Medicine Grand RoundsWhat does CRISPR mean for Cardiologists? Bruce Conklin*, MD
Gladstone Scientific Officer, Research Technology & Innovation
Senior Investigator, Gladstone
Professor, UCSF Departments of Medicine and Ophthalmology
Deputy Director, Innovative Genomics Institute
*What is CRISPR?
*What does CRISPR technology mean for understanding disease?
*How can CRISPR technology be used to cure disease?
Dr. Conklin’s research focuses on genome engineering to identify novel therapeutic approaches to human disease. By making precise genetic changes in induced pluripotent cells he seeks to reveal the cellular and molecular mechanisms of disease and identify new methods for therapeutic editing. He began his research career by working for two years at NIH with Julius Axelrod, Ph.D., (Nobel Laureate). He then completed his residency at Johns Hopkins Hospital and a postdoctoral fellowship in the laboratory of Henry Bourne, M.D. at UCSF. In 1995 Dr. Conklin joined the Gladstone Institutes and the UCSF faculty where he is now a Senior Investigator at Gladstone, and a Professor at UCSF. Dr. Conklin is also the Gladstone Scientific Officer for Technology & Innovation and the deputy director of the Innovative Genomics Institute. He is the founder BayGenomics, GenMAPP, AltAnalyze and WikiPathways. He pioneered the field of chemogenetics using designer GPCRs (RASSLs). He founded the Gladstone Genomics and Stem Cell Cores. He advises multiple organizations including the Allen Institute for Cell Science, Chinese University of Hong Kong, and the SF Exploratorium. He is a Fellow in the California Academy of Sciences and a member the American Society for Clinical Investigation.
*Faculty Relationship Disclosure:
Bruce Conklin, MD, Tenaya Therapeutics – Co-Founder, Advisor, Stock Holder
Switch Bio – Scientific Advisor, Stock Holder
Scientist.com – Scientific Advisor, Stock Holder
Cellogy, Inc. – Scientific Advisor, Stock Holder HSW-300 + Add to calendar