, Cvijanovich NZ, Sorce L, Luckett PM, Matthay MA, Arnold JH. Effect of prone positioning on clinical outcomes in children with acute lung injury: a randomized controlled trial. 2005. PMID: 16014597

  371. Ware LB, Kaner RJ, Crystal RG, Schane R, Trivedi NN, McAuley D, Matthay MA. VEGF levels in the alveolar compartment do not distinguish between ARDS and hydrostatic pulmonary oedema. 2005. PMID: 15994395

  372. Calfee CS, Matthay MA. Recent advances in mechanical ventilation. 2005. PMID: 15922687

  373. Suzuki T, Moraes TJ, Vachon E, Ginzberg HH, Huang TT, Matthay MA, Hollenberg MD, Marshall J, McCulloch CA, Abreu MT, Chow CW, Downey GP. Proteinase-activated receptor-1 mediates elastase-induced apoptosis of human lung epithelial cells. 2005. PMID: 15891109

  374. Looney MR, Sartori C, Chakraborty S, James PF, Lingrel JB, Matthay MA. Decreased expression of both the alpha1- and alpha2-subunits of the Na-K-ATPase reduces maximal alveolar epithelial fluid clearance. 2005. PMID: 15781423

  375. Angus D, Ishizaka A, Matthay M, Lemaire F, Macnee W, Abraham E. Critical care in AJRCCM 2004. 2005. PMID: 15753483

  376. Roux J, Kawakatsu H, Gartland B, Pespeni M, Sheppard D, Matthay MA, Canessa CM, Pittet JF. Interleukin-1beta decreases expression of the epithelial sodium channel alpha-subunit in alveolar epithelial cells via a p38 MAPK-dependent signaling pathway. Volume 280 of Issue 19. 2005. PMID: 15755725

  377. Planès C, Leyvraz C, Uchida T, Angelova MA, Vuagniaux G, Hummler E, Matthay M, Clerici C, Rossier B. In vitro and in vivo regulation of transepithelial lung alveolar sodium transport by serine proteases. 2005. PMID: 15681398

  378. Cheng IW, Eisner MD, Thompson BT, Ware LB, Matthay MA. Acute effects of tidal volume strategy on hemodynamics, fluid balance, and sedation in acute lung injury. 2005. PMID: 15644650

  379. Matthay MA, Robriquet L, Fang X. Alveolar epithelium: role in lung fluid balance and acute lung injury. 2005. PMID: 16222039

  380. Frank JA, McAuley DF, Gutierrez JA, Daniel BM, Dobbs L, Matthay MA. Differential effects of sustained inflation recruitment maneuvers on alveolar epithelial and lung endothelial injury. Volume 33 of Issue 1. 2005. PMID: 15644667

  381. Parsons PE, Eisner MD, Thompson BT, Matthay MA, Ancukiewicz M, Bernard GR, Wheeler AP. Lower tidal volume ventilation and plasma cytokine markers of inflammation in patients with acute lung injury. 2005. PMID: 15644641

  382. Dezfulian C, Shojania K, Collard HR, Kim HM, Matthay MA, Saint S. Subglottic secretion drainage for preventing ventilator-associated pneumonia: a meta-analysis. 2005. PMID: 15639202

  383. Flori HR, Glidden DV, Rutherford GW, Matthay MA. Pediatric acute lung injury: prospective evaluation of risk factors associated with mortality. Volume 171 of Issue 9. 2004. PMID: 15618461

  384. Mehta D, Bhattacharya J, Matthay MA, Malik AB. Integrated control of lung fluid balance. 2004. PMID: 15531757

  385. Lee H, Pespeni M, Roux J, Dennery PA, Matthay MA, Pittet JF. HO-1 induction restores c-AMP-dependent lung epithelial fluid transport following severe hemorrhage in rats. 2004. PMID: 15550551

  386. Matthay MA, Ware LB. Can nicotine treat sepsis? 2004. PMID: 15516907

  387. Bandi VD, Munnur U, Matthay MA. Acute lung injury and acute respiratory distress syndrome in pregnancy. 2004. PMID: 15388190

  388. Pugin J, Stern-Voeffray S, Daubeuf B, Matthay MA, Elson G, Dunn-Siegrist I. Soluble MD-2 activity in plasma from patients with severe sepsis and septic shock. 2004. PMID: 15328161

  389. Brower RG, Lanken PN, MacIntyre N, Matthay MA, Morris A, Ancukiewicz M, Schoenfeld D, Thompson BT. Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome. 2004. PMID: 15269312

  390. Matthay MA, Clements JA. Coagulation-dependent mechanisms and asthma. 2004. PMID: 15232607

  391. Hirsch J, Hansen KC, Burlingame AL, Matthay MA. Proteomics: current techniques and potential applications to lung disease. 2004. PMID: 15187006

  392. Looney MR, Gropper MA, Matthay MA. Transfusion-related acute lung injury: a review. 2004. PMID: 15249468

  393. Ware LB, Eisner MD, Thompson BT, Parsons PE, Matthay MA. Significance of von Willebrand factor in septic and nonseptic patients with acute lung injury. 2004. PMID: 15201135

  394. Geiser T, Ishigaki M, van Leer C, Matthay MA, Broaddus VC. H(2)O(2) inhibits alveolar epithelial wound repair in vitro by induction of apoptosis. 2004. PMID: 15121637

  395. Hastings RH, Folkesson HG, Matthay MA. Mechanisms of alveolar protein clearance in the intact lung. 2004. PMID: 15003932

  396. Fang X, Song Y, Zemans R, Hirsch J, Matthay MA. Fluid transport across cultured rat alveolar epithelial cells: a novel in vitro system. 2004. PMID: 14990396

  397. Sakuma T, Zhao Y, Sugita M, Sagawa M, Toga H, Ishibashi T, Nishio M, Matthay MA. Malnutrition impairs alveolar fluid clearance in rat lungs. 2004. PMID: 14977628

  398. Olman MA, White KE, Ware LB, Simmons WL, Benveniste EN, Zhu S, Pugin J, Matthay MA. Pulmonary edema fluid from patients with early lung injury stimulates fibroblast proliferation through IL-1 beta-induced IL-6 expression. 2004. PMID: 14764742

