Center for Clinical Informatics and Improvement Research (CLIIR)


The newly established Center for Clinical Informatics and Improvement Research (CLIIR) was created out of a critical need to understand how to use digital tools to improve quality and value.

CLIIR’s mission is to discover ways: (1) to leverage EHRs and other sources of digital data to improve clinical performance and healthcare value, and (2) to scale these results to promote healthcare transformation. 

CLIIR will provide a learning lab for UCSF as well as establish UCSF as a leading academic research and policy hub in this domain.

CLIIR’s main efforts will revolve around

  • Examination of how EHR use impacts clinical care processes and outcomes, to inform development of new tools, technologies and care protocols
  • Assessment of how new IT tools can change care processes and targeted outcomes to fulfill delivery and payment reform goals
  • Experimentation in approaches to bring knowledge from precision medicine and other domains of data science to the frontlines of care

Job Opportunities

How to Apply:
Please email Anjali Garg at with your:

  • Cover Letter including description of research interests and career goals
  • Resume/CV
  • Contact Information for 3 References

Motivation for CLIIR

In just the past five years, the U.S. healthcare system has gone from paper-based to largely digital. While the growing pains are obvious, the transition from paper to digital has the capacity to transform care.

Four stages are needed for this to occur:

(1) Digitization: Digital collection and storage of healthcare information through EHRs, other clinical IT systems, and patient-facing systems;

(2) Interoperability & Integration: Connecting systems (enterprise to enterprise systems, apps/sensors to enterprise systems; patient-facing systems to one another and to enterprise systems) and integrating social and environmental information;

(3) Analytics: Using digital information to generate new knowledge about making care better, safer, more accessible, and less expensive;

(4) Learning Health System: feeding new knowledge into health care to enable delivery of high-value care and a healthcare system that iteratively improves. Strategies that will create learning health systems will involve new technology applications – clinical decision support, artificial intelligence, telehealth, patient engagement tools – as well as new healthcare processes, organizational configurations, and workforce capabilities.

As a nation, we’re at the end of Stage 1, and early into Stage 2. We’ve just scratched the surface on Stage 3. Stage 4, the hardest and most disruptive of all, is nascent; however, we are gaining insights into the challenges and opportunities to complete this last stage of the journey from digitization to excellence and value.

UCSF is uniquely positioned to accelerate progress in the first three stages, and to lay the foundation for the last stage to achieve the full benefit of the digital revolution.

CLIIR is excited to learn about the clinical informatics-related work that is happening across the campus and health system.

Please contact us at to learn more and explore potential collaborations.

We look forward to getting to know you!

Our Team

Julia Adler-Milstein, PhD
Associate Professor, Department of Medicine

Anna Vantsevich, MHI
Assistant Director of the Center for Clinical Informatics and Improvement Research


Anjali Garg, MS
Assistant Director of the Center for Clinical Informatics and Improvement Research


Contact Us

Anna Vantsevich, MHI
Assistant Director, Center for Clinical Informatics and Improvement Research
University of California, San Francisco (UCSF)