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University of California, San Francisco
400 Parnassus Avenue, Plaza Level
San Francisco, CA. 94143-0326
Email: kenfye@itsa.ucsf.edu
Education
University of California, Berkeley B.A. 1960 – 1964 Zoology
University of California, San Francisco M.D. 1964-1968 Medicine
Medical Societies
•
National Arthritis Foundation, past member of the National Research
Committee
• Northern California Chapter of the Arthritis Foundation,
Past Chairman of the Chapter and Chairman of the Medical and Scientific
Committee
• Faculty-Alumni Association, University of California San
Francisco, Past President, 2001-2002
Selected Research
Proctor
and Gamble. 10/14/99 to present. Randomized, double-blinded, parallel,
multi-center, placebo-controlled study to determine the efficacy
and safety of orally administered 5 and 15 mg/day and 50 mg/week
risedronate in patients with dual compartment knee osteoarthritis
in North America.
Briston
Myers Squib. 4/10/00 to 1/1/03. A multicenter, randomized, double-blind,
placebo controlled study to evaluate the safe and clinical efficacy
of intravenous infusions of BMS-188667 (2 mg/kg) given monthly in
combination with subcutaneous injections of etanercept (25 mg) given
twice weekly to subjects with active rheumatoid arthritis.
Scios.
10/01/02 to present. A phase II multi-center, randomized, double-blind,
placebo-controlled, dose escalating study of SCIO-469 in patients
with active rheumatoid arthritis receiving methotrexate.
Merck.
4/6/02 to present. Etoricoxib vs diclofenac sodium gastrointestinal
tolerability and effectiveness (EDGE) trial. A randomized, double-blind,
multi-center study to evaluate the tolerability and effectiveness
of etoricoxib 90 mg qd vs diclofenac sodium 50 mg tid in patients
with osteoarthritis.
Selected
Publications
Fye
KH: “A Review of the Vasculititic Disorders Associated with
Antineutrophil Cytoplasmic Antibodies.” Rheumatology Review
3:141-148, 1994.
Fye
KH, Weinstein PR, Donald F. "Compressive Cervical Myelopathy
Due to Calcium Pyrophosphate Dihydate Deposition Disease."
Arch Int Med 159: 189-193, 1999.
Fye
KH. "New Treatments for Rheumatoid Arthritis: Available and
Upcoming Slow-acting Antirheumatic Drugs". Postgrad Med 106:82-92,
1999.
Seligman
VA, Bolton PB, Sanchez HC, Fye KH. Propylthiouracil-Induced Microscopic
Polyangiitis. J. Clin. Rheum. 7:170-174, 2001.
Cunnane
G., Warnock M., Fye KH., Daikh DI : Accelerated nodulosis and vasculitis
following etancerpt therapy for rheumatoid arthritis. Arth Rheum
(Arth Care Research) 47:445-449, 2002.
Fye,
KH. Recognizing the extra articular manifestations of RA: Journal
Musculoskeletal Med. Vol. 19 307-316, 2002
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