  399. Bowler RP, Duda B, Chan ED, Enghild JJ, Ware LB, Matthay MA, Duncan MW. Proteomic analysis of pulmonary edema fluid and plasma in patients with acute lung injury. 2004. PMID: 14742308

  400. Garrity-Ryan L, Shafikhani S, Balachandran P, Nguyen L, Oza J, Jakobsen T, Sargent J, Fang X, Cordwell S, Matthay MA, Engel JN. The ADP ribosyltransferase domain of Pseudomonas aeruginosa ExoT contributes to its biological activities. 2004. PMID: 14688136

  401. Goodman RB, Pugin J, Lee JS, Matthay MA. Cytokine-mediated inflammation in acute lung injury. 2003. PMID: 14563354

  402. Pastor CM, Matthay MA, Frossard JL. Pancreatitis-associated acute lung injury: new insights. 2003. PMID: 14665518

  403. Paine R, Wilcoxen SE, Morris SB, Sartori C, Baleeiro CE, Matthay MA, Christensen PJ. Transgenic overexpression of granulocyte macrophage-colony stimulating factor in the lung prevents hyperoxic lung injury. 2003. PMID: 14633611

  404. Brower RG, Morris A, MacIntyre N, Matthay MA, Hayden D, Thompson T, Clemmer T, Lanken PN, Schoenfeld D. Effects of recruitment maneuvers in patients with acute lung injury and acute respiratory distress syndrome ventilated with high positive end-expiratory pressure. 2003. PMID: 14605529

  405. Eisner MD, Parsons P, Matthay MA, Ware L, Greene K. Plasma surfactant protein levels and clinical outcomes in patients with acute lung injury. 2003. PMID: 14586055

  406. Su X, Bai C, Hong Q, Zhu D, He L, Wu J, Ding F, Fang X, Matthay MA. Effect of continuous hemofiltration on hemodynamics, lung inflammation and pulmonary edema in a canine model of acute lung injury. 2003. PMID: 14557856

  407. Cheng IW, Matthay MA. Acute lung injury and the acute respiratory distress syndrome. 2003. PMID: 14601715

  408. Ishizaka A, Matsuda T, Albertine KH, Koh H, Tasaka S, Hasegawa N, Kohno N, Kotani T, Morisaki H, Takeda J, Nakamura M, Fang X, Martin TR, Matthay MA, Hashimoto S. Elevation of KL-6, a lung epithelial cell marker, in plasma and epithelial lining fluid in acute respiratory distress syndrome. 2003. PMID: 12959931

  409. Bowler RP, Velsor LW, Duda B, Chan ED, Abraham E, Ware LB, Matthay MA, Day BJ. Pulmonary edema fluid antioxidants are depressed in acute lung injury. 2003. PMID: 14501961

  410. Frank J, Roux J, Kawakatsu H, Su G, Dagenais A, Berthiaume Y, Howard M, Canessa CM, Fang X, Sheppard D, Matthay MA, Pittet JF. Transforming growth factor-beta1 decreases expression of the epithelial sodium channel alphaENaC and alveolar epithelial vectorial sodium and fluid transport via an ERK1/2-dependent mechanism. Volume 278 of Issue 45. 2003. PMID: 12930837

  411. Elia N, Tapponnier M, Matthay MA, Hamacher J, Pache JC, Brundler MA, Totsch M, De Baetselier P, Fransen L, Fukuda N, Morel DR, Lucas R. Functional identification of the alveolar edema reabsorption activity of murine tumor necrosis factor-alpha. 2003. PMID: 12842853

  412. Ware LB, Fang X, Matthay MA. Protein C and thrombomodulin in human acute lung injury. 2003. PMID: 12754194

  413. Prabhakaran P, Ware LB, White KE, Cross MT, Matthay MA, Olman MA. Elevated levels of plasminogen activator inhibitor-1 in pulmonary edema fluid are associated with mortality in acute lung injury. 2003. PMID: 12730079

  414. Matthay MA, Zimmerman GA, Esmon C, Bhattacharya J, Coller B, Doerschuk CM, Floros J, Gimbrone MA, Hoffman E, Hubmayr RD, Leppert M, Matalon S, Munford R, Parsons P, Slutsky AS, Tracey KJ, Ward P, Gail DB, Harabin AL. Future research directions in acute lung injury: summary of a National Heart, Lung, and Blood Institute working group. 2003. PMID: 12663342

  415. Folkesson HG, Matthay MA. Therapeutic strategies to hasten the resolution of pulmonary edema. 2003. PMID: 12682513

  416. Collard HR, Saint S, Matthay MA. Prevention of ventilator-associated pneumonia: an evidence-based systematic review. 2003. PMID: 12639084

  417. Galiacy S, Planus E, Lepetit H, Féréol S, Laurent V, Ware L, Isabey D, Matthay M, Harf A, d'Ortho MP. Keratinocyte growth factor promotes cell motility during alveolar epithelial repair in vitro. 2003. PMID: 12581741

  418. Frank JA, Pittet JF, Lee H, Godzich M, Matthay MA. High tidal volume ventilation induces NOS2 and impairs cAMP- dependent air space fluid clearance. Volume 284 of Issue 5. 2003. PMID: 12562562

  419. Cheng IW, Ware LB, Greene KE, Nuckton TJ, Eisner MD, Matthay MA. Prognostic value of surfactant proteins A and D in patients with acute lung injury. 2003. PMID: 12544988

  420. Matthay MA. Clinical measurement of pulmonary edema. 2002. PMID: 12475816

  421. Brower RG, Matthay M, Schoenfeld D. Meta-analysis of acute lung injury and acute respiratory distress syndrome trials. 2002. PMID: 12450936

  422. Albertine KH, Soulier MF, Wang Z, Ishizaka A, Hashimoto S, Zimmerman GA, Matthay MA, Ware LB. Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome. 2002. PMID: 12414525

  423. Pham I, Uchida T, Planes C, Ware LB, Kaner R, Matthay MA, Clerici C. Hypoxia upregulates VEGF expression in alveolar epithelial cells in vitro and in vivo. 2002. PMID: 12376368

