Richard Locksley , M.D.
Sandler Distinguished Professor of Medicine and Microbiology/Immunology
Investigator, Howard Hughes Medical Institute
Director, Sandler Asthma Basic Research Center
locksley@medicine.ucsf.edu

Mailing Address:
University of California, San Francisco
Division of Infectious Diseases
513 Parnassus Avenue, Room S-1032B
San Francisco, CA 94143-0654

Office Location:
Medical Sciences Building, S-1032B

Research Interests:
Cytokine expression and regulation in immune cells in response to infectious and inflammatory agents.

Select Publications:

Locksley RM, NJ Killeen, MJ Lenardo.  2001.  The TNF and TNF receptor superfamilies:  integrating mammalian biology.  Cell 104:487-501.

Shinkai K, M Mohrs, RM Locksley. 2002.  Helper T cells regulate type 2 immunity in vivo.  Nature 420:825-9.

Voehringer D, K Shinkai, RM Locksley.  2004.  Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production.  Immunity 20:267-77.

Xu M, ZE Wang, RM Locksley.  2004.  Innate Immune responses in peptidoglycan-recognition-protein-L-deficient mice.  Mol Cell Biol 24:7949-57.

Voehringer D, DB Rosen, LL Lanier, RM Locksley.  2004.  CD200R family members represent novel DAP12-associated activating receptors on basophils and mast cells.  J Biol Chem 279:54117-23.

Education and Training:

M.D., University of Rochester, 1976

Residency, Chief Residency, University of California, San Francisco, 1976-80

ID Fellowship, University of Washington, Seattle, 1980-83

Relevant Links:

http://www.ucsf.edu/immuno/faculty/locksley.html

http://www.ucsf.edu/bms/immunology.html

http://cc.ucsf.edu/people/locksley_richard.html

http://www.hhmi.org/research/investigators/locksley_bio.html

Dr. Locksley is also a recipient of the 2005 Excellence in Direct Teaching Award.