Events on December 14, 2017

Medicine Grand Rounds

Approaches to Hypermidichlorianemia and Undiagnosed Diseases Matthew Wheeler, MD

Clinical Assistant Professor, Stanford University

Medical Director of the Center for Undiagnosed Diseases

http://tiny.ucsf.edu/MGR17stream

*Give examples of the use of exome and genome sequencing in the diagnostic work up

*Recognize patients with undiagnosed diseases and approaches to evaluation

*Describe an approach to defining diagnostic certainty

Dr. Matthew Wheeler is Clinical Assistant Professor and Medical Director of the Center for Undiagnosed Diseases at Stanford University in Stanford, California. An expert in cardiovascular genetics, he has clinical interest in advanced heart failure and inherited cardiomyopathies. His background includes research in myocardial and skeletal muscle biology as well as molecular genetics and genomics. He has extensive translational science experience, participating in ongoing clinical trials for hypertrophic cardiomyopathy, dilated cardiomyopathy, cardiac amyloidosis, and mechanical circulatory support. In genetics and genomics, he has led analysis of whole genome and whole exome sequencing focusing on identifying clinically actionable rare and novel variants, first from whole genome sequencing of a single patient and now in cohorts of inherited cardiomyopathy and undiagnosed disease patients. He is the Adult Medical Director of Stanford’s NIH-funded Center for Undiagnosed Diseases and a core member of the Undiagnosed Diseases Network. He teaches physician and genetic counselor trainees on genomic medicine and approach to undiagnosed diseases. In addition to his work in genetics and genomics of disease, he is a member of the Bioinformatics Core of the Molecular Transducers of Physical Activity Consortium, whose goal is to create a multiomic map of the response to physical activity, and co-PI on the Exercise at the Limit – Inherited Traits of Endurance, a project whose goal is to identify the genetic contributors to human performance.
HSW-300 + Add to calendar

Incubator: ARCHES "The Acute-to-Recovery Care for Hospitalized Elders Study"

| Ryan Greysen, Andy Auerbach, James Harrison M989 + Add to calendar

Cath Lab Conference

Presentation will be given by Alexandra (Jay) Teng M-1179 + Add to calendar

Geriatrics Works in Progress

Drs. Lynn Flint, Daniel David and Alex Smith UCSF Laurel Heights 4th Floor, Room 474, 3333 California St, San Francisco, CA 94118 + Add to calendar