  424. Sartori C, Fang X, McGraw DW, Koch P, Snider ME, Folkesson HG, Matthay MA. Selected contribution: long-term effects of beta(2)-adrenergic receptor stimulation on alveolar fluid clearance in mice. 2002. PMID: 12381778

  425. Ware LB, Fang X, Wang Y, Sakuma T, Hall TS, Matthay MA. Selected contribution: mechanisms that may stimulate the resolution of alveolar edema in the transplanted human lung. 2002. PMID: 12381777

  426. Frank JA, Matthay MA. Science review: mechanisms of ventilator-induced injury. Volume 7 of Issue 3. 2002. PMID: 12793874

  427. Planès C, Blot-Chabaud M, Matthay MA, Couette S, Uchida T, Clerici C. Hypoxia and beta 2-agonists regulate cell surface expression of the epithelial sodium channel in native alveolar epithelial cells. 2002. PMID: 12372821

  428. Lane RK, Matthay MA. Central line infections. 2002. PMID: 12357113

  429. Matthay MA, Clerici C, Saumon G. Invited review: Active fluid clearance from the distal air spaces of the lung. 2002. PMID: 12235056

  430. Sakuma T, Sagawa M, Hida M, Nambu Y, Osanai K, Toga H, Takahashi K, Ohya N, Matthay MA. Time-dependent effect of pneumonectomy on alveolar epithelial fluid clearance in rat lungs. 2002. PMID: 12324723

  431. Matthay MA, Bhattacharya S, Gaver D, Ware LB, Lim LH, Syrkina O, Eyal F, Hubmayr R. Ventilator-induced lung injury: in vivo and in vitro mechanisms. 2002. PMID: 12225942

  432. Jiang J, Song Y, Bai C, Koller BH, Matthay MA, Verkman AS. Pleural surface fluorescence measurement of Na+ and Cl- transport across the air space-capillary barrier. 2002. PMID: 12391048

  433. Ware LB, Wang Y, Fang X, Warnock M, Sakuma T, Hall TS, Matthay M. Assessment of lungs rejected for transplantation and implications for donor selection. 2002. PMID: 12241936

  434. Fang X, Yang B, Matthay MA, Verkman AS. Evidence against aquaporin-1-dependent CO2 permeability in lung and kidney. 2002. PMID: 12096051

  435. Atabai K, Ishigaki M, Geiser T, Ueki I, Matthay MA, Ware LB. Keratinocyte growth factor can enhance alveolar epithelial repair by nonmitogenic mechanisms. Volume 283 of Issue 1. 2002. PMID: 12060573

  436. Matthay MA, Folkesson HG, Clerici C. Lung epithelial fluid transport and the resolution of pulmonary edema. 2002. PMID: 12087129

  437. Atabai K, Ware LB, Snider ME, Koch P, Daniel B, Nuckton TJ, Matthay MA. Aerosolized beta(2)-adrenergic agonists achieve therapeutic levels in the pulmonary edema fluid of ventilated patients with acute respiratory failure. Volume 28 of Issue 6. 2002. PMID: 12107675

  438. Kurdowska AK, Geiser TK, Alden SM, Dziadek BR, Noble JM, Nuckton TJ, Matthay MA. Activity of pulmonary edema fluid interleukin-8 bound to alpha(2)-macroglobulin in patients with acute lung injury. 2002. PMID: 11943675

  439. Nuckton TJ, Alonso JA, Kallet RH, Daniel BM, Pittet JF, Eisner MD, Matthay MA. Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome. 2002. PMID: 11973365

  440. Eisner MD, Thompson BT, Schoenfeld D, Anzueto A, Matthay MA. Airway pressures and early barotrauma in patients with acute lung injury and acute respiratory distress syndrome. 2002. PMID: 11934725

  441. Matthay MA, Uchida T, Fang X. Clinical Acute Lung Injury and Acute Respiratory Distress Syndrome. 2002. PMID: 11858776

  442. Folkesson HG, Matthay MA, Chapin CJ, Porta NF, Kitterman JA. Distal air space epithelial fluid clearance in near-term rat fetuses is fast and requires endogenous catecholamines. 2002. PMID: 11839545

  443. Laffon M, Jayr C, Barbry P, Wang Y, Folkesson HG, Pittet JF, Clerici C, Matthay MA. Lidocaine induces a reversible decrease in alveolar epithelial fluid clearance in rats. 2002. PMID: 11818773

  444. Fang X, Fukuda N, Barbry P, Sartori C, Verkman AS, Matthay MA. Novel role for CFTR in fluid absorption from the distal airspaces of the lung. 2002. PMID: 11815669

  445. Frank JA, Gutierrez JA, Jones KD, Allen L, Dobbs L, Matthay MA. Low tidal volume reduces epithelial and endothelial injury in acid-injured rat lungs. Volume 165 of Issue 2. 2002. PMID: 11790662

  446. Pittet JF, Lu LN, Geiser T, Lee H, Matthay MA, Welch WJ. Stress preconditioning attenuates oxidative injury to the alveolar epithelium of the lung following haemorrhage in rats. 2002. PMID: 11790821

  447. Thompson BT, Hayden D, Matthay MA, Brower R, Parsons PE. Clinicians' approaches to mechanical ventilation in acute lung injury and ARDS. 2001. PMID: 11713144

  448. Vivona ML, Matthay M, Chabaud MB, Friedlander G, Clerici C. Hypoxia reduces alveolar epithelial sodium and fluid transport in rats: reversal by beta-adrenergic agonist treatment. 2001. PMID: 11713096

  449. McGraw DW, Fukuda N, James PF, Forbes SL, Woo AL, Lingrel JB, Witte DP, Matthay MA, Liggett SB. Targeted transgenic expression of beta(2)-adrenergic receptors to type II cells increases alveolar fluid clearance. 2001. PMID: 11557593

