Jane E. Koehler, M.A., M.D.
Professor of Medicine
jkoehler@medicine.ucsf.edu

Mailing Address:
University of California, San Francisco
Division of Infectious Diseases
521 Parnassus Avenue, Room C-443
San Francisco, CA 94143-0654

Office Location:
Health Sciences East Building - HSE401

Research Interests:
Regulation of virulence gene expression in Bartonella; and interactions between host cells and the Bartonella species that cause cat scratch disease and bacillary angiomatosis

Select Publications:

Park, S.Y., K.L. Kelminson, A.K. Lee, P. Zhang, R.E. Warner, D. Rehkopf, S.B. Calderwood and J.E. Koehler.  “Identification, characterization and functional analysis of a gene encoding the ferric uptake regulation protein in Bartonella species,” Journal of Bacteriology, 183:5751-5755 (2001).

Chang, C-c., B.B. Chomel,R.W. Kasten, J.W. Tappero, M.A. Sanchez and J.E. Koehler. “Molecular epidemiology of Bartonella henselae infection in HIV-infected patients and their cat contacts using pulsed field gel electrophoresis and genotyping,” Journal of Infectious Diseases, 186:1733-1739 (2002).

Koehler, J.E., M.A. Sanchez, S. Tye, C.S. Garrido-Rowland, F.M. Chen, T. Maurer, J.L. Cooper, J.G. Olson, A.L. Reingold, W.K. Hadley, R.R. Regnery and J.W. Tappero. "Prevalence of Bartonella infection among HIV-infected patients with fever," Clinical Infectious Diseases, 37:559-66 (2003).

Rolain, J.M., P. Brouqui, J.E. Koehler, C. Maguina, M.J. Dolan and D. Raoult.  “Recommendations for treatment of human infections caused by Bartonella species,” Antimicrobial Agents and Chemotherapy, 48:1921-1933 (2004).  [Peer-reviewed treatment consensus statement]

Zhang, P., B.B. Chomel, M.K. Schau, J.S. Goo, S. Droz, K.L. Kelminson, S.S. George, N.W. Lerche and J.E. Koehler.  “A family of variably expressed outer-membrane proteins (Vomp) mediates adhesion and autoaggregation in Bartonella quintana,” Proceedings of the National Academy of Sciences USA, 101:13630-13635 (2004).

Education and Training:

M.A., Microbiology, University of California, Berkeley, 1978

M.D., George Washington University, 1984

Residency, University of California, San Francisco, 1984-1987

Infectious Diseases Fellowship and Postdoctoral Training, University of California, San Francisco, 1987-1992

Relevant Links:

http://medicine.ucsf.edu/id/koehlerlab

http://www.ucsf.edu/micro/pathogenesis/index.htm

http://www.ucsf.edu/bms/faculty/koehler.html