  450. Looney MR, Matthay MA. The Role of Protein C in Sepsis. 2001. PMID: 11559461

  451. Brower RG, Ware LB, Berthiaume Y, Matthay MA. Treatment of ARDS. 2001. PMID: 11591581

  452. Sakuma T, Tuchihara C, Ishigaki M, Osanai K, Nambu Y, Toga H, Takahashi K, Ohya N, Inoue M, Matthay MA. Beta1-adrenoceptor stimulation by high-dose terbutaline downregulates terbutaline-stimulated alveolar fluid clearance in ex vivo rat lung. 2001. PMID: 11480585

  453. Fischer H, Fukuda N, Barbry P, Illek B, Sartori C, Matthay MA. Partial restoration of defective chloride conductance in DeltaF508 CF mice by trimethylamine oxide. 2001. PMID: 11404245

  454. Chesnutt MS, Nuckton TJ, Golden J, Folkesson HG, Matthay MA. Rapid alveolar epithelial fluid clearance following lung lavage in pulmonary alveolar proteinosis. 2001. PMID: 11451848

  455. Fukuda N, Jayr C, Lazrak A, Wang Y, Lucas R, Matalon S, Matthay MA. Mechanisms of TNF-alpha stimulation of amiloride-sensitive sodium transport across alveolar epithelium. 2001. PMID: 11350806

  456. Song Y, Jayaraman S, Yang B, Matthay MA, Verkman AS. Role of aquaporin water channels in airway fluid transport, humidification, and surface liquid hydration. 2001. PMID: 11382807

  457. Pittet JF, Griffiths MJ, Geiser T, Kaminski N, Dalton SL, Huang X, Brown LA, Gotwals PJ, Koteliansky VE, Matthay MA, Sheppard D. TGF-beta is a critical mediator of acute lung injury. Volume 107 of Issue 12. 2001. PMID: 11413161

  458. Pittet JF, Lu LN, Morris DG, Modelska K, Welch WJ, Carey HV, Roux J, Matthay MA. Reactive nitrogen species inhibit alveolar epithelial fluid transport after hemorrhagic shock in rats. 2001. PMID: 11342654

  459. Geiser T, Atabai K, Jarreau PH, Ware LB, Pugin J, Matthay MA. Pulmonary edema fluid from patients with acute lung injury augments in vitro alveolar epithelial repair by an IL-1beta-dependent mechanism. Volume 163 of Issue 6. 2001. PMID: 11371405

  460. Norlin A, Lu LN, Guggino SE, Matthay MA, Folkesson HG. Contribution of amiloride-insensitive pathways to alveolar fluid clearance in adult rats. 2001. PMID: 11247951

  461. Geiser TK, Kazmierczak BI, Garrity-Ryan LK, Matthay MA, Engel JN. Pseudomonas aeruginosa ExoT inhibits in vitro lung epithelial wound repair. 2001. PMID: 11298646

  462. Crandall ED, Matthay MA. Alveolar epithelial transport. Basic science to clinical medicine. 2001. PMID: 11282783

  463. Sakuma T, Tuchihara C, Ishigaki M, Osanai K, Nambu Y, Toga H, Takahashi K, Ohya N, Kurihara T, Matthay MA. Denopamine, a beta(1)-adrenergic agonist, increases alveolar fluid clearance in ex vivo rat and guinea pig lungs. 2001. PMID: 11133887

  464. Geiser T, Jarreau PH, Atabai K, Matthay MA. Interleukin-1beta augments in vitro alveolar epithelial repair. Volume 279 of Issue 6. 2000. PMID: 11076808

  465. Song Y, Yang B, Matthay MA, Ma T, Verkman AS. Role of aquaporin water channels in pleural fluid dynamics. 2000. PMID: 11078688

  466. Frank JA, Wang Y, Osorio O, Matthay MA. Beta-adrenergic agonist therapy accelerates the resolution of hydrostatic pulmonary edema in sheep and rats. Volume 89 of Issue 4. 2000. PMID: 11007557

  467. Matthay MA, Fukuda N, Frank J, Kallet R, Daniel B, Sakuma T. Alveolar epithelial barrier. Role in lung fluid balance in clinical lung injury. Volume 21 of Issue 3. 2000. PMID: 11019721

  468. Frank JA, Nuckton TJ, Matthay MA. Diabetes mellitus: a negative predictor for the development of acute respiratory distress syndrome from septic shock. Volume 28 of Issue 7. 2000. PMID: 10921610

  469. Kaner RJ, Ladetto JV, Singh R, Fukuda N, Matthay MA, Crystal RG. Lung overexpression of the vascular endothelial growth factor gene induces pulmonary edema. 2000. PMID: 10837361

  470. Sakuma T, Tsukano C, Ishigaki M, Nambu Y, Osanai K, Toga H, Takahashi K, Ohya N, Kurihara T, Nishio M, Matthay MA. Lung deflation impairs alveolar epithelial fluid transport in ischemic rabbit and rat lungs. 2000. PMID: 10830212

  471. Ware LB, Matthay MA. The acute respiratory distress syndrome. 2000. PMID: 10793167

  472. Verkman AS, Matthay MA, Song Y. Aquaporin water channels and lung physiology. 2000. PMID: 10781416

  473. Coscoy S, de Weille J, Lingueglia E, Fukuda N, Matthay M, Lazdunski M, Barbry P. [Amiloride-sensitive sodium channel in the nephron and its activation by vasopressin]. 2000. PMID: 10960333

  474. Newman V, Gonzalez RF, Matthay MA, Dobbs LG. A novel alveolar type I cell-specific biochemical marker of human acute lung injury. 2000. PMID: 10712353

  475. Pascual FE, Matthay MA, Bacchetti P, Wachter RM. Assessment of prognosis in patients with community-acquired pneumonia who require mechanical ventilation. 2000. PMID: 10669697

  476. Folkesson HG, Norlin A, Wang Y, Abedinpour P, Matthay MA. Dexamethasone and thyroid hormone pretreatment upregulate alveolar epithelial fluid clearance in adult rats. 2000. PMID: 10658006

  477. Abraham E, Matthay MA, Dinarello CA, Vincent JL, Cohen J, Opal SM, Glauser M, Parsons P, Fisher CJ, Repine JE. Consensus conference definitions for sepsis, septic shock, acute lung injury, and acute respiratory distress syndrome: time for a reevaluation. 2000. PMID: 10667529

  478. Gaillard D, Hinnrasky J, Coscoy S, Hofman P, Matthay MA, Puchelle E, Barbry P. Early expression of beta- and gamma-subunits of epithelial sodium channel during human airway development. 2000. PMID: 10645905

  479. Eberhard LW, Morabito DJ, Matthay MA, Mackersie RC, Campbell AR, Marks JD, Alonso JA, Pittet JF. Initial severity of metabolic acidosis predicts the development of acute lung injury in severely traumatized patients. 2000. PMID: 10667511

  480. Ma T, Fukuda N, Song Y, Matthay MA, Verkman AS. Lung fluid transport in aquaporin-5 knockout mice. 2000. PMID: 10619865

  481. Jasmer RM, Matthay MA. Noninvasive ventilation for acute respiratory failure. 2000. PMID: 12580223

  482. Eisner MD, Matthay MA. Health-related quality of life after acute lung injury. 1999. PMID: 10628634

  483. Modelska K, Pittet JF, Folkesson HG, Courtney Broaddus V, Matthay MA. Acid-induced lung injury. Protective effect of anti-interleukin-8 pretreatment on alveolar epithelial barrier function in rabbits. 1999. PMID: 10556104

  484. Wang Y, Folkesson HG, Jayr C, Ware LB, Matthay MA. Alveolar epithelial fluid transport can be simultaneously upregulated by both KGF and beta-agonist therapy. 1999. PMID: 10562630

  485. Rubenfeld GD, Caldwell E, Granton J, Hudson LD, Matthay MA. Interobserver variability in applying a radiographic definition for ARDS. 1999. PMID: 10559098

  486. Hribar M, Bloc A, van der Goot FG, Fransen L, De Baetselier P, Grau GE, Bluethmann H, Matthay MA, Dunant Y, Pugin J, Lucas R. The lectin-like domain of tumor necrosis factor-alpha increases membrane conductance in microvascular endothelial cells and peritoneal macrophages. 1999. PMID: 10540321

  487. Berthiaume Y, Folkesson HG, Matthay MA. Indomethacin does not influence alveolar liquid clearance in anesthetized sheep or rats. 1999. PMID: 10533677

  488. Matthay MA, Geiser T, Matalon S, Ischiropoulos H. Oxidant-mediated lung injury in the acute respiratory distress syndrome. 1999. PMID: 10507639

  489. Khan SU, Salloum J, O'Donovan PB, Mascha EJ, Mehta AC, Matthay MA, Arroliga AC. Acute pulmonary edema after lung transplantation: the pulmonary reimplantation response. 1999. PMID: 10424524

  490. Matthay MA. Conference summary: acute lung injury. 1999. PMID: 10424631

  491. Modelska K, Matthay MA, Brown LA, Deutch E, Lu LN, Pittet JF. Inhibition of beta-adrenergic-dependent alveolar epithelial clearance by oxidant mechanisms after hemorrhagic shock. 1999. PMID: 10330041

  492. Ware LB, Golden JA, Finkbeiner WE, Matthay MA. Alveolar epithelial fluid transport capacity in reperfusion lung injury after lung transplantation. 1999. PMID: 10051282

  493. Munger JS, Huang X, Kawakatsu H, Griffiths MJ, Dalton SL, Wu J, Pittet JF, Kaminski N, Garat C, Matthay MA, Rifkin DB, Sheppard D. The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis. Volume 96 of Issue 3. 1999. PMID: 10025398

  494. Bai C, Fukuda N, Song Y, Ma T, Matthay MA, Verkman AS. Lung fluid transport in aquaporin-1 and aquaporin-4 knockout mice. 1999. PMID: 10021464

  495. Campbell AR, Folkesson HG, Berthiaume Y, Gutkowska J, Suzuki S, Matthay MA. Alveolar epithelial fluid clearance persists in the presence of moderate left atrial hypertension in sheep. 1999. PMID: 9887124

  496. Sakuma T, Takahashi K, Ohya N, Kajikawa O, Martin TR, Albertine KH, Matthay MA. Ischemia-reperfusion lung injury in rabbits: mechanisms of injury and protection. 1999. PMID: 9887066

  497. Yang B, Folkesson HG, Yang J, Matthay MA, Ma T, Verkman AS. Reduced osmotic water permeability of the peritoneal barrier in aquaporin-1 knockout mice. 1999. PMID: 9886922

  498. Planus E, Galiacy S, Matthay M, Laurent V, Gavrilovic J, Murphy G, Clérici C, Isabey D, Lafuma C, d'Ortho MP. Role of collagenase in mediating in vitro alveolar epithelial wound repair. 1999. PMID: 9858477

  499. Saint S, Matthay MA. Risk reduction in the intensive care unit. 1998. PMID: 9870839

  500. Matthay MA, Flori HR, Conner ER, Ware LB. Alveolar epithelial fluid transport: basic mechanisms and clinical relevance. 1998. PMID: 9824532

  501. Folkesson HG, Nitenberg G, Oliver BL, Jayr C, Albertine KH, Matthay MA. Upregulation of alveolar epithelial fluid transport after subacute lung injury in rats from bleomycin. 1998. PMID: 9728042

  502. Parsons PE, Matthay M. Protective ventilation for the acute respiratory distress syndrome. 1998. PMID: 9669913

  503. Bai C, Biwersi J, Verkman AS, Matthay MA. A mouse model to test the in vivo efficacy of chemical chaperones. 1998. PMID: 9920533

  504. Garat C, Carter EP, Matthay MA. New in situ mouse model to quantify alveolar epithelial fluid clearance. 1998. PMID: 9572828

  505. Artigas A, Bernard GR, Carlet J, Dreyfuss D, Gattinoni L, Hudson L, Lamy M, Marini JJ, Matthay MA, Pinsky MR, Spragg R, Suter PM. The American-European Consensus Conference on ARDS, part 2. Ventilatory, pharmacologic, supportive therapy, study design strategies and issues related to recovery and remodeling. 1998. PMID: 9609420

  506. Artigas A, Bernard GR, Carlet J, Dreyfuss D, Gattinoni L, Hudson L, Lamy M, Marini JJ, Matthay MA, Pinsky MR, Spragg R, Suter PM. The American-European Consensus Conference on ARDS, part 2: Ventilatory, pharmacologic, supportive therapy, study design strategies, and issues related to recovery and remodeling. Acute respiratory distress syndrome. 1998. PMID: 9563759

  507. Carter EP, Umenishi F, Matthay MA, Verkman AS. Developmental changes in water permeability across the alveolar barrier in perinatal rabbit lung. 1997. PMID: 9276723

  508. Tibayan FA, Chesnutt AN, Folkesson HG, Eandi J, Matthay MA. Dobutamine increases alveolar liquid clearance in ventilated rats by beta-2 receptor stimulation. 1997. PMID: 9279221

  509. Modelska K, Matthay MA, McElroy MC, Pittet JF. Upregulation of alveolar liquid clearance after fluid resuscitation for hemorrhagic shock in rats. 1997. PMID: 9277441

  510. Garat C, Meignan M, Matthay MA, Luo DF, Jayr C. Alveolar epithelial fluid clearance mechanisms are intact after moderate hyperoxic lung injury in rats. 1997. PMID: 9149598

  511. Pittet JF, Mackersie RC, Martin TR, Matthay MA. Biological markers of acute lung injury: prognostic and pathogenetic significance. 1997. PMID: 9105054

  512. Chesnutt AN, Kheradmand F, Folkesson HG, Alberts M, Matthay MA. Soluble transforming growth factor-alpha is present in the pulmonary edema fluid of patients with acute lung injury. 1997. PMID: 9118703

  513. Sakuma T, Folkesson HG, Suzuki S, Okaniwa G, Fujimura S, Matthay MA. Beta-adrenergic agonist stimulated alveolar fluid clearance in ex vivo human and rat lungs. 1997. PMID: 9032186

  514. Rezaiguia S, Garat C, Delclaux C, Meignan M, Fleury J, Legrand P, Matthay MA, Jayr C. Acute bacterial pneumonia in rats increases alveolar epithelial fluid clearance by a tumor necrosis factor-alpha-dependent mechanism. 1997. PMID: 9006001

  515. Sakuma T, Usuda K, Handa M, Okaniwa G, Nakada T, Fujimura S, Matthay MA. Increased alveolar fluid clearance following thoracotomy: report of a case and results of an analysis. 1997. PMID: 9306595

  516. Umenishi F, Carter EP, Yang B, Oliver B, Matthay MA, Verkman AS. Sharp increase in rat lung water channel expression in the perinatal period. 1996. PMID: 8918374

  517. Garat C, Kheradmand F, Albertine KH, Folkesson HG, Matthay MA. Soluble and insoluble fibronectin increases alveolar epithelial wound healing in vitro. 1996. PMID: 8944729

  518. Kurdowska A, Miller EJ, Noble JM, Baughman RP, Matthay MA, Brelsford WG, Cohen AB. Anti-IL-8 autoantibodies in alveolar fluid from patients with the adult respiratory distress syndrome. 1996. PMID: 8805676

  519. Pittet JF, Brenner TJ, Modelska K, Matthay MA. Alveolar liquid clearance is increased by endogenous catecholamines in hemorrhagic shock in rats. 1996. PMID: 8872653

  520. Folkesson HG, Pittet JF, Nitenberg G, Matthay MA. Transforming growth factor-alpha increases alveolar liquid clearance in anesthetized ventilated rats. 1996. PMID: 8770062

  521. Matthay MA. The acute respiratory distress syndrome. 1996. PMID: 8618587

  522. Folkesson HG, Matthay MA, Weström BR, Kim KJ, Karlsson BW, Hastings RH. Alveolar epithelial clearance of protein. 1996. PMID: 8727524

  523. Sakuma T, Suzuki S, Usuda K, Handa M, Okaniwa G, Nakada T, Fujimura S, Matthay MA. Preservation of alveolar epithelial fluid transport mechanisms in rewarmed human lung after severe hypothermia. 1996. PMID: 8727555

  524. DiFederico EM, Harrison M, Matthay MA. Pulmonary edema in a woman following fetal surgery. 1996. PMID: 8635343

  525. Matthay MA, Folkesson HG, Verkman AS. Salt and water transport across alveolar and distal airway epithelia in the adult lung. 1996. PMID: 8928808

  526. Corry DB, Folkesson HG, Warnock ML, Erle DJ, Matthay MA, Wiener-Kronish JP, Locksley RM. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. Volume 183 of Issue 1. 1996. PMID: 8551213

  527. Garat C, Rezaiguia S, Meignan M, D'Ortho MP, Harf A, Matthay MA, Jayr C. Alveolar endotoxin increases alveolar liquid clearance in rats. 1995. PMID: 8847269

  528. Doyle RL, Szaflarski N, Modin GW, Wiener-Kronish JP, Matthay MA. Identification of patients with acute lung injury. Predictors of mortality. 1995. PMID: 8520742

  529. Hastings RH, Folkesson HG, Petersen V, Ciriales R, Matthay MA. Cellular uptake of albumin from lungs of anesthetized rabbits. 1995. PMID: 7485517

  530. Folkesson HG, Matthay MA, Hébert CA, Broaddus VC. Acid aspiration-induced lung injury in rabbits is mediated by interleukin-8-dependent mechanisms. 1995. PMID: 7615779

  531. Rubenfeld GD, Doyle RL, Matthay MA. Evaluation of definitions of ARDS. 1995. PMID: 7697267

  532. Pittet JF, Wiener-Kronish JP, Serikov V, Matthay MA. Resistance of the alveolar epithelium to injury from septic shock in sheep. 1995. PMID: 7697237

  533. Schnapp LM, Chin DP, Szaflarski N, Matthay MA. Frequency and importance of barotrauma in 100 patients with acute lung injury. 1995. PMID: 7867352

  534. Folkesson HG, Kheradmand F, Matthay MA. The effect of salt water on alveolar epithelial barrier function. 1994. PMID: 7952614

  535. Kheradmand F, Folkesson HG, Shum L, Derynk R, Pytela R, Matthay MA. Transforming growth factor-alpha enhances alveolar epithelial cell repair in a new in vitro model. 1994. PMID: 7810677

  536. Sakuma T, Okaniwa G, Nakada T, Nishimura T, Fujimura S, Matthay MA. Alveolar fluid clearance in the resected human lung. 1994. PMID: 8049807

  537. Pittet JF, Wiener-Kronish JP, McElroy MC, Folkesson HG, Matthay MA. Stimulation of lung epithelial liquid clearance by endogenous release of catecholamines in septic shock in anesthetized rats. 1994. PMID: 8040320

  538. Jayr C, Garat C, Meignan M, Pittet JF, Zelter M, Matthay MA. Alveolar liquid and protein clearance in anesthetized ventilated rats. 1994. PMID: 7928894

  539. Folkesson HG, Matthay MA, Hasegawa H, Kheradmand F, Verkman AS. Transcellular water transport in lung alveolar epithelium through mercury-sensitive water channels. 1994. PMID: 7515184

  540. Hastings RH, Wright JR, Albertine KH, Ciriales R, Matthay MA. Effect of endocytosis inhibitors on alveolar clearance of albumin, immunoglobulin G, and SP-A in rabbits. 1994. PMID: 8203547

  541. Hasegawa H, Ma T, Skach W, Matthay MA, Verkman AS. Molecular cloning of a mercurial-insensitive water channel expressed in selected water-transporting tissues. 1994. PMID: 7509789

  542. Matthay MA, Folkesson HG, Campagna A, Kheradmand F. Alveolar epithelial barrier and acute lung injury. 1993. PMID: 8087581

  543. Matthay MA, Thiery JP, Lafont F, Stampfer F, Boyer B. Transient effect of epidermal growth factor on the motility of an immortalized mammary epithelial cell line. 1993. PMID: 8308069

  544. Wiener-Kronish JP, Sakuma T, Kudoh I, Pittet JF, Frank D, Dobbs L, Vasil ML, Matthay MA. Alveolar epithelial injury and pleural empyema in acute P. aeruginosa pneumonia in anesthetized rabbits. 1993. PMID: 8282618

  545. Cohen AB, Stevens MD, Miller EJ, Atkinson MA, Mullenbach G, Maunder RJ, Martin TR, Wiener-Kronish JP, Matthay MA. Neutrophil-activating peptide-2 in patients with pulmonary edema from congestive heart failure or ARDS. 1993. PMID: 8498526

  546. Newman W, Beall LD, Carson CW, Hunder GG, Graben N, Randhawa ZI, Gopal TV, Wiener-Kronish J, Matthay MA. Soluble E-selectin is found in supernatants of activated endothelial cells and is elevated in the serum of patients with septic shock. 1993. PMID: 7678280

  547. Sakuma T, Pittet JF, Jayr C, Matthay MA. Alveolar liquid and protein clearance in the absence of blood flow or ventilation in sheep. 1993. PMID: 7680335

  548. Hastings RH, Grady M, Sakuma T, Matthay MA. Clearance of different-sized proteins from the alveolar space in humans and rabbits. 1992. PMID: 1447074

  549. Espiritu RF, Pittet JF, Matthay MA, Goetzl EJ. Neuropeptides in pulmonary edema fluid of adult respiratory distress syndrome. 1992. PMID: 1428125

  550. Cohen DS, Matthay MA, Cogan MG, Murray JF. Pulmonary edema associated with salt water near-drowning: new insights. 1992. PMID: 1519866

  551. Segredo V, Caldwell JE, Matthay MA, Sharma ML, Gruenke LD, Miller RD. Persistent paralysis in critically ill patients after long-term administration of vecuronium. 1992. PMID: 1353252

  552. Miller EJ, Cohen AB, Nagao S, Griffith D, Maunder RJ, Martin TR, Weiner-Kronish JP, Sticherling M, Christophers E, Matthay MA. Elevated levels of NAP-1/interleukin-8 are present in the airspaces of patients with the adult respiratory distress syndrome and are associated with increased mortality. 1992. PMID: 1489135

  553. Kilpatrick SJ, Matthay MA. Obstetric patients requiring critical care. A five-year review. 1992. PMID: 1582306

  554. Matthay MA, Matthay RA. Critical care medicine. 1991. PMID: 2041115

  555. Smedira N, Gates L, Hastings R, Jayr C, Sakuma T, Pittet JF, Matthay MA. Alveolar and lung liquid clearance in anesthetized rabbits. 1991. PMID: 2055861

  556. Matthay MA. Resolution of pulmonary edema. New insights. 1991. PMID: 2028590

  557. Rubin DB, Wiener-Kronish JP, Murray JF, Green DR, Turner J, Luce JM, Montgomery AB, Marks JD, Matthay MA. Elevated von Willebrand factor antigen is an early plasma predictor of acute lung injury in nonpulmonary sepsis syndrome. 1990. PMID: 2384595

  558. Wiener-Kronish JP, Gropper MA, Matthay MA. The adult respiratory distress syndrome: definition and prognosis, pathogenesis and treatment. 1990. PMID: 2200479

  559. Segredo V, Matthay MA, Sharma ML, Gruenke LD, Caldwell JE, Miller RD. Prolonged neuromuscular blockade after long-term administration of vecuronium in two critically ill patients. 1990. PMID: 1968730

  560. Brüssel T, Matthay MA, Chernow B. Pulmonary manifestations of endocrine and metabolic disorders. 1989. PMID: 2689069

  561. Berthiaume Y, Albertine KH, Grady M, Fick G, Matthay MA. Protein clearance from the air spaces and lungs of unanesthetized sheep over 144 h. 1989. PMID: 2600023

  562. Matthay MA, Wiener-Kronish JP. Respiratory management after cardiac surgery. 1989. PMID: 2914495

  563. Wiener-Kronish JP, Broaddus VC, Albertine KH, Gropper MA, Matthay MA, Staub NC. Relationship of pleural effusions to increased permeability pulmonary edema in anesthetized sheep. 1988. PMID: 3170750

  564. Murray JF, Matthay MA, Luce JM, Flick MR. An expanded definition of the adult respiratory distress syndrome. 1988. PMID: 3202424

  565. Berthiaume Y, Broaddus VC, Gropper MA, Tanita T, Matthay MA. Alveolar liquid and protein clearance from normal dog lungs. 1988. PMID: 3170409

  566. Ratnoff WD, Matthay MA, Wong MY, Ito Y, Vu KH, Wiener-Kronish J, Goetzl EJ. Sulfidopeptide-leukotriene peptidases in pulmonary edema fluid from patients with the adult respiratory distress syndrome. 1988. PMID: 2842367

  567. Wiener-Kronish JP, Goldstein R, Matthay RA, Biondi JW, Broaddus VC, Chatterjee K, Matthay MA. Lack of association of pleural effusion with chronic pulmonary arterial and right atrial hypertension. 1987. PMID: 3677841

  568. Dean NC, Amend WC, Matthay MA. Adult respiratory distress syndrome related to antilymphocyte globulin therapy. 1987. PMID: 3549177

  569. Berthiaume Y, Staub NC, Matthay MA. Beta-adrenergic agonists increase lung liquid clearance in anesthetized sheep. 1987. PMID: 2879851

  570. Biondi JW, Hines RL, Barash PG, Baker CC, Matthay MA, Matthay RA. The adult respiratory distress syndrome. 1986. PMID: 3538681

  571. Curtis JL, Mahlmeister M, Fink JB, Lampe G, Matthay MA, Stulbarg MS. Helium-oxygen gas therapy. Use and availability for the emergency treatment of inoperable airway obstruction. 1986. PMID: 3743166

  572. Fein A, Wiener-Kronish JP, Niederman M, Matthay MA. Pathophysiology of the adult respiratory distress syndrome. What have we learned from human studies? 1986. PMID: 3331557

  573. Hansen RM, Viquerat CE, Matthay MA, Wiener-Kronish JP, DeMarco T, Bahtia S, Marks JD, Botvinick EH, Chatterjee K. Poor correlation between pulmonary arterial wedge pressure and left ventricular end-diastolic volume after coronary artery bypass graft surgery. 1986. PMID: 3487261

  574. Bigby TD, Serota ML, Tierney LM, Matthay MA. Clinical spectrum of pulmonary mucormycosis. 1986. PMID: 3081299

  575. Swerdlow BN, Mihm FG, Goetzl EJ, Matthay MA. Leukotrienes in pulmonary edema fluid after cardiopulmonary bypass. 1986. PMID: 3006549

  576. Eisendrath SJ, Link N, Matthay M. Intensive care unit: how stressful for physicians? 1986. PMID: 3943330

  577. Wiener-Kronish JP, Matthay MA, Callen PW, Filly RA, Gamsu G, Staub NC. Relationship of pleural effusions to pulmonary hemodynamics in patients with congestive heart failure. 1985. PMID: 3907444

  578. Matthay MA, Berthiaume Y, Staub NC. Long-term clearance of liquid and protein from the lungs of unanesthetized sheep. 1985. PMID: 4055578

  579. Matthay MA. Pathophysiology of pulmonary edema. 1985. PMID: 3907942

  580. Viquerat CE, Hansen RM, Botvinick EH, Dae MW, Wiener-Kronish JP, Matthay MA. Undrained bloody pericardial effusion in the early postoperative period after coronary bypass surgery: a prospective blood pool study. 1985. PMID: 3875274

  581. Weinberg PF, Matthay MA, Webster RO, Roskos KV, Goldstein IM, Murray JF. Biologically active products of complement and acute lung injury in patients with the sepsis syndrome. 1984. PMID: 6497161

  582. Colice GL, Matthay MA, Bass E, Matthay RA. Neurogenic pulmonary edema. 1984. PMID: 6388446

  583. Bongard FS, Matthay M, Mackersie RC, Lewis FR. Morphologic and physiologic correlates of increased extravascular lung water. 1984. PMID: 6463867

  584. Wiedemann HP, Matthay MA, Matthay RA. Cardiovascular-pulmonary monitoring in the intensive care unit (Part 2). 1984. PMID: 6713975

  585. Wiedemann HP, Matthay MA, Matthay RA. Cardiovascular-pulmonary monitoring in the intensive care unit (Part 1). 1984. PMID: 6368142

  586. Eisendrath SJ, Matthay MA, Dunkel JA, Zimmerman JK, Layzer RB. Guillain-Barré syndrome: psychosocial aspects of management. 1983. PMID: 6878601

  587. Prewitt RM, Matthay MA, Ghignone M. Hemodynamic management in the adult respiratory distress syndrome. 1983. PMID: 6342923

  588. Landolt CC, Matthay MA, Albertine KH, Roos PJ, Wiener-Kronish JP, Staub NC. Overperfusion, hypoxia, and increased pressure cause only hydrostatic pulmonary edema in anesthetized sheep. 1983. PMID: 6825224

  589. Matthay MA, Landolt CC, Staub NC. Differential liquid and protein clearance from the alveoli of anesthetized sheep. 1982. PMID: 7118651

  590. Russell J, Follansbee S, Matthay M. Adult respiratory distress syndrome complicating diabetic ketoacidosis. 1981. PMID: 6792789

  591. Landolt CC, Matthay MA, Staub NC. Anatomic variations of efferent duct from caudal mediastinal lymph node in sheep. 1981. PMID: 7263401

  592. Matthay MA, Addison TE, Ellinger G, Choy SH, Kaltreider HB. Chest mass with pleurisy. 1979. PMID: 477435

  593. Matthay M, Lindamood M, Steigerwald JC, Solomons C. Acute pseudogout in the absence of synovial fluid Leukocytes. 1977. PMID: 926107

  594. Matthay MA, Matthay RA, Mills DM, Lakshminarayan S, Cotton E. Hypertrophic osteoarthropathy in adults with cystic fibrosis. 1976. PMID: 996819

  595. Matthay RA, Matthay MA, Weinberger MM. Grand mal seizure induced by oral theophylline. 1976. PMID: